메뉴 건너뛰기




Volumn 337, Issue 1, 2003, Pages 41-45

Involvement of local anesthetic binding sites on IVS6 of sodium channels in fast and slow inactivation

Author keywords

Binding site; Inactivation; Local anesthetic; Mutagenesis; Patch clamp; Sodium channel

Indexed keywords

LOCAL ANESTHETIC AGENT; SODIUM CHANNEL;

EID: 0037472352     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)01288-0     Document Type: Article
Times cited : (24)

References (20)
  • 2
    • 0030465187 scopus 로고    scopus 로고
    • Local anesthetics as effectors of allosteric gating: Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels
    • Balser J.R., Nuss H.B., Orias D.W., Johns D.C., Marban E., Tomaselli G.F., Lawrence J.H. Local anesthetics as effectors of allosteric gating: lidocaine effects on inactivation-deficient rat skeletal muscle Na channels. J. Clin. Invest. 98:1996;2874-2886.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2874-2886
    • Balser, J.R.1    Nuss, H.B.2    Orias, D.W.3    Johns, D.C.4    Marban, E.5    Tomaselli, G.F.6    Lawrence, J.H.7
  • 3
    • 0029879866 scopus 로고    scopus 로고
    • Functional consequences of lidocaine binding to slow-inactivated sodium channels
    • Balser J.R., Nuss H.B., Romashko D.N., Marban E., Tomaselli G.F. Functional consequences of lidocaine binding to slow-inactivated sodium channels. J. Gen. Physiol. 107:1996;643-658.
    • (1996) J. Gen. Physiol. , vol.107 , pp. 643-658
    • Balser, J.R.1    Nuss, H.B.2    Romashko, D.N.3    Marban, E.4    Tomaselli, G.F.5
  • 4
    • 0020624782 scopus 로고
    • Lidocaine block of cardiac sodium channels
    • Bean B.P., Cohen C.J., Tsien R.W. Lidocaine block of cardiac sodium channels. J. Gen. Physiol. 81:1983;613-642.
    • (1983) J. Gen. Physiol. , vol.81 , pp. 613-642
    • Bean, B.P.1    Cohen, C.J.2    Tsien, R.W.3
  • 7
    • 0029730718 scopus 로고    scopus 로고
    • Interaction between fast and slow inactivation in Skm1 sodium channels
    • Featherstone D.E., Richmond J.E., Ruben P.C. Interaction between fast and slow inactivation in Skm1 sodium channels. Biophys. J. 71:1996;3098-3109.
    • (1996) Biophys. J. , vol.71 , pp. 3098-3109
    • Featherstone, D.E.1    Richmond, J.E.2    Ruben, P.C.3
  • 8
    • 0031052231 scopus 로고    scopus 로고
    • Slow inactivation differs among mutant Na channels associated with myotonia and periodic paralysis
    • Hayward L.J., Brown R.H. Jr, Cannon S.C. Slow inactivation differs among mutant Na channels associated with myotonia and periodic paralysis. Biophys. J. 72:1997;1204-1219.
    • (1997) Biophys. J. , vol.72 , pp. 1204-1219
    • Hayward, L.J.1    Brown R.H., Jr.2    Cannon, S.C.3
  • 9
    • 0017332486 scopus 로고
    • Local anesthetics: Hydrophilic and hydrophobic pathways for the drug-receptor reaction
    • Hille B. Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. J. Gen. Physiol. 69:1977;497-515.
    • (1977) J. Gen. Physiol. , vol.69 , pp. 497-515
    • Hille, B.1
  • 10
    • 0017726385 scopus 로고
    • Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels
    • Hondeghem L.M., Katzung B.G. Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels. Biochim. Biophys. Acta. 472:1977;373-398.
    • (1977) Biochim. Biophys. Acta , vol.472 , pp. 373-398
    • Hondeghem, L.M.1    Katzung, B.G.2
  • 11
    • 0029044707 scopus 로고
    • A critical role for transmembrane segment IVS6 of the sodium channel α subunit in fast inactivation
    • McPhee J.C., Ragsdale D.S., Scheuer T., Catterall W.A. A critical role for transmembrane segment IVS6 of the sodium channel α subunit in fast inactivation. J. Biol. Chem. 270:1995;12025-12034.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12025-12034
    • McPhee, J.C.1    Ragsdale, D.S.2    Scheuer, T.3    Catterall, W.A.4
  • 12
    • 0034128858 scopus 로고    scopus 로고
    • A point mutation in domain 4-segment 6 of the skeletal muscle sodium channel produces an atypical inactivation state
    • O'Reilly J.P., Wang S.-Y., Wang G.K. A point mutation in domain 4-segment 6 of the skeletal muscle sodium channel produces an atypical inactivation state. Biophys. J. 78:2000;773-784.
    • (2000) Biophys. J. , vol.78 , pp. 773-784
    • O'Reilly, J.P.1    Wang, S.-Y.2    Wang, G.K.3
  • 14
    • 0018196425 scopus 로고
    • Slow inactivation of the sodium conductance in squid giant axons: Pronase resistance
    • Rudy B. Slow inactivation of the sodium conductance in squid giant axons: pronase resistance. J. Physiol. 283:1978;1-21.
    • (1978) J. Physiol. , vol.283 , pp. 1-21
    • Rudy, B.1
  • 15
    • 0035056966 scopus 로고    scopus 로고
    • Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics
    • Sunami A., Glaaser I.W., Fozzard H.A. Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics. Mol. Pharmacol. 59:2001;684-691.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 684-691
    • Sunami, A.1    Glaaser, I.W.2    Fozzard, H.A.3
  • 16
    • 0012395175 scopus 로고    scopus 로고
    • The structure and orientation of domain IV S6 in sodium channel determined by cysteine scanning mutagenesis
    • Sunami A., Glaaser I.W., Lipkind G.M., Fozzard H.A. The structure and orientation of domain IV S6 in sodium channel determined by cysteine scanning mutagenesis. Circulation. 104:2001;2-216.
    • (2001) Circulation , vol.104 , pp. 2-216
    • Sunami, A.1    Glaaser, I.W.2    Lipkind, G.M.3    Fozzard, H.A.4
  • 19
    • 0342547301 scopus 로고    scopus 로고
    • A mutation in segment I-S6 alters slow inactivation of sodium channels
    • Wang S.-Y., Wang G.K. A mutation in segment I-S6 alters slow inactivation of sodium channels. Biophys. J. 72:1997;1633-1640.
    • (1997) Biophys. J. , vol.72 , pp. 1633-1640
    • Wang, S.-Y.1    Wang, G.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.