-
1
-
-
0018764335
-
Diabetes and cardiovascular disease: The Framingham study
-
Kannel, W., and McGee, D. 1979. Diabetes and cardiovascular disease: the Framingham study. JAMA. 241:2035-2038.
-
(1979)
JAMA
, vol.241
, pp. 2035-2038
-
-
Kannel, W.1
McGee, D.2
-
2
-
-
0025361904
-
5-year incidence of atherosclerotic vascular disease in relation to general risk factors, insulin levels, and abnormalities in lipoprotein composition in non-insulin-dependent diabetic and nondiabetic subjects
-
Uusitupa, M., Niskanen, L., and Siitonen, O. 1990. 5-year incidence of atherosclerotic vascular disease in relation to general risk factors, insulin levels, and abnormalities in lipoprotein composition in non-insulin-dependent diabetic and nondiabetic subjects. Circulation. 82:27-36.
-
(1990)
Circulation
, vol.82
, pp. 27-36
-
-
Uusitupa, M.1
Niskanen, L.2
Siitonen, O.3
-
3
-
-
0024603895
-
Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
-
Steinberg, D., Parthasarathy, S., Carew, T.E., Khoo, J.C., and Witztum, J.L. 1989. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320:915-924.
-
(1989)
N. Engl. J. Med.
, vol.320
, pp. 915-924
-
-
Steinberg, D.1
Parthasarathy, S.2
Carew, T.E.3
Khoo, J.C.4
Witztum, J.L.5
-
4
-
-
0031456505
-
Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions
-
Napoli, C., et al. 1997. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J. Clin. Invest. 100:2680-2690.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2680-2690
-
-
Napoli, C.1
-
5
-
-
0009720857
-
Purification and characterization of a bovine acetyl low density lipoprotein receptor
-
Kodama, T., Reddy, P., Kishimoto, C., and Krieger, M. 1988. Purification and characterization of a bovine acetyl low density lipoprotein receptor. Proc. Natl. Acad. Sci. USA. 85:9238-9242.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 9238-9242
-
-
Kodama, T.1
Reddy, P.2
Kishimoto, C.3
Krieger, M.4
-
6
-
-
0027280397
-
CD36 is a receptor for oxidized low density lipoprotein
-
Endemann, G., et al. 1993. CD36 is a receptor for oxidized low density lipoprotein. J. Biol. Chem. 268:11811-11816.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11811-11816
-
-
Endemann, G.1
-
7
-
-
0029966853
-
Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein
-
Ramprasad, M.P., Terpstra, V., Kondratenko, N., Quehenberger, O., and Steinberg, D. 1996. Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA. 93:14833-14838.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14833-14838
-
-
Ramprasad, M.P.1
Terpstra, V.2
Kondratenko, N.3
Quehenberger, O.4
Steinberg, D.5
-
8
-
-
0022591979
-
The pathogenesis of atherosclerosis
-
Ross, R. 1986. The pathogenesis of atherosclerosis. N. Engl. J. Med. 314:488-500.
-
(1986)
N. Engl. J. Med.
, vol.314
, pp. 488-500
-
-
Ross, R.1
-
9
-
-
0033552883
-
Atherosclerosis: An inflammatory disease
-
Ross, R. 1999. Atherosclerosis: an inflammatory disease. N. Engl. J. Med. 340:115-126.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
10
-
-
0032572719
-
Decreased lesion formation in CCR2-/-mice reveals a role for chemokines in the initiation of atherosclerosis
-
Boring, L., Gosling, J., Cleary, M., and Charo, I.F. 1998. Decreased lesion formation in CCR2-/-mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 394:894-897.
-
(1998)
Nature
, vol.394
, pp. 894-897
-
-
Boring, L.1
Gosling, J.2
Cleary, M.3
Charo, I.F.4
-
11
-
-
0033559691
-
MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B
-
Gosling, J., et al. 1999. MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J. Clin. Invest. 103:773-778.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 773-778
-
-
Gosling, J.1
-
12
-
-
0030895048
-
A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection
-
Suzuki, H., et al. 1997. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature. 386:292-296.
-
(1997)
Nature
, vol.386
, pp. 292-296
-
-
Suzuki, H.1
-
13
-
-
0034101821
-
Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice
-
Febraio, M., et al. 2000. Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. J. Clin. Invest. 105:1049-1056.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1049-1056
-
-
Febraio, M.1
-
14
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes, P.J., and Karin, M. 1997. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336:1066-1071.
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
15
-
-
0027438302
-
v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines
-
Sato, H., Kita, M., and Seiki, M. 1993. v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines. J. Biol. Chem. 268:23460-23468.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 23460-23468
-
-
Sato, H.1
Kita, M.2
Seiki, M.3
-
16
-
-
0032560545
-
Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
-
Ricote, M., et al. 1998. Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA. 95:7614-7619.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7614-7619
-
-
Ricote, M.1
-
17
-
-
0031870652
-
Macrophages in human atheroma contain PPARgamma: Differentiation-dependent peroxisomal proliferator-activated receptor gamma expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro
-
Marx, N., Sukhova, G., Murphy, C., Libby, P., and Plutzky, J. 1998. Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro. Am. J. Pathol. 153:17-23.
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 17-23
-
-
Marx, N.1
Sukhova, G.2
Murphy, C.3
Libby, P.4
Plutzky, J.5
-
18
-
-
0032847680
-
Peroxisome proliferator-activared receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction
-
Jackson, S.M., et al. 1999. Peroxisome proliferator-activared receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. Arterioscler. Thromb. Vasc. Biol. 19:2094-2104.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 2094-2104
-
-
Jackson, S.M.1
-
19
-
-
0032540012
-
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz, P., Nagy, L., Alvarez, J.G.A., Thomazy, V.A., and Evans, R.M. 1998. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93:241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.A.3
Thomazy, V.A.4
Evans, R.M.5
-
20
-
-
0034711678
-
Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
-
Pasceri, V., Wu, H.D., Willerson, J.T. and Yeh, E.T. 2000. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation. 101:235-238.
-
(2000)
Circulation
, vol.101
, pp. 235-238
-
-
Pasceri, V.1
Wu, H.D.2
Willerson, J.T.3
Yeh, E.T.4
-
21
-
-
0032540325
-
Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR-gamma
-
Nagy, L., Tontonoz, P., Alvarez, J.G.A., Chen, H., and Evans, R.M. 1998. Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR-gamma. Cell. 91:229-240.
-
(1998)
Cell
, vol.91
, pp. 229-240
-
-
Nagy, L.1
Tontonoz, P.2
Alvarez, J.G.A.3
Chen, H.4
Evans, R.M.5
-
22
-
-
0028972025
-
2 is a ligand for the adipocyte determination factor PPARγ
-
2 is a ligand for the adipocyte determination factor PPARγ. Cell. 83:803-812.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
-
23
-
-
0006132932
-
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
-
Kliewer, S.A., et al. 1997. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ. Proc. Natl. Acad. Sci. USA. 94:4318-4323.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4318-4323
-
-
Kliewer, S.A.1
-
24
-
-
0033213637
-
PPARγ is required for placental, cardiac, and adipose tissue development
-
Barak, Y., et al. 1999. PPARγ is required for placental, cardiac, and adipose tissue development. Mol. Cell. 4:585-595.
-
(1999)
Mol. Cell.
, vol.4
, pp. 585-595
-
-
Barak, Y.1
-
25
-
-
0033212964
-
PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota, N., et al. 1999. PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol. Cell. 4:597-609.
-
(1999)
Mol. Cell.
, vol.4
, pp. 597-609
-
-
Kubota, N.1
-
26
-
-
0033213631
-
PPARγ is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen, E.D., et al. 1999. PPARγ is required for the differentiation of adipose tissue in vivo and in vitro. Mol. Cell. 4:611-617.
-
(1999)
Mol. Cell.
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
-
27
-
-
0027983920
-
Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
-
Nolan, J.J., Ludvik, B., Beerdsen, P., Joyce, M., and Olefsky, J. 1994. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N. Engl. J Med. 331:1188-1193.
-
(1994)
N. Engl. J Med.
, vol.331
, pp. 1188-1193
-
-
Nolan, J.J.1
Ludvik, B.2
Beerdsen, P.3
Joyce, M.4
Olefsky, J.5
-
28
-
-
0031888958
-
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
-
Jiang, C., Ting, A.T., and Seed, B. 1998. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature. 391:82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
29
-
-
0031886864
-
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
-
Ricote, M., Li, A.C., Willson, T.M., Kelly, C.J., and Glass, C.K. 1998. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature. 391:79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
30
-
-
0032746173
-
A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response
-
Su, C.G., et al. 1999. A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response. J. Clin. Invest. 104:383-389.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 383-389
-
-
Su, C.G.1
-
31
-
-
0003900967
-
-
C.V. Mosby Co., St. Louis, Missouri, USA. 481 pp
-
Sheehan, D.C., and Hrapchak, B.B. 1980. Theory and practice of histotechnology. C.V. Mosby Co., St. Louis, Missouri, USA. 481 pp.
-
(1980)
Theory and Practice of Histotechnology
-
-
Sheehan, D.C.1
Hrapchak, B.B.2
-
32
-
-
0028862192
-
Quantitation of atherosclerosis in murine models: Correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apoprotein E-deficient mice
-
Tangirala, R.K., Rubin, E.M., and Palinski, W. 1995. Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apoprotein E-deficient mice. J. Lipid Res. 36:1-9.
-
(1995)
J. Lipid Res.
, vol.36
, pp. 1-9
-
-
Tangirala, R.K.1
Rubin, E.M.2
Palinski, W.3
-
33
-
-
0033998334
-
The PPARs: From orphan receptors to drug discovery
-
Willson, T., Brown, P., Sternbach, D., and Henke, B. 2000. The PPARs: from orphan receptors to drug discovery. J. Med. Chem. 43:527-550.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 527-550
-
-
Willson, T.1
Brown, P.2
Sternbach, D.3
Henke, B.4
-
34
-
-
0030797134
-
Effect of probucol treatment on gene expression of VCAM-1, MCP-1 and M-CSF in the aortic wall of LDL receptor-deficient rabbits during early atherogenesis
-
Fruebis, J., Gonzales, V., Silvestre, M., and Palinski, W. 1997. Effect of probucol treatment on gene expression of VCAM-1, MCP-1 and M-CSF in the aortic wall of LDL receptor-deficient rabbits during early atherogenesis. Arterioscler. Thromb. Vasc. Biol. 17:1289-1302.
-
(1997)
Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 1289-1302
-
-
Fruebis, J.1
Gonzales, V.2
Silvestre, M.3
Palinski, W.4
-
35
-
-
0034019934
-
In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression
-
Tsimikas, S., Shortal, B.P., Witztum, J.L., and Palinski, W. 2000. In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression. Arterioscler. Thromb. Vasc. Biol. 20:689-697.
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
, pp. 689-697
-
-
Tsimikas, S.1
Shortal, B.P.2
Witztum, J.L.3
Palinski, W.4
-
36
-
-
0027474061
-
Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins
-
Holness, C.L., and Simmons, D.L. 1993. Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins. Blood. 81:1607-1613.
-
(1993)
Blood
, vol.81
, pp. 1607-1613
-
-
Holness, C.L.1
Simmons, D.L.2
-
37
-
-
0032890834
-
PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells
-
Goetze, S., et al. 1999. PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells. J. Cardiovasc. Pharmacol. 33:798-806.
-
(1999)
J. Cardiovasc. Pharmacol.
, vol.33
, pp. 798-806
-
-
Goetze, S.1
-
38
-
-
0029549156
-
Cytokines regulate vascular functions related to stability of the atherosclerotic plaque
-
Libby, P., Sukhova, G., Lee, R.T., and Galis, Z.S. 1995. Cytokines regulate vascular functions related to stability of the atherosclerotic plaque. J. Cardiovasc. Pharmacol. 25(Suppl. 2):S9-S12.
-
(1995)
J. Cardiovasc. Pharmacol.
, vol.25
, Issue.2 SUPPL.
-
-
Libby, P.1
Sukhova, G.2
Lee, R.T.3
Galis, Z.S.4
-
39
-
-
0032988209
-
Thiazolidinedione inhibits the production of monocyte chemoattractant protein-1 in cytokine-treated human vascular endothelial cells
-
Murao, K., et al. 1999. Thiazolidinedione inhibits the production of monocyte chemoattractant protein-1 in cytokine-treated human vascular endothelial cells. FEBS Lett. 454:27-30.
-
(1999)
FEBS Lett.
, vol.454
, pp. 27-30
-
-
Murao, K.1
-
40
-
-
0029861097
-
Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia
-
Law, R.E., et al. 1996. Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia. J. Clin. Invest. 98:1897-1905.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1897-1905
-
-
Law, R.E.1
-
41
-
-
0032565868
-
Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators
-
Staels, B., et al. 1998. Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators. Nature. 393:790-793.
-
(1998)
Nature
, vol.393
, pp. 790-793
-
-
Staels, B.1
-
42
-
-
0032936073
-
Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet
-
Merat, S., Casanada, F., Sutphin, M., Palinski, W., and Reaven, P.D. 1999. Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet. Arterioscler. Thromb. Vasc. Biol. 19:1223-1230.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 1223-1230
-
-
Merat, S.1
Casanada, F.2
Sutphin, M.3
Palinski, W.4
Reaven, P.D.5
-
43
-
-
0033628745
-
Selective estrogen receptor modulators and postmenopausal health
-
Roe, E.B., Chiu, K.M., and Arnaud, C.D. 2000. Selective estrogen receptor modulators and postmenopausal health. Adv. Intern. Med. 45:257-278.
-
(2000)
Adv. Intern. Med.
, vol.45
, pp. 257-278
-
-
Roe, E.B.1
Chiu, K.M.2
Arnaud, C.D.3
|