Hypoxia induces an autocrine-paracrine survival pathway via platelet-derived growth factor (PDGF)-B/PDGF-beta receptor/phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells.

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Volumn 17, Issue 12, 2003, Pages 1709-1711

  Zhang, Shelley X L ^a   Gozal, David ^a   Sachleben Jr , Leroy R ^a   Rane, Madhavi ^a   Klein, Jon B ^a   Gozal, Evelyne ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL HYPOXIA; CELL LINE; CELL SURVIVAL; CULTURE MEDIUM; ENZYMOLOGY; KINETICS; METABOLISM; NERVE CELL; PARACRINE SIGNALING; PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; AUTOCRINE COMMUNICATION; CELL HYPOXIA; CELL LINE; CELL SURVIVAL; CULTURE MEDIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KINETICS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NEURONS; PARACRINE COMMUNICATION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-SIS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; TRANSCRIPTION FACTORS;

MLCS; MLOWN;

EID: 0141818115     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.02-1111fje     Document Type: Article

References (0)