Differential effects of endogenous and exogenous interferon-γ on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma

American Journal of Respiratory Cell and Molecular Biology

Volumn 19, Issue 5, 1998, Pages 826-835

  Hofstra, Claudia L ^a   Van Ingrid, Ark ^b   Hofman, Gerard ^b   Nijkamp, Frans P ^b   Jardieu, Paula M ^b   Van Oosterhout, Antoon J M ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE;

CYTOKINE; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; IMMUNOGLOBULIN E; METHACHOLINE CHLORIDE; OVALBUMIN;

ANIMAL; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; FEMALE; HYPERSENSITIVITY; IMMUNOLOGY; INHALATIONAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKOCYTE; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LYMPH NODE; METABOLISM; MOUSE; MOUSE MUTANT; SPLEEN; T LYMPHOCYTE;

ADMINISTRATION, INHALATION; ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HYPERSENSITIVITY; IMMUNOGLOBULIN E; INJECTIONS, INTRAPERITONEAL; INTERFERON TYPE II; LEUKOCYTES; LYMPH NODES; MACROPHAGES, ALVEOLAR; METHACHOLINE CHLORIDE; MICE; MICE, KNOCKOUT; OVALBUMIN; SPLEEN; T-LYMPHOCYTES;

EID: 0032209767     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.19.5.3027     Document Type: Article

References (41)

1. Djukanovic, R., W. R. Roche, J. W. Wilson, C. R. W. Beasley, O. P. Twentyman, P. H. Howarth, and S. T. Holgate. 1990. Mucosal inflammation in asthma. Am. Rev. Respir. Dis. 142:434-457.
2. Robinson, D. S., Q. Hamid, S. Ying, A. Tsicopoulos, J. Barkans, A. M. Bentley, C. Corrigan, S. R. Durham, and A. B. Kay. 1992. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma, N. Engl. J. Med. 326:298-304.
3. Mosmann, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
4. Pene, J., F. Rousset, F. Briere, I. Chretien, J. Y. Bonnefoy, H. Spits, T. Yokota, N. Arai, K. I. Arai, J. Banchereau, and J. E. De Vries. 1988. IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2. Proc. Natl. Acad. Sci. USA 85:6880-6884.
5. Hessel, E. M., A. J. M. Van Oosterhout, I. Van Ark, B. Van Esch, G. Hofman, H. Van Loveren, H. F. J. Savelkoul, and F. P. Nijkamp. 1997. Development of airway hyperresponsiveness is dependent on IFNγ and independent of eosinophil infiltration. Am. J. Respir. Cell Mol. Biol. 16:325-334.
6. De Bie, J. J., E. M. Hessel, I. Van Ark, B. Van Esch, G. Hofman, F. P. Nijkamp, and A. J. M. Van Oosterhout. 1996. Effect of dexamethasone and endogenous corticosterone on airway hyperresponsiveness and eosinophilia in the mouse. Br. J. Pharmacol. 119:1484-1490.
7. Van Oosterhout, A. J. M., C. L. Hofstra, R. Shields, B. Chan, I. Van Ark, P. M. Jardieu, and F. P. Nijkamp. 1997. Murine CTLA4-IgG treatment inhibits airway eosinophilia, hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma. Am. J. Respir. Cell Mol. Biol. 17:386-392.
8. Dalton, D. K., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259:1739-1742.
9. + T cells produce Th2 type cytokines in a murine model of allergic asthma. Am. J. Respir. Crit. Care Med. 155:A735. (Abstr.)
10. Hessel, E. M., A. J. M. Van Oosterhout, C. L. Hofstra, J. J. De Bie, J. Garssen, H. Van Loveren, A. K. C. P. Verheyen, H. F. J. Savelkoul, and F. P. Nijkamp. 1995. Bronchoconstriction and airway hyperresponsiveness after ovalbumin inhalation in sensitized mice. Eur. J. Pharmacol. 293:401-412.
11. Raeburn, D., S. L. Underwood, and M. E. Villamil. 1992. Techniques for drug delivery to the airways, and assessment of lung function in animal models. J. Pharmacol. Toxicol. Methods 27:143-159.
12. Suda, T. S., R. J. Callahan, R. A. Wilkenson, N. Van Rooijen, and E. E. Schnecberger. 1996. Interferon-γ reduces Ia+ dendritic cell traffic to the lung. J. Leukoc, Biol. 60:519-527.
13. King, D. P., and P. P. Jones. 1983. Induction of Ia and H-2 antigens on a macrophage cell line by immune interferon. J. Immunol. 131:315-318.
14. Wong, G. H. W., I. Clark-Lewis, A. W. Harris, and J. W. Schrader. 1984. Effect of cloned interferon-gamma on expression of H-2 and Ia antigens on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin. Eur. J. Immunol. 14:52-56.
15. Punnonen, J., G. Aversa, B. G. Cocks, and J. F. De Vries. 1994. Role of interleukin-4 and interleukin-13 in synthesis and expression of CD23 by human B cells. Allergy 49:576-586.
16. Kroegel, C., J. C. Virchow, W. Luttmann, C. Walker, and J. A. Warner. 1994. Pulmonary immune cells in health und disease: 1. The eosinophil leucocyte. Eur. Respir. J. 7:519-543.
17. Coyle, A. J., S. Tsuyuki, C. Bertrand, S. Huang, M. Aguet, S. S. Alkan, and G. P. Anderson. 1996. Mice lacking the IFN-γ receptor have an impaired ability to resolve a lung eosinophilic inflammatory response associated with a prolonged capacity of T cells to exhibit a Th2 cytokine profile. J. Immunol. 156:2680-2685.
18. Gauchat, J.-F., D. A. Lebman, R. L. Coffman, H. Gascan, and J. E. De Vries. 1990. Structure and expression of germline Î transcripts in human B cells induced by interleukin 4 to switch to IgE production. J. Exp. Med. 172:463-473.
19. Bradding, P., J. A. Roberts, K. M. Britten, S. Montefort, R. Djukanovic, R. Mueller, C. H. Heusser, P. H. Howart, and S. T. Holgate. 1994. Interleukin-4, -5 and -6 and tumor necrosis factor-α in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am. J. Respir. Cell Mol. Biol. 10:471-480.
20. Takagi, M., K. Koike, and T. Nakahata, 1990. Antiproliferative effect of IFN-γ on proliferation of mouse connective tissue-type mast cells. J. Immunol. 145:1880-1884.
21. Nafziger, J., M. Arock, J.-J. Guillosson, and J. Wietzerbin. 1990. Specific high-affinity receptors for interferon-γ on mouse bone marrow-derived mast cells: inhibitory effect of interferon-γ on mast cell precursors. Eur. J. Immunol. 20:113-117.
22. Chvatchko, Y., M. H. Kosco-Vilbois, S. Herren, J. Lefort, and J.-Y. Bonnefoy. 1996. Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge. J. Exp. Med. 184:2353-2360.
23. Lack, G., H. Renz, J. Saloga, K. L. Bradley, J. Loader, D. Y. M. Leung, G. Larsen, and E. W. Gelfand. 1994. Nebulized but not parenteral IFN-γ decreases IgE production and normalizes airways function in a murine model of allergen sensitization. J. Immunol. 152:2546-2554.
24. Lack, G., K. L. Bradley, E. Hamelmann, H. Renz, J. Loader, D. Y. M. Leung, G. Larsen, and E. W. Gelfand. 1996. Nebulized IFN-γ inhibits the development of secondary allergic responses in mice. J. Immunol. 157:1432-1439.
25. Barnes, P. J., and F. Y. Liew. 1995. Nitric oxide and asthmatic inflammation. Immunol. Today 16:128-130.
26. Hogman, M., C. G. Frostell, H. Hedenstrom, and G. Hedenstiera. 1993. Inhalation of nitric oxide modulates adult bronchial tone. Am. Rev. Respir. Dis. 148:1474-1478.
27. Nijkamp, F. P., H. J. Van Der Linde, and G. Folkerts. 1993. Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Role of the epithelium. Am. Rev. Respir. Dis. 148:727-734.
28. Nagai, H., Y. Maeda, and H. Tanaka. 1997. The effect of anti-IL-4 monoclonal antibody, rapamycin and interferon-gamma on airway hyperreactivity to acetylcholine in mice. Clin Exp. Allergy 27:218-224.
29. Nijkamp, F. P., and G. Folkerts. 1997. Nitric oxide: initiator and modulator. Clin. Exp. Allergy 27:347-350.
30. Nortamo, P., R. Li, R. Renkonen, T. Timonen, J. Prieto, M. Patarroyo, and C. G. Gahmberg. 1991. The expression of human intercellular adhesion molecule-2 is refractory to inflammatory cytokines. Eur. J. Immunol. 21: 2629-2632.
31. Pober, J. S., and R. S. Cotran. 1990. The role of endothelial cells in inflammation. Transplantation 50:537-544.
32. Wegner, C. D., R. H. Gundel, P. Reilly, N. Haynes, L. G. Letts, and R. Rothlein. 1990. Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma. Science 247:456-459.
33. Valerius, T., R. Repp, J. R. Kalden, and E. Platzer. 1990. Effects of IFN on human eosinophils in comparison with other cytokines. A novel class of eosinophil activators with delayed onset of action. J. Immunol. 145:2950-2958.
34. Feder, L. S., D. Stelts, R. W. Chapman, D. Manfra, Y. Crawley, H. Jones, M. Minnicozzi, X. Fernandez, T. Paster, R. W. Egan, W. Kreutner, and T. T. Kung. 1997. Role of nitric oxide on eosinophilic lung inflammation in allergic mice. Am. J. Respir. Cell Mol. Biol. 17:436-442.
35. Nakajima, H., I. Iwamoto, and S. Yoshida. 1993. Aerosolized recombinant interferon-γ prevents antigen-induced eosinophil recruitment in mouse trachea. Am. Rev. Respir. Dis. 148:1102-1104.
36. Kung, T. T., D. M. Stells, J. A. Zurcher, H. Jones, S. P. Umland, R. W. Egan, W. Kreutner, and R. W. Chapman. 1995. Interferon-γ and antibodies to interleukin-5 and interleukin-4 inhibit pulmonary eosinophilia in allergic mice. Inflamm. Res. 44(Suppl. 2):S185-S186.
37. + T cells. J. Exp. Med. 177:573-576.
38. Kung, T. T., D. Stelts, J. A. Zurcher, A. S. Watnick, H. Jones, P. J. Mauser, X. Fernandez, S. Umland, W. Kreutner, R. W. Chapman, and R. W. Egan. 1994. Mechanisms of allergic pulmonary eosinophilia in the mouse. J. Allergy Clin. Immunol. 94:1217-1224.
39. Kips, J. C., G. G. Brusselle, R. A. Peleman, G. F. Joos, and R. A. Pauwels. 1995. Inhibition of the allergen induced eosinophil influx in murine airways by IL-12 is not mediated through IFN-γ. Am. J. Respir. Crit. Care Med. 151:A826. (Abstr.)
40. Corry, D. B., H. G. Folkesson, M. L. Warnock, D. J. Erle, M. A. Matthay, J. P. Wiener-Kronish, and R. M. Locksley. 1996. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperresponsiveness. J. Exp. Med. 183:109-117.
41. Nagai, H., S. Yamaguchi, N. Inagaki, N. Tsuruoka, Y. Hitoshi, and K. Takatsu. 1993. Effect of anti-IL-5 monoclonal antibody on allergic bronchial eosinophilia and airway hyperresponsiveness in mice. Life Sci. 53: PL243-PL247.