-
1
-
-
0034446569
-
Mutant T cell lines as model systems for the dissection of T cell antigen receptor signaling pathways
-
R.T. Abraham Mutant T cell lines as model systems for the dissection of T cell antigen receptor signaling pathways Immunol. Res. 22 2000 95-117
-
(2000)
Immunol. Res.
, vol.22
, pp. 95-117
-
-
Abraham, R.T.1
-
2
-
-
12344328544
-
Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells
-
A.L. Ackerman C. Kyritsis R. Tampe P. Cresswell Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells Nat. Immunol. 6 2005 107-113
-
(2005)
Nat. Immunol.
, vol.6
, pp. 107-113
-
-
Ackerman, A.L.1
Kyritsis, C.2
Tampe, R.3
Cresswell, P.4
-
3
-
-
0347505003
-
CD28-mediated co-stimulation: A quantitative support for TCR signalling
-
O. Acuto F. Michel CD28-mediated co-stimulation: A quantitative support for TCR signalling Nat. Rev. Immunol. 3 2003 939-951
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 939-951
-
-
Acuto, O.1
Michel, F.2
-
5
-
-
0033082989
-
Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands
-
S.M. Alam G.M. Davies C.M. Lin T. Zal W. Nasholds S.C. Jameson K.A. Hogquist N.R. Gascoigne P.J. Travers Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands Immunity 10 1999 227-237
-
(1999)
Immunity
, vol.10
, pp. 227-237
-
-
Alam, S.M.1
Davies, G.M.2
Lin, C.M.3
Zal, T.4
Nasholds, W.5
Jameson, S.C.6
Hogquist, K.A.7
Gascoigne, N.R.8
Travers, P.J.9
-
7
-
-
0033735397
-
Internalization and intracellular fate of TCR-CD3 complexes
-
A. Alcover B. Alarcon Internalization and intracellular fate of TCR-CD3 complexes Crit. Rev. Immunol. 20 2000 325-346
-
(2000)
Crit. Rev. Immunol.
, vol.20
, pp. 325-346
-
-
Alcover, A.1
Alarcon, B.2
-
8
-
-
0034680105
-
Progression of autoimmune diabetes driven by avidity maturation of a T-cell population
-
A. Amrani J. Verdaguer P. Serra S. Tafuro R. Tan P. Santamaria Progression of autoimmune diabetes driven by avidity maturation of a T-cell population Nature 406 2000 739-742
-
(2000)
Nature
, vol.406
, pp. 739-742
-
-
Amrani, A.1
Verdaguer, J.2
Serra, P.3
Tafuro, S.4
Tan, R.5
Santamaria, P.6
-
9
-
-
0035823601
-
Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens
-
P.S. Andersen C. Geisler S. Buus R.A. Mariuzza K. Karjalainen Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens J. Biol. Chem. 276 2001 33452-33457
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33452-33457
-
-
Andersen, P.S.1
Geisler, C.2
Buus, S.3
Mariuzza, R.A.4
Karjalainen, K.5
-
10
-
-
7244219942
-
Early cytoskeletal rearrangement during dendritic cell maturation enhances synapse formation and Ca(2+) signaling in CD8(+) T cells
-
M. Averbeck T. Braun G. Pfeifer J. Sleeman J. Dudda S.F. Martin B. Kremer K. Aktories J.C. Simon C. Termeer Early cytoskeletal rearrangement during dendritic cell maturation enhances synapse formation and Ca(2+) signaling in CD8(+) T cells Eur. J. Immunol. 34 2004 2708-2719
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2708-2719
-
-
Averbeck, M.1
Braun, T.2
Pfeifer, G.3
Sleeman, J.4
Dudda, J.5
Martin, S.F.6
Kremer, B.7
Aktories, K.8
Simon, J.C.9
Termeer, C.10
-
11
-
-
0029810397
-
Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface
-
C. Beeson J. Rabinowitz K. Tate I. Gutgemann Y.H. Chien P.P. Jones M.M. Davis H.M. McConnell Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface J. Exp. Med. 184 1996 777-782
-
(1996)
J. Exp. Med.
, vol.184
, pp. 777-782
-
-
Beeson, C.1
Rabinowitz, J.2
Tate, K.3
Gutgemann, I.4
Chien, Y.H.5
Jones, P.P.6
Davis, M.M.7
McConnell, H.M.8
-
12
-
-
0030890603
-
Mouse CD1-specific NK1T cells: Development, specificity, and function
-
A. Bendelac M.N. Rivera S.H. Park J.H. Roark Mouse CD1-specific NK1 T cells: Development, specificity, and function Annu. Rev. Immunol. 15 1997 535-562
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 535-562
-
-
Bendelac, A.1
Rivera, M.N.2
Park, S.H.3
Roark, J.H.4
-
13
-
-
0024450056
-
Positive selection of the T cell repertoire: Where and when does it occur?
-
C. Benoist D. Mathis Positive selection of the T cell repertoire: Where and when does it occur? Cell 58 1989 1027-1033
-
(1989)
Cell
, vol.58
, pp. 1027-1033
-
-
Benoist, C.1
Mathis, D.2
-
14
-
-
0029935523
-
The structure of the T cell antigen receptor
-
G.A. Bentley R.A. Mariuzza The structure of the T cell antigen receptor Annu. Rev. Immunol. 14 1996 563-590
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 563-590
-
-
Bentley, G.A.1
Mariuzza, R.A.2
-
15
-
-
0032530696
-
Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes
-
N.N. Berg L.G. Puente W. Dawicki H.L. Ostergaard Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes J. Immunol. 161 1998 2919-2924
-
(1998)
J. Immunol.
, vol.161
, pp. 2919-2924
-
-
Berg, N.N.1
Puente, L.G.2
Dawicki, W.3
Ostergaard, H.L.4
-
16
-
-
0023902072
-
T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous alpha- and beta-genes
-
H. Bluthmann P. Kisielow Y. Uematsu M. Malissen P. Krimpenfort A. Berns H. von Boehmer M. Steinmetz T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous alpha- and beta-genes Nature 334 1988 156-159
-
(1988)
Nature
, vol.334
, pp. 156-159
-
-
Bluthmann, H.1
Kisielow, P.2
Uematsu, Y.3
Malissen, M.4
Krimpenfort, P.5
Berns, A.6
von Boehmer, H.7
Steinmetz, M.8
-
17
-
-
0037077280
-
Serial triggering of T cell receptors results in incremental accumulation of signaling intermediates
-
Z. Borovsky G. Mishan-Eisenberg E. Yaniv J. Rachmilewitz Serial triggering of T cell receptors results in incremental accumulation of signaling intermediates J. Biol. Chem. 277 2002 21529-21536
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21529-21536
-
-
Borovsky, Z.1
Mishan-Eisenberg, G.2
Yaniv, E.3
Rachmilewitz, J.4
-
18
-
-
0025301875
-
Signal transduction through the T cell receptor-CD3 complex. Evidence for heterogeneity in receptor coupling
-
G. Brattsand D.A. Cantrell S. Ward F. Ivars M. Gullberg Signal transduction through the T cell receptor-CD3 complex. Evidence for heterogeneity in receptor coupling J. Immunol. 144 1990 3651-3658
-
(1990)
J. Immunol.
, vol.144
, pp. 3651-3658
-
-
Brattsand, G.1
Cantrell, D.A.2
Ward, S.3
Ivars, F.4
Gullberg, M.5
-
19
-
-
2542448243
-
CD1: Antigen presentation and T cell function
-
M. Brigl M.B. Brenner CD1: Antigen presentation and T cell function Annu. Rev. Immunol. 22 2004 817-890
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 817-890
-
-
Brigl, M.1
Brenner, M.B.2
-
22
-
-
0033557173
-
T cell affinity maturation by selective expansion during infection
-
D.H. Busch E.G. Pamer T cell affinity maturation by selective expansion during infection J. Exp. Med. 189 1999 701-710
-
(1999)
J. Exp. Med.
, vol.189
, pp. 701-710
-
-
Busch, D.H.1
Pamer, E.G.2
-
23
-
-
0029874657
-
T cell antigen receptor signal transduction pathways
-
D. Cantrell T cell antigen receptor signal transduction pathways Annu. Rev. Immunol. 14 1996 259-274
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 259-274
-
-
Cantrell, D.1
-
24
-
-
0025942245
-
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein
-
A.C. Chan B.A. Irving J.D. Fraser A. Weiss The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein Proc. Natl. Acad. Sci. USA 88 1991 9166-9170
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9166-9170
-
-
Chan, A.C.1
Irving, B.A.2
Fraser, J.D.3
Weiss, A.4
-
25
-
-
0026483786
-
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
-
A.C. Chan M. Iwashima C.W. Turck A. Weiss ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR zeta chain Cell 71 1992 649-662
-
(1992)
Cell
, vol.71
, pp. 649-662
-
-
Chan, A.C.1
Iwashima, M.2
Turck, C.W.3
Weiss, A.4
-
27
-
-
2642648459
-
The outline structure of the T-cell alpha beta receptor
-
C. Chothia D.R. Boswell A.M. Lesk The outline structure of the T-cell alpha beta receptor EMBO J 7 1988 3745-3755
-
(1988)
EMBO J
, vol.7
, pp. 3745-3755
-
-
Chothia, C.1
Boswell, D.R.2
Lesk, A.M.3
-
29
-
-
0020420130
-
The regulation of T cell growth: Requirements for the activation and replication of antigen-specific interleukin 2 producing T cells
-
R.B. Corley The regulation of T cell growth: Requirements for the activation and replication of antigen-specific interleukin 2 producing T cells Immunobiology 163 1982 63-76
-
(1982)
Immunobiology
, vol.163
, pp. 63-76
-
-
Corley, R.B.1
-
30
-
-
0034677055
-
Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
-
M.A. Daniels S.C. Jameson Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers J. Exp. Med. 191 2000 335-346
-
(2000)
J. Exp. Med.
, vol.191
, pp. 335-346
-
-
Daniels, M.A.1
Jameson, S.C.2
-
31
-
-
0023720148
-
T-cell antigen receptor genes and T-cell recognition
-
M.M. Davis P.J. Bjorkman T-cell antigen receptor genes and T-cell recognition Nature 334 1988 395-402
-
(1988)
Nature
, vol.334
, pp. 395-402
-
-
Davis, M.M.1
Bjorkman, P.J.2
-
32
-
-
2342566929
-
What is the importance of the immunological synapse?
-
D.M. Davis M.L. Dustin What is the importance of the immunological synapse? Trends Immunol. 25 2004 323-327
-
(2004)
Trends Immunol.
, vol.25
, pp. 323-327
-
-
Davis, D.M.1
Dustin, M.L.2
-
34
-
-
0043268924
-
Dynamics of cell surface molecules during T cell recognition
-
M.M. Davis M. Krogsgaard J.B. Huppa C. Sumen M.A. Purbhoo D.J. Irvine L.C. Wu L. Ehrlich Dynamics of cell surface molecules during T cell recognition Annu. Rev. Biochem. 72 2003 717-742
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 717-742
-
-
Davis, M.M.1
Krogsgaard, M.2
Huppa, J.B.3
Sumen, C.4
Purbhoo, M.A.5
Irvine, D.J.6
Wu, L.C.7
Ehrlich, L.8
-
36
-
-
0032152437
-
Contribution of mass spectrometry to contemporary immunology
-
A. de Jong Contribution of mass spectrometry to contemporary immunology Mass Spectrom. Rev. 17 1998 311-335
-
(1998)
Mass Spectrom. Rev.
, vol.17
, pp. 311-335
-
-
de Jong, A.1
-
37
-
-
0035652354
-
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin
-
J. Delon K. Kaibuchi R.N. Germain Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin Immunity 15 2001 691-701
-
(2001)
Immunity
, vol.15
, pp. 691-701
-
-
Delon, J.1
Kaibuchi, K.2
Germain, R.N.3
-
38
-
-
0025182003
-
The minimal number of class II MHC-antigen complexes needed for T cell activation
-
S. Demotz H.M. Grey A. Sette The minimal number of class II MHC-antigen complexes needed for T cell activation Science 249 1990 1028-1030
-
(1990)
Science
, vol.249
, pp. 1028-1030
-
-
Demotz, S.1
Grey, H.M.2
Sette, A.3
-
39
-
-
0032483559
-
A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts
-
M.L. Dustin M.W. Olszowy A.D. Holdorf J. Li S. Bromley N. Desai P. Widder F. Rosenberger P.A. van der Merwe P.M. Allen A.S. Shaw A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts Cell 94 1998 667-677
-
(1998)
Cell
, vol.94
, pp. 667-677
-
-
Dustin, M.L.1
Olszowy, M.W.2
Holdorf, A.D.3
Li, J.4
Bromley, S.5
Desai, N.6
Widder, P.7
Rosenberger, F.8
van der Merwe, P.A.9
Allen, P.M.10
Shaw, A.S.11
-
40
-
-
0036858973
-
Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: Crucial role of interaction kinetics on functional outcomes
-
V. Dutoit P. Guillaume J.C. Cerottini P. Romero D. Valmori Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: Crucial role of interaction kinetics on functional outcomes Eur. J. Immunol. 32 2002 3285-3293
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 3285-3293
-
-
Dutoit, V.1
Guillaume, P.2
Cerottini, J.C.3
Romero, P.4
Valmori, D.5
-
41
-
-
0028951561
-
A signal strength hypothesis of thymic selection: Preliminary considerations
-
K. Eichmann A signal strength hypothesis of thymic selection: preliminary considerations Immunol. Lett. 44 1995 87-90
-
(1995)
Immunol. Lett.
, vol.44
, pp. 87-90
-
-
Eichmann, K.1
-
42
-
-
0029805829
-
Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins
-
H.N. Eisen Y. Sykulev T.J. Tsomides Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins Adv. Protein Chem. 49 1996 1-56
-
(1996)
Adv. Protein Chem.
, vol.49
, pp. 1-56
-
-
Eisen, H.N.1
Sykulev, Y.2
Tsomides, T.J.3
-
43
-
-
0025855156
-
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
-
K. Falk O. Rotzschke S. Stevanovic G. Jung H.G. Rammensee Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules Nature 351 1991 290-296
-
(1991)
Nature
, vol.351
, pp. 290-296
-
-
Falk, K.1
Rotzschke, O.2
Stevanovic, S.3
Jung, G.4
Rammensee, H.G.5
-
45
-
-
1242338137
-
Degenerate recognition of T cell epitopes: Impact of T cell receptor reserve and stability of peptide: MHC complexes
-
M.L. Ford B.D. Evavold Degenerate recognition of T cell epitopes: Impact of T cell receptor reserve and stability of peptide: MHC complexes Mol. Immunol. 40 2004 1019-1025
-
(2004)
Mol. Immunol.
, vol.40
, pp. 1019-1025
-
-
Ford, M.L.1
Evavold, B.D.2
-
46
-
-
0027509812
-
Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential
-
D. Fowell D. Mason Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential J. Exp. Med. 177 1993 627-636
-
(1993)
J. Exp. Med.
, vol.177
, pp. 627-636
-
-
Fowell, D.1
Mason, D.2
-
47
-
-
0036696998
-
TCR triggering on the move: Diversity of T-cell interactions with antigen-presenting cells
-
P. Friedl E.B. Brocker TCR triggering on the move: Diversity of T-cell interactions with antigen-presenting cells Immunol. Rev. 186 2002 83-89
-
(2002)
Immunol. Rev.
, vol.186
, pp. 83-89
-
-
Friedl, P.1
Brocker, E.B.2
-
48
-
-
2942659074
-
T cell receptor-ligand interactions: A conformational preequilibrium or an induced fit
-
D.M. Gakamsky I.F. Luescher I. Pecht T cell receptor-ligand interactions: A conformational preequilibrium or an induced fit Proc. Natl. Acad. Sci. USA 101 2004 9063-9066
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9063-9066
-
-
Gakamsky, D.M.1
Luescher, I.F.2
Pecht, I.3
-
50
-
-
85012563943
-
T-cell receptor binding kinetics in T-cell development and activation
-
N.R. Gascoigne T. Zal S.M. Alam T-cell receptor binding kinetics in T-cell development and activation Expert Rev. Mol. Med. 2001 2001 1-17
-
(2001)
Expert Rev. Mol. Med.
, vol.2001
, pp. 1-17
-
-
Gascoigne, N.R.1
Zal, T.2
Alam, S.M.3
-
51
-
-
0032968708
-
The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation
-
R.N. Germain I. Stefanova The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation Annu. Rev. Immunol. 17 1999 467-522
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 467-522
-
-
Germain, R.N.1
Stefanova, I.2
-
53
-
-
14244262563
-
T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes
-
D. Gil A.G. Schrum B. Alarcon E. Palmer T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes J. Exp. Med. 201 2005 517-522
-
(2005)
J. Exp. Med.
, vol.201
, pp. 517-522
-
-
Gil, D.1
Schrum, A.G.2
Alarcon, B.3
Palmer, E.4
-
54
-
-
0033581935
-
Selecting and maintaining a diverse T-cell repertoire
-
A.W. Goldrath M.J. Bevan Selecting and maintaining a diverse T-cell repertoire Nature 402 1999 255-262
-
(1999)
Nature
, vol.402
, pp. 255-262
-
-
Goldrath, A.W.1
Bevan, M.J.2
-
55
-
-
16344370564
-
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell
-
P.A. Gonzalez L.J. Carreno D. Coombs J.E. Mora E. Palmieri B. Goldstein S.G. Nathenson A.M. Kalergis T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell Proc. Natl. Acad. Sci. USA 102 2005 4824-4829
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4824-4829
-
-
Gonzalez, P.A.1
Carreno, L.J.2
Coombs, D.3
Mora, J.E.4
Palmieri, E.5
Goldstein, B.6
Nathenson, S.G.7
Kalergis, A.M.8
-
57
-
-
0031944607
-
CD40 and CD154 in cell-mediated immunity
-
I.S. Grewal R.A. Flavell CD40 and CD154 in cell-mediated immunity Annu. Rev. Immunol. 16 1998 111-135
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 111-135
-
-
Grewal, I.S.1
Flavell, R.A.2
-
59
-
-
0033666324
-
Antigen presentation in extracellular matrix: Interactions of T cells with dendritic cells are dynamic, short lived, and sequential
-
M. Gunzer A. Schafer S. Borgmann S. Grabbe K.S. Zanker E.B. Brocker E. Kampgen P. Friedl Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential Immunity 13 2000 323-332
-
(2000)
Immunity
, vol.13
, pp. 323-332
-
-
Gunzer, M.1
Schafer, A.2
Borgmann, S.3
Grabbe, S.4
Zanker, K.S.5
Brocker, E.B.6
Kampgen, E.7
Friedl, P.8
-
60
-
-
0025286210
-
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation
-
C.V. Harding E.R. Unanue Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation Nature 346 1990 574-576
-
(1990)
Nature
, vol.346
, pp. 574-576
-
-
Harding, C.V.1
Unanue, E.R.2
-
61
-
-
0026537347
-
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
-
F.A. Harding J.G. McArthur J.A. Gross D.H. Raulet J.P. Allison CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones Nature 356 1992 607-609
-
(1992)
Nature
, vol.356
, pp. 607-609
-
-
Harding, F.A.1
McArthur, J.G.2
Gross, J.A.3
Raulet, D.H.4
Allison, J.P.5
-
62
-
-
0032807417
-
The role of B7 costimulation in T-cell immunity
-
N.L. Harris F. Ronchese The role of B7 costimulation in T-cell immunity Immunol. Cell Biol. 77 1999 304-311
-
(1999)
Immunol. Cell Biol.
, vol.77
, pp. 304-311
-
-
Harris, N.L.1
Ronchese, F.2
-
63
-
-
0020623652
-
The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody
-
K. Haskins R. Kubo J. White M. Pigeon J. Kappler P. Marrack The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody J. Exp. Med. 157 1983 1149-1169
-
(1983)
J. Exp. Med.
, vol.157
, pp. 1149-1169
-
-
Haskins, K.1
Kubo, R.2
White, J.3
Pigeon, M.4
Kappler, J.5
Marrack, P.6
-
64
-
-
0037018102
-
Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRAß0101 and DRB1ß0401): Insight into TCR cross-restriction and alloreactivity
-
J. Hennecke D.C. Wiley Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRAß0101 and DRB1ß0401): Insight into TCR cross-restriction and alloreactivity J. Exp. Med. 195 2002 571-581
-
(2002)
J. Exp. Med.
, vol.195
, pp. 571-581
-
-
Hennecke, J.1
Wiley, D.C.2
-
65
-
-
0037331525
-
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
-
P.D. Holler D.M. Kranz Quantitative analysis of the contribution of TCR/ pepMHC affinity and CD8 to T cell activation Immunity 18 2003 255-264
-
(2003)
Immunity
, vol.18
, pp. 255-264
-
-
Holler, P.D.1
Kranz, D.M.2
-
66
-
-
0035887216
-
CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation
-
P.D. Holler A.R. Lim B.K. Cho L.A. Rund D.M. Kranz CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation J. Exp. Med. 194 2001 1043-1052
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1043-1052
-
-
Holler, P.D.1
Lim, A.R.2
Cho, B.K.3
Rund, L.A.4
Kranz, D.M.5
-
67
-
-
0032528403
-
The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement
-
D. Hudrisier B. Kessler S. Valitutti C. Horvath J.C. Cerottini I.F. Luescher The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement J. Immunol. 161 1998 553-562
-
(1998)
J. Immunol.
, vol.161
, pp. 553-562
-
-
Hudrisier, D.1
Kessler, B.2
Valitutti, S.3
Horvath, C.4
Cerottini, J.C.5
Luescher, I.F.6
-
68
-
-
0026507564
-
Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry
-
D.F. Hunt R.A. Henderson J. Shabanowitz K. Sakaguchi H. Michel N. Sevilir A.L. Cox E. Appella V.H. Engelhard Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry Science 255 1992 1261-1263
-
(1992)
Science
, vol.255
, pp. 1261-1263
-
-
Hunt, D.F.1
Henderson, R.A.2
Shabanowitz, J.3
Sakaguchi, K.4
Michel, H.5
Sevilir, N.6
Cox, A.L.7
Appella, E.8
Engelhard, V.H.9
-
69
-
-
0026664454
-
Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad
-
D.F. Hunt H. Michel T.A. Dickinson J. Shabanowitz A.L. Cox K. Sakaguchi E. Appella H.M. Grey A. Sette Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad Science 256 1992 1817-1820
-
(1992)
Science
, vol.256
, pp. 1817-1820
-
-
Hunt, D.F.1
Michel, H.2
Dickinson, T.A.3
Shabanowitz, J.4
Cox, A.L.5
Sakaguchi, K.6
Appella, E.7
Grey, H.M.8
Sette, A.9
-
70
-
-
0346244099
-
T-cell-antigen recognition and the immunological synapse
-
J.B. Huppa M.M. Davis T-cell-antigen recognition and the immunological synapse Nat. Rev. Immunol. 3 2003 973-983
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 973-983
-
-
Huppa, J.B.1
Davis, M.M.2
-
71
-
-
0041695164
-
Continuous T cell receptor signaling required for synapse maintenance and full effector potential
-
J.B. Huppa M. Gleimer C. Sumen M.M. Davis Continuous T cell receptor signaling required for synapse maintenance and full effector potential Nat. Immunol. 4 2003 749-755
-
(2003)
Nat. Immunol.
, vol.4
, pp. 749-755
-
-
Huppa, J.B.1
Gleimer, M.2
Sumen, C.3
Davis, M.M.4
-
72
-
-
0042090453
-
The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities
-
S.L. Hutchinson L. Wooldridge S. Tafuro B. Laugel M. Glick J.M. Boulter B.K. Jakobsen D.A. Price A.K. Sewell The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities J. Biol. Chem. 278 2003 24285-24293
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24285-24293
-
-
Hutchinson, S.L.1
Wooldridge, L.2
Tafuro, S.3
Laugel, B.4
Glick, M.5
Boulter, J.M.6
Jakobsen, B.K.7
Price, D.A.8
Sewell, A.K.9
-
73
-
-
0026064305
-
The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways
-
B.A. Irving A. Weiss The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways Cell 64 1991 891-901
-
(1991)
Cell
, vol.64
, pp. 891-901
-
-
Irving, B.A.1
Weiss, A.2
-
74
-
-
0027399703
-
Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain
-
B.A. Irving A.C. Chan A. Weiss Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain J. Exp. Med. 177 1993 1093-1103
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1093-1103
-
-
Irving, B.A.1
Chan, A.C.2
Weiss, A.3
-
75
-
-
0025057169
-
Sequence analysis of bovine T-cell receptor alpha chain
-
N. Ishiguro A. Tanaka M. Shinagawa Sequence analysis of bovine T-cell receptor alpha chain Immunogenetics 31 1990 57-60
-
(1990)
Immunogenetics
, vol.31
, pp. 57-60
-
-
Ishiguro, N.1
Tanaka, A.2
Shinagawa, M.3
-
76
-
-
0037306145
-
Kinetic perspectives of T cell antigen receptor signaling. A two-tier model for T cell full activation
-
M. Iwashima Kinetic perspectives of T cell antigen receptor signaling. A two-tier model for T cell full activation Immunol. Rev. 191 2003 196-210
-
(2003)
Immunol. Rev.
, vol.191
, pp. 196-210
-
-
Iwashima, M.1
-
78
-
-
0028406294
-
Thymic selection: Two pathways to life and two to death
-
C.A. Janeway Jr. Thymic selection: Two pathways to life and two to death Immunity 1 1994 3-6
-
(1994)
Immunity
, vol.1
, pp. 3-6
-
-
Janeway Jr., C.A.1
-
79
-
-
0035912764
-
How the immune system works to protect the host from infection: A personal view
-
C.A. Janeway Jr. How the immune system works to protect the host from infection: A personal view Proc. Natl. Acad. Sci. USA 98 2001 7461-7468
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7461-7468
-
-
Janeway Jr., C.A.1
-
80
-
-
0036181249
-
Viral persistance: HIV's strategies of immune system evasion
-
W.E. Johnson R.C. Desrosiers Viral persistance: HIV's strategies of immune system evasion Annu. Rev. Med. 53 2002 499-518
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 499-518
-
-
Johnson, W.E.1
Desrosiers, R.C.2
-
81
-
-
0033034333
-
Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: Association with disease progression
-
T. Kageshita S. Hirai T. Ono D.J. Hicklin S. Ferrone Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: association with disease progression Am. J. Pathol. 154 1999 745-754
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 745-754
-
-
Kageshita, T.1
Hirai, S.2
Ono, T.3
Hicklin, D.J.4
Ferrone, S.5
-
82
-
-
0037242815
-
Modulation of T cell immunity by TCR/pMHC dwell time and activating/ inhibitory receptor pairs on the antigen-presenting cell
-
A.M. Kalergis Modulation of T cell immunity by TCR/pMHC dwell time and activating/inhibitory receptor pairs on the antigen-presenting cell Curr. Pharm. Des. 9 2003 233-244
-
(2003)
Curr. Pharm. Des.
, vol.9
, pp. 233-244
-
-
Kalergis, A.M.1
-
83
-
-
0033951457
-
A simplified procedure for the preparation of MHC/peptide tetramers: Chemical biotinylation of an unpaired cysteine engineered at the C-terminus of MHC-I
-
A.M. Kalergis E.C. Goyarts E. Palmieri S. Honda W. Zhang S.G. Nathenson A simplified procedure for the preparation of MHC/peptide tetramers: chemical biotinylation of an unpaired cysteine engineered at the C-terminus of MHC-I J. Immunol. Methods 234 2000 61-70
-
(2000)
J. Immunol. Methods
, vol.234
, pp. 61-70
-
-
Kalergis, A.M.1
Goyarts, E.C.2
Palmieri, E.3
Honda, S.4
Zhang, W.5
Nathenson, S.G.6
-
84
-
-
0035286588
-
Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex
-
A.M. Kalergis N. Boucheron M.A. Doucey E. Palmieri E.C. Goyarts Z. Vegh I.F. Luescher S.G. Nathenson Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex Nat. Immunol. 2 2001 229-234
-
(2001)
Nat. Immunol.
, vol.2
, pp. 229-234
-
-
Kalergis, A.M.1
Boucheron, N.2
Doucey, M.A.3
Palmieri, E.4
Goyarts, E.C.5
Vegh, Z.6
Luescher, I.F.7
Nathenson, S.G.8
-
85
-
-
4644312322
-
LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo
-
S. Kandula C. Abraham LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo J. Immunol. 173 2004 4443-4451
-
(2004)
J. Immunol.
, vol.173
, pp. 4443-4451
-
-
Kandula, S.1
Abraham, C.2
-
86
-
-
0032438551
-
High- and low-potency ligands with similar affinities for the TCR: The importance of kinetics in TCR signaling
-
G.J. Kersh E.N. Kersh D.H. Fremont P.M. Allen High- and low-potency ligands with similar affinities for the TCR: The importance of kinetics in TCR signaling Immunity 9 1998 817-826
-
(1998)
Immunity
, vol.9
, pp. 817-826
-
-
Kersh, G.J.1
Kersh, E.N.2
Fremont, D.H.3
Allen, P.M.4
-
87
-
-
0031020465
-
Effects of epitope modification on T cell receptor-ligand binding and antigen recognition by seven H-2Kd-restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative
-
B.M. Kessler P. Bassanini J.C. Cerottini I.F. Luescher Effects of epitope modification on T cell receptor-ligand binding and antigen recognition by seven H-2Kd-restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative J. Exp. Med. 185 1997 629-640
-
(1997)
J. Exp. Med.
, vol.185
, pp. 629-640
-
-
Kessler, B.M.1
Bassanini, P.2
Cerottini, J.C.3
Luescher, I.F.4
-
88
-
-
0742305009
-
Linking molecular and cellular events in T-cell activation and synapse formation
-
M. Krogsgaard J.B. Huppa M.A. Purbhoo M.M. Davis Linking molecular and cellular events in T-cell activation and synapse formation Sem. Immunol. 15 2003 307-315
-
(2003)
Sem. Immunol.
, vol.15
, pp. 307-315
-
-
Krogsgaard, M.1
Huppa, J.B.2
Purbhoo, M.A.3
Davis, M.M.4
-
89
-
-
0348047600
-
Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation
-
M. Krogsgaard N. Prado E.J. Adams X.L. He D.C. Chow D.B. Wilson K.C. Garcia M.M. Davis Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation Mol. Cell 12 2003 1367-1378
-
(2003)
Mol. Cell
, vol.12
, pp. 1367-1378
-
-
Krogsgaard, M.1
Prado, N.2
Adams, E.J.3
He, X.L.4
Chow, D.C.5
Wilson, D.B.6
Garcia, K.C.7
Davis, M.M.8
-
90
-
-
17144374753
-
Toward an understanding of NKT cell biology: Progress and paradoxes
-
M. Kronenberg Toward an understanding of NKT cell biology: Progress and paradoxes Annu. Rev. Immunol. 23 2005 877-900
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 877-900
-
-
Kronenberg, M.1
-
91
-
-
0035377009
-
Antigen decoding by T lymphocytes: From synapses to fate determination
-
A. Lanzavecchia F. Sallusto Antigen decoding by T lymphocytes: From synapses to fate determination Nat. Immunol. 2 2001 487-492
-
(2001)
Nat. Immunol.
, vol.2
, pp. 487-492
-
-
Lanzavecchia, A.1
Sallusto, F.2
-
92
-
-
0033534678
-
From TCR engagement to T cell activation: A kinetic view of T cell behavior
-
A. Lanzavecchia G. Lezzi A. Viola From TCR engagement to T cell activation: A kinetic view of T cell behavior Cell 96 1999 1-4
-
(1999)
Cell
, vol.96
, pp. 1-4
-
-
Lanzavecchia, A.1
Lezzi, G.2
Viola, A.3
-
93
-
-
2442597075
-
Thymic expression of a gastritogenic epitope results in positive selection of self-reactive pathogenic T cells
-
K.L. Laurie N.L. La Gruta N. Koch I.R. van Driel P.A. Gleeson Thymic expression of a gastritogenic epitope results in positive selection of self-reactive pathogenic T cells J. Immunol. 172 2004 5994-6002
-
(2004)
J. Immunol.
, vol.172
, pp. 5994-6002
-
-
Laurie, K.L.1
La Gruta, N.L.2
Koch, N.3
van Driel, I.R.4
Gleeson, P.A.5
-
95
-
-
0036776238
-
Correlation of a dynamic model for immunological synapse formation with effector functions: Two pathways to synapse formation
-
S.J. Lee Y. Hori J.T. Groves M.L. Dustin A.K. Chakraborty Correlation of a dynamic model for immunological synapse formation with effector functions: Two pathways to synapse formation Trends Immunol. 23 2002a 492-499
-
(2002)
Trends Immunol.
, vol.23
, pp. 492-499
-
-
Lee, S.J.1
Hori, Y.2
Groves, J.T.3
Dustin, M.L.4
Chakraborty, A.K.5
-
97
-
-
0034624809
-
Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes
-
O. Leupin R. Zaru T. Laroche S. Muller S. Valitutti Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes Curr. Biol. 10 2000 277-280
-
(2000)
Curr. Biol.
, vol.10
, pp. 277-280
-
-
Leupin, O.1
Zaru, R.2
Laroche, T.3
Muller, S.4
Valitutti, S.5
-
98
-
-
0035046094
-
Viral immune evasion strategies and the underlying cell biology
-
M.E. Lorenzo H.L. Ploegh R.S. Tirabassi Viral immune evasion strategies and the underlying cell biology Sem. Immunol. 13 2001 1-9
-
(2001)
Sem. Immunol.
, vol.13
, pp. 1-9
-
-
Lorenzo, M.E.1
Ploegh, H.L.2
Tirabassi, R.S.3
-
99
-
-
0036533422
-
Development and selection of NKT cells
-
H.R. MacDonald Development and selection of NKT cells Curr. Opin. Immunol. 14 2002 250-254
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 250-254
-
-
MacDonald, H.R.1
-
100
-
-
0035500758
-
Duration and strength of extracellular signal-regulated kinase signals are altered during positive versus negative thymocyte selection
-
S. Mariathasan A. Zakarian D. Bouchard A.M. Michie J.C. Zuniga-Pflucker P.S. Ohashi Duration and strength of extracellular signal-regulated kinase signals are altered during positive versus negative thymocyte selection J. Immunol. 167 2001 4966-4973
-
(2001)
J. Immunol.
, vol.167
, pp. 4966-4973
-
-
Mariathasan, S.1
Zakarian, A.2
Bouchard, D.3
Michie, A.M.4
Zuniga-Pflucker, J.C.5
Ohashi, P.S.6
-
101
-
-
0028589333
-
Kinetics of T-cell receptor binding to peptide/I-Ek complexes: Correlation of the dissociation rate with T-cell responsiveness
-
K. Matsui J.J. Boniface P. Steffner P.A. Reay M.M. Davis Kinetics of T-cell receptor binding to peptide/I-Ek complexes: Correlation of the dissociation rate with T-cell responsiveness Proc. Natl. Acad. Sci. USA 91 1994 12862-12866
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12862-12866
-
-
Matsui, K.1
Boniface, J.J.2
Steffner, P.3
Reay, P.A.4
Davis, M.M.5
-
102
-
-
12344298492
-
Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes
-
N. McCarty S. Paust K. Ikizawa I. Dan X. Li H. Cantor Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes Nat. Immunol. 6 2005 65-72
-
(2005)
Nat. Immunol.
, vol.6
, pp. 65-72
-
-
McCarty, N.1
Paust, S.2
Ikizawa, K.3
Dan, I.4
Li, X.5
Cantor, H.6
-
103
-
-
0020593643
-
The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by xenoantiserum
-
B.W. McIntyre J.P. Allison The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by xenoantiserum Cell 34 1983 739-746
-
(1983)
Cell
, vol.34
, pp. 739-746
-
-
McIntyre, B.W.1
Allison, J.P.2
-
104
-
-
0029063148
-
Kinetic proofreading in T-cell receptor signal transduction
-
T.W. McKeithan Kinetic proofreading in T-cell receptor signal transduction Proc. Natl. Acad. Sci. USA 92 1995 5042-5046
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5042-5046
-
-
McKeithan, T.W.1
-
105
-
-
5444229324
-
Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes
-
M.J. Miller O. Safrina I. Parker M.D. Cahalan Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes J. Exp. Med. 200 2004 847-856
-
(2004)
J. Exp. Med.
, vol.200
, pp. 847-856
-
-
Miller, M.J.1
Safrina, O.2
Parker, I.3
Cahalan, M.D.4
-
106
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
C.R. Monks B.A. Freiberg H. Kupfer N. Sciaky A. Kupfer Three-dimensional segregation of supramolecular activation clusters in T cells Nature 395 1998 82-86
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
107
-
-
0022568243
-
Murine major histocompatibility complex class-I mutants: Molecular analysis and structure-function implications
-
S.G. Nathenson J. Geliebter G.M. Pfaffenbach R.A. Zeff Murine major histocompatibility complex class-I mutants: Molecular analysis and structure-function implications Annu. Rev. Immunol. 4 1986 471-502
-
(1986)
Annu. Rev. Immunol.
, vol.4
, pp. 471-502
-
-
Nathenson, S.G.1
Geliebter, J.2
Pfaffenbach, G.M.3
Zeff, R.A.4
-
108
-
-
0026201610
-
Assembly and intracellular transport of major histocompatibility complex molecules
-
J.J. Neefjes T.N. Schumacher H.L. Ploegh Assembly and intracellular transport of major histocompatibility complex molecules Curr. Opin. Cell Biol. 3 1991 601-609
-
(1991)
Curr. Opin. Cell Biol.
, vol.3
, pp. 601-609
-
-
Neefjes, J.J.1
Schumacher, T.N.2
Ploegh, H.L.3
-
109
-
-
0021175671
-
A synaptic basis for T-lymphocyte activation
-
M.A. Norcross A synaptic basis for T-lymphocyte activation Ann. Immunol. (Paris) 135D 1984 113-134
-
(1984)
Ann. Immunol. (Paris)
, vol.135 D
, pp. 113-134
-
-
Norcross, M.A.1
-
110
-
-
0028151819
-
Negative selection of lymphocytes
-
G.J. Nossal Negative selection of lymphocytes Cell 76 1994 229-239
-
(1994)
Cell
, vol.76
, pp. 229-239
-
-
Nossal, G.J.1
-
111
-
-
0038725685
-
Negative selection-clearing out the bad apples from the T-cell repertoire
-
E. Palmer Negative selection-clearing out the bad apples from the T-cell repertoire Nat. Rev. Immunol. 3 2003 383-391
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 383-391
-
-
Palmer, E.1
-
112
-
-
1542357608
-
Natural killer lymphocytes: Biology, development, and function
-
M. Papamichail S.A. Perez A.D. Gritzapis C.N. Baxevanis Natural killer lymphocytes: Biology, development, and function Cancer Immunol. Immunother. 53 2004 176-186
-
(2004)
Cancer Immunol. Immunother.
, vol.53
, pp. 176-186
-
-
Papamichail, M.1
Perez, S.A.2
Gritzapis, A.D.3
Baxevanis, C.N.4
-
113
-
-
0023613961
-
Regulation of B-lymphocyte activation, proliferation, and differentiation
-
W.E. Paul M. Brown P. Hornbeck J. Mizuguchi J. Ohara E. Rabin C. Snapper W. Tsang Regulation of B-lymphocyte activation, proliferation, and differentiation Ann. NY Acad. Sci. 505 1987 82-89
-
(1987)
Ann. NY Acad. Sci.
, vol.505
, pp. 82-89
-
-
Paul, W.E.1
Brown, M.2
Hornbeck, P.3
Mizuguchi, J.4
Ohara, J.5
Rabin, E.6
Snapper, C.7
Tsang, W.8
-
114
-
-
0141447817
-
T-cell receptor signal transmission: Who gives an ITAM?
-
L.A. Pitcher N.S. van Oers T-cell receptor signal transmission: Who gives an ITAM? Trends Immunol. 24 2003 554-560
-
(2003)
Trends Immunol.
, vol.24
, pp. 554-560
-
-
Pitcher, L.A.1
van Oers, N.S.2
-
115
-
-
0030943398
-
T cell antigen receptor signal transduction
-
D. Qian A. Weiss T cell antigen receptor signal transduction Curr. Opin. Cell Biol. 9 1997 205-212
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 205-212
-
-
Qian, D.1
Weiss, A.2
-
116
-
-
0030046923
-
Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling
-
D. Qian M.N. Mollenauer A. Weiss Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling J. Exp. Med. 183 1996 611-620
-
(1996)
J. Exp. Med.
, vol.183
, pp. 611-620
-
-
Qian, D.1
Mollenauer, M.N.2
Weiss, A.3
-
118
-
-
0036898764
-
A temporal and spatial summation model for T-cell activation: Signal integration and antigen decoding
-
J. Rachmilewitz A. Lanzavecchia A temporal and spatial summation model for T-cell activation: Signal integration and antigen decoding Trends Immunol. 23 2002 592-595
-
(2002)
Trends Immunol.
, vol.23
, pp. 592-595
-
-
Rachmilewitz, J.1
Lanzavecchia, A.2
-
120
-
-
0028201339
-
Selective events in T cell development
-
E. Robey B.J. Fowlkes Selective events in T cell development Annu. Rev. Immunol. 12 1994 675-705
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 675-705
-
-
Robey, E.1
Fowlkes, B.J.2
-
121
-
-
0032971227
-
Degradation of cell proteins and the generation of MHC class I-presented peptides
-
K.L. Rock A.L. Goldberg Degradation of cell proteins and the generation of MHC class I-presented peptides Annu. Rev. Immunol. 17 1999 739-779
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 739-779
-
-
Rock, K.L.1
Goldberg, A.L.2
-
122
-
-
0028335703
-
Peptide-induced conformational changes in class I molecules. Direct detection by flow cytometry
-
E.M. Rohren D.J. McCormick L.R. Pease Peptide-induced conformational changes in class I molecules. Direct detection by flow cytometry J. Immunol. 152 1994 5337-5343
-
(1994)
J. Immunol.
, vol.152
, pp. 5337-5343
-
-
Rohren, E.M.1
McCormick, D.J.2
Pease, L.R.3
-
123
-
-
0034903068
-
The impact of duration versus extent of TCR occupancy on T cell activation: A revision of the kinetic proofreading model
-
C. Rosette G. Werlen M.A. Daniels P.O. Holman S.M. Alam P.J. Travers N.R. Gascoigne E. Palmer S.C. Jameson The impact of duration versus extent of TCR occupancy on T cell activation: A revision of the kinetic proofreading model Immunity 15 2001 59-70
-
(2001)
Immunity
, vol.15
, pp. 59-70
-
-
Rosette, C.1
Werlen, G.2
Daniels, M.A.3
Holman, P.O.4
Alam, S.M.5
Travers, P.J.6
Gascoigne, N.R.7
Palmer, E.8
Jameson, S.C.9
-
124
-
-
17944367867
-
Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/ peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life
-
V. Rubio-Godoy V. Dutoit D. Rimoldi D. Lienard F. Lejeune D. Speiser P. Guillaume J.C. Cerottini P. Romero D. Valmori Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life Proc. Natl. Acad. Sci. USA 98 2001 10302-10307
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10302-10307
-
-
Rubio-Godoy, V.1
Dutoit, V.2
Rimoldi, D.3
Lienard, D.4
Lejeune, F.5
Speiser, D.6
Guillaume, P.7
Cerottini, J.C.8
Romero, P.9
Valmori, D.10
-
125
-
-
0035070196
-
The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity
-
M.G. Rudolph J.A. Speir A. Brunmark N. Mattsson M.R. Jackson P.A. Peterson L. Teyton I.A. Wilson The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity Immunity 14 2001 231-242
-
(2001)
Immunity
, vol.14
, pp. 231-242
-
-
Rudolph, M.G.1
Speir, J.A.2
Brunmark, A.3
Mattsson, N.4
Jackson, M.R.5
Peterson, P.A.6
Teyton, L.7
Wilson, I.A.8
-
127
-
-
0036221481
-
Signal transduction mediated by the T cell antigen receptor: The role of adapter proteins
-
L.E. Samelson Signal transduction mediated by the T cell antigen receptor: The role of adapter proteins Annu. Rev. Immunol. 20 2002 371-394
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 371-394
-
-
Samelson, L.E.1
-
128
-
-
0035070797
-
A kinetic window constricts the T cell receptor repertoire in the thymus
-
P.A. Savage M.M. Davis A kinetic window constricts the T cell receptor repertoire in the thymus Immunity 14 2001 243-252
-
(2001)
Immunity
, vol.14
, pp. 243-252
-
-
Savage, P.A.1
Davis, M.M.2
-
129
-
-
0033118739
-
A kinetic basis for T cell receptor repertoire selection during an immune response
-
P.A. Savage J.J. Boniface M.M. Davis A kinetic basis for T cell receptor repertoire selection during an immune response Immunity 10 1999 485-492
-
(1999)
Immunity
, vol.10
, pp. 485-492
-
-
Savage, P.A.1
Boniface, J.J.2
Davis, M.M.3
-
131
-
-
0022242651
-
Autoaggressive T lymphocyte lines recognizing the encephalitogenic region of myelin basic protein: In vitro selection from unprimed rat T lymphocyte populations
-
H.J. Schluesener H. Wekerle Autoaggressive T lymphocyte lines recognizing the encephalitogenic region of myelin basic protein: In vitro selection from unprimed rat T lymphocyte populations J. Immunol. 135 1985 3128-3133
-
(1985)
J. Immunol.
, vol.135
, pp. 3128-3133
-
-
Schluesener, H.J.1
Wekerle, H.2
-
133
-
-
0033696977
-
Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex
-
J.E. Slansky F.M. Rattis L.F. Boyd T. Fahmy E.M. Jaffee J.P. Schneck D.H. Margulies D.M. Pardoll Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex Immunity 13 2000 529-538
-
(2000)
Immunity
, vol.13
, pp. 529-538
-
-
Slansky, J.E.1
Rattis, F.M.2
Boyd, L.F.3
Fahmy, T.4
Jaffee, E.M.5
Schneck, J.P.6
Margulies, D.H.7
Pardoll, D.M.8
-
134
-
-
0034889233
-
Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR
-
M.K. Slifka J.L. Whitton Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR Nat. Immunol. 2 2001 711-717
-
(2001)
Nat. Immunol.
, vol.2
, pp. 711-717
-
-
Slifka, M.K.1
Whitton, J.L.2
-
136
-
-
0037036114
-
Dynamic imaging of T cell-dendritic cell interactions in lymph nodes
-
S. Stoll J. Delon T.M. Brotz R.N. Germain Dynamic imaging of T cell-dendritic cell interactions in lymph nodes Science 296 2002 1873-1876
-
(2002)
Science
, vol.296
, pp. 1873-1876
-
-
Stoll, S.1
Delon, J.2
Brotz, T.M.3
Germain, R.N.4
-
137
-
-
0032191837
-
Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes
-
T. Sugawara T. Moriguchi E. Nishida Y. Takahama Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes Immunity 9 1998 565-574
-
(1998)
Immunity
, vol.9
, pp. 565-574
-
-
Sugawara, T.1
Moriguchi, T.2
Nishida, E.3
Takahama, Y.4
-
138
-
-
0030176270
-
Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response
-
Y. Sykulev M. Joo I. Vturina T.J. Tsomides H.N. Eisen Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response Immunity 4 1996 565-571
-
(1996)
Immunity
, vol.4
, pp. 565-571
-
-
Sykulev, Y.1
Joo, M.2
Vturina, I.3
Tsomides, T.J.4
Eisen, H.N.5
-
140
-
-
0025066253
-
Sequence and diversity of bovine T-cell receptor beta-chain genes
-
A. Tanaka N. Ishiguro M. Shinagawa Sequence and diversity of bovine T-cell receptor beta-chain genes Immunogenetics 32 1990 263-271
-
(1990)
Immunogenetics
, vol.32
, pp. 263-271
-
-
Tanaka, A.1
Ishiguro, N.2
Shinagawa, M.3
-
141
-
-
0024550342
-
Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C
-
R. Testi J.H. Phillips L.L. Lanier Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C J. Immunol. 142 1989 1854-1860
-
(1989)
J. Immunol.
, vol.142
, pp. 1854-1860
-
-
Testi, R.1
Phillips, J.H.2
Lanier, L.L.3
-
143
-
-
0026710559
-
Diversity of T-cell receptor alpha gene transcripts in the newborn and adult periphery
-
S.D. Thompson M. Larche A.R. Manzo J.L. Hurwitz Diversity of T-cell receptor alpha gene transcripts in the newborn and adult periphery Immunogenetics 36 1992 95-103
-
(1992)
Immunogenetics
, vol.36
, pp. 95-103
-
-
Thompson, S.D.1
Larche, M.2
Manzo, A.R.3
Hurwitz, J.L.4
-
144
-
-
0022457767
-
Structure and diversity of the human T-cell receptor beta-chain variable region genes
-
J.P. Tillinghast M.A. Behlke D.Y. Loh Structure and diversity of the human T-cell receptor beta-chain variable region genes Science 233 1986 879-883
-
(1986)
Science
, vol.233
, pp. 879-883
-
-
Tillinghast, J.P.1
Behlke, M.A.2
Loh, D.Y.3
-
145
-
-
4644333888
-
Salmonella escape from antigen presentation can be overcome by targeting bacteria to Fc gamma receptors on dendritic cells
-
J.A. Tobar P.A. Gonzalez A.M. Kalergis Salmonella escape from antigen presentation can be overcome by targeting bacteria to Fc gamma receptors on dendritic cells J. Immunol. 173 2004 4058-4065
-
(2004)
J. Immunol.
, vol.173
, pp. 4058-4065
-
-
Tobar, J.A.1
Gonzalez, P.A.2
Kalergis, A.M.3
-
146
-
-
6344272217
-
Functionally impaired HIV-specific CD8 T cells show high affinity TCR-ligand interactions
-
T. Ueno H. Tomiyama M. Fujiwara S. Oka M. Takiguchi Functionally impaired HIV-specific CD8 T cells show high affinity TCR-ligand interactions J. Immunol. 173 2004 5451-5457
-
(2004)
J. Immunol.
, vol.173
, pp. 5451-5457
-
-
Ueno, T.1
Tomiyama, H.2
Fujiwara, M.3
Oka, S.4
Takiguchi, M.5
-
147
-
-
0031172162
-
Serial triggering of TCRs: A basis for the sensitivity and specificity of antigen recognition
-
S. Valitutti A. Lanzavecchia Serial triggering of TCRs: A basis for the sensitivity and specificity of antigen recognition Immunol. Today 18 1997 299-304
-
(1997)
Immunol. Today
, vol.18
, pp. 299-304
-
-
Valitutti, S.1
Lanzavecchia, A.2
-
148
-
-
0028961573
-
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
-
S. Valitutti M. Dessing K. Aktories H. Gallati A. Lanzavecchia Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton J. Exp. Med. 181 1995 577-584
-
(1995)
J. Exp. Med.
, vol.181
, pp. 577-584
-
-
Valitutti, S.1
Dessing, M.2
Aktories, K.3
Gallati, H.4
Lanzavecchia, A.5
-
150
-
-
0034948337
-
The TCR triggering puzzle
-
P.A. van der Merwe The TCR triggering puzzle Immunity 14 2001 665-668
-
(2001)
Immunity
, vol.14
, pp. 665-668
-
-
van der Merwe, P.A.1
-
151
-
-
0036604984
-
Formation and function of the immunological synapse
-
P.A. van der Merwe Formation and function of the immunological synapse Curr. Opin. Immunol. 14 2002 293-298
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 293-298
-
-
van der Merwe, P.A.1
-
152
-
-
0042971650
-
Molecular interactions mediating T cell antigen recognition
-
P.A. van der Merwe S.J. Davis Molecular interactions mediating T cell antigen recognition Annu. Rev. Immunol. 21 2003 659-684
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 659-684
-
-
van der Merwe, P.A.1
Davis, S.J.2
-
153
-
-
0034005120
-
Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition
-
P.A. van der Merwe S.J. Davis A.S. Shaw M.L. Dustin Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition Sem. Immunol. 12 2000 5-21
-
(2000)
Sem. Immunol.
, vol.12
, pp. 5-21
-
-
van der Merwe, P.A.1
Davis, S.J.2
Shaw, A.S.3
Dustin, M.L.4
-
154
-
-
0035979265
-
Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide
-
C. Viret X. He C.A. Janeway Jr. Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide Proc. Natl. Acad. Sci. USA 98 2001 9243-9248
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9243-9248
-
-
Viret, C.1
He, X.2
Janeway Jr., C.A.3
-
155
-
-
0028032155
-
Positive selection of lymphocytes
-
H. von Boehmer Positive selection of lymphocytes Cell 76 1994 219-228
-
(1994)
Cell
, vol.76
, pp. 219-228
-
-
von Boehmer, H.1
-
156
-
-
0030963615
-
Structure and function of the pre-T cell receptor
-
H. von Boehmer H.J. Fehling Structure and function of the pre-T cell receptor Annu. Rev. Immunol. 15 1997 433-452
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 433-452
-
-
von Boehmer, H.1
Fehling, H.J.2
-
157
-
-
0026752591
-
A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor
-
R.L. Wange A.N. Kong L.E. Samelson A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor J. Biol. Chem. 267 1992 11685-11688
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11685-11688
-
-
Wange, R.L.1
Kong, A.N.2
Samelson, L.E.3
-
158
-
-
0028014460
-
Signal transduction by lymphocyte antigen receptors
-
A. Weiss D.R. Littman Signal transduction by lymphocyte antigen receptors Cell 76 1994 263-274
-
(1994)
Cell
, vol.76
, pp. 263-274
-
-
Weiss, A.1
Littman, D.R.2
-
159
-
-
0023156442
-
Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene
-
A. Weiss R. Shields M. Newton B. Manger J. Imboden Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene J. Immunol. 138 1987 2169-2176
-
(1987)
J. Immunol.
, vol.138
, pp. 2169-2176
-
-
Weiss, A.1
Shields, R.2
Newton, M.3
Manger, B.4
Imboden, J.5
-
160
-
-
0023685068
-
Tyrosine phosphorylation of the human T cell antigen receptor zeta-chain: Activation via CD3 but not CD2
-
A.M. Weissman P. Ross E.T. Luong P. Garcia-Morales M.L. Jelachich W.E. Biddison R.D. Klausner L.E. Samelson Tyrosine phosphorylation of the human T cell antigen receptor zeta-chain: Activation via CD3 but not CD2 J. Immunol. 141 1988 3532-3536
-
(1988)
J. Immunol.
, vol.141
, pp. 3532-3536
-
-
Weissman, A.M.1
Ross, P.2
Luong, E.T.3
Garcia-Morales, P.4
Jelachich, M.L.5
Biddison, W.E.6
Klausner, R.D.7
Samelson, L.E.8
-
161
-
-
0037459321
-
Signaling life and death in the thymus: Timing is everything
-
G. Werlen B. Hausmann D. Naeher E. Palmer Signaling life and death in the thymus: Timing is everything Science 299 2003 1859-1863
-
(2003)
Science
, vol.299
, pp. 1859-1863
-
-
Werlen, G.1
Hausmann, B.2
Naeher, D.3
Palmer, E.4
-
163
-
-
23044469067
-
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface
-
L. Wooldridge H.A. van den Berg M. Glick E. Gostick B. Laugel S.L. Hutchinson A. Milicic J.M. Brenchley D.C. Douek D.A. Price A.K. Sewell Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface J. Biol. Chem. 280 2005 27491-27501
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 27491-27501
-
-
Wooldridge, L.1
van den Berg, H.A.2
Glick, M.3
Gostick, E.4
Laugel, B.5
Hutchinson, S.L.6
Milicic, A.7
Brenchley, J.M.8
Douek, D.C.9
Price, D.A.10
Sewell, A.K.11
-
165
-
-
0036224370
-
Inhibition of T cell receptor-coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse
-
T. Zal M.A. Zal N.R. Gascoigne Inhibition of T cell receptor-coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse Immunity 16 2002 521-534
-
(2002)
Immunity
, vol.16
, pp. 521-534
-
-
Zal, T.1
Zal, M.A.2
Gascoigne, N.R.3
-
166
-
-
0036568944
-
Cutting edge: TCR engagement and triggering in the absence of large-scale molecular segregation at the T cell-APC contact site
-
R. Zaru T.O. Cameron L.J. Stern S. Muller S. Valitutti Cutting edge: TCR engagement and triggering in the absence of large-scale molecular segregation at the T cell-APC contact site J. Immunol. 168 2002 4287-4291
-
(2002)
J. Immunol.
, vol.168
, pp. 4287-4291
-
-
Zaru, R.1
Cameron, T.O.2
Stern, L.J.3
Muller, S.4
Valitutti, S.5
-
167
-
-
0032992072
-
Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line
-
W. Zhang B.J. Irvin R.P. Trible R.T. Abraham L.E. Samelson Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line Int. Immunol. 11 1999 943-950
-
(1999)
Int. Immunol.
, vol.11
, pp. 943-950
-
-
Zhang, W.1
Irvin, B.J.2
Trible, R.P.3
Abraham, R.T.4
Samelson, L.E.5
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