Degradation of the peroxisome proliferator-activated receptor γ is linked to ligand-dependent activation

Journal of Biological Chemistry

Volumn 275, Issue 24, 2000, Pages 18527-18533

  Hauser, Stefanie ^a   Adelmant, Guillaume ^a   Sarraf, Pasha ^a   Wright, Harold M ^a   Mueller, Elisabetta ^a   Spiegelman, Bruce M ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR;

ADIPOSE TISSUE CELL; ARTICLE; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS INHIBITION; TRANSCRIPTION REGULATION;

3T3 CELLS; ADIPOCYTES; ANIMALS; CYSTEINE ENDOPEPTIDASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LIGANDS; MICE; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0034674567     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M001297200     Document Type: Article

References (40)

1. Wu, Z., Puigserver, P., and Spiegelman, B. M. (1999) Curr. Opin. Cell Biol. 11, 689-694
2. Tontonoz, P., Hu, E., and Spiegelman, B. M. (1994) Cell 79, 1147-1156
3. Kubota, N., Terauchi, Y., Miki, H., Tamemoto, H., Yamauchi, T., Komeda, K., Satoh, S., Nakano, R., Ishii, C., Sugiyama, T., Eto, K., Tsubamoto, Y., Okuno, A., Murakami, K., Sekihara, H., Hasegawa, G., Naito, M., Toyoshima, Y., Tanaka, S., Shiota, K., Kitamura, T., Fujita, T., Ezaki, O., Aizawa, S., Nagai, R., Tobe, K., Kimura, S., and Kadowaki, T. (1999) Mol. Cell 4, 597-609
4. Barak, Y., Nelson, M. C., Ong, E. S., Jones, Y. Z., Ruiz-Lozano, P., Chien, K. R., Koder, A., and Evans, R. M. (1999) Mol. Cell 4, 585-595
5. Rosen, E. D., Sarraf, P., Troy, A. E., Bradwin, G., Moore, K., Milstone, D. S., Spiegelman, B. M., and Mortensen, R. M. (1999) Mol. Cell 4, 611-617
6. Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., and Kliewer, S. A. (1995) J. Biol. Chem. 270, 12953-12956
7. Henry, R. R. (1997) Endocrinol. Metab. Clin. North Am. 26, 553-573
8. Barroso, I., Gurnell, M., Crowley, V. E., Agostini, M., Schwabe, J. W., Soos, M. A., Maslen, G. L., Williams, T. D., Lewis, H., Schafer, A. J., Chatterjee, V. K., and O'Rahilly, S. (1999) Nature 402, 880-883
9. Ricote, M., Huang, J. T., Welch, J. S., and Glass, C. K. (1999) J. Leukoc. Biol. 66, 733-739
10. Rocchi, S., and Auwerx, J. (1999) Ann. Med. 31, 342-351
11. Sarraf, P., Mueller, E., Smith, W. M., Wright, H. M., Kum, J. B., Aaltonen, L. A., de la Chapelle, A., Spiegelman, B. M., and Eng, C. (1999) Mol. Cell 3, 799-804
12. Demetri, G. D., Fletcher, C. D., Mueller, E., Sarraf, P., Naujoks, R., Campbell, N., Spiegelman, B. M., and Singer, S. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3951-3956
13. Lehmann, J. M., Lenhard, J. M., Oliver, B. B., Ringold, G. M., and Kliewer, S. A. (1997) J. Biol. Chem. 272, 3406-3410
14. Nagy, L., Tontonoz, P., Alvarez, J. G., Chen, H., and Evans, R. M. (1998) Cell 93, 229-240
15. Kliewer, S. A., Lenhard, J. M., Willson, T. M., Patel, I., Morris, D. C., and Lehmann, J. M. (1995) Cell 83, 813-819
16. Forman, B. M., Tontonoz, P., Chen, J., Brun, R. P., Spiegelman, B. M., and Evans, R. M. (1995) Cell 83, 803-812
17. Huang, J. T., Welch, J. S., Ricote, M., Binder, C. J., Willson, T. M., Kelly, C., Witztom, J. L., Funk, C. D., Conrad, D., and Glass, C. K. (1999) Nature 400, 378-382
18. Camp, H. S., and Tafuri, S. R. (1997) J. Biol. Chem. 272, 10811-10816
19. Hu, E., Kim, J. B., Sarraf, P., and Spiegelman, B. M. (1996) Science 274, 2100-2103
20. Zhang, B., Berger, J., Zhou, G., Elbrecht, A., Biswas, S., White-Carrington, S., Szalkowski, D., and Moller, D. E. (1996) J. Biol. Chem. 271, 31771-31774
21. Zhou, Y.-C., and Waxman, D. J. (1999) J. Biol. Chem. 274, 2672-2681
22. Nolte, R. T., Wisely, G. B., Westin, S., Cobb, J. E., Lambert, M. H., Kurokawa, R., Rosenfeld, M. G., Willson, T. M., Glass, C. K., and Milburn, M. V. (1998) Nature 395, 137-143
23. McKenna, N. J., Xu, J., Nawaz, Z., Tsai, S. Y., Tsai, M. J., and O'Malley, B. W. (1999) J. Steroid Biochem. Mol. Biol. 69, 3-12
24. Shao, D., Rangwala, S. M., Bailey, S. T., Krakow, S. L., Reginato, M. J., and Lazar, M. A. (1998) Nature 396, 377-380
25. Green, H., and Kehinde, O. (1974) Cell 1, 113-116
26. Willson, T. M., Cobb, J. E., Cowan, D. J., Wiethe, R. W., Correa, I. D., Prakash, S. R., Beck, K. D., Moore, L. B., Kliewer, S. A., and Lehmann, J. M. (1996) J. Med. Chem. 39, 665-668
27. Rosenbaum, S. E., and Greenberg, A. S. (1998) Mol. Endocrinol. 12, 1150-1160
28. Camp, H. S., Whitton, A. L., and Tafuri, S. R. (1999) FEBS Lett. 447, 186-190
29. Ciechanover, A. (1998) EMBO J. 17, 7151-7160
30. Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., and Goldberg, A. L. (1994) Cell 78, 761-771
31. Laney, J. D., and Hochstrasser, M. (1999) Cell 97, 427-430
32. Strous, G. J., and Govers, R. (1999) J. Cell Sci. 112(Pt 10), 1417-1423
33. Chen, H.. Lin, R. J., Xie, W., Wilpitz, D., and Evans, R. M. (1999) Cell 98, 675-686
34. Syvala, H., Vienonen, A., Zhuang, Y. H., Kivineva, M., Ylikomi, T., and Tuohimaa, P. (1998) Life Sci. 63, 1505-1512
35. Zhu, J., Gianni, M., Kopf, E., Honore, N., Chelbi-Alix, M., Koken, M., Quignon, F., Rochette-Egly, C., and de The, H. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14807-14812
36. Alarid, E. T., Bakopoulos, N., and Solodin, N. (1999) Mol. Endocrinol. 13, 1522-1534
37. El Khissiin, A., and Leclercq, G. (1999) FEBS Lett. 448, 160-166
38. Nawaz, Z., Lonard, D. M., Dennis, A. P., Smith, C. L., and O'Malley, B. W. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1858-1862
39. Hu, X., and Lazar, M. A. (1999) Nature 402, 93-96
40. Grossman, S. R., Perez, M., Kung, A. L., Joseph, M., Mansur, C., Xiao, Z. X., Kumar, S., Howley, P. M., and Livingston, D. M. (1998) Mol. Cell 2, 405-415