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Volumn 187, Issue 9, 1998, Pages 1537-1542

Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; OVALBUMIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 0032482159     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.9.1537     Document Type: Article
Times cited : (288)

References (37)
  • 1
    • 0024491638 scopus 로고
    • Association of asthma with serum IgE levels and skin test reactivity to allergens
    • Burrow, B., F. Martines, M. Halonen, R. Barbee, and M. Cline. 1989. Association of asthma with serum IgE levels and skin test reactivity to allergens. N. Engl. J. Med. 320:271-277.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 271-277
    • Burrow, B.1    Martines, F.2    Halonen, M.3    Barbee, R.4    Cline, M.5
  • 2
    • 0026051430 scopus 로고
    • Relationship between airway hyperresponsiveness and serum IgE in child with asthma and in apparently normal children
    • Sears, M.R., B. Burrows, E.M. Flannery, G.P. Herbinson, C.J. Hewitt, and M.D. Holdaway. 1991. Relationship between airway hyperresponsiveness and serum IgE in child with asthma and in apparently normal children. N. Engl. J. Med. 325:1067-1071.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 1067-1071
    • Sears, M.R.1    Burrows, B.2    Flannery, E.M.3    Herbinson, G.P.4    Hewitt, C.J.5    Holdaway, M.D.6
  • 5
    • 0025008579 scopus 로고
    • The eosinophil and bronchial asthma. Current understanding
    • Gleich, G. 1990. The eosinophil and bronchial asthma. Current understanding. J. Allergy Clin. Immunol. 85:422-436.
    • (1990) J. Allergy Clin. Immunol. , vol.85 , pp. 422-436
    • Gleich, G.1
  • 6
    • 0025900437 scopus 로고
    • Asthma and inflammation
    • Kay, A.B. 1991. Asthma and inflammation. J. Allergy Clin. Immunol. 87:893-910.
    • (1991) J. Allergy Clin. Immunol. , vol.87 , pp. 893-910
    • Kay, A.B.1
  • 7
    • 0023069479 scopus 로고
    • B cell stimulatory factor-1/ interleukin-4
    • Paul, W.E., and J. Ohara. 1987. B cell stimulatory factor-1/ interleukin-4. Annu. Rev. Immunol. 5:429-459.
    • (1987) Annu. Rev. Immunol. , vol.5 , pp. 429-459
    • Paul, W.E.1    Ohara, J.2
  • 8
    • 0025764757 scopus 로고
    • Interleukin-4: A prototypic immunoregulatory lymphokine
    • Paul, W.E. 1991. Interleukin-4: a prototypic immunoregulatory lymphokine. Blood. 77:1859-1870.
    • (1991) Blood , vol.77 , pp. 1859-1870
    • Paul, W.E.1
  • 9
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kühn, R., K. Rajewsky, and W. Müller. 1991. Generation and analysis of interleukin-4 deficient mice. Science. 254: 707-710.
    • (1991) Science , vol.254 , pp. 707-710
    • Kühn, R.1    Rajewsky, K.2    Müller, W.3
  • 14
    • 0028845212 scopus 로고
    • Cytokine receptor signaling
    • Ihle, J.N. 1995. Cytokine receptor signaling. Nature. 377: 591-594.
    • (1995) Nature , vol.377 , pp. 591-594
    • Ihle, J.N.1
  • 16
    • 0029057858 scopus 로고
    • Cloning of murine stat6 and human stat6, stat proteins that are tyrosine phosphorylated in response to IL-4 and IL-3 but are not required for mitogenesis
    • Quelle, F.W., K. Shimoda, W. Thierfelder, C. Fischer, A. Kim, S.M. Ruben, J.L. Cleveland, J.H. Pierce, A.H. Keegan, K. Nelms, et al. 1995. Cloning of murine stat6 and human stat6, stat proteins that are tyrosine phosphorylated in response to IL-4 and IL-3 but are not required for mitogenesis. Mol. Cell. Biol. 15:3336-3343.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3336-3343
    • Quelle, F.W.1    Shimoda, K.2    Thierfelder, W.3    Fischer, C.4    Kim, A.5    Ruben, S.M.6    Cleveland, J.L.7    Pierce, J.H.8    Keegan, A.H.9    Nelms, K.10
  • 19
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    • Kaplan, M.H., U. Schindler, S.T. Smiley, and M.J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity. 4:313-319.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 21
    • 0031029888 scopus 로고    scopus 로고
    • Interleukin-4 and its receptor: Essential mediators of the allergic response
    • Ryan, J.J. 1997. Interleukin-4 and its receptor: essential mediators of the allergic response. J. Allergy Clin. Immunol. 99:1-5.
    • (1997) J. Allergy Clin. Immunol. , vol.99 , pp. 1-5
    • Ryan, J.J.1
  • 22
    • 0028455633 scopus 로고
    • Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia
    • Gavett, S.H., X. Chen, F. Finkelman, and M. Wills-Karp. 1994. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Respir. Cell. Mol. Biol. 10:587-593.
    • (1994) Am. J. Respir. Cell. Mol. Biol. , vol.10 , pp. 587-593
    • Gavett, S.H.1    Chen, X.2    Finkelman, F.3    Wills-Karp, M.4
  • 24
    • 0027197709 scopus 로고
    • Allergen exposure induces the activation of allergen-specific Th2 cells in airway mucosa of patients with allergic respiratory disorders
    • Del Prete, G.F., M. De Carli, M.M. D'Elios, P. Maestrelli, M. Ricci, L. Fabbri, and S. Romagnani, 1993. Allergen exposure induces the activation of allergen-specific Th2 cells in airway mucosa of patients with allergic respiratory disorders. Eur. J. Immunol. 23:1445-1449.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1445-1449
    • Del Prete, G.F.1    De Carli, M.2    D'Elios, M.M.3    Maestrelli, P.4    Ricci, M.5    Fabbri, L.6    Romagnani, S.7
  • 25
    • 0030028768 scopus 로고    scopus 로고
    • Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
    • Foster, P.S., S.P. Hogan, A.J. Ramsay, K.I. Matthaei, and I.G. Young. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195-201.
    • (1996) J. Exp. Med. , vol.183 , pp. 195-201
    • Foster, P.S.1    Hogan, S.P.2    Ramsay, A.J.3    Matthaei, K.I.4    Young, I.G.5
  • 26
  • 27
    • 0030953977 scopus 로고    scopus 로고
    • Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins
    • Horgan, S.P., A. Mould, H. Kikutani, A.J. Ramsay, and P.S. Foster. 1997. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J. Clin. Invest. 99:1329-1339.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1329-1339
    • Horgan, S.P.1    Mould, A.2    Kikutani, H.3    Ramsay, A.J.4    Foster, P.S.5
  • 28
    • 0028341465 scopus 로고
    • Human interleukin-13 activates the interleukin-4-dependent transcription factor NF-IL-4 sharing a DNA binding motif with an interferon-γ-induced nuclear binding factor
    • Köhler, I., P. Alliger, A. Minty, D. Caput, P. Ferrara, B. Holl-Neugebauer, G. Rank, and E.P. Rieber. 1994. Human interleukin-13 activates the interleukin-4-dependent transcription factor NF-IL-4 sharing a DNA binding motif with an interferon-γ-induced nuclear binding factor. FEBS Lett. 345:187-192.
    • (1994) FEBS Lett. , vol.345 , pp. 187-192
    • Köhler, I.1    Alliger, P.2    Minty, A.3    Caput, D.4    Ferrara, P.5    Holl-Neugebauer, B.6    Rank, G.7    Rieber, E.P.8
  • 29
    • 0030587813 scopus 로고    scopus 로고
    • Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice
    • Takeda, K., M. Kamanaka, T. Tanaka, T. Kishimoto, and S. Akira. 1996. Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice. J. Immunol. 157:3220-3222.
    • (1996) J. Immunol. , vol.157 , pp. 3220-3222
    • Takeda, K.1    Kamanaka, M.2    Tanaka, T.3    Kishimoto, T.4    Akira, S.5
  • 30
    • 0030988307 scopus 로고    scopus 로고
    • Interleukin 4 and interleukin 13: Same response, different receptors
    • Callard, R.E., D.J. Matthews, and L.M. Hibbert. 1997. Interleukin 4 and interleukin 13: same response, different receptors. Biochem. Soc. Trans. 25:451-435.
    • (1997) Biochem. Soc. Trans. , vol.25 , pp. 451-1435
    • Callard, R.E.1    Matthews, D.J.2    Hibbert, L.M.3
  • 31
    • 0028797453 scopus 로고
    • Function of the interleukin-2 (IL-2) receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15
    • Matthew, D.J., P.A. Clark, J. Herbert, G. Morgan, R.J. Armitage, C. Kinnon, A. Minty, K.H. Grabstein, D. Caput, P. Ferrara, and R. Callard. 1995. Function of the interleukin-2 (IL-2) receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15. Blood. 85:38-42.
    • (1995) Blood , vol.85 , pp. 38-42
    • Matthew, D.J.1    Clark, P.A.2    Herbert, J.3    Morgan, G.4    Armitage, R.J.5    Kinnon, C.6    Minty, A.7    Grabstein, K.H.8    Caput, D.9    Ferrara, P.10    Callard, R.11
  • 32
    • 0030028353 scopus 로고    scopus 로고
    • Signal transduction pathway of interleukin-4 and interleukin-13 in human B cells derived from X-linked severe combined immunodeficiency patients
    • Izuhara, K., T. Heike, T. Otsuka, K. Yamaoka, M. Mayumi, T. Imamura, Y. Niho, and N. Harada. 1996. Signal transduction pathway of interleukin-4 and interleukin-13 in human B cells derived from X-linked severe combined immunodeficiency patients. J. Biol. Chem. 271:619-622.
    • (1996) J. Biol. Chem. , vol.271 , pp. 619-622
    • Izuhara, K.1    Heike, T.2    Otsuka, T.3    Yamaoka, K.4    Mayumi, M.5    Imamura, T.6    Niho, Y.7    Harada, N.8
  • 36
    • 0031278431 scopus 로고    scopus 로고
    • Induction of STAT protein signaling through the CD40 receptor in B lymphocytes: Distinct STAT activation following surface Ig and CD40 receptor engagement
    • Karras, J.G., Z. Wang, L. Hou, D.A. Frank, and T.L. Rothstein. 1997. Induction of STAT protein signaling through the CD40 receptor in B lymphocytes: distinct STAT activation following surface Ig and CD40 receptor engagement. J. Immunol. 159:4350-4355.
    • (1997) J. Immunol. , vol.159 , pp. 4350-4355
    • Karras, J.G.1    Wang, Z.2    Hou, L.3    Frank, D.A.4    Rothstein, T.L.5
  • 37
    • 0029796717 scopus 로고    scopus 로고
    • In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production
    • Brewer, J.M., M. Conacher, A. Satoskar, H. Bluethmann, and J. Alexander. 1996. In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production. Eur. J. Immunol. 26:2062-2066.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2062-2066
    • Brewer, J.M.1    Conacher, M.2    Satoskar, A.3    Bluethmann, H.4    Alexander, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.