IL-18 deficiency selectively enhances allergen-induced eosinophilia in mice

Journal of Allergy and Clinical Immunology

Volumn 105, Issue 1 I, 2000, Pages 45-53

  Kodama, Taku ^a   Matsuyama, Tomohiro ^a   Kuribayashi, Kozo ^a   Nishioka, Yasuhiro ^a   Sugita, Minoru ^a   Akira, Shizuo ^b   Nakanishi, Kenji ^a   Okamura, Haruki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Bronchial asthma; Eosinophil; Fas ligand; IL 18

Indexed keywords

ALLERGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 18; RECOMBINANT INTERLEUKIN 18;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EOSINOPHILIA; IMMUNE DEFICIENCY; IMMUNITY; IMMUNOMODULATION; INFLAMMATION; MALE; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0033985217     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(00)90176-3     Document Type: Article

References (43)

1. Bochner BS, Undem BJ, Lichtenstein LM. Immunological aspects of allergic asthma. Annu Rev Immunol 1994;12:295-335.
2. Kay AB. Asthma and inflammation. J Allergy Clin Immunol 1991;87:893-910.
3. Bousquet J, Chanez P, Lacoste JY, Bameon G, Ghavanian N, Enander I, et al. Eosinophilic inflammation in asthma. N Engl J Med 1990;323:1033-9.
4. Walker C, Kaegi MK, Braun P, Blaser K. Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity. J Allergy Clin Immunol 1991;88:935-42.
5. Robinson DR, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley AM, et al. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298-304.
6. Hamelmann E, Oshiba A, Loader J, Larsen GL, Gleich G, Lee J, et al. Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization. Am J Respir Crit Care Med 1997;155:819-25.
7. Akimoto T, Numata F, Tamura M, Takata Y, Higashida N, Takashi T, et al. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT) 6-deficient mice. J Exp Med 1998;187:1537-42.
8. + T cells. Clin Exp Allergy 1999;29:114-23.
9. Lack G, Bradley KL, Hamelmann E, Renz H, Loader J, Leung DYM, et al. Nebulized IFN-γ inhibits the development of secondary allergic responses in mice. J Immunol 1996;157:1432-9.
10. Li X-M, Chopra RK, Chou T-Y, Schofield BH, Wills-Karp M, Huang S-K. Mucosal IFN-γ gene transfer inhibits pulmonary allergic responses in mice. J Immunol 1996;157:3216-9.
11. Boguniewicz M, Martin RJ, Martin D, Gibson U, Celniker A, Williams M, et al. The effects of nebulized recombinant IFN-γ in asthmatic airways. J Allergy Clin Immunol 1995;95:133-5.
12. Ushio S, Namba M, Okura T, Hattori K, Nukada Y, Akita K, et al. Cloning of the cDNA for human IFN-γ-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol 1996;156:4274-9.
13. Okamura H, Tsutsui H, Komatsu T, Yutsudo M, Hakura A, Tanimoto T, et al. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 1995;378:88-91.
14. Takeda K, Tsutsui H, Yoshimoto T, Adachi O, Yoshida N, Kishimoto T, et al. Defective NK cell activity and ThI response in IL-18-deficient mice. Immunity 1998;8:383-90.
15. Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 1996;183:195-201.
16. Kodama T, Matsuyama T, Miyata S, Nishimura H, Nishioka Y, Kitada O, et al. Kinetics of apoptosis in the lung of mice with allergic airway inflammation. Clin Exp Allergy 1998;28:1435-43.
17. Hyodo Y, Matsui K, Hayashi N, Tsutsui H, Kasniwamura S, Yamauchi H, et al. IL-18 up-regulates perforin-mediated NK activity without increasing perform messenger RNA expression by binding to constitutively expressed IL-18R. J Immunol 1999;162:1662-8.
18. Takeuchi M, Nishizaki Y, Sano O, Ohta T, Ikeda M, Kurimoto M. Immunohistochemical and immuno-electron-microscopic detection of interferon-g-inducing factor ("Interleukin-18") in mouse intestinal epithelial cells. Cell Tissue Res 1997;289:499-503.
19. Micallef MJ, Ohtsuki T, Kohno K, Tanabe F, Ushio S, Namba M, et al. Interferon-γ-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for IFN-γ production. Eur J Immunol 1996;26:1647-51.
20. Ahn H-J, Maruo S, Tomura M, Mu J, Hamaoka T, Nakanishi K, et al. A mechanism underlying synergy between IL-12 and IFNγ-inducing factor in enhanced production of IFN-γ. J Immunol 1997;159:2125-31.
21. Tsutsui H, Nakanishi K, Matsui K, Higashino K, Okamura H, Miyazawa Y, et al. IFN-γ-inducing faclor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones. J Immunol 1996;157:3967-73.
22. Hofstra CL, Van Ark I, Hofman G, Kool M, Nijkamp FP, Van Oosterhout AJ. Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels. J Immunol 1998;161:5054-60.
23. Mosmann TR, Coffman RT. Two types of mouse helper T cell clone: implications for immune regulation. Immunol Today 1987;8:223-7.
24. Sagara H, Matsuda H, Wada N, Yagita H, Fukuda T, Okumura K, et al. A monoclonal antibody against very late activation antigen-4 inhibits eosinophil accumulation and late asthmatic response in a guinea pig model of asthma. Int Arch Allergy Immunol 1997;112:287-94.
25. Iwamoto T, Takatsu K. Evaluation of airway hyperreactivity in interleukin-5 transgenic mice. Int Arch Allergy Immunol 1995;108(Suppl 1):28-30.
26. Lefort J, Bachelet C-M, Leduc D, Vargaftig BB. Effect of antigen provocation of IL-S transgenic mice on eosinophil mobilization and bronchial hyperresponsiveness. J Allergy Clin Immunol 1996;97:788-99.
27. Corry DB, Folkesson HG, Warnock ML, Erie DJ, Matthay MA, Wiener-Kronish JP, et al. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996;183:109-17.
28. Mehlhop PD, Van de Rijn M, Goldberg AB, Brewer JP, Kurup VP, Martin TR, et al. Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma. Proc Natl Acad Sci USA 1997;94:1344-9.
29. Hamelmann E, Vella AT, Oshiba A, Kappler JW, Marrack P, Gelfand EW. Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc Natl Acad Sci USA 1997;94:1350-5.
30. Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999;103:175-83.
31. Gavett SH, O'Hearn DJ, Li X, Huang S-K, Finkelman FD, Willa-Karp M. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med 1995;182:1527-36.
32. Dao T, Ohashi K, Kayano T, Kurimoto M, Okamura H. Interferon-γ inducing factor, a novel cytokine, enhances Fas ligand-mediated cytotoxicity of murine T helper 1 cells. Cell Immunol 1996;173:230-5.
33. Miyawaki T, Uehara T, Nibu R, Tsuji T, Yachie A, Yonehara S, et al. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulation in human peripheral blood. J Immunol 1992;149:3753-8.
34. Druihe A, Cai Z, Haile S, Chouaib S, Pretolani M. Fas-mediated apoptosis in cultured human eosinophils. Blood 1996;87:2822-30.
35. Tsuyuki S, Bertrand C, Erard F, Trifilieff A, Tsuyuki J, Wesp M, et al. Activation of the Fas receptor on lung eosinophils leads to apoptosis and resolution of eosinophilic inflammation of the airways. J Clin Invest 1995;96:2924-31.
36. Matsumoto K, Schleimer RP, Saito H, Iikura Y, Bochner BS. Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro. Blood 1995;86:1437-43.
37. Yamaguchi Y, Suda T, Ohta S, Tominaga K, Miura Y, Kasahara T. Analysis of the survival of mature human eosinophils: Interleukin-5 prevents apoptosis in mature human eosinophils. Blood 1991;78:2542-7.
38. Her E, Frazer J, Austen KF, Ohen WF Jr. Eosinophil hematopoietins antagonize the programmed cell death of eosinophils. J Clin Invest 1991;88:1982-7.
39. Lopez AF, Sanderson CJ, Gamble JR, Campbell HD, Young IG, Vadas MA. Recombinant human Interleukin 5 is a selective activator of human eosinophil function. J Exp Med 1988;167:219-24.
40. Warren HS, Kinnear BF, Phillips JH, Lanier LL. Production of IL-5 by human NK cells and regulation of IL-5 secretion by IL-4, IL-10 and IL-12. J Immunol 1995;154:5144-52.
41. Warren HS, Kinnear BF, Kastelein RL, Lanier LL. Analysis of the costimulatory role of IL-2 and IL-15 in initiating proliferation of resting (CD56 dim) human NK cells. J Immunol 1996;156:3254-9.
42. Walker C, Checkel J, Cammisuli S, Leibson PJ, Gleich GJ. IL-5 production by NK cells contributes to eosinophil infiltration in a mouse model of allergic inflammation. J Immunol 1998;161:1962-9.
43. Walker C, Bode E, Boer L, Hansel TT, Blaser K, Virchow Jr J-C. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis 1992;146:109-15.