Na+ channel pharmacology and molecular mechanisms of gating

Current Pharmaceutical Design

Volumn 12, Issue 4, 2006, Pages 429-442

  Yamaoka, K ^a   Vogel, S M ^b   Seyama, I ^c  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF ILLINOIS   (United States)

^c Hiroshima Jogakuin University   (Japan)

Author keywords

Inactivation gate; Membrane depolarization; Methanethiosulfonate; Myocytes; Tetrodotoxin

Indexed keywords

ACONITINE; ANTIARRHYTHMIC AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; BATRACHOTOXIN; BREVETOXIN; CHLORPHENOTANE; CIGUATOXIN; CONOTOXIN; DELTA CONOTOXIN; GRAYANOTOXIN; LAMOTRIGINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; MEMBRANE LIPID; MU CONOTOXIN; PYRETHROID; SAXITOXIN; SCORPION VENOM; SEA ANEMONE TOXIN; SODIUM ION; TETRODOTOXIN; UNCLASSIFIED DRUG; VERATRIDINE; VOLTAGE GATED SODIUM CHANNEL; NEUROTOXIN; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

BINDING SITE; CELL MEMBRANE STEADY POTENTIAL; CHANNEL GATING; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HUMAN; MEMBRANE ELECTROPHYSIOLOGY; MEMBRANE STRUCTURE; MOLECULAR DYNAMICS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SODIUM TRANSPORT; TISSUE DISTRIBUTION; TOXIN STRUCTURE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; PHYSIOLOGY;

ANIMALS; BINDING SITES; HUMANS; ION CHANNEL GATING; MODELS, MOLECULAR; NEUROTOXINS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 33644884999     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161206775474468     Document Type: Review

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