-
1
-
-
0842308887
-
European Union meets the challenge of the growing importance of allergy and asthma in Europe
-
Bousquet J, Ansotegui IJ, Van Ree R, Burney PG, Zuberbier T, van Cauwenberge P. European Union meets the challenge of the growing importance of allergy and asthma In Europe. Allergy 2004;59:1-4.
-
(2004)
Allergy
, vol.59
, pp. 1-4
-
-
Bousquet, J.1
Ansotegui, I.J.2
Van Ree, R.3
Burney, P.G.4
Zuberbier, T.5
Van Cauwenberge, P.6
-
2
-
-
0031015314
-
Asthma: An epidemic in the absence of infection
-
Cookson W, Moffatt M. Asthma: an epidemic in the absence of infection. Science 1997;275:41-2.
-
(1997)
Science
, vol.275
, pp. 41-42
-
-
Cookson, W.1
Moffatt, M.2
-
4
-
-
0028213032
-
Increase in asthma: A more toxic environment or a more susceptible population?
-
Seaton A, Godden DJ, Brown K. Increase in asthma: a more toxic environment or a more susceptible population? Thorax 1994;49:171-4.
-
(1994)
Thorax
, vol.49
, pp. 171-174
-
-
Seaton, A.1
Godden, D.J.2
Brown, K.3
-
5
-
-
0037320195
-
Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease
-
Fabbri L, Romagnoli M, Corbetta L, Casoni G, Busljetic K, Turato G, et al. Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003;167:418-24.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 418-424
-
-
Fabbri, L.1
Romagnoli, M.2
Corbetta, L.3
Casoni, G.4
Busljetic, K.5
Turato, G.6
-
7
-
-
0028353492
-
The TNF receptor super-family of cellular and viral proteins: Activation, costimulation, and death
-
Smith CA, Farrah T, Goodwin RG. The TNF receptor super-family of cellular and viral proteins: activation, costimulation, and death. Cell 1994;76:959-62.
-
(1994)
Cell
, vol.76
, pp. 959-962
-
-
Smith, C.A.1
Farrah, T.2
Goodwin, R.G.3
-
8
-
-
1542390447
-
Control of the expression of inflammatory response genes
-
Saklatvala J, Dean J, Clark A. Control of the expression of inflammatory response genes. Biochem Soc Symp 2003;70: 95-106.
-
(2003)
Biochem Soc Symp
, vol.70
, pp. 95-106
-
-
Saklatvala, J.1
Dean, J.2
Clark, A.3
-
9
-
-
0642283970
-
Regulation of proliferation, survival and apoptosis by members of the TNF superfamily
-
Gaur U, Aggarwal BB. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem Pharmacol 2003;66:1403-8.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 1403-1408
-
-
Gaur, U.1
Aggarwal, B.B.2
-
10
-
-
0033650501
-
Lnterleukin-1 family: From genes to human disease
-
Laurincova B. lnterleukin-1 family: from genes to human disease. Acta Univ Palacki Olomuc Foe Med 2000;143:1929.
-
(2000)
Acta Univ Palacki Olomuc Foe Med
, vol.143
, pp. 1929
-
-
Laurincova, B.1
-
12
-
-
0031172781
-
The Th1/Th2 paradigm
-
Romagnani S. The Th1/Th2 paradigm. Immunol Today 1997;18:263-6.
-
(1997)
Immunol Today
, vol.18
, pp. 263-266
-
-
Romagnani, S.1
-
13
-
-
0037314229
-
New insights into the pathogenesis of asthma
-
Elias JA, Lee CG, Zheng T, Ma B, Homer RJ, Zhu Z. New insights into the pathogenesis of asthma. J Clin Invest 2003;111:291-7.
-
(2003)
J Clin Invest
, vol.111
, pp. 291-297
-
-
Elias, J.A.1
Lee, C.G.2
Zheng, T.3
Ma, B.4
Homer, R.J.5
Zhu, Z.6
-
14
-
-
0031058726
-
Interleukin (IL)-6 directs the differentiation of IL-4producing CD4+ T cells
-
Rincon M, Anguita J, Nakamura T, Fikrig E, Flavell RA. Interleukin (IL)-6 directs the differentiation of IL-4producing CD4+ T cells. J Exp Med 1997;185:461-9.
-
(1997)
J Exp Med
, vol.185
, pp. 461-469
-
-
Rincon, M.1
Anguita, J.2
Nakamura, T.3
Fikrig, E.4
Flavell, R.A.5
-
15
-
-
0031179646
-
IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells
-
Kalinski P, Hilkens CM, Snijders A, Snijdewint FG, Kapsenberg ML. IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. Immunol 1997;159:28-35.
-
(1997)
Immunol
, vol.159
, pp. 28-35
-
-
Kalinski, P.1
Hilkens, C.M.2
Snijders, A.3
Snijdewint, F.G.4
Kapsenberg, M.L.5
-
16
-
-
0034046605
-
STAT family of transcription factors in cytokine-mediated biological responses
-
Takeda K, Akira S. STAT family of transcription factors in cytokine-mediated biological responses. Cytokine Growth Factor Rev 2000;11:199-207.
-
(2000)
Cytokine Growth Factor Rev
, vol.11
, pp. 199-207
-
-
Takeda, K.1
Akira, S.2
-
17
-
-
0028943484
-
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
-
Jacobson NG, Szabo SJ, Weber-Nordt RM, Zhong Z, Schreiber RD, Darnell Jr. JE, et al. Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med 1995;181:1755-62.
-
(1995)
J Exp Med
, vol.181
, pp. 1755-1762
-
-
Jacobson, N.G.1
Szabo, S.J.2
Weber-Nordt, R.M.3
Zhong, Z.4
Schreiber, R.D.5
Darnell Jr., J.E.6
-
18
-
-
0032555904
-
A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells
-
Kaplan MH, Wurster AL, GrusbyMJ. A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells. J Exp Med 1998:188:1191-6.
-
(1998)
J Exp Med
, vol.188
, pp. 1191-1196
-
-
Kaplan, M.H.1
Wurster, A.L.2
Grusby, M.J.3
-
19
-
-
0027972046
-
An interleukin-4-induced transcription factor: IL-4Stat
-
Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, McK-night SL. An interleukin-4-induced transcription factor: IL-4Stat. Science 1994;265:1701-6.
-
(1994)
Science
, vol.265
, pp. 1701-1706
-
-
Hou, J.1
Schindler, U.2
Henzel, W.J.3
Ho, T.C.4
Brasseur, M.5
McK-Night, S.L.6
-
20
-
-
0030949167
-
STAT6: Its role in interleukin 4-mediated biological functions
-
Takeda K, Kishimoto T, Akira S. STAT6: its role in interleukin 4-mediated biological functions. J Mot Med 1997;75: 317-26.
-
(1997)
J Mot Med
, vol.75
, pp. 317-326
-
-
Takeda, K.1
Kishimoto, T.2
Akira, S.3
-
21
-
-
9744278996
-
IL-17 cytokine family
-
Kawaguchi M, Adachi M, Oda N, Kokubu F, Huang SK. IL-17 cytokine family. J Allergy Clin Immunol 2004; 114: 1265-74.
-
(2004)
J Allergy Clin Immunol
, vol.114
, pp. 1265-1274
-
-
Kawaguchi, M.1
Adachi, M.2
Oda, N.3
Kokubu, F.4
Huang, S.K.5
-
22
-
-
0036785392
-
Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production
-
Kim MR, Manoukian R, Yeh R, Silbiger SM, Danilenko DM, Scully S, et al. Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production. Blood 2002;100:2330-40.
-
(2002)
Blood
, vol.100
, pp. 2330-2340
-
-
Kim, M.R.1
Manoukian, R.2
Yeh, R.3
Silbiger, S.M.4
Danilenko, D.M.5
Scully, S.6
-
23
-
-
0035575743
-
Forced expression of murine IL-17E induces growth retardation, jaundice, a Th2-biased response, and multiorgan inflammation in mice
-
Pan G, French D, Mao W, Maruoka M, Risser P, Lee J, et al. Forced expression of murine IL-17E induces growth retardation, jaundice, a Th2-biased response, and multiorgan inflammation in mice. J Immunol 2001;167:6559-67.
-
(2001)
J Immunol
, vol.167
, pp. 6559-6567
-
-
Pan, G.1
French, D.2
Mao, W.3
Maruoka, M.4
Risser, P.5
Lee, J.6
-
24
-
-
0036644547
-
New IL-17 family members promote Th1 or Th2 responses in the lung: In vivo function of the novel cytokine IL-25
-
Hurst SD, Muchamuel T, Gorman DM, Gilbert JM, Clifford T, Kwan S, et al. New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. J Immunol 2002;169:443-53.
-
(2002)
J Immunol
, vol.169
, pp. 443-453
-
-
Hurst, S.D.1
Muchamuel, T.2
Gorman, D.M.3
Gilbert, J.M.4
Clifford, T.5
Kwan, S.6
-
25
-
-
0035181582
-
Type 1 T regulatory cells
-
Roncarolo MG, Bacchetta R, Bordignon C, Narula S, Levings MK. Type 1 T regulatory cells. Immunol Rev 2001;182: 68-79.
-
(2001)
Immunol Rev
, vol.182
, pp. 68-79
-
-
Roncarolo, M.G.1
Bacchetta, R.2
Bordignon, C.3
Narula, S.4
Levings, M.K.5
-
26
-
-
0026625347
-
Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness
-
Bentley AM, Menz G, Storz C, Robinson DS, Bradley B, Jeffery PK, et al. Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness. Am Rev Respir Dis 1992;146: 500-6.
-
(1992)
Am Rev Respir Dis
, vol.146
, pp. 500-506
-
-
Bentley, A.M.1
Menz, G.2
Storz, C.3
Robinson, D.S.4
Bradley, B.5
Jeffery, P.K.6
-
27
-
-
0026610142
-
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
-
Robinson DS, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley AM, et al. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engt J Med 1992;326:298-304.
-
(1992)
N Engt J Med
, vol.326
, pp. 298-304
-
-
Robinson, D.S.1
Hamid, Q.2
Ying, S.3
Tsicopoulos, A.4
Barkans, J.5
Bentley, A.M.6
-
28
-
-
10544256182
-
IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: Evidence against intrinsic asthma being a distinct immunopathologic entity
-
Humbert M, Durham SR, Ying S, Kimmitt P, Barkans J, Assoufi B, et al. IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against intrinsic asthma being a distinct immunopathologic entity. Am J Respir Crit Care Med 1996;154: 1497-504.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 1497-1504
-
-
Humbert, M.1
Durham, S.R.2
Ying, S.3
Kimmitt, P.4
Barkans, J.5
Assoufi, B.6
-
29
-
-
0025760379
-
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
-
Hamid Q, Azzawi M, Ying S, Moqbel R, Wardlaw AJ, Corrigan CJ, et al. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest 1991;87:1541-6.
-
(1991)
J Clin Invest
, vol.87
, pp. 1541-1546
-
-
Hamid, Q.1
Azzawi, M.2
Ying, S.3
Moqbel, R.4
Wardlaw, A.J.5
Corrigan, C.J.6
-
30
-
-
0026583649
-
Expression of the potent inflammatory cytokines, granulocyte-macrophage- colony-stimulating factor and interleukin6 and interleukin-8, in bronchial epithelial cells of patients with asthma
-
Marini M, Vittori E, Hollemborg J, Mattoli S. Expression of the potent inflammatory cytokines, granulocyte-macrophage-colony-stimulating factor and interleukin6 and interleukin-8, in bronchial epithelial cells of patients with asthma. J Allergy Clin Immunol 1992;89:1001-9.
-
(1992)
J Allergy Clin Immunol
, vol.89
, pp. 1001-1009
-
-
Marini, M.1
Vittori, E.2
Hollemborg, J.3
Mattoli, S.4
-
31
-
-
0029055593
-
Expression of granulocyte/macrophage-colony-stimulating factor, interleukin-8 and RANTES in the bronchial epithelium of mild asthmatics is down-regulated by inhaled beclomethasone dipropionate
-
Davies RJ, Wang JH, Trigg CJ, Devalia JL. Expression of granulocyte/macrophage-colony-stimulating factor, interleukin-8 and RANTES in the bronchial epithelium of mild asthmatics is down-regulated by inhaled beclomethasone dipropionate. Int Arch Allergy Immunot 1995;107:428-9.
-
(1995)
Int Arch Allergy Immunot
, vol.107
, pp. 428-429
-
-
Davies, R.J.1
Wang, J.H.2
Trigg, C.J.3
Devalia, J.L.4
-
32
-
-
4444262198
-
IL-9 and its receptor in allergic and non allergic lung disease: Increased expression in asthma
-
Shimbara A, Christodoulopoulos P, Soussi-Gounni A, Olivenstein R, Nakamura Y, Levitt RC, et al. IL-9 and its receptor in allergic and non allergic lung disease: increased expression in asthma. J Allergy Clin Immunol 2000;105:108-15.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 108-115
-
-
Shimbara, A.1
Christodoulopoulos, P.2
Soussi-Gounni, A.3
Olivenstein, R.4
Nakamura, Y.5
Levitt, R.C.6
-
33
-
-
0033930058
-
Interleukin-9 receptor expression in asthmatic airways in vivo
-
Bhathena PR, Comhair SA, Holroyd KJ, Erzurum SC. Interleukin-9 receptor expression in asthmatic airways in vivo. Lung 2000;178:149-60.
-
(2000)
Lung
, vol.178
, pp. 149-160
-
-
Bhathena, P.R.1
Comhair, S.A.2
Holroyd, K.J.3
Erzurum, S.C.4
-
34
-
-
0030077464
-
Increased interleukin-10 messenger RNA expression in atopic allergy and asthma
-
Robinson DS, Tsicopoulos A, Meng Q, Durham S, Kay AB, Hamid Q. Increased interleukin-10 messenger RNA expression in atopic allergy and asthma. Am J Respir Cell Mol Biol 1996;14:113-7.
-
(1996)
Am J Respir Cell Mol Biol
, vol.14
, pp. 113-117
-
-
Robinson, D.S.1
Tsicopoulos, A.2
Meng, Q.3
Durham, S.4
Kay, A.B.5
Hamid, Q.6
-
35
-
-
0033678521
-
Kinetics of IL-10 production after segmental antigen challenge of atopic asthmatic subjects
-
Colavita AM, Hastie AT, Musani AI, Pascual RM, Reinach AJ, Lustine HT, et al. Kinetics of IL-10 production after segmental antigen challenge of atopic asthmatic subjects. J Allergy Clin Immunol 2000;106:880-6.
-
(2000)
J Allergy Clin Immunol
, vol.106
, pp. 880-886
-
-
Colavita, A.M.1
Hastie, A.T.2
Musani, A.I.3
Pascual, R.M.4
Reinach, A.J.5
Lustine, H.T.6
-
36
-
-
0033963493
-
IL-11 expression is increased in severe asthma: Association with epithelial cells and eosinophils
-
Minshall E, Chakir J, Laviolette M, Molet S, Zhu Z, Olivenstein R, et al. IL-11 expression is increased in severe asthma: association with epithelial cells and eosinophils. J Allergy Clin Immunol 2000;105:232-8.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 232-238
-
-
Minshall, E.1
Chakir, J.2
Laviolette, M.3
Molet, S.4
Zhu, Z.5
Olivenstein, R.6
-
37
-
-
0030638533
-
Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: Relationship to the eosinophil-actlve cytokines interleukin (IL)-5, granulocyte macrophage-colony- stimulatlng factor, and IL-3
-
Humbert M, Ying S, Corrigan C, Menz G, Barkans J, Pflster R, et al. Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: relationship to the eosinophil-actlve cytokines interleukin (IL)-5, granulocyte macrophage-colony- stimulatlng factor, and IL-3, Am J Respir Cell Mol Biol 1997;16:1-8.
-
(1997)
Am J Respir Cell Mol Biol
, vol.16
, pp. 1-8
-
-
Humbert, M.1
Ying, S.2
Corrigan, C.3
Menz, G.4
Barkans, J.5
Pflster, R.6
-
38
-
-
0033856743
-
Increased interleukin-13 mRNA expression in bronchoalveolar lavage cells of atopic patients with mild asthma after repeated low-dose allergen provocations
-
Prieto J, Lensmar C, Roquet A, van der Ploeg I, Gigliotti D, Eklund A, et al. Increased interleukin-13 mRNA expression in bronchoalveolar lavage cells of atopic patients with mild asthma after repeated low-dose allergen provocations. Respir Med 2000;94:806-14.
-
(2000)
Respir Med
, vol.94
, pp. 806-814
-
-
Prieto, J.1
Lensmar, C.2
Roquet, A.3
Van Der Ploeg, I.4
Gigliotti, D.5
Eklund, A.6
-
39
-
-
0031203153
-
Increased expression of interleukin-16 in bronchial mucosa of subjects with atopic asthma
-
Laberge S, Ernst P, Ghaffar O, Cruikshank WW, Kornfeld H, Center DM, et al. Increased expression of interleukin-16 in bronchial mucosa of subjects with atopic asthma. Am J Respir Cell Mol Biol 1997;17:193-202.
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, pp. 193-202
-
-
Laberge, S.1
Ernst, P.2
Ghaffar, O.3
Cruikshank, W.W.4
Kornfeld, H.5
Center, D.M.6
-
40
-
-
0033043167
-
Phenotype of IL-16-producing cells in bronchial mucosa: Evidence for the human eosinophil and mast cell as cellular sources of IL-16 in asthma
-
Laberge S, Pinsonneault S, Ernst P, Olivenstein R, Ghaffar O, Center DM, et al. Phenotype of IL-16-producing cells in bronchial mucosa: evidence for the human eosinophil and mast cell as cellular sources of IL-16 in asthma. Int Arch Allergy Immunol 1999;119:120-5.
-
(1999)
Int Arch Allergy Immunol
, vol.119
, pp. 120-125
-
-
Laberge, S.1
Pinsonneault, S.2
Ernst, P.3
Olivenstein, R.4
Ghaffar, O.5
Center, D.M.6
-
41
-
-
0030934422
-
Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy
-
Naseer T, Minshall EM, Leung DY, Laberge S, Ernst P, Martin RJ, et al. Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy. Am J Respir Crit Care Med 1997;155:845-51.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 845-851
-
-
Naseer, T.1
Minshall, E.M.2
Leung, D.Y.3
Laberge, S.4
Ernst, P.5
Martin, R.J.6
-
42
-
-
0033844525
-
Evidence for expression of eosinophil-associated IL-12 messenger RNA and immunoreactivity in bronchial asthma
-
Nutku E, Gounni AS, Olivenstein R, Hamid Q. Evidence for expression of eosinophil-associated IL-12 messenger RNA and immunoreactivity in bronchial asthma. J Allergy Clin Immunol 2000;106:288-92.
-
(2000)
J Allergy Clin Immunol
, vol.106
, pp. 288-292
-
-
Nutku, E.1
Gounni, A.S.2
Olivenstein, R.3
Hamid, Q.4
-
43
-
-
0032860656
-
Airway epithelium expresses interleukin-18
-
Cameron LA, Taha RA, Tsicopoulos A, Kurimoto M, Olivenstein R, Wallaert B, et al. Airway epithelium expresses interleukin-18. Eur Respir J 1999;14:553-9.
-
(1999)
Eur Respir J
, vol.14
, pp. 553-559
-
-
Cameron, L.A.1
Taha, R.A.2
Tsicopoulos, A.3
Kurimoto, M.4
Olivenstein, R.5
Wallaert, B.6
-
44
-
-
0030068235
-
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
-
Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener-Kronish JP, et al. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996;183:109-17.
-
(1996)
J Exp Med
, vol.183
, pp. 109-117
-
-
Corry, D.B.1
Folkesson, H.G.2
Warnock, M.L.3
Erle, D.J.4
Matthay, M.A.5
Wiener-Kronish, J.P.6
-
45
-
-
0029335074
-
Lnterleukin-4 is required for the induction of lung Th2 mucosal immunity
-
Coyle AJ, Le Gros G, Bertrand C, Tsuyuki S, Heusser CH, Kopf M, et al. lnterleukin-4 is required for the induction of lung Th2 mucosal immunity. Am J Respir Cell Mol Biol 1995;13:54-9.
-
(1995)
Am J Respir Cell Mol Biol
, vol.13
, pp. 54-59
-
-
Coyle, A.J.1
Le Gros, G.2
Bertrand, C.3
Tsuyuki, S.4
Heusser, C.H.5
Kopf, M.6
-
46
-
-
0031004365
-
Lnterleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice
-
Gavett SH, O'Hearn DJ, Karp CL, Patel EA, Schofield BH, Finkelman FD, et al. lnterleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice. Am J Physiol 1997;272:L253-L261.
-
(1997)
Am J Physiol
, vol.272
-
-
Gavett, S.H.1
O'Hearn, D.J.2
Karp, C.L.3
Patel, E.A.4
Schofield, B.H.5
Finkelman, F.D.6
-
47
-
-
0031044958
-
Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response
-
Zhang Y, Lamm WJ, Albert RK, Chi EY, Henderson Jr. WR, Lewis DB. Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response. Am J Respir Crit Care Med 1997;155:661-9.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 661-669
-
-
Zhang, Y.1
Lamm, W.J.2
Albert, R.K.3
Chi, E.Y.4
Henderson Jr., W.R.5
Lewis, D.B.6
-
48
-
-
0642283702
-
Regulation of eosinophil migration and Th2 cell function by IL-5 and eotaxin
-
Mattes J, Foster PS. Regulation of eosinophil migration and Th2 cell function by IL-5 and eotaxin. Curr Drug Targets Inflamm Allergy 2003;2:169-74.
-
(2003)
Curr Drug Targets Inflamm Allergy
, vol.2
, pp. 169-174
-
-
Mattes, J.1
Foster, P.S.2
-
49
-
-
0028817164
-
The effects of nebulized recombinant interferon-gamma in asthmatic airways
-
Boguniewicz M, Martin RJ, Martin D, Gibson U, Celniker A, Williams M, et al. The effects of nebulized recombinant interferon-gamma in asthmatic airways. J Allergy Clin Immunol 1995;95:133-5.
-
(1995)
J Allergy Clin Immunol
, vol.95
, pp. 133-135
-
-
Boguniewicz, M.1
Martin, R.J.2
Martin, D.3
Gibson, U.4
Celniker, A.5
Williams, M.6
-
50
-
-
6644223789
-
Effects of recombinant human interleukin 12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Bryan SA, O'Connor BJ, Matti S, Leckie MJ, Kanabar V, Khan J, et al. Effects of recombinant human interleukin 12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 2000;356:2149-53.
-
(2000)
Lancet
, vol.356
, pp. 2149-2153
-
-
Bryan, S.A.1
O'Connor, B.J.2
Matti, S.3
Leckie, M.J.4
Kanabar, V.5
Khan, J.6
-
51
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response
-
Leckie MJ, ten Brinke A, Khan J, Diamant Z, O'Connor BJ, Walls CM, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response. Lancet 2000;356:2144-8.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
Ten Brinke, A.2
Khan, J.3
Diamant, Z.4
O'Connor, B.J.5
Walls, C.M.6
-
52
-
-
0038643527
-
Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: A pilot study
-
Kips JC, O'Connor BJ, Langley SJ, Woodcock A, Kerstjens HA, Postma DS, et al Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. Am J Respir Crit Care Med 2003;167:1655-9.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1655-1659
-
-
Kips, J.C.1
O'Connor, B.J.2
Langley, S.J.3
Woodcock, A.4
Kerstjens, H.A.5
Postma, D.S.6
-
53
-
-
0037438409
-
Eosinophil's role remains uncertain as anti-interleukin5 only partially depletes numbers in asthmatic airway
-
Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS. Eosinophil's role remains uncertain as anti-interleukin5 only partially depletes numbers in asthmatic airway. Am J Respir Crit Care Med 2003;167:199-204.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 199-204
-
-
Flood-Page, P.T.1
Menzies-Gow, A.N.2
Kay, A.B.3
Robinson, D.S.4
-
54
-
-
4944235680
-
Anti-interleukin-5 therapy for asthma and hypereosinophilic syndrome
-
Kay AB, Klion AD. Anti-interleukin-5 therapy for asthma and hypereosinophilic syndrome. Immunol Allergy Clin North Am 2004;24:645-66.
-
(2004)
Immunol Allergy Clin North Am
, vol.24
, pp. 645-666
-
-
Kay, A.B.1
Klion, A.D.2
-
55
-
-
16044371529
-
Phenotypic and physiologic characterization of transgenic mice expressing interleukin-4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
-
Rankin JA, Picarella DE, Geba GP, Temann U, Prasad B, DiCosmo B, et al. Phenotypic and physiologic characterization of transgenic mice expressing interleukin-4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci USA 1996;93: 7821-5.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7821-7825
-
-
Rankin, J.A.1
Picarella, D.E.2
Geba, G.P.3
Temann, U.4
Prasad, B.5
DiCosmo, B.6
-
56
-
-
0030476382
-
Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction
-
Tang W, Geba GP, Zheng T, Ray P, Homer RJ, Kuhn C, et al. Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction. J Clin Invest 1996;98:2845-53.
-
(1996)
J Clin Invest
, vol.98
, pp. 2845-2853
-
-
Tang, W.1
Geba, G.P.2
Zheng, T.3
Ray, P.4
Homer, R.J.5
Kuhn, C.6
-
57
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersécrétion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersécré tion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-88.
-
(1999)
J Clin Invest
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
-
58
-
-
17444454662
-
Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma
-
Lee JJ, McGarry MP, Farmer SC, Denzler KL, Larson KA, Carrigan PE, et al. Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma. J Exp Med 1997;185:2143-56.
-
(1997)
J Exp Med
, vol.185
, pp. 2143-2156
-
-
Lee, J.J.1
McGarry, M.P.2
Farmer, S.C.3
Denzler, K.L.4
Larson, K.A.5
Carrigan, P.E.6
-
59
-
-
0032487434
-
Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness
-
Temann UA, Geba GP, Rankin JA, Flavell RA. Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J Exp Med 1998;188:1307-20.
-
(1998)
J Exp Med
, vol.188
, pp. 1307-1320
-
-
Temann, U.A.1
Geba, G.P.2
Rankin, J.A.3
Flavell, R.A.4
-
60
-
-
18344401643
-
Lnterleukin-9 promotes allergeninduced eosinophilic inflammation and airway hyperresponsiveness in transgenic mice
-
McLane MP, Haczku A, van de Rijn M, Weiss C, Ferrante V, MacDonald D, et al. lnterleukin-9 promotes allergeninduced eosinophilic inflammation and airway hyperresponsiveness in transgenic mice. Am J Respir Cell Mol Biol 1998;19:713-20.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 713-720
-
-
McLane, M.P.1
Haczku, A.2
Van De Rijn, M.3
Weiss, C.4
Ferrante, V.5
MacDonald, D.6
-
61
-
-
0033219725
-
Lnterleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice
-
Stampfli MR, Cwiartka M, Gajewska BU, Alvarez D, Ritz SA, Inman MD, et al. lnterleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice. Am J Respir Cell Mol Biol 1999;21:586-96.
-
(1999)
Am J Respir Cell Mol Biol
, vol.21
, pp. 586-596
-
-
Stampfli, M.R.1
Cwiartka, M.2
Gajewska, B.U.3
Alvarez, D.4
Ritz, S.A.5
Inman, M.D.6
-
62
-
-
85047693288
-
Inhibition of airway remodeling in IL-5-deficient mice
-
Cho JY, Miller M, Baek KJ, Han JW, Nayar J, Lee SY, et al. Inhibition of airway remodeling in IL-5-deficient mice. J Clin Invest 2004;113:551-60.
-
(2004)
J Clin Invest
, vol.113
, pp. 551-560
-
-
Cho, J.Y.1
Miller, M.2
Baek, K.J.3
Han, J.W.4
Nayar, J.5
Lee, S.Y.6
-
63
-
-
0028260378
-
Attenuation of allergic airway inflammation in IL-4 deficient mice
-
Brusselle GG, Kips JC, Tavernier JH, van der Heyden JG, Cuvelier CA, Pauwels RA, et al. Attenuation of allergic airway inflammation in IL-4 deficient mice. Clin Exp Allergy 1994;24:73-80.
-
(1994)
Clin Exp Allergy
, vol.24
, pp. 73-80
-
-
Brusselle, G.G.1
Kips, J.C.2
Tavernier, J.H.3
Van Der Heyden, J.G.4
Cuvelier, C.A.5
Pauwels, R.A.6
-
64
-
-
0033834828
-
Interleukin (IL)-5 but not immunoglobulin e reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice
-
Hamelmann E, Takeda K, Haczku A, Cieslewicz G, Shultz L, Hamid Q, et al. Interleukin (IL)-5 but not immunoglobulin E reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice. Am J Respir Cell Mol Biol/2000;23:327-34.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 327-334
-
-
Hamelmann, E.1
Takeda, K.2
Haczku, A.3
Cieslewicz, G.4
Shultz, L.5
Hamid, Q.6
-
65
-
-
0032557246
-
Requirement for gammadelta T cells in allergic airway inflammation
-
Zuany-Amorim C, Ruffie C, Haile S, Vargaftig BB, Pereira P, Pretolani M. Requirement for gammadelta T cells in allergic airway inflammation. Science 1998;280:1265-7.
-
(1998)
Science
, vol.280
, pp. 1265-1267
-
-
Zuany-Amorim, C.1
Ruffie, C.2
Haile, S.3
Vargaftig, B.B.4
Pereira, P.5
Pretolani, M.6
-
66
-
-
0029282377
-
Mast cells modulate allergic pulmonary eosinophilia in mice
-
Kung TT, Stelts D, Zurcher JA, Jones H, Umland SP, Kreutner W, et al. Mast cells modulate allergic pulmonary eosinophilia in mice. Am J Respir Cell Mol Biol 1995;12:404-9.
-
(1995)
Am J Respir Cell Mol Biol
, vol.12
, pp. 404-409
-
-
Kung, T.T.1
Stelts, D.2
Zurcher, J.A.3
Jones, H.4
Umland, S.P.5
Kreutner, W.6
-
67
-
-
0029959243
-
Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses
-
Brown DR, Fowell DJ, Corry DB, Wynn TA, Moskowitz NH, Cheever AW, et al. Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses. J Exp Med 1996;184:1295-304.
-
(1996)
J Exp Med
, vol.184
, pp. 1295-1304
-
-
Brown, D.R.1
Fowell, D.J.2
Corry, D.B.3
Wynn, T.A.4
Moskowitz, N.H.5
Cheever, A.W.6
-
68
-
-
0030953977
-
Aeroallergen-induced eosinophilfc Inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins
-
Hogan SP, Mould A, Kikutani H, Ramsay AJ, Foster PS. Aeroallergen-induced eosinophilfc Inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J Clin Invest 1997;99:1329-39.
-
(1997)
J Clin Invest
, vol.99
, pp. 1329-1339
-
-
Hogan, S.P.1
Mould, A.2
Kikutani, H.3
Ramsay, A.J.4
Foster, P.S.5
-
69
-
-
0032482159
-
Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice
-
Akimoto T, Numata F, Tamura M, Takata Y, Higashida N, Takashi T, et al. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice. JExpMed 1998;187:1537-42.
-
(1998)
JExpMed
, vol.187
, pp. 1537-1542
-
-
Akimoto, T.1
Numata, F.2
Tamura, M.3
Takata, Y.4
Higashida, N.5
Takashi, T.6
-
70
-
-
0032926518
-
STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells
-
Miyata S, Matsuyama T, Kodama T, Nishioka Y, Kuribayashi K, Takeda K, et al. STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells. Clin Exp Allergy 1999;29:114-23.
-
(1999)
Clin Exp Allergy
, vol.29
, pp. 114-123
-
-
Miyata, S.1
Matsuyama, T.2
Kodama, T.3
Nishioka, Y.4
Kuribayashi, K.5
Takeda, K.6
-
71
-
-
0030028768
-
Lnterleukin-5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
-
Foster PS, Hogan SP, Ramsay AJ, Matthaei Kl, Young IG. lnterleukin-5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 1996;183:195-201.
-
(1996)
J Exp Med
, vol.183
, pp. 195-201
-
-
Foster, P.S.1
Hogan, S.P.2
Ramsay, A.J.3
Matthaei, Kl.4
Young, I.G.5
-
72
-
-
0034041358
-
Allergen-induced airway inflammation and bronchial responsiveness in interleukin-5 receptor alpha chaindeficient mice
-
Tanaka H, Kawada N, Yamada T, Kawada K, Takatsu K, Nagai H. Allergen-induced airway inflammation and bronchial responsiveness in interleukin-5 receptor alpha chaindeficient mice. Clin Exp Allergy 2000; 30:874-81.
-
(2000)
Clin Exp Allergy
, vol.30
, pp. 874-881
-
-
Tanaka, H.1
Kawada, N.2
Yamada, T.3
Kawada, K.4
Takatsu, K.5
Nagai, H.6
-
73
-
-
0029266795
-
Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice
-
Brusselle G, Kips J, Joos G, Bluethmann H, Pauwels R. Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice. Am J Respir Cell Mol Biol 1995;12:254-9.
-
(1995)
Am J Respir Cell Mol Biol
, vol.12
, pp. 254-259
-
-
Brusselle, G.1
Kips, J.2
Joos, G.3
Bluethmann, H.4
Pauwels, R.5
-
74
-
-
0029969336
-
Effect of antigen provocation of IL-5 transgenic mice on eosinophil mobilization and bronchial hyperresponsiveness
-
Lefort J, Bachelet CM, Leduc D, Vargaftig BB. Effect of antigen provocation of IL-5 transgenic mice on eosinophil mobilization and bronchial hyperresponsiveness. J Allergy Clin Immunol 1996;97:788-99.
-
(1996)
J Allergy Clin Immunol
, vol.97
, pp. 788-799
-
-
Lefort, J.1
Bachelet, C.M.2
Leduc, D.3
Vargaftig, B.B.4
-
75
-
-
0033038648
-
IL-9 induces chemokine expression in lung epithelial cells and baseline airway eosinophilia in transgenic mice
-
Dong Q, Louahed J, Vink A, Sullivan C, Messier C, Zhou Y, et al. IL-9 induces chemokine expression in lung epithelial cells and baseline airway eosinophilia in transgenic mice. Eur J Immunol 1999;29:2130-9.
-
(1999)
Eur J Immunol
, vol.29
, pp. 2130-2139
-
-
Dong, Q.1
Louahed, J.2
Vink, A.3
Sullivan, C.4
Messier, C.5
Zhou, Y.6
-
76
-
-
0034517511
-
IL-9 expression by human eosinophils: Regulation by IL-1 beta and TNF-alpha
-
Gounni AS, Nutku E, Koussih L, Arts F, Louahed J, Levitt RC, et al. IL-9 expression by human eosinophils: regulation by IL-1 beta and TNF-alpha. J Allergy Clin Immunol 2000;106: 460-6.
-
(2000)
J Allergy Clin Immunol
, vol.106
, pp. 460-466
-
-
Gounni, A.S.1
Nutku, E.2
Koussih, L.3
Arts, F.4
Louahed, J.5
Levitt, R.C.6
-
77
-
-
0028173026
-
Airway epithelial cell expression of interleukin-6 in transgenic mice: Uncoupling of airway inflammation and bronchial hyperreactivity
-
DiCosmo B, Geba G, Picarella D, Elias J, Rankin J, Stripp B, et al. Airway epithelial cell expression of interleukin-6 in transgenic mice: uncoupling of airway inflammation and bronchial hyperreactivity. J Clin Invest 1994;94:2028-35.
-
(1994)
J Clin Invest
, vol.94
, pp. 2028-2035
-
-
DiCosmo, B.1
Geba, G.2
Picarella, D.3
Elias, J.4
Rankin, J.5
Stripp, B.6
-
78
-
-
0030025775
-
Lnterleukin-11: Stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness
-
Einarsson O, Geba GP, Zhu Z, Landry M, Elias JA. lnterleukin-11: Stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness. J Clin Invest 1996;97:915-24.
-
(1996)
J Clin Invest
, vol.97
, pp. 915-924
-
-
Einarsson, O.1
Geba, G.P.2
Zhu, Z.3
Landry, M.4
Elias, J.A.5
-
79
-
-
0034663769
-
IL-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production
-
Wang J, Homer RJ, Hong L, Cohn L, Lee CG, Jung S, et al. IL-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production. J Immunol 2000; 165:2222-31.
-
(2000)
J Immunol
, vol.165
, pp. 2222-2231
-
-
Wang, J.1
Homer, R.J.2
Hong, L.3
Cohn, L.4
Lee, C.G.5
Jung, S.6
-
80
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
Grunig G, Warnock M, Wakil AE, Venkayya R, Brombacher F, Rennick DM, et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998; 282:2261-3.
-
(1998)
Science
, vol.282
, pp. 2261-2263
-
-
Grunig, G.1
Warnock, M.2
Wakil, A.E.3
Venkayya, R.4
Brombacher, F.5
Rennick, D.M.6
-
81
-
-
0032536837
-
Signal transducer and activator of transcription factor 6 (Stato)deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
-
Kuperman D, Schofield B, Wills-Karp M, Grusby MJ. Signal transducer and activator of transcription factor 6 (Stato)deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J Exp Med 1998;187:939-48.
-
(1998)
J Exp Med
, vol.187
, pp. 939-948
-
-
Kuperman, D.1
Schofield, B.2
Wills-Karp, M.3
Grusby, M.J.4
-
82
-
-
0033696860
-
IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development
-
Townsend JM, Fallon GP, Matthews JD, Smith P, Jolin EH, McKenzie NA. IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development. Immunity 2000; 13:573-83.
-
(2000)
Immunity
, vol.13
, pp. 573-583
-
-
Townsend, J.M.1
Fallon, G.P.2
Matthews, J.D.3
Smith, P.4
Jolin, E.H.5
McKenzie, N.A.6
-
83
-
-
0034235875
-
Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity
-
Webb D, McKenzie A, Koskinen A, Yang M, Mattes J, Foster P. Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity. J Immunol 2000; 165:108-13.
-
(2000)
J Immunol
, vol.165
, pp. 108-113
-
-
Webb, D.1
McKenzie, A.2
Koskinen, A.3
Yang, M.4
Mattes, J.5
Foster, P.6
-
84
-
-
0034045707
-
Lnterleukin-9 upregulates mucus expression in the airways
-
Louahed J, Toda M, Jen J, Hamid Q, Renauld JC, Levitt RC, et al. lnterleukin-9 upregulates mucus expression in the airways. Am J Respir Cell Mol Biol 2000;22:649-56.
-
(2000)
Am J Respir Cell Mol Biol
, vol.22
, pp. 649-656
-
-
Louahed, J.1
Toda, M.2
Jen, J.3
Hamid, Q.4
Renauld, J.C.5
Levitt, R.C.6
-
85
-
-
0032901154
-
Regulation of 15-lipoxygenase expression and mucus secretion by IL-4 in human bronchial epithelial cells
-
Jayawickreme SP, Gray T, Nettesheim P, Eling T. Regulation of 15-lipoxygenase expression and mucus secretion by IL-4 in human bronchial epithelial cells. Am J Physiol 1999;276:L596-L603.
-
(1999)
Am J Physiol
, vol.276
-
-
Jayawickreme, S.P.1
Gray, T.2
Nettesheim, P.3
Eling, T.4
-
86
-
-
0033563258
-
IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo
-
Dabbagh K, Takeyama K, Lee HM, Ueki IF, Lausier JA, Nadel JA. IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo. J Immunot 1999;162: 6233-7.
-
(1999)
J Immunot
, vol.162
, pp. 6233-6237
-
-
Dabbagh, K.1
Takeyama, K.2
Lee, H.M.3
Ueki, I.F.4
Lausier, J.A.5
Nadel, J.A.6
-
87
-
-
0033562979
-
Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils
-
Cohn L, Homer RJ, MacLeod H, Mohrs M, Brombacher F, Bottomly K. Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils. J Immunol 1999;162:6178-83.
-
(1999)
J Immunol
, vol.162
, pp. 6178-6183
-
-
Cohn, L.1
Homer, R.J.2
MacLeod, H.3
Mohrs, M.4
Brombacher, F.5
Bottomly, K.6
-
88
-
-
0032700856
-
Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells
-
Longphre M, Li D, Gallup M, Drori E, Ordonez CL, Redman T, et al. Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells. J Clin Invest 1999;104:1375-82.
-
(1999)
J Clin Invest
, vol.104
, pp. 1375-1382
-
-
Longphre, M.1
Li, D.2
Gallup, M.3
Drori, E.4
Ordonez, C.L.5
Redman, T.6
-
89
-
-
0034091092
-
Morphometry explains variation in airway responsiveness in transgenic mice overexpressing interleukin-6 and interleukin-11 in the lung
-
Kuhn C, Homer R, Zhu Z, Ward N, Elias J. Morphometry explains variation in airway responsiveness in transgenic mice overexpressing interleukin-6 and interleukin-11 in the lung. Chest2000;117(suppl5):260S-262S.
-
(2000)
Chest
, vol.117
, Issue.5 SUPPL.
-
-
Kuhn, C.1
Homer, R.2
Zhu, Z.3
Ward, N.4
Elias, J.5
-
90
-
-
0031943618
-
The interleukin-12/interleukin-12receptor system: Role in normal and pathologic immune responses
-
Gately MK, Renzetti LM, Magram J, Stern AS, Adorini L, Gubler U, et al. The interleukin-12/interleukin-12receptor system: role in normal and pathologic immune responses. Annu Rev Immunol 1998;16:495-521.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 495-521
-
-
Gately, M.K.1
Renzetti, L.M.2
Magram, J.3
Stern, A.S.4
Adorini, L.5
Gubler, U.6
-
91
-
-
0028821825
-
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice
-
Gavett SH, O'Hearn DJ, Li X, Huang SK, Finkelman FD, Wills-Karp M. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med 1995;182:1527-36.
-
(1995)
J Exp Med
, vol.182
, pp. 1527-1536
-
-
Gavett, S.H.1
O'Hearn, D.J.2
Li, X.3
Huang, S.K.4
Finkelman, F.D.5
Wills-Karp, M.6
-
92
-
-
0029847440
-
Interleukin-12 prevents antigen-induced eosinophil recruitment into mouse airways
-
Iwamoto I, Kumano K, Kasai M, Kurasawa K, Nakao A. Interleukin-12 prevents antigen-induced eosinophil recruitment into mouse airways. Am J Respir Crit Care Med 1996;154:1257-60.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 1257-1260
-
-
Iwamoto, I.1
Kumano, K.2
Kasai, M.3
Kurasawa, K.4
Nakao, A.5
-
93
-
-
0030042544
-
Interleukin-12 inhibits antigen-induced airway hyperresponsiveness in mice
-
Kips JC, Brusselle GJ, Joos GF, Peleman RA, Tavernier JH, Devos RR, et al. Interleukin-12 inhibits antigen-induced airway hyperresponsiveness in mice. Am J Respir Crit Care Med 1996;153:535-9.
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 535-539
-
-
Kips, J.C.1
Brusselle, G.J.2
Joos, G.F.3
Peleman, R.A.4
Tavernier, J.H.5
Devos, R.R.6
-
94
-
-
0031952393
-
Mucosal IL-12 gene delivery inhibits allergic airways disease and restores local antiviral immunity
-
Hogan SP, Foster PS, Tan X, Ramsay AJ. Mucosal IL-12 gene delivery inhibits allergic airways disease and restores local antiviral immunity. Eur J Immunol 1998;28:413-23.
-
(1998)
Eur J Immunol
, vol.28
, pp. 413-423
-
-
Hogan, S.P.1
Foster, P.S.2
Tan, X.3
Ramsay, A.J.4
-
95
-
-
0033194627
-
Regulation of allergic mucosal sensitization by interleukin-12 gene transfer to the airway
-
Stampfli MR, Scott Neigh G, Wiley RE, Cwiartka M, Ritz SA, Hitt MM, et al. Regulation of allergic mucosal sensitization by interleukin-12 gene transfer to the airway. Am J Respir Cell Mol Biol 1999;21:317-26.
-
(1999)
Am J Respir Cell Mol Biol
, vol.21
, pp. 317-326
-
-
Stampfli, M.R.1
Scott Neigh, G.2
Wiley, R.E.3
Cwiartka, M.4
Ritz, S.A.5
Hitt, M.M.6
-
96
-
-
0033979544
-
Vaccination with heat-killed Listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: Role of CD8+ T cells and IL-18
-
Hansen G, Yeung VP, Berry G, Umetsu DT, DeKruyff RH. Vaccination with heat-killed Listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: role of CD8+ T cells and IL-18. J Immunol 2000;164:223-30.
-
(2000)
J Immunol
, vol.164
, pp. 223-230
-
-
Hansen, G.1
Yeung, V.P.2
Berry, G.3
Umetsu, D.T.4
DeKruyff, R.H.5
-
97
-
-
0033049930
-
Administration of interleukin-12 prevents mite der p 1 allergen-lgE antibody production and airway eosinophil infiltration in an animal model of airway inflammation
-
Lee YL, Fu CL, Ye YL, Chiang BL. Administration of interleukin-12 prevents mite Der p 1 allergen-lgE antibody production and airway eosinophil infiltration in an animal model of airway inflammation. Scand J Immunol 1999;49: 229-36.
-
(1999)
Scand J Immunol
, vol.49
, pp. 229-236
-
-
Lee, Y.L.1
Fu, C.L.2
Ye, Y.L.3
Chiang, B.L.4
-
98
-
-
0033862133
-
IL-12 regulates bone marrow eosinophilia and airway eotaxin levels induced by airway allergen exposure
-
Zhao LL, Linden A, Sjostrand M, Cui ZH, Lotvall J, Jordana M. IL-12 regulates bone marrow eosinophilia and airway eotaxin levels induced by airway allergen exposure. Allergy 2000;55:749-56.
-
(2000)
Allergy
, vol.55
, pp. 749-756
-
-
Zhao, L.L.1
Linden, A.2
Sjostrand, M.3
Cui, Z.H.4
Lotvall, J.5
Jordana, M.6
-
99
-
-
0035865404
-
IL-12dependent vascular cell adhesion molecule-1 expression contributes to airway eosinophilic inflammation in a mouse model of asthma-like reaction
-
Wang S, Fan Y, Han X, Yang J, Bilenki L, Yang X. IL-12dependent vascular cell adhesion molecule-1 expression contributes to airway eosinophilic inflammation in a mouse model of asthma-like reaction. J Immunol 2001;166: 2741-9.
-
(2001)
J Immunol
, vol.166
, pp. 2741-2749
-
-
Wang, S.1
Fan, Y.2
Han, X.3
Yang, J.4
Bilenki, L.5
Yang, X.6
-
100
-
-
0031308181
-
Role of IFN-gamma in the inhibition of the allergic airway inflammation caused by IL-12
-
Bruselle GG, Kips JC, Peleman RA, Joos GF, Devos RR, Tavernier JH, et al. Role of IFN-gamma in the inhibition of the allergic airway inflammation caused by IL-12. Am J Respir Cell Mol Biol 1997;17:767-71.
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, pp. 767-771
-
-
Bruselle, G.G.1
Kips, J.C.2
Peleman, R.A.3
Joos, G.F.4
Devos, R.R.5
Tavernier, J.H.6
-
101
-
-
0031705349
-
Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development
-
Stoll S, Jonuleit H, Schmitt E, Muller G, Yamauchi H, Kurimoto M, et al. Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development. Eur J Immunol 1998;28:3231-9.
-
(1998)
Eur J Immunol
, vol.28
, pp. 3231-3239
-
-
Stoll, S.1
Jonuleit, H.2
Schmitt, E.3
Muller, G.4
Yamauchi, H.5
Kurimoto, M.6
-
102
-
-
0034162514
-
IFN-gamma-inducing factor (IL-18) increases allergic sensitization, serum IgE, Th2 cytokines, and airway eosinophilia in a mouse model of allergic asthma
-
Wild JS, Sigounas A, Sur N, Siddiqui MS, Alam R, Kurimoto M, et al. IFN-gamma-inducing factor (IL-18) increases allergic sensitization, serum IgE, Th2 cytokines, and airway eosinophilia in a mouse model of allergic asthma. J Immunol 2000;164:2701-10.
-
(2000)
J Immunol
, vol.164
, pp. 2701-2710
-
-
Wild, J.S.1
Sigounas, A.2
Sur, N.3
Siddiqui, M.S.4
Alam, R.5
Kurimoto, M.6
-
103
-
-
0032844961
-
Lnterleukin-18 enhances antigeninduced eosinophil recruitment into the mouse airways
-
Kumano K, Nakao A, Nakajima H, Hayashi F, Kurimoto M, Okamura H, et al. lnterleukin-18 enhances antigeninduced eosinophil recruitment into the mouse airways. Am J Respir Crit Care Med 1999;160:873-8.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 873-878
-
-
Kumano, K.1
Nakao, A.2
Nakajima, H.3
Hayashi, F.4
Kurimoto, M.5
Okamura, H.6
-
104
-
-
0032209767
-
Differential effects of endogenous and exogenous interferon-gamma on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma
-
Hofstra CL, Van Ark I, Hofman G, Nijkamp FP, Jardieu PM, Van Oosterhout AJ. Differential effects of endogenous and exogenous interferon-gamma on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma. Am J Respir Cell Mol Biol 1998; 19:826-35.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 826-835
-
-
Hofstra, C.L.1
Van Ark, I.2
Hofman, G.3
Nijkamp, F.P.4
Jardieu, P.M.5
Van Oosterhout, A.J.6
-
105
-
-
0033985217
-
IL-18 deficiency selectively enhances allergen-induced eosinophilia in mice
-
Kodama T, Matsuyama T, Kuribayashi K, Nishioka Y, Sugita M, Akira S, et al. IL-18 deficiency selectively enhances allergen-induced eosinophilia in mice. J Allergy Clin Immunol 2000;105:45-53.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 45-53
-
-
Kodama, T.1
Matsuyama, T.2
Kuribayashi, K.3
Nishioka, Y.4
Sugita, M.5
Akira, S.6
-
106
-
-
0027409773
-
Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+ T cells
-
Iwamoto I, Nakajima H, Endo H, Yoshida S. Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+ T cells. J Exp Med 1993;177:573-6.
-
(1993)
J Exp Med
, vol.177
, pp. 573-576
-
-
Iwamoto, I.1
Nakajima, H.2
Endo, H.3
Yoshida, S.4
-
107
-
-
0030587861
-
Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice
-
Li XM, Chopra RK, Chou TY, Schofield BH, Wills-Karp M, Huang SK. Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice. J Immunol 1996;157: 3216-9.
-
(1996)
J Immunol
, vol.157
, pp. 3216-3219
-
-
Li, X.M.1
Chopra, R.K.2
Chou, T.Y.3
Schofield, B.H.4
Wills-Karp, M.5
Huang, S.K.6
-
108
-
-
0032719182
-
Role of JAK2 signal transductional pathway in activation and survival of human peripheral eosinophils by interferon-gamma (IFN-gamma)
-
Ochiai K, Tanabe E, Ishihara C, Kagami M, Sugiyama T, Sueishi M, et al. Role of JAK2 signal transductional pathway in activation and survival of human peripheral eosinophils by interferon-gamma (IFN-gamma). Clin Exp Immunol 1999;118:340-3.
-
(1999)
Clin Exp Immunol
, vol.118
, pp. 340-343
-
-
Ochiai, K.1
Tanabe, E.2
Ishihara, C.3
Kagami, M.4
Sugiyama, T.5
Sueishi, M.6
-
109
-
-
12944267034
-
IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization
-
Makela MJ, Kanehiro A, Borish L, Dakhama A, Loader J, Joetham A, et al. IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization. Proc Natl Acad Sci USA 2000;97:6007-12.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6007-6012
-
-
Makela, M.J.1
Kanehiro, A.2
Borish, L.3
Dakhama, A.4
Loader, J.5
Joetham, A.6
-
110
-
-
0034008781
-
IL-10 reduces Th2 cytokine production and eosinophilia but augments airway reactivity in allergic mice
-
van Scott MR, Justice JP, Bradfield JF, Enright E, Sigounas A, Sur S. IL-10 reduces Th2 cytokine production and eosinophilia but augments airway reactivity in allergic mice. Am J Physiol Lung Cell Mol Physiol 2000;278:L667-L674.
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.278
-
-
Van Scott, M.R.1
Justice, J.P.2
Bradfield, J.F.3
Enright, E.4
Sigounas, A.5
Sur, S.6
-
111
-
-
0034045109
-
Endogenous interleukin-10 suppresses allergen-induced airway inflammation and non specific airway responsiveness
-
Tournoy KG, Kips JC, Pauwels RA. Endogenous interleukin-10 suppresses allergen-induced airway inflammation and non specific airway responsiveness. Clin Exp Allergy 2000; 30:775-83.
-
(2000)
Clin Exp Allergy
, vol.30
, pp. 775-783
-
-
Tournoy, K.G.1
Kips, J.C.2
Pauwels, R.A.3
-
112
-
-
0035012780
-
IL-10 gene knockout attenuates allergen-induced airway hyperresponsiveness in C57BL/6 mice
-
Justice JP, Shibata Y, Sur S, Mustafa J, Fan M, Van Scott MR. IL-10 gene knockout attenuates allergen-induced airway hyperresponsiveness in C57BL/6 mice. Am J Physiol Lung Cell Mol Physiol 2001;280:L363-L368.
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.280
-
-
Justice, J.P.1
Shibata, Y.2
Sur, S.3
Mustafa, J.4
Fan, M.5
Van Scott, M.R.6
-
113
-
-
0029075489
-
Lnterleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice
-
Zuany-Amorim C, Haile S, Leduc D, Dumarey C, Huerre M, Vargaftig BB, et al. lnterleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice. J Clin Invest 1995;95:2644-51.
-
(1995)
J Clin Invest
, vol.95
, pp. 2644-2651
-
-
Zuany-Amorim, C.1
Haile, S.2
Leduc, D.3
Dumarey, C.4
Huerre, M.5
Vargaftig, B.B.6
-
114
-
-
0030013191
-
Modulation by IL-10 of antigeninduced IL-5 generation, and CD4+ T lymphocyte and eosinophil infiltration into the mouse peritoneal cavity
-
Zuany-Amorim C, Creminon C, Nevers MC, Nahori MA, Vargaftig BB, Pretolani M. Modulation by IL-10 of antigeninduced IL-5 generation, and CD4+ T lymphocyte and eosinophil infiltration into the mouse peritoneal cavity. J Immunol 1996;157:377-84.
-
(1996)
J Immunol
, vol.157
, pp. 377-384
-
-
Zuany-Amorim, C.1
Creminon, C.2
Nevers, M.C.3
Nahori, M.A.4
Vargaftig, B.B.5
Pretolani, M.6
-
115
-
-
6444222929
-
New drugs for asthma
-
Barnes PJ. New drugs for asthma. Not Rev Drug Discov 2004;3: 831-44.
-
(2004)
Not Rev Drug Discov
, vol.3
, pp. 831-844
-
-
Barnes, P.J.1
-
117
-
-
4143098139
-
The relationship between asthma and COPD. Lessons from transgenic mice
-
discussion: 159S-161S
-
Elias J. The relationship between asthma and COPD. Lessons from transgenic mice. Chest 2004;126:111S-116S discussion: 159S-161S.
-
(2004)
Chest
, vol.126
-
-
Elias, J.1
|