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Volumn 66, Issue 5, 1999, Pages 733-739

The peroxisome proliferator-activated receptorγ (PPARγ) as a regulator of monocyte/macrophage function

Author keywords

Atherosclerosis; Inflammatory response; Nuclear receptor; Transcription factors

Indexed keywords

FATTY ACID; HORMONE RECEPTOR; ICOSANOID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; STEROID RECEPTOR; THYROID HORMONE RECEPTOR; TRANSCRIPTION FACTOR;

EID: 0032737858     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.66.5.733     Document Type: Conference Paper
Times cited : (290)

References (86)
  • 2
    • 0029182179 scopus 로고
    • The molecular and genetic dissection of the retinoid signaling pathway
    • Chambon, P. (1995) The molecular and genetic dissection of the retinoid signaling pathway. Recent Prog. Horm. Res. 50, 317-332.
    • (1995) Recent Prog. Horm. Res. , vol.50 , pp. 317-332
    • Chambon, P.1
  • 3
    • 0028332036 scopus 로고
    • Differential recognition of target genes by nuclear receptor monomers, dimers and heterodimers
    • Glass, C. K. (1994) Differential recognition of target genes by nuclear receptor monomers, dimers and heterodimers. Endocr. Rev. 15, 1503-1519.
    • (1994) Endocr. Rev. , vol.15 , pp. 1503-1519
    • Glass, C.K.1
  • 4
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer, S. A., Umesono, K., Noonan, D. J., Heyman, R. A., Evans, R. M. (1992) Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 358, 771-774.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 5
    • 0027161015 scopus 로고
    • PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene
    • Bardot, O., Aldridge, T. C., Latruffe, N., Green, S. (1993) PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. Biochem. Biophys. Res. Commun. 192, 37-45.
    • (1993) Biochem. Biophys. Res. Commun. , vol.192 , pp. 37-45
    • Bardot, O.1    Aldridge, T.C.2    Latruffe, N.3    Green, S.4
  • 7
    • 0027525576 scopus 로고
    • The peroxisome proliferator-activated receptor retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs
    • Issemann, I., Prince, R. A., Tugwood, J. D., Green, S. (1993) The peroxisome proliferator-activated receptor retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs. J. Mol. Endocrinol. 11, 37-47.
    • (1993) J. Mol. Endocrinol. , vol.11 , pp. 37-47
    • Issemann, I.1    Prince, R.A.2    Tugwood, J.D.3    Green, S.4
  • 9
    • 0029294531 scopus 로고
    • Peroxisome proliferator activated receptors: Transcriptional regulators of adipogenesis, lipid metabolism and more
    • Wahli, W., Braissant, O., Desvergne, B. (1995) Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more. Chem. Biol. 2, 261-266.
    • (1995) Chem. Biol. , vol.2 , pp. 261-266
    • Wahli, W.1    Braissant, O.2    Desvergne, B.3
  • 10
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, -γ in the adult rat
    • Braissant, O., Foufelle, F., Scotto, C., Dauca, M., Wahli, W. (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α, -β, -γ in the adult rat. Endocrinol. 137, 354-366.
    • (1996) Endocrinol. , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 11
    • 0029994543 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
    • Schoonjans, K., Staels, B., Auwerx, J. (1996) Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. J. Lipid Res. 37, 907-925.
    • (1996) J. Lipid Res. , vol.37 , pp. 907-925
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 12
    • 0029731662 scopus 로고    scopus 로고
    • PPARs: A nuclear receptor signaling pathway in lipid metabolism
    • Lemberger, T., Desvergne, B., Wahli, W. (1996) PPARs: a nuclear receptor signaling pathway in lipid metabolism. Annu. Rev. Cell Dev. Biol. 12, 335-363.
    • (1996) Annu. Rev. Cell Dev. Biol. , vol.12 , pp. 335-363
    • Lemberger, T.1    Desvergne, B.2    Wahli, W.3
  • 13
    • 0028015713 scopus 로고
    • Peroxisome proliferator-activated receptor γ: Adipose-predominant expression and induction early in adipocyte differentiation
    • Chawla, A., Schwartz, E. J., Dimaculangan, D. D., Lazar, M. A. (1994) Peroxisome proliferator-activated receptor γ: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinol. 135, 798-800.
    • (1994) Endocrinol. , vol.135 , pp. 798-800
    • Chawla, A.1    Schwartz, E.J.2    Dimaculangan, D.D.3    Lazar, M.A.4
  • 14
    • 0028180070 scopus 로고
    • mPPAR gamma 2: Tissue-specific regulator of an adipocyte enhancer
    • Tontonoz, P., Hu, E., Graves, R. A., Budavari, A. I., Spiegelman, B. M. (1994) mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev. 8, 1224-1234.
    • (1994) Genes Dev. , vol.8 , pp. 1224-1234
    • Tontonoz, P.1    Hu, E.2    Graves, R.A.3    Budavari, A.I.4    Spiegelman, B.M.5
  • 15
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
    • Tontonoz, P., Hu, E., Spiegelman, B. M. (1994) Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 79, 1147-1156.
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 16
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPARgamma)
    • Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., Kliewer, S. A. (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPARgamma). J. Biol. Chem. 270, 12953-12956.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 17
    • 0030062325 scopus 로고    scopus 로고
    • The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones
    • Willson, T. M., Cobb, J. E., Cowan, D. J., Wiethe, R. W., Correa, I. D., Prakash, S. R., Beck, K. D., Moore, L. B., Kliewer, S. A., Lehmann, J. M. (1996) The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J. Med. Chem. 39, 665-668.
    • (1996) J. Med. Chem. , vol.39 , pp. 665-668
    • Willson, T.M.1    Cobb, J.E.2    Cowan, D.J.3    Wiethe, R.W.4    Correa, I.D.5    Prakash, S.R.6    Beck, K.D.7    Moore, L.B.8    Kliewer, S.A.9    Lehmann, J.M.10
  • 18
    • 0029102676 scopus 로고
    • Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: Alternative promoter use and different splicing yield two mPPAR gamma isoforms
    • Zhu, Y., Qi, C., Korenberg, J. R., Chen, X. N., Noya, D., Rao, M. S., Reddy, J. K. (1995) Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms. Proc. Natl. Acad. Sci. USA 92, 7921-7925.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7921-7925
    • Zhu, Y.1    Qi, C.2    Korenberg, J.R.3    Chen, X.N.4    Noya, D.5    Rao, M.S.6    Reddy, J.K.7
  • 21
    • 0030951143 scopus 로고    scopus 로고
    • Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPAR-gamma2 versus PPAR-gammal and activation with Retinoid X Receptor agonists and antagonists
    • Mukherjee, R., Jow, L., Croston, G. E., Paterniti, J. R., Jr. (1997) Identification, characterization, and tissue distribution of human Peroxisome Proliferator-Activated Receptor (PPAR) isoforms PPAR-gamma2 versus PPAR-gammal and activation with Retinoid X Receptor agonists and antagonists. J. Biol. Chem. 272, 8071-8076.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8071-8076
    • Mukherjee, R.1    Jow, L.2    Croston, G.E.3    Paterniti J.R., Jr.4
  • 22
    • 0030977450 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gene expression in human tissues: Effects of obesity, wieght loss, and regulation by insulin and glucocorticoids
    • Vidal-Puig, A. J., Considine, R. V., Jimenez-Liñan, M., Werman, A., Pories, W. J., Caro, J. F., Flier, J. S. (1997) Peroxisome proliferator-activated receptor gene expression in human tissues: Effects of obesity, wieght loss, and regulation by insulin and glucocorticoids. J. Clin. Invest. 99, 2416-2422.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2416-2422
    • Vidal-Puig, A.J.1    Considine, R.V.2    Jimenez-Liñan, M.3    Werman, A.4    Pories, W.J.5    Caro, J.F.6    Flier, J.S.7
  • 23
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
    • Ricole, M., Li, A. C., Willson, T. M., Kelly, C. J., Glass, C. K. (1998) The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 391, 79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricole, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 24
    • 0032582349 scopus 로고    scopus 로고
    • PPARγ3 mRNA: A distinct PPARγ mRNA subtype transcribed from an independent promoter
    • Fajas, L., Fruchart, J. C., Auwerx, J. (1998) PPARγ3 mRNA: a distinct PPARγ mRNA subtype transcribed from an independent promoter. FEBS Lett. 438, 55-60.
    • (1998) FEBS Lett. , vol.438 , pp. 55-60
    • Fajas, L.1    Fruchart, J.C.2    Auwerx, J.3
  • 25
    • 0032560545 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
    • Ricote, M., Huang, J., Fajas, L., Li, A., Welch, J., Najib, J., Witztum, J. L., Auwerx, J., Palinski, W., Glass, C. K. (1998) Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA 95, 7614-7619.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7614-7619
    • Ricote, M.1    Huang, J.2    Fajas, L.3    Li, A.4    Welch, J.5    Najib, J.6    Witztum, J.L.7    Auwerx, J.8    Palinski, W.9    Glass, C.K.10
  • 26
    • 0029152375 scopus 로고
    • Isolation of the human peroxisome proliferator activated receptor gamma cDNA: Expression in hematopoietic cells and chromosomal mapping
    • Greene, M. E., Blumberg, B., McBride, O. W., Yi, H. F., Kronquist, K., Kwan, K., Hsieh, L., Greene, G., Nimer, S. D. (1995) Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Expression 4, 281-299.
    • (1995) Gene Expression , vol.4 , pp. 281-299
    • Greene, M.E.1    Blumberg, B.2    McBride, O.W.3    Yi, H.F.4    Kronquist, K.5    Kwan, K.6    Hsieh, L.7    Greene, G.8    Nimer, S.D.9
  • 27
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang, C., Ting, A. T., Seed, B. (1998) PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391, 82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 29
    • 0031870652 scopus 로고    scopus 로고
    • Macrophages in human atheroma contain ppargamma: Differentiation-dependent peroxisomal proliferator-activated receptor gamma expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro
    • Marx, N., Sukhova, G., Murphy, C., Libby, P., Plulzky, J. (1998) Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro. Am. J. Pathol. 153, 17-23.
    • (1998) Am. J. Pathol. , vol.153 , pp. 17-23
    • Marx, N.1    Sukhova, G.2    Murphy, C.3    Libby, P.4    Plulzky, J.5
  • 30
    • 0032540012 scopus 로고    scopus 로고
    • PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz, P., Nagy, L., Alvarez, J. G. A., Thomazy, V. A., Evans, R. M. (1998) PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93, 241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.A.3    Thomazy, V.A.4    Evans, R.M.5
  • 32
    • 0030612740 scopus 로고    scopus 로고
    • PPARα induces cell cycle withdrawal: Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2a
    • Altiok, S., Xu, M., Spiegelman, B. M. (1997) PPARα induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev. 11, 1987-1998.
    • (1997) Genes Dev. , vol.11 , pp. 1987-1998
    • Altiok, S.1    Xu, M.2    Spiegelman, B.M.3
  • 33
    • 0032145363 scopus 로고    scopus 로고
    • Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo
    • Kubota, T., Koshizuka, K., Williamson, E. A., Asou, H., Said, J. W., Holden, S., Miyoshi, I., Koeffler, H. P. (1998) Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo. Cancer Res. 58, 3344-3352.
    • (1998) Cancer Res. , vol.58 , pp. 3344-3352
    • Kubota, T.1    Koshizuka, K.2    Williamson, E.A.3    Asou, H.4    Said, J.W.5    Holden, S.6    Miyoshi, I.7    Koeffler, H.P.8
  • 35
    • 0031844535 scopus 로고    scopus 로고
    • The nuclear eicosanoid receptor, pparγ, is aberrantly expressed in colonie cancers
    • DuBois, R. N., Gupta, R., Brockman, J., Reddy, B. S., Krakow, S. L., Lazar, M. A. (1998) The nuclear eicosanoid receptor, PPARγ, is aberrantly expressed in colonie cancers. Carcinogenesis 19, 49-53.
    • (1998) Carcinogenesis , vol.19 , pp. 49-53
    • Dubois, R.N.1    Gupta, R.2    Brockman, J.3    Reddy, B.S.4    Krakow, S.L.5    Lazar, M.A.6
  • 36
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR-gamma
    • Nagy, L., Tontonoz, P., Alvarez, J. G. A., Chen, H., Evans, R. M. (1998) Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR-gamma. Cell 93, 229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.A.3    Chen, H.4    Evans, R.M.5
  • 38
    • 0030985318 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
    • Krey, G., Braissant, O., L'Horset, F., Kalkhoven, E., Perroud, M., Parker, M. G., Wahli, W. (1997) Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol. Endocrinol. 11, 779-791.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 779-791
    • Krey, G.1    Braissant, O.2    L'Horset, F.3    Kalkhoven, E.4    Perroud, M.5    Parker, M.G.6    Wahli, W.7
  • 42
    • 0038776380 scopus 로고    scopus 로고
    • Inhibition of adipogenesis through map kinase-mediated phosphorylation of PPARγ
    • Hu, E., Kim, J. B., Sarraf, P., Spiegelman, B. M. (1996) Inhibition of adipogenesis through Map Kinase-mediated phosphorylation of PPARγ. Science 274, 2100-2103.
    • (1996) Science , vol.274 , pp. 2100-2103
    • Hu, E.1    Kim, J.B.2    Sarraf, P.3    Spiegelman, B.M.4
  • 43
    • 0029775642 scopus 로고    scopus 로고
    • Insulin- and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor γ
    • Zhang, B., Berfer, J., Zhou, G., Elbrech, A., Biswas, S., White-Carrington, S., Szalkowski, D., Moller, D. E. (1996) Insulin- and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor γ. J. Biol. Chem. 271, 31771-31774.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31771-31774
    • Zhang, B.1    Berfer, J.2    Zhou, G.3    Elbrech, A.4    Biswas, S.5    White-Carrington, S.6    Szalkowski, D.7    Moller, D.E.8
  • 44
    • 0031057517 scopus 로고    scopus 로고
    • Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
    • Adams, M., Reginato, M. J., Shao, D. S., Lazar, M. A., Chatterjee, V. K. (1997) Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J. Biol. Chem. 272, 5128-5132.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5128-5132
    • Adams, M.1    Reginato, M.J.2    Shao, D.S.3    Lazar, M.A.4    Chatterjee, V.K.5
  • 45
    • 0030964085 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor γ activity by mitogen-activated protein kinase
    • Camp, H. S., Tafuri, S. R. (1997) Regulation of peroxisome proliferator-activated receptor γ activity by mitogen-activated protein kinase. J. Biol. Chem. 272, 10811-10816.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10811-10816
    • Camp, H.S.1    Tafuri, S.R.2
  • 47
    • 1842295133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators and compressors
    • DiRenzo, J., Söderström, M., Kurokawa, R., Ogliastro, M.-H., Ricote, M., Ingrey, S., Hörlein, A., Rosenfeld, M. G., Glass, C. K. (1997) Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators and compressors. Mol. Cell. Biol. 17, 2166-2176.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2166-2176
    • Direnzo, J.1    Söderström, M.2    Kurokawa, R.3    Ogliastro, M.-H.4    Ricote, M.5    Ingrey, S.6    Hörlein, A.7    Rosenfeld, M.G.8    Glass, C.K.9
  • 48
    • 0030771856 scopus 로고    scopus 로고
    • Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor
    • Zhu, Y., Qi, C., Jain, S., Rao, M. S., Reddy, J. K. (1997) Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor. J. Biol. Chem. 272, 25500-25506.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25500-25506
    • Zhu, Y.1    Qi, C.2    Jain, S.3    Rao, M.S.4    Reddy, J.K.5
  • 49
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., Spiegelman, B. M. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829-839.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 50
    • 0033583023 scopus 로고    scopus 로고
    • P300 interacts with the N- and C-terminal part of PPARγ2 in a ligand-independent and -dependent manner, respectively
    • Gelman, L., Zhou, G., Fajas, L., Raspe, E., Fruchart, J.-C., Auwerx, J. (1999) p300 interacts with the N- and C-terminal part of PPARγ2 in a ligand-independent and -dependent manner, respectively. J. Biol. Chem. 274, 7681-7688.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7681-7688
    • Gelman, L.1    Zhou, G.2    Fajas, L.3    Raspe, E.4    Fruchart, J.-C.5    Auwerx, J.6
  • 52
    • 0030570961 scopus 로고    scopus 로고
    • A growing coactivator network
    • Janknecht, R., Hunter, T. (1996) A growing coactivator network. Nature 383, 22-23.
    • (1996) Nature , vol.383 , pp. 22-23
    • Janknecht, R.1    Hunter, T.2
  • 54
    • 0030912539 scopus 로고    scopus 로고
    • The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function
    • Torchia, J., Rose, D. W., Inostroza, J., Kamei, Y., Westin, S., Glass, C. K., Rosenfeld, M. G. (1997) The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature 387, 677-684.
    • (1997) Nature , vol.387 , pp. 677-684
    • Torchia, J.1    Rose, D.W.2    Inostroza, J.3    Kamei, Y.4    Westin, S.5    Glass, C.K.6    Rosenfeld, M.G.7
  • 55
    • 0030916336 scopus 로고    scopus 로고
    • What's up and down with histone deacetylation and transcription?
    • Pazin, M. J., Kadonaga, J. T. (1997) What's up and down with histone deacetylation and transcription? Cell 89, 325-328.
    • (1997) Cell , vol.89 , pp. 325-328
    • Pazin, M.J.1    Kadonaga, J.T.2
  • 56
    • 0030606239 scopus 로고    scopus 로고
    • The transcriptional coactivators p300 and CBP are histone acetyltransferases
    • Ogryzko, V. V., Schiltz, R. L., Russanova, V., Howard, B. H., Nakatani, Y. (1996) The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87, 953-959.
    • (1996) Cell , vol.87 , pp. 953-959
    • Ogryzko, V.V.1    Schiltz, R.L.2    Russanova, V.3    Howard, B.H.4    Nakatani, Y.5
  • 59
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs
    • Lehmann, J. M., Lenhard, J. M., Oliver, B. B., Ringhold, G. M., Kliewer, S. A. (1997) Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J. Biol. Chem. 272, 3406-3410.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringhold, G.M.4    Kliewer, S.A.5
  • 60
    • 0032528350 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase by peroxisome proliferator-activated receptor agonists: Correlation with induction of heme oxygenase I
    • Colville-Nash, P. R., Qureshi, S. S., Willis, D., Willoughby, D. A. (1998) Inhibition of inducible nitric oxide synthase by peroxisome proliferator-activated receptor agonists: correlation with induction of heme oxygenase I. J. Immunol. 161, 978-984.
    • (1998) J. Immunol. , vol.161 , pp. 978-984
    • Colville-Nash, P.R.1    Qureshi, S.S.2    Willis, D.3    Willoughby, D.A.4
  • 61
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross, R. (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362, 801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 62
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • Ross, R. (1999) Atherosclerosis - an inflammatory disease. N. Engl. J. Med 340, 115-126.
    • (1999) N. Engl. J. Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 63
    • 0029838564 scopus 로고    scopus 로고
    • Inflammatory and immunological nature of atherosclerosis
    • Watanabe, T., Haraoka, S., Shimokama, T. (1996) Inflammatory and immunological nature of atherosclerosis. Int. J. Cardiol. 54, S51-S60.
    • (1996) Int. J. Cardiol. , vol.54
    • Watanabe, T.1    Haraoka, S.2    Shimokama, T.3
  • 64
    • 0028875797 scopus 로고
    • Immunological mechanisms in atherosclerosis
    • Yokota, T., Hansson, G. K. (1995) Immunological mechanisms in atherosclerosis. J. Int. Med. 238, 479-189.
    • (1995) J. Int. Med. , vol.238 , pp. 479-1189
    • Yokota, T.1    Hansson, G.K.2
  • 65
    • 0026082959 scopus 로고
    • Involvement of the immune system in human atherogenesis: Current knowledge and unanswered questions
    • Libby, P., Hansson, G. K. (1991) Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab. Invest. 64, 5-15.
    • (1991) Lab. Invest. , vol.64 , pp. 5-15
    • Libby, P.1    Hansson, G.K.2
  • 66
    • 0028173897 scopus 로고
    • Structures and functions of multiligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein (LRP)
    • Krieger, M., Herz, J. (1994) Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). Annu. Rev. Biochem. 63, 601-637.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 601-637
    • Krieger, M.1    Herz, J.2
  • 67
    • 0024603895 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberg, D., Parthasarathy, S., Carew, T. E., Khoo, J. C., Witztum, J. L. (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320, 915-924.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 68
    • 0029053557 scopus 로고
    • T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein
    • Stemme, S., Faber, B., Holm, J., Wiklund, O., Witztum, J., Hansson, G. K. (1995) T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA 92, 3893-3897.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3893-3897
    • Stemme, S.1    Faber, B.2    Holm, J.3    Wiklund, O.4    Witztum, J.5    Hansson, G.K.6
  • 72
    • 0027240176 scopus 로고
    • Cloning of a rat adipocyte membrane protein implicated in binding or transport of long chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36
    • Abumrad, N. A., el-Maghrabi, M. R., Amri, E. Z., Lopez, E., Grimaldi, P. A. (1993) Cloning of a rat adipocyte membrane protein implicated in binding or transport of long chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36. J. Biol. Chem. 268, 17665-17668.
    • (1993) J. Biol. Chem. , vol.268 , pp. 17665-17668
    • Abumrad, N.A.1    El-Maghrabi, M.R.2    Amri, E.Z.3    Lopez, E.4    Grimaldi, P.A.5
  • 73
    • 0344333464 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells
    • Marx, N., Scheonbeck, U., Lazar, M. A., Libby, P., Plutzky, J. (1998) Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ. Res. 83, 1097-1103.
    • (1998) Circ. Res. , vol.83 , pp. 1097-1103
    • Marx, N.1    Scheonbeck, U.2    Lazar, M.A.3    Libby, P.4    Plutzky, J.5
  • 76
    • 0031750208 scopus 로고    scopus 로고
    • Effects of troglitazone and pioglitazone on cytokine-mediated endothelial cell proliferation in vitro
    • Gralinski, M. R., Rowse, P. E., Breider, M. A. (1998) Effects of troglitazone and pioglitazone on cytokine-mediated endothelial cell proliferation in vitro. J. Cardiovasc. Pharmacol. 31, 909-913.
    • (1998) J. Cardiovasc. Pharmacol. , vol.31 , pp. 909-913
    • Gralinski, M.R.1    Rowse, P.E.2    Breider, M.A.3
  • 77
    • 0033605677 scopus 로고    scopus 로고
    • Peroxisome proliferalor-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo
    • Xin, X., Yang, S., Kowalski, J., Gerritsen, M. E. (1999) Peroxisome proliferalor-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo. J. Biol. Chem. 274, 9116-9121.
    • (1999) J. Biol. Chem. , vol.274 , pp. 9116-9121
    • Xin, X.1    Yang, S.2    Kowalski, J.3    Gerritsen, M.E.4
  • 81
  • 84
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human brest cancer cells in vitro and in BNX mice
    • Elstner, E., Muller, C., Koshizuka, K., Williamson, E. A., Park, D., Asou, H., Shintaku, P., Said, J. W., Heber, D., Koeffler, P. (1998) Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human brest cancer cells in vitro and in BNX mice. Proc. Natl. Acad. Sci. USA 95, 8806-8811.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8806-8811
    • Elstner, E.1    Muller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6    Shintaku, P.7    Said, J.W.8    Heber, D.9    Koeffler, P.10


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