LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo

Journal of Immunology

Volumn 173, Issue 7, 2004, Pages 4443-4451

  Kandula, Sravanthi ^a   Abraham, Clara ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD18 ANTIGEN; CD4 ANTIGEN; IMMUNOGLOBULIN G2A; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; OVALBUMIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; CANCER CELL CULTURE; FIBROSARCOMA; IMMUNIZATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 4644312322     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.7.4443     Document Type: Article

References (51)

1. Kurzinger, K., T. Reynolds, R. N. Germain, D. Davignon, E. Martz, and T. A. Springer. 1981. A novel lymphocyte function-associated antigen (LFA-1): cellular distribution, quantitative expression, and structure. J. Immunol. 127:596.
2. Springer, T. A. 1990. Adhesion receptors of the immune system. Nature 346:425.
3. Lub, M., Y. van Kooyk, and C. G. Figdor. 1995. Ins and outs of LFA-1. Immunol. Today 16:479.
4. Larson, R. S., and T. A. Springer. 1990. Structure and function of leukocyte integrins. Immunol. Rev. 114:180.
5. 2 integrins and selectin ligands. Curr. Opin. Hematol. 9:30.
6. Moriyama, H., K. Yokono, K. Amano, M. Nagata, Y. Hasegawa, N. Okamoto, K. Tsukamoto, M. Miki, R. Yoneda, N. Yagi, et al. 1996. Induction of tolerance in murine autoimmune diabetes by transient blockade of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 pathway. J. Immunol. 157:3737.
7. Kato, Y., A. Yamataka, H. Yagita, H. Bashuda, K. Okumura, and T. Miyano. 1995. Prevention of fetal bowel allograft rejection by combined treatment with anti-ICAM-1 and anti-LFA-1 antibodies. J. Pediat. Surg. 30:1093.
8. Yacyshyn, B. R., M. B. Bowen-Yacyshyn, L. Jewell, J. A. Tami, C. F. Bennett, D. L. Kisner, and W. R. Shanahan, Jr. 1998. A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease. Gastroenterology 114:1133.
9. Dustin, M. L., and T. A. Springer. 1989. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341:619.
10. Kuhlman, P., V. T. Moy, B. A. Lollo, and A. A. Brian. 1991. The accessor function of murine intercellular adhesion molecule-1 in T lymphocyte activation: contributions of adhesion and co-activation. J. Immunol. 146:1773.
11. Ybarrondo, B., A. M. O'Rourke, A. A. Brian, and M. F. Mescher. 1994. Contribution of lymphocyte function associated-1/intercellular adhesion molecule-1 binding to the adhesion/signaling cascade of cytotoxic T lymphocyte activation. J. Exp. Med. 179:359.
12. Bachmann, M. F., K. McKall-Faienza, R. Schmits, D. Bouchard, J. Beach, D. E. Speiser, T. W. Mak, and P. S. Ohashi. 1997. Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation. Immunity 7:549.
13. + T cell responses to isolated antigenic class II proteins by fibronectin and intercellular adhesion molecule-1. J. Immunol. 159:1676.
14. Abraham, C., J. Griffith, and J. Miller. 1999. The dependence for leukocyte function-associated antigen-1/ICAM-1 interactions in T cell activation cannot be overcome by expression of high density TCR ligand. J. Immunol. 162:4399.
15. Abraham, C., and J. Miller. 2001. Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1. J. Immunol 167:5193.
16. Van Seventer, G. A., Y. Shimizu, K. J. Horgan, and S. Shaw. 1990. The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells. J. Immunol. 144:4579.
17. Van Seventer, G. A., W. Newman, Y. Shimizu, T. B. Nutman, Y. Tanaka, K. J. Horgan, T. V. Gopal, E. Ennis, D. O'Sullivan, H. Grey, and S. Shaw. 1991. Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1. J. Exp. Med. 174:901.
18. Zuckerman, L. A., L. Pullen, and J. Miller. 1998. Functional consequences of costimulation by ICAM-1 on IL-2 gene expression and T cell activation. J. Immunol. 160:3259.
19. + T cells: ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response. J. Immunol. 155:45.
20. + T cells. J. Exp. Med 185:641.
21. Scharffetter-Kochanek, K., K. Norman, D. C. Bullard, I. Lorenzo, N. P. van Nood, S. Rich, W. Smith, and A. L. Beaudet. 1996. Generation and characterization of a CD18 complete knock-out mouse: new insights in the function of the CD18 molecule? J. Invest. Dermatol. 106:809.
22. Scharffetter-Kochanek, K., H. Lu, K. Norman, N. van Nood, F. Munoz, S. Grabbe, M. McArthur, I. Lorenzo, S. Kaplan, K. Ley, et al. 1998. Spontaneous skin ulceration and defective T cell function in CD18 null mice. J. Exp. Med. 188:119.
23. 2 integrin leukocyte function-associated antigen-1. J. Immunol. 157:5375.
24. Randolph, G., and M. Furie. 1996. Mononuclear phagocytes egress from an in vitro model of the vascular wall by migrating across endothelium in the basal to apical direction: role of intercellular adhesion molecule 1 and the CD11/CD18 integrins. J. Exp. Med. 183:451.
25. Warnock, R., S. Askari, E. Butcher, and U. von Andrian. 1998. Molecular mechanisms of lymphocyte homing to peripheral lymph nodes. J. Exp. Med. 187:205.
26. Berlin-Rufenach, C., F. Otto, M. Mathies, J. Westermann, M. J. Owen, A. Hamann, and N. Hogg. 1999. Lymphocytes migration in lymphocyte function-associated antigen (LFA)-1-deficient mice. J. Exp. Med. 189:1467.
27. Schmits, R., T. M. Kundig, D. M. Baker, G. Shumaker, J. J. Simard, G. Duncan, A. Wakeham, A. Shahinian, A. van der Heiden, M. F. Bachmann, et al. 1996. LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. J. Exp. Med. 183:1415.
28. Schonlau, F., K. Scharffetter-Kochanek, S. Grabbe, B. Pietz, C. Sorg, and C. Sunderkotter. 2000. In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response. Eur. J. Immunol. 30:2729.
29. Prince, J. E., C. F. Brayton, M. C. Fossett, J. A. Durand, S. L. Kaplan, C. W. Smith, and C. M. Ballantyne. 2001. The differential roles of LFA-1 and Mac-1 in host defense against systemic infection with Streptococcus pneumoniae. J. Immunol. 166:7362.
30. Andrew, D. P., J. P. Spellberg, H. Takimoto, R. Schmits, T. W. Mak, and M. M. Zukowski. 1998. Transendothelial migration and trafficking of leukocytes in LFA-1-deficient mice. Eur. J. Immunol. 28:1959.
31. 2 integrins are required for skin homing of primed T cells but not for priming naive T cells. J. Clin. Invest. 109:183.
32. Zuckerman, L. A., A. J. Sant, and J. Miller. 1995. Identification of a unique costimulatory activity for murine T helper 1 T cell clones. J. Immunol. 154:4503.
33. Salomon, B., and J. A. Bluestone. 1998. Cutting edge: LFA-1 interaction with ICAM-1 and ICAM-2 regulates Th2 cytokine production. J. Immunol. 161:5138.
34. Jenks, S. A., and J. Miller. 1999. Inhibition of IL-4 responses after T cell priming in the context of LFA-1 costimulation is not reversed by restimulation in the presence of CD28 costimulation. J. Immunol. 164:72.
35. Camacho, S. A., W. R. Heath, F. R. Carbone, N. Sarvetnick, A. LeBon, L. Karlsson, P. A. Peterson, and S. R. Webb. 2001. A key role for ICAM-1 in generating effector cells mediating inflammatory responses. Nat. Immunol. 2:523.
36. Smits, H. H., E. C. de Jong, J. H. N. Schuitemaker, T. B. H. Geijtenbeek, Y. van Kooyk, M. L. Kapsenberg, and E. A. Wierenga. 2002. Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development. J. Immunol. 168:1710.
37. Bird, J. J., D. R. Brown, A. C. Mullen, N. H. Moskowitz, M. A. Mahowald, J. R. Sider, T. F. Gajewski, C.-R. Wang, and S. L. Reiner. 1998. Helper T cell differentiation is controlled by the cell cycle. Immunity 9:229.
38. Reinhardt, R. L., D. C. Bullard, C. T. Weaver, and M. K. Jenkins. 2003. Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation. J. Exp. Med. 197:751.
39. + T cells. J. Immunol. 159:591.
40. Rogers, P. R., and M. Croft. 2000. CD28, Ox-40, LFA-1, and CD4 modulation of Th1/Th2 differentiation is directly dependent on the dose of antigen. J. Immunol. 164:2955.
41. Straw, A. D., A. S. MacDonald, E. Y. Denkers, and E. J. Pearce. 2003. CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses. J. Immunol. 170:727.
42. Wang, L., J. J. Y. Chen, B. B. Gelman, R. Konig, and M. W. Cloyd. 1999. A novel mechanism of CD4 lymphocyte depletion involves effects of HIV on resting lymphocytes: induction of lymph node homing and apoptosis upon secondary signaling through homing receptors. J. Immunol. 162:268.
43. 2-integrin) molecules. Tissue Antigens 48:127.
44. Winter, S. S., J. J. Sweatman, M. B. Lawrence, T. H. Rhoades, A. L. Hart, and R. S. Larson. 2001. Enhanced T-lineage acute lymphoblastic leukemia cell survival on bone marrow stroma requires involvement of LFA-1 and ICAM-1. Br. J. Hematol. 115:862.
45. Palmer, E. M., L. Farrokh-Siar, J. M. van Seventer, and G. A. van Seventer. 2001. IL-12 decreases activation-induced cell death in human naive Th cells costimulated by intercellular adhesion molecule-1. I. IL-12 alters caspase processing and inhibits enzyme function. J. Immunol. 167:749.
46. Thatte, J., V. Dabak, M. B. Williams, T. J. Braciale, and K. Ley. 2003. LFA-1 is required for retention of effector CD8 T cells in mouse lungs. Blood 101:4916.
47. Matloubian, M., C. G. Lo, G. Cinamon, M. J. Lesneski, Y. Xu, V. Brinkmann, M. L. Allende, R. L. Proia, and J. G. Cyster. 2004. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on SIP receptor 1. Nature 427:355.
48. Monks, C. R. F., B. A. Freiberg, H. Kupfer, N. Sciaky, and A. Kupfer. 1998. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395:82.
49. Grakoui, A., S. K. Bromley, C. Sumen, M. M. Davis, A. S. Shaw, P. M. Allen, and M. L. Dustin. 1999. The immunological synapse: a molecular machine controlling T cell activation. Science 285:221.
50. Lo, C. G., T. T. Lu, and J. G. Cyster. 2003. Integrin-dependence of lymphocyte entry into the splenic white pulp. J. Exp. Med. 197:353.
51. Lu, T. T., and J. G. Cyster. 2002. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 297:409.