A quantitative and comparative study of the effects of a synthetic ciguatoxin CTX3C on the kinetic properties of voltage-dependent sodium channels

British Journal of Pharmacology

Volumn 142, Issue 5, 2004, Pages 879-889

  Yamaoka, Kaoru ^a   Inoue, Masayuki ^b   Miyahara, Hidemichi ^a   Miyazaki, Keisuke ^b   Hirama, Masahiro ^b  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Brevetoxin; Ciguatoxin; Na v1.5; Na v1.2; Na v1.4; Slow inactivation

Indexed keywords

CIGUATOXIN; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; CELL MEMBRANE POTENTIAL; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIELECTRIC CONSTANT; DRUG DISTRIBUTION; DRUG EFFECT; DRUG MEGADOSE; DRUG SCREENING; HUMAN; HUMAN CELL; HYPERPOLARIZATION; LIPOPHILICITY; MAXIMUM ALLOWABLE CONCENTRATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STATISTICAL SIGNIFICANCE;

ANIMALS; CELL LINE; CIGUATOXINS; DNA, COMPLEMENTARY; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; HUMANS; ION CHANNEL GATING; ISOMERISM; KINETICS; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PERFUSION; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TRANSFECTION;

EID: 3242889662     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705852     Document Type: Article

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