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Volumn 6, Issue 1, 2005, Pages 65-72

Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; MISSHAPEN NCK INTERACTING KINASE RELATED KINASE; PROTEIN C JUN; PROTEIN SERINE THREONINE KINASE; STRESS ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 12344298492     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1145     Document Type: Article
Times cited : (52)

References (36)
  • 1
    • 0028859281 scopus 로고
    • Selective requirement for MAP kinase activation in thymocyte differentiation
    • Alberola-Ila, J., Forbush, K.A., Seger, R., Krebs, E.G. & Perlmutter, R.M. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373, 620-623 (1995).
    • (1995) Nature , vol.373 , pp. 620-623
    • Alberola-Ila, J.1    Forbush, K.A.2    Seger, R.3    Krebs, E.G.4    Perlmutter, R.M.5
  • 2
    • 0032493920 scopus 로고    scopus 로고
    • Positive selection through a motif in the αβ T cell receptor
    • Backstrom, B.T., Muller, U., Hausmann, B. & Palmer, E. Positive selection through a motif in the αβ T cell receptor. Science 281, 835-838 (1998).
    • (1998) Science , vol.281 , pp. 835-838
    • Backstrom, B.T.1    Muller, U.2    Hausmann, B.3    Palmer, E.4
  • 3
    • 0034720881 scopus 로고    scopus 로고
    • A motif in the αβ T-cell receptor controls positive selection by modulating Erk activity
    • Werlen, G., Hausmann, B. & Palmer, E. A motif in the αβ T-cell receptor controls positive selection by modulating Erk activity. Nature 406, 422-426 (2000).
    • (2000) Nature , vol.406 , pp. 422-426
    • Werlen, G.1    Hausmann, B.2    Palmer, E.3
  • 4
    • 0034720880 scopus 로고    scopus 로고
    • CD3δ couples T-cell receptor signalling to Erk activation and thymocyte positive selection
    • Delgado, P., Fernandez, E., Dave, V., Kappes, D. & Alarcon, B. CD3δ couples T-cell receptor signalling to Erk activation and thymocyte positive selection. Nature 406, 426-430 (2000).
    • (2000) Nature , vol.406 , pp. 426-430
    • Delgado, P.1    Fernandez, E.2    Dave, V.3    Kappes, D.4    Alarcon, B.5
  • 5
    • 0036063264 scopus 로고    scopus 로고
    • + thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation
    • + thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation. Immunity 16, 839-848 (2002).
    • (2002) Immunity , vol.16 , pp. 839-848
    • Hailman, E.1    Burack, W.R.2    Shaw, A.S.3    Dustin, M.L.4    Allen, P.M.5
  • 6
    • 1642264751 scopus 로고    scopus 로고
    • Calcineurin B1 is essential for positive but not negative selection during thymocyte development
    • Neilson, J.R., Winslow, M.M., Hur, E.M. & Crabtree, G.R. Calcineurin B1 is essential for positive but not negative selection during thymocyte development. Immunity 20, 255-266 (2004).
    • (2004) Immunity , vol.20 , pp. 255-266
    • Neilson, J.R.1    Winslow, M.M.2    Hur, E.M.3    Crabtree, G.R.4
  • 7
    • 0037148840 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
    • Bouillet, P. et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 415 922-926 (2002).
    • (2002) Nature , vol.415 , pp. 922-926
    • Bouillet, P.1
  • 8
    • 0037496129 scopus 로고    scopus 로고
    • The control of apoptosis in lymphocyte selection
    • Strasser, A. & Bouillet, P. The control of apoptosis in lymphocyte selection. Immunol. Rev. 193, 82-92 (2003).
    • (2003) Immunol. Rev. , vol.193 , pp. 82-92
    • Strasser, A.1    Bouillet, P.2
  • 9
    • 0032538817 scopus 로고    scopus 로고
    • + thymocytes
    • + thymocytes. J. Exp. Med. 188, 1817-1830 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 1817-1830
    • Rincon, M.1
  • 10
    • 3042594614 scopus 로고    scopus 로고
    • Detailed analysis of gene expression during development of T cell lineages in the thymus
    • McCarty, N., Shinohara, M.L., Lu, L. & Cantor, H. Detailed analysis of gene expression during development of T cell lineages in the thymus. Proc. Natl. Acad. Sci. USA 101, 9339-9344 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9339-9344
    • McCarty, N.1    Shinohara, M.L.2    Lu, L.3    Cantor, H.4
  • 11
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp, T.R., Bernards, R. & Agami, R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553 (2002).
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 12
    • 0037117550 scopus 로고    scopus 로고
    • A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
    • Sui, G. et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99, 5515-5520 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5515-5520
    • Sui, G.1
  • 13
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • Rubinson, D.A. et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat. Genet. 33, 401-406 (2003).
    • (2003) Nat. Genet. , vol.33 , pp. 401-406
    • Rubinson, D.A.1
  • 14
    • 0034904678 scopus 로고    scopus 로고
    • Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V(beta) domains
    • Baribaud, F. et al. Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V(beta) domains. J. Virol. 75 7453-7461 (2001).
    • (2001) J. Virol. , vol.75 , pp. 7453-7461
    • Baribaud, F.1
  • 16
    • 0037417978 scopus 로고    scopus 로고
    • Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation
    • Zhan, Y. et al. Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation. Proc. Natl. Acad. Sci. USA 100, 1197-1202 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1197-1202
    • Zhan, Y.1
  • 17
    • 0023683669 scopus 로고
    • Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
    • Kisielow, P., Teh, H.S., Bluthmann, H. & von Boehmer, H. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 335, 730-733 (1988).
    • (1988) Nature , vol.335 , pp. 730-733
    • Kisielow, P.1    Teh, H.S.2    Bluthmann, H.3    von Boehmer, H.4
  • 18
    • 0025524074 scopus 로고
    • Early deletion and late positive selection of T cells expressing a male-specific receptor in T-cell receptor transgenic mice
    • Teh, H.S. et al. Early deletion and late positive selection of T cells expressing a male-specific receptor in T-cell receptor transgenic mice. Dev. Immunol. 1, 1-10 (1990).
    • (1990) Dev. Immunol. , vol.1 , pp. 1-10
    • Teh, H.S.1
  • 19
    • 0000827468 scopus 로고    scopus 로고
    • Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development
    • Dan, I. et al. Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development. FEBS Lett. 469, 19-23 (2000).
    • (2000) FEBS Lett. , vol.469 , pp. 19-23
    • Dan, I.1
  • 20
    • 0032213509 scopus 로고    scopus 로고
    • The Nck SH2/SH3 adaptor protein: A regulator of multiple intracellular signal transduction events
    • McCarty, J.H. The Nck SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events. Bioessays 20 913-921 (1998).
    • (1998) Bioessays , vol.20 , pp. 913-921
    • McCarty, J.H.1
  • 21
    • 0037188899 scopus 로고    scopus 로고
    • Recruitment of Nck by CD3E reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation
    • Gil, D., Schamel, W.W., Montoya, M., Sanchez-Madrid, F. & Alarcon, B. Recruitment of Nck by CD3E reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Cell 109, 901-912 (2002).
    • (2002) Cell , vol.109 , pp. 901-912
    • Gil, D.1    Schamel, W.W.2    Montoya, M.3    Sanchez-Madrid, F.4    Alarcon, B.5
  • 22
    • 0037047353 scopus 로고    scopus 로고
    • A new trigger for T cells
    • Davis, M.M. A new trigger for T cells. Cell 110, 285-287 (2002).
    • (2002) Cell , vol.110 , pp. 285-287
    • Davis, M.M.1
  • 23
    • 0034190231 scopus 로고    scopus 로고
    • The Jnk and P38 MAP kinase signaling pathways in T cell-mediated immune responses
    • Rincon, M., Flavell, R.A. & Davis, R.A. The Jnk and P38 MAP kinase signaling pathways in T cell-mediated immune responses. Free Radic. Biol. Med. 28, 1328-1337 (2000).
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1328-1337
    • Rincon, M.1    Flavell, R.A.2    Davis, R.A.3
  • 24
    • 0033545386 scopus 로고    scopus 로고
    • Jnk2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development
    • Sabapathy, K. et al. Jnk2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. Curr. Biol. 9, 116-125 (1999).
    • (1999) Curr. Biol. , vol.9 , pp. 116-125
    • Sabapathy, K.1
  • 25
    • 0035808769 scopus 로고    scopus 로고
    • 2-terminal kinase (Jnk)1 and Jnk2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation
    • 2-terminal kinase (Jnk)1 and Jnk2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation. J. Exp. Med. 193, 317-328 (2001).
    • (2001) J. Exp. Med. , vol.193 , pp. 317-328
    • Sabapathy, K.1
  • 26
    • 0035851204 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family members are coordinately regulated by the Jnk pathway and require Bax to induce apoptosis in neurons
    • Harris, C.A. & Johnson, E.M., Jr. BH3-only Bcl-2 family members are coordinately regulated by the Jnk pathway and require Bax to induce apoptosis in neurons. J. Biol. Chem. 276, 37754-37760 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 37754-37760
    • Harris, C.A.1    Johnson Jr., E.M.2
  • 27
    • 0035053624 scopus 로고    scopus 로고
    • Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
    • Putcha, G.V. et al. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron 29, 615-628 (2001).
    • (2001) Neuron. , vol.29 , pp. 615-628
    • Putcha, G.V.1
  • 28
    • 0035049449 scopus 로고    scopus 로고
    • Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
    • Whitfield, J., Neame, S.J., Paquet, L., Bernard, O. & Ham, J. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29, 629-643 (2001).
    • (2001) Neuron. , vol.29 , pp. 629-643
    • Whitfield, J.1    Neame, S.J.2    Paquet, L.3    Bernard, O.4    Ham, J.5
  • 29
    • 0035341895 scopus 로고    scopus 로고
    • The Ste20 group kinases as regulators of MAP kinase cascades
    • Dan, I., Watanabe, N.M. & Kusumi, A. The Ste20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol. 11, 220-230 (2001).
    • (2001) Trends Cell Biol. , vol.11 , pp. 220-230
    • Dan, I.1    Watanabe, N.M.2    Kusumi, A.3
  • 30
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the Jnk group of MAP kinases
    • Davis, R.J. Signal transduction by the Jnk group of MAP kinases. Cell 103, 239-252 (2000).
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 31
    • 0031044561 scopus 로고    scopus 로고
    • MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: Upstream regulators of the c-Jun amino-terminal kinases?
    • Fanger, G.R., Gerwins, P., Widmann, C., Jarpe, M.B. & Johnson, G.L. MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases? Curr. Opin. Genet. Dev. 7, 67-74 (1997).
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 67-74
    • Fanger, G.R.1    Gerwins, P.2    Widmann, C.3    Jarpe, M.B.4    Johnson, G.L.5
  • 32
    • 0036269755 scopus 로고    scopus 로고
    • 2-terminal kinase
    • 2-terminal kinase. Mol. Cell. Biol. 22, 4929-4942 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4929-4942
    • Lei, K.1
  • 33
    • 0035852707 scopus 로고    scopus 로고
    • Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)
    • Behrens, A. et al. Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT). Proc. Natl. Acad. Sci. USA 98, 1769-1774 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1769-1774
    • Behrens, A.1
  • 34
    • 0036533386 scopus 로고    scopus 로고
    • New perspectives on a developmental dilemma: The kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision
    • Singer, A. New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision. Curr. Opin. Immunol. 14, 207-215 (2002).
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 207-215
    • Singer, A.1
  • 35
    • 0032478068 scopus 로고    scopus 로고
    • Two distinct pathways of positive selection for thymocytes
    • Akashi, K., Kondo, M. & Weissman, I.L. Two distinct pathways of positive selection for thymocytes. Proc. Natl. Acad. Sci. USA 95, 2486-2491 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2486-2491
    • Akashi, K.1    Kondo, M.2    Weissman, I.L.3
  • 36
    • 0033580466 scopus 로고    scopus 로고
    • The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway
    • Ninomiya-Tsuji, J. et al. The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398, 252-256 (1999).
    • (1999) Nature , vol.398 , pp. 252-256
    • Ninomiya-Tsuji, J.1


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