-
1
-
-
0028859281
-
Selective requirement for MAP kinase activation in thymocyte differentiation
-
Alberola-Ila, J., Forbush, K.A., Seger, R., Krebs, E.G. & Perlmutter, R.M. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373, 620-623 (1995).
-
(1995)
Nature
, vol.373
, pp. 620-623
-
-
Alberola-Ila, J.1
Forbush, K.A.2
Seger, R.3
Krebs, E.G.4
Perlmutter, R.M.5
-
2
-
-
0032493920
-
Positive selection through a motif in the αβ T cell receptor
-
Backstrom, B.T., Muller, U., Hausmann, B. & Palmer, E. Positive selection through a motif in the αβ T cell receptor. Science 281, 835-838 (1998).
-
(1998)
Science
, vol.281
, pp. 835-838
-
-
Backstrom, B.T.1
Muller, U.2
Hausmann, B.3
Palmer, E.4
-
3
-
-
0034720881
-
A motif in the αβ T-cell receptor controls positive selection by modulating Erk activity
-
Werlen, G., Hausmann, B. & Palmer, E. A motif in the αβ T-cell receptor controls positive selection by modulating Erk activity. Nature 406, 422-426 (2000).
-
(2000)
Nature
, vol.406
, pp. 422-426
-
-
Werlen, G.1
Hausmann, B.2
Palmer, E.3
-
4
-
-
0034720880
-
CD3δ couples T-cell receptor signalling to Erk activation and thymocyte positive selection
-
Delgado, P., Fernandez, E., Dave, V., Kappes, D. & Alarcon, B. CD3δ couples T-cell receptor signalling to Erk activation and thymocyte positive selection. Nature 406, 426-430 (2000).
-
(2000)
Nature
, vol.406
, pp. 426-430
-
-
Delgado, P.1
Fernandez, E.2
Dave, V.3
Kappes, D.4
Alarcon, B.5
-
6
-
-
1642264751
-
Calcineurin B1 is essential for positive but not negative selection during thymocyte development
-
Neilson, J.R., Winslow, M.M., Hur, E.M. & Crabtree, G.R. Calcineurin B1 is essential for positive but not negative selection during thymocyte development. Immunity 20, 255-266 (2004).
-
(2004)
Immunity
, vol.20
, pp. 255-266
-
-
Neilson, J.R.1
Winslow, M.M.2
Hur, E.M.3
Crabtree, G.R.4
-
7
-
-
0037148840
-
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
-
Bouillet, P. et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 415 922-926 (2002).
-
(2002)
Nature
, vol.415
, pp. 922-926
-
-
Bouillet, P.1
-
8
-
-
0037496129
-
The control of apoptosis in lymphocyte selection
-
Strasser, A. & Bouillet, P. The control of apoptosis in lymphocyte selection. Immunol. Rev. 193, 82-92 (2003).
-
(2003)
Immunol. Rev.
, vol.193
, pp. 82-92
-
-
Strasser, A.1
Bouillet, P.2
-
9
-
-
0032538817
-
+ thymocytes
-
+ thymocytes. J. Exp. Med. 188, 1817-1830 (1998).
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1817-1830
-
-
Rincon, M.1
-
10
-
-
3042594614
-
Detailed analysis of gene expression during development of T cell lineages in the thymus
-
McCarty, N., Shinohara, M.L., Lu, L. & Cantor, H. Detailed analysis of gene expression during development of T cell lineages in the thymus. Proc. Natl. Acad. Sci. USA 101, 9339-9344 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9339-9344
-
-
McCarty, N.1
Shinohara, M.L.2
Lu, L.3
Cantor, H.4
-
11
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T.R., Bernards, R. & Agami, R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553 (2002).
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
12
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui, G. et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99, 5515-5520 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
-
13
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson, D.A. et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat. Genet. 33, 401-406 (2003).
-
(2003)
Nat. Genet.
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
-
14
-
-
0034904678
-
Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V(beta) domains
-
Baribaud, F. et al. Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V(beta) domains. J. Virol. 75 7453-7461 (2001).
-
(2001)
J. Virol.
, vol.75
, pp. 7453-7461
-
-
Baribaud, F.1
-
16
-
-
0037417978
-
Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation
-
Zhan, Y. et al. Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation. Proc. Natl. Acad. Sci. USA 100, 1197-1202 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1197-1202
-
-
Zhan, Y.1
-
17
-
-
0023683669
-
Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
-
Kisielow, P., Teh, H.S., Bluthmann, H. & von Boehmer, H. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 335, 730-733 (1988).
-
(1988)
Nature
, vol.335
, pp. 730-733
-
-
Kisielow, P.1
Teh, H.S.2
Bluthmann, H.3
von Boehmer, H.4
-
18
-
-
0025524074
-
Early deletion and late positive selection of T cells expressing a male-specific receptor in T-cell receptor transgenic mice
-
Teh, H.S. et al. Early deletion and late positive selection of T cells expressing a male-specific receptor in T-cell receptor transgenic mice. Dev. Immunol. 1, 1-10 (1990).
-
(1990)
Dev. Immunol.
, vol.1
, pp. 1-10
-
-
Teh, H.S.1
-
19
-
-
0000827468
-
Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development
-
Dan, I. et al. Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development. FEBS Lett. 469, 19-23 (2000).
-
(2000)
FEBS Lett.
, vol.469
, pp. 19-23
-
-
Dan, I.1
-
20
-
-
0032213509
-
The Nck SH2/SH3 adaptor protein: A regulator of multiple intracellular signal transduction events
-
McCarty, J.H. The Nck SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events. Bioessays 20 913-921 (1998).
-
(1998)
Bioessays
, vol.20
, pp. 913-921
-
-
McCarty, J.H.1
-
21
-
-
0037188899
-
Recruitment of Nck by CD3E reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation
-
Gil, D., Schamel, W.W., Montoya, M., Sanchez-Madrid, F. & Alarcon, B. Recruitment of Nck by CD3E reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Cell 109, 901-912 (2002).
-
(2002)
Cell
, vol.109
, pp. 901-912
-
-
Gil, D.1
Schamel, W.W.2
Montoya, M.3
Sanchez-Madrid, F.4
Alarcon, B.5
-
22
-
-
0037047353
-
A new trigger for T cells
-
Davis, M.M. A new trigger for T cells. Cell 110, 285-287 (2002).
-
(2002)
Cell
, vol.110
, pp. 285-287
-
-
Davis, M.M.1
-
23
-
-
0034190231
-
The Jnk and P38 MAP kinase signaling pathways in T cell-mediated immune responses
-
Rincon, M., Flavell, R.A. & Davis, R.A. The Jnk and P38 MAP kinase signaling pathways in T cell-mediated immune responses. Free Radic. Biol. Med. 28, 1328-1337 (2000).
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 1328-1337
-
-
Rincon, M.1
Flavell, R.A.2
Davis, R.A.3
-
24
-
-
0033545386
-
Jnk2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development
-
Sabapathy, K. et al. Jnk2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. Curr. Biol. 9, 116-125 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 116-125
-
-
Sabapathy, K.1
-
25
-
-
0035808769
-
2-terminal kinase (Jnk)1 and Jnk2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation
-
2-terminal kinase (Jnk)1 and Jnk2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation. J. Exp. Med. 193, 317-328 (2001).
-
(2001)
J. Exp. Med.
, vol.193
, pp. 317-328
-
-
Sabapathy, K.1
-
26
-
-
0035851204
-
BH3-only Bcl-2 family members are coordinately regulated by the Jnk pathway and require Bax to induce apoptosis in neurons
-
Harris, C.A. & Johnson, E.M., Jr. BH3-only Bcl-2 family members are coordinately regulated by the Jnk pathway and require Bax to induce apoptosis in neurons. J. Biol. Chem. 276, 37754-37760 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37754-37760
-
-
Harris, C.A.1
Johnson Jr., E.M.2
-
27
-
-
0035053624
-
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
-
Putcha, G.V. et al. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron 29, 615-628 (2001).
-
(2001)
Neuron.
, vol.29
, pp. 615-628
-
-
Putcha, G.V.1
-
28
-
-
0035049449
-
Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
-
Whitfield, J., Neame, S.J., Paquet, L., Bernard, O. & Ham, J. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29, 629-643 (2001).
-
(2001)
Neuron.
, vol.29
, pp. 629-643
-
-
Whitfield, J.1
Neame, S.J.2
Paquet, L.3
Bernard, O.4
Ham, J.5
-
29
-
-
0035341895
-
The Ste20 group kinases as regulators of MAP kinase cascades
-
Dan, I., Watanabe, N.M. & Kusumi, A. The Ste20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol. 11, 220-230 (2001).
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 220-230
-
-
Dan, I.1
Watanabe, N.M.2
Kusumi, A.3
-
30
-
-
0034644522
-
Signal transduction by the Jnk group of MAP kinases
-
Davis, R.J. Signal transduction by the Jnk group of MAP kinases. Cell 103, 239-252 (2000).
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
31
-
-
0031044561
-
MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: Upstream regulators of the c-Jun amino-terminal kinases?
-
Fanger, G.R., Gerwins, P., Widmann, C., Jarpe, M.B. & Johnson, G.L. MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases? Curr. Opin. Genet. Dev. 7, 67-74 (1997).
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 67-74
-
-
Fanger, G.R.1
Gerwins, P.2
Widmann, C.3
Jarpe, M.B.4
Johnson, G.L.5
-
32
-
-
0036269755
-
2-terminal kinase
-
2-terminal kinase. Mol. Cell. Biol. 22, 4929-4942 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4929-4942
-
-
Lei, K.1
-
33
-
-
0035852707
-
Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)
-
Behrens, A. et al. Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT). Proc. Natl. Acad. Sci. USA 98, 1769-1774 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1769-1774
-
-
Behrens, A.1
-
34
-
-
0036533386
-
New perspectives on a developmental dilemma: The kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision
-
Singer, A. New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision. Curr. Opin. Immunol. 14, 207-215 (2002).
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 207-215
-
-
Singer, A.1
-
35
-
-
0032478068
-
Two distinct pathways of positive selection for thymocytes
-
Akashi, K., Kondo, M. & Weissman, I.L. Two distinct pathways of positive selection for thymocytes. Proc. Natl. Acad. Sci. USA 95, 2486-2491 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2486-2491
-
-
Akashi, K.1
Kondo, M.2
Weissman, I.L.3
-
36
-
-
0033580466
-
The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-Tsuji, J. et al. The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398, 252-256 (1999).
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
|