-
1
-
-
0042839614
-
Mechanism and regulation of human non-homologous DNA end-joining
-
Lieber, M.R., Y. Ma, U. Pannicke, and K. Schwarz. 2003. Mechanism and regulation of human non-homologous DNA end-joining. Nat. Rev. Mol. Cell Biol. 4:712-720.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 712-720
-
-
Lieber, M.R.1
Ma, Y.2
Pannicke, U.3
Schwarz, K.4
-
2
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 102:553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
3
-
-
0037026482
-
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
-
Di Noia, J., and M.S. Neuberger. 2002. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature. 419:43-48.
-
(2002)
Nature
, vol.419
, pp. 43-48
-
-
Di Noia, J.1
Neuberger, M.S.2
-
4
-
-
0037108463
-
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
-
Rada, C., G.T. Williams, H. Nilsen, D.E. Barnes, T. Lindahl, and M.S. Neuberger. 2002. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 12:1748-1755.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1748-1755
-
-
Rada, C.1
Williams, G.T.2
Nilsen, H.3
Barnes, D.E.4
Lindahl, T.5
Neuberger, M.S.6
-
5
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt, S.K., R.S. Harris, and M.S. Neuberger. 2002. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature. 418:99-103.
-
(2002)
Nature
, vol.418
, pp. 99-103
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
6
-
-
3142765336
-
Class-switch recombination: Interplay of transcription, DNA deamination and DNA repair
-
Chaudhuri, J., and F.W. Alt. 2004. Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat. Rev. Immunol. 4:541-552.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 541-552
-
-
Chaudhuri, J.1
Alt, F.W.2
-
7
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky, K., A. Bar-Shira, S. Gilad, G. Rotman, Y. Ziv, L. Vanagaite, D.A. Tagle, S. Smith, T. Uziel, S. Sfez, et al. 1995. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science. 268:1749-1753.
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
Bar-Shira, A.2
Gilad, S.3
Rotman, G.4
Ziv, Y.5
Vanagaite, L.6
Tagle, D.A.7
Smith, S.8
Uziel, T.9
Sfez, S.10
-
8
-
-
0034605416
-
Ataxia-telangiectasia surveyed in Sweden
-
Lähdesmäki, A., K. Arinbjarnarson, J. Arvidsson, M.E. Segaier, A. Fasth, E. Fernell, D. Gustafsson, V.-A. Oxelius, K. Risberg, J. Yuen, et al. 2000. Ataxia-telangiectasia surveyed in Sweden. [In Swedish.] Lakartidningen. 97:4461-4467.
-
(2000)
Lakartidningen
, vol.97
, pp. 4461-4467
-
-
Lähdesmäki, A.1
Arinbjarnarson, K.2
Arvidsson, J.3
Segaier, M.E.4
Fasth, A.5
Fernell, E.6
Gustafsson, D.7
Oxelius, V.-A.8
Risberg, K.9
Yuen, J.10
-
9
-
-
0036105322
-
Alternative end joining during switch recombination in patients with ataxia-telangiectasia
-
Pan, Q., C. Petit-Frere, A. Lähdesmäki, H. Gregorek, K.H. Chrzanowska, and L. Hammarström. 2002. Alternative end joining during switch recombination in patients with ataxia-telangiectasia. Eur. J. Immunol. 32:1300-1308.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1300-1308
-
-
Pan, Q.1
Petit-Frere, C.2
Lähdesmäki, A.3
Gregorek, H.4
Chrzanowska, K.H.5
Hammarström, L.6
-
10
-
-
8644238314
-
ATM is required for efficient recombination between immunoglobulin switch regions
-
Reina-San-Martin, B., H.T. Chen, A. Nussenzweig, and M.C. Nussenzweig. 2004. ATM is required for efficient recombination between immunoglobulin switch regions. J. Exp. Med. 200:1103-1110.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1103-1110
-
-
Reina-San-Martin, B.1
Chen, H.T.2
Nussenzweig, A.3
Nussenzweig, M.C.4
-
11
-
-
8644242383
-
Immunoglobulin class switch recombination is impaired in Atm-deficient mice
-
Lumsden, J.M., T. McCarty, L.K. Petiniot, R. Shen, C. Barlow, T.A. Wynn, H.C. Morse III, P.J. Gearhart, A. Wynshaw-Boris, E.E. Max, and R.J. Hodes. 2004. Immunoglobulin class switch recombination is impaired in Atm-deficient mice. J. Exp. Med. 200:1111-1121.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1111-1121
-
-
Lumsden, J.M.1
McCarty, T.2
Petiniot, L.K.3
Shen, R.4
Barlow, C.5
Wynn, T.A.6
Morse III, H.C.7
Gearhart, P.J.8
Wynshaw-Boris, A.9
Max, E.E.10
Hodes, R.J.11
-
12
-
-
0035818990
-
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
-
Petersen, S., R. Casellas, B. Reina-San-Martin, H.T. Chen, M.J. Difilippantonio, P.C. Wilson, L. Hanitsch, A. Celeste, M. Muramatsu, D.R. Pilch, et al. 2001. AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching. Nature. 414:660-665.
-
(2001)
Nature
, vol.414
, pp. 660-665
-
-
Petersen, S.1
Casellas, R.2
Reina-San-Martin, B.3
Chen, H.T.4
Difilippantonio, M.J.5
Wilson, P.C.6
Hanitsch, L.7
Celeste, A.8
Muramatsu, M.9
Pilch, D.R.10
-
13
-
-
1942437416
-
Delineation of the role of the Mre11 complex in class switch recombination
-
Lähdesmäki, A., A.M. Taylor, K.H. Chrzanowska, and Q. Pan-Hammarström. 2004. Delineation of the role of the Mre11 complex in class switch recombination. J. Biol. Chem. 279:16479-16487.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16479-16487
-
-
Lähdesmäki, A.1
Taylor, A.M.2
Chrzanowska, K.H.3
Pan-Hammarström, Q.4
-
14
-
-
13444309097
-
Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs 1
-
Reina-San-Martin, B., M.C. Nussenzweig, A. Nussenzweig, and S. Difilippantonio. 2005. Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs 1. Proc. Natl. Acad. Sci. USA. 102:1590-1595.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1590-1595
-
-
Reina-San-Martin, B.1
Nussenzweig, M.C.2
Nussenzweig, A.3
Difilippantonio, S.4
-
15
-
-
13444281917
-
Nibrin functions in Ig class-switch recombination
-
Kracker, S., Y. Bergmann, I. Demuth, P.O. Frappart, G. Hildebrand, R. Christine, Z.Q. Wang, K. Sperling, M. Digweed, and A. Radbruch. 2005. Nibrin functions in Ig class-switch recombination. Proc. Natl. Acad. Sci. USA. 102:1584-1589.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1584-1589
-
-
Kracker, S.1
Bergmann, Y.2
Demuth, I.3
Frappart, P.O.4
Hildebrand, G.5
Christine, R.6
Wang, Z.Q.7
Sperling, K.8
Digweed, M.9
Radbruch, A.10
-
16
-
-
0037866984
-
H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation
-
Reina-San-Martin, B., S. Difilippantonio, L. Hanitsch, R.F. Masilamani, A. Nussenzweig, and M.C. Nussenzweig. 2003. H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation. J. Exp. Med. 197:1767-1778.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1767-1778
-
-
Reina-San-Martin, B.1
Difilippantonio, S.2
Hanitsch, L.3
Masilamani, R.F.4
Nussenzweig, A.5
Nussenzweig, M.C.6
-
17
-
-
2442707746
-
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
-
Manis, J.P., J.C. Morales, Z. Xia, J.L. Kutok, F.W. Alt, and P.B. Carpenter. 2004. 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat. Immunol. 5:481-487.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 481-487
-
-
Manis, J.P.1
Morales, J.C.2
Xia, Z.3
Kutok, J.L.4
Alt, F.W.5
Carpenter, P.B.6
-
18
-
-
2542463148
-
53BP1 is required for class switch recombination
-
Ward, I.M., B. Reina-San-Martin, A. Olaru, K. Minn, K. Tamada, J.S. Lau, M. Cascalho, L. Chen, A. Nussenzweig, F. Livak, et al. 2004. 53BP1 is required for class switch recombination. J. Cell Biol. 165:459-464.
-
(2004)
J. Cell Biol.
, vol.165
, pp. 459-464
-
-
Ward, I.M.1
Reina-San-Martin, B.2
Olaru, A.3
Minn, K.4
Tamada, K.5
Lau, J.S.6
Cascalho, M.7
Chen, L.8
Nussenzweig, A.9
Livak, F.10
-
19
-
-
0030273141
-
The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching
-
Rolink, A., F. Melchers, and J. Andersson. 1996. The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching. Immunity. 5:319-330.
-
(1996)
Immunity.
-
-
Rolink, A.1
Melchers, F.2
Andersson, J.3
-
20
-
-
0036224604
-
IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells
-
Manis, J.P., D. Dudley, L. Kaylor, and F.W. Alt. 2002. IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells. Immunity. 16:607-617.
-
(2002)
Immunity
, vol.16
, pp. 607-617
-
-
Manis, J.P.1
Dudley, D.2
Kaylor, L.3
Alt, F.W.4
-
21
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham, R.T. 2001. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15:2177-2196.
-
(2001)
Genes Dev.
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
22
-
-
0034177408
-
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
-
de Klein, A., M. Muijtjens, R. van Os, Y. Verhoeven, B. Smit, A.M. Carr, A.R. Lehmann, and J.H. Hoeijmakers. 2000. Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice. Curr. Biol. 10:479-482.
-
(2000)
Curr. Biol.
, vol.10
, pp. 479-482
-
-
De Klein, A.1
Muijtjens, M.2
Van Os, R.3
Verhoeven, Y.4
Smit, B.5
Carr, A.M.6
Lehmann, A.R.7
Hoeijmakers, J.H.8
-
23
-
-
0034102337
-
ATR disruption leads to chromosomal fragmentation and early embryonic lethality
-
Brown, E.J., and D. Baltimore. 2000. ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev. 14:397-402.
-
(2000)
Genes Dev.
, vol.14
, pp. 397-402
-
-
Brown, E.J.1
Baltimore, D.2
-
24
-
-
0037377943
-
ATM is not required in somatic hypermutation of VH, but is involved in the in troduction of mutations in the switch μ region
-
Pan-Hammarström, Q., S. Dai, Y. Zhao, I.F. van Dijk-Härd, R.A. Gatti, A.L. Børresen-Dale, and L. Hammarström. 2003. ATM is not required in somatic hypermutation of VH, but is involved in the in troduction of mutations in the switch μ region. J. Immunol. 170:3707-3716.
-
(2003)
J. Immunol.
, vol.170
, pp. 3707-3716
-
-
Pan-Hammarström, Q.1
Dai, S.2
Zhao, Y.3
Van Dijk-Härd, I.F.4
Gatti, R.A.5
Børresen-Dale, A.L.6
Hammarström, L.7
-
25
-
-
0034694086
-
Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity
-
Bemark, M., J.E. Sale, H.J. Kim, C. Berek, R.A. Cosgrove, and M.S. Neuberger. 2000. Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity. J. Exp. Med. 192:1509-1514.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1509-1514
-
-
Bemark, M.1
Sale, J.E.2
Kim, H.J.3
Berek, C.4
Cosgrove, R.A.5
Neuberger, M.S.6
-
26
-
-
0345073699
-
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
-
O'Driscoll, M., V.L. Ruiz-Perez, C.G. Woods, P.A. Jeggo, and J.A. Goodship. 2003. A splicing mutation affecting expression of ataxia- telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat. Genet. 33:497-501.
-
(2003)
Nat. Genet.
, vol.33
, pp. 497-501
-
-
O'Driscoll, M.1
Ruiz-Perez, V.L.2
Woods, C.G.3
Jeggo, P.A.4
Goodship, J.A.5
-
27
-
-
0242678554
-
Chromosome instability induced in vitro with mitomycin C in five Seckel syndrome patients
-
Bobabilla-Morales, L., A. Corona-Rivera, J.R. Corona-Rivera, C. Buenrostro, T.A. Garcia-Cobian, E. Corona-Rivera, J.M. Cantu-Garza, and D. Garcia-Cruz. 2003. Chromosome instability induced in vitro with mitomycin C in five Seckel syndrome patients. Am. J. Med. Genet. A. 123:148-152.
-
(2003)
Am. J. Med. Genet. A
, vol.123
, pp. 148-152
-
-
Bobabilla-Morales, L.1
Corona-Rivera, A.2
Corona-Rivera, J.R.3
Buenrostro, C.4
Garcia-Cobian, T.A.5
Corona-Rivera, E.6
Cantu-Garza, J.M.7
Garcia-Cruz, D.8
-
28
-
-
4544333154
-
Chromosomal instability at common fragile sites in Seckel syndrome
-
Casper, A.M., S.G. Durkin, M.F. Arlt, and T.W. Glover. 2004. Chromosomal instability at common fragile sites in Seckel syndrome. Am. J. Hum. Genet. 75:654-660.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 654-660
-
-
Casper, A.M.1
Durkin, S.G.2
Arlt, M.F.3
Glover, T.W.4
-
29
-
-
0028082234
-
Acute myeloid leukaemia in a patient with Seckel syndrome
-
Hayani, A., C.R. Suarez, Z. Molnar, M. LeBeau, and J. Godwin. 1994. Acute myeloid leukaemia in a patient with Seckel syndrome. J. Med. Genet. 31:148-149.
-
(1994)
J. Med. Genet.
, vol.31
, pp. 148-149
-
-
Hayani, A.1
Suarez, C.R.2
Molnar, Z.3
LeBeau, M.4
Godwin, J.5
-
30
-
-
0035666864
-
Regulation of switching and production of IgA in human B cells in donors with duplicated a1 genes
-
Pan, Q., C. Petit-Frere, S. Dai, P. Huang, H.C. Morton, P. Brandtzaeg, and L. Hammarström. 2001. Regulation of switching and production of IgA in human B cells in donors with duplicated a1 genes. Eur. J. Immunol. 31:3622-3630.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 3622-3630
-
-
Pan, Q.1
Petit-Frere, C.2
Dai, S.3
Huang, P.4
Morton, H.C.5
Brandtzaeg, P.6
Hammarström, L.7
-
31
-
-
0027227311
-
Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes
-
Betz, A.G., M.S. Neuberger, and C. Milstein. 1993. Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunol. Today. 14:405-411.
-
(1993)
Immunol. Today
, vol.14
, pp. 405-411
-
-
Betz, A.G.1
Neuberger, M.S.2
Milstein, C.3
-
33
-
-
0035379581
-
Somatic mutation hotspots correlate with DNA polymerase η error spectrum
-
Rogozin, I.B., Y.I. Pavlov, K. Bebenek, T. Matsuda, and T.A. Kunkel. 2001. Somatic mutation hotspots correlate with DNA polymerase η error spectrum. Nat. Immunol. 2:530-536.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 530-536
-
-
Rogozin, I.B.1
Pavlov, Y.I.2
Bebenek, K.3
Matsuda, T.4
Kunkel, T.A.5
-
34
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh, Y. 2003. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer. 3:155-168.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
35
-
-
0035253615
-
ATM and ATR: Networking cellular responses to DNA damage
-
Shiloh, Y. 2001. ATM and ATR: networking cellular responses to DNA damage. Curr. Opin. Genet. Dev. 11:71-77.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 71-77
-
-
Shiloh, Y.1
-
36
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts, R.S., K.M. Brumbaugh, J.M. Williams, J.N. Sarkaria, W.A. Cliby, S.Y. Shieh, Y. Taya, C. Prives, and R.T. Abraham. 1999. A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev. 13:152-157.
-
(1999)
Genes Dev.
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
37
-
-
4944242445
-
DNA damage induced by temozolomide signals to both ATM and ATR: Role of the mismatch repair system
-
Caporali, S., S. Falcinelli, G. Starace, M.T. Russo, E. Bonmassar, J. Jiricny, and S. D'Atri. 2004. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system. Mol. Pharmacol. 66:478-491.
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 478-491
-
-
Caporali, S.1
Falcinelli, S.2
Starace, G.3
Russo, M.T.4
Bonmassar, E.5
Jiricny, J.6
D'Atri, S.7
-
38
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
Cortez, D., S. Guntuku, J. Qin, and S.J. Elledge. 2001. ATR and ATRIP: partners in checkpoint signaling. Science. 294:1713-1716.
-
(2001)
Science
, vol.294
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
39
-
-
0031278299
-
Ig Sγ3 DNA-specifc double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination
-
Wuerffel, R.A., J. Du, R.J. Thompson, and A.L. Kenter. 1997. Ig Sγ3 DNA-specifc double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination. J. Immunol. 159:4139-4144.
-
(1997)
J. Immunol.
, vol.159
, pp. 4139-4144
-
-
Wuerffel, R.A.1
Du, J.2
Thompson, R.J.3
Kenter, A.L.4
-
40
-
-
0036732772
-
AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line
-
Faili, A., S. Aoufouchi, Q. Gueranger, C. Zober, A. Leon, B. Bertocci, J.C. Weill, and C.A. Reynaud. 2002. AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line. Nat. Immunol. 3:815-821.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 815-821
-
-
Faili, A.1
Aoufouchi, S.2
Gueranger, Q.3
Zober, C.4
Leon, A.5
Bertocci, B.6
Weill, J.C.7
Reynaud, C.A.8
-
41
-
-
0347758541
-
The generation of antibody diversity through somatic hypermutation and class switch recombination
-
Li, Z., C.J. Woo, M.D. Iglesias-Ussel, D. Ronai, and M.D. Scharff . 2004. The generation of antibody diversity through somatic hypermutation and class switch recombination. Genes Dev. 18:1-11.
-
(2004)
Genes Dev.
, vol.18
, pp. 1-11
-
-
Li, Z.1
Woo, C.J.2
Iglesias-Ussel, M.D.3
Ronai, D.4
Scharff, M.D.5
-
42
-
-
13444259474
-
Somatic hypermutation at A.T pairs: Polymerase error versus dUTP incorporation
-
Neuberger, M.S., J.M. Di Noia, R.C. Beale, G.T. Williams, Z. Yang, and C. Rada. 2005. Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation. Nat. Rev. Immunol. 5:171-178.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 171-178
-
-
Neuberger, M.S.1
Di Noia, J.M.2
Beale, R.C.3
Williams, G.T.4
Yang, Z.5
Rada, C.6
-
43
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou, L., and S.J. Elledge. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science. 300:1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
44
-
-
4344700569
-
Replication protein a interacts with AID to promote deamination of somatic hypermutation targets
-
Chaudhuri, J., C. Khuong, and F.W. Alt. 2004. Replication protein A interacts with AID to promote deamination of somatic hypermutation targets. Nature. 430:992-998.
-
(2004)
Nature
, vol.430
, pp. 992-998
-
-
Chaudhuri, J.1
Khuong, C.2
Alt, F.W.3
-
45
-
-
13244268505
-
Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells
-
Pan-Hammarström, Q., A.M. Jones, A. Lähdesmäki, W. Zhou, R.A. Gatti, L. Hammarström, A.R. Gennery, and M.R. Ehrenstein. 2005. Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells. J. Exp. Med. 201:189-194.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 189-194
-
-
Pan-Hammarström, Q.1
Jones, A.M.2
Lähdesmäki, A.3
Zhou, W.4
Gatti, R.A.5
Hammarström, L.6
Gennery, A.R.7
Ehrenstein, M.R.8
-
46
-
-
0033603240
-
Sir-Ku-itous routes to make ends meet
-
Haber, J.E. 1999. Sir-Ku-itous routes to make ends meet. Cell. 97:829-832.
-
(1999)
Cell
, vol.97
, pp. 829-832
-
-
Haber, J.E.1
-
47
-
-
0033384508
-
Targeting of human switch recombination breakpoints: Implications for the mechanism of μ -γ isotype switching
-
Pan, Q., and L. Hammarström. 1999. Targeting of human switch recombination breakpoints: implications for the mechanism of μ -γ isotype switching. Eur. J. Immunol. 29:2779-2787.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 2779-2787
-
-
Pan, Q.1
Hammarström, L.2
-
48
-
-
0037017390
-
Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions
-
Schrader, C.E., J. Vardo, and J. Stavnezer. 2002. Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions. J. Exp. Med. 195:367-373.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 367-373
-
-
Schrader, C.E.1
Vardo, J.2
Stavnezer, J.3
-
49
-
-
12744259733
-
Activationinduced deaminase: Controversies and open questions
-
Barreto, V.M., A.R. Ramiro, and M.C. Nussenzweig. 2005. Activationinduced deaminase: controversies and open questions. Trends Immunol. 26:90-96.
-
(2005)
Trends Immunol.
, vol.26
, pp. 90-96
-
-
Barreto, V.M.1
Ramiro, A.R.2
Nussenzweig, M.C.3
-
50
-
-
2942744563
-
DNA stimulates Mec1-mediated phosphorylation of replication protein A
-
Bartrand, A.J., D. Iyasu, and G.S. Brush. 2004. DNA stimulates Mec1-mediated phosphorylation of replication protein A. J. Biol. Chem. 279:26762-26767.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26762-26767
-
-
Bartrand, A.J.1
Iyasu, D.2
Brush, G.S.3
-
51
-
-
0037665234
-
ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation
-
Barr, S.M., C.G. Leung, E.E. Chang, and K.A. Cimprich. 2003. ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation. Curr. Biol. 13:1047-1051.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1047-1051
-
-
Barr, S.M.1
Leung, C.G.2
Chang, E.E.3
Cimprich, K.A.4
-
52
-
-
3442896884
-
Replication protein a phosphorylation and the cellular response to DNA damage
-
Binz, S.K., A.M. Sheehan, and M.S. Wold. 2004. Replication protein A phosphorylation and the cellular response to DNA damage. DNA Repair (Amst.). 3:1015-1024.
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 1015-1024
-
-
Binz, S.K.1
Sheehan, A.M.2
Wold, M.S.3
-
53
-
-
4143051517
-
ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background
-
Fang, Y., C.C. Tsao, B.K. Goodman, R. Furumai, C.A. Tirado, R.T. Abraham, and X.F. Wang. 2004. ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background. EMBO J. 23:3164-3174.
-
(2004)
EMBO J.
, vol.23
, pp. 3164-3174
-
-
Fang, Y.1
Tsao, C.C.2
Goodman, B.K.3
Furumai, R.4
Tirado, C.A.5
Abraham, R.T.6
Wang, X.F.7
-
54
-
-
0347364654
-
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation
-
Wang, Y., and J. Qin. 2003. MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. Proc. Natl. Acad. Sci. USA. 100:15387-15392.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15387-15392
-
-
Wang, Y.1
Qin, J.2
-
55
-
-
0035377269
-
DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
-
Zeng, X., D.B. Winter, C. Kasmer, K.H. Kraemer, A.R. Lehmann, and P.J. Gearhart. 2001. DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes. Nat. Immunol. 2:537-541.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 537-541
-
-
Zeng, X.1
Winter, D.B.2
Kasmer, C.3
Kraemer, K.H.4
Lehmann, A.R.5
Gearhart, P.J.6
-
56
-
-
3142663166
-
A role for msh6 but not msh3 in somatic hypermutation and class switch recombination
-
Martomo, S.A., W.W. Yang, and P.J. Gearhart. 2004. A role for msh6 but not msh3 in somatic hypermutation and class switch recombination. J. Exp. Med. 200:61-68.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 61-68
-
-
Martomo, S.A.1
Yang, W.W.2
Gearhart, P.J.3
-
57
-
-
1642499721
-
DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination
-
Faili, A., S. Aoufouchi, S. Weller, F. Vuillier, A. Stary, A. Sarasin, C.A. Reynaud, and J.C. Weill. 2004. DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination. J. Exp. Med. 199:265-270.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 265-270
-
-
Faili, A.1
Aoufouchi, S.2
Weller, S.3
Vuillier, F.4
Stary, A.5
Sarasin, A.6
Reynaud, C.A.7
Weill, J.C.8
-
58
-
-
20444427642
-
DNA polymerase η contributes to strand bias of mutations of a versus T in immunoglobulin genes
-
Mayorov, V.I., I.B. Rogozin, L.R. Adkison, and P.J. Gearhart. 2005. DNA polymerase η contributes to strand bias of mutations of A versus T in immunoglobulin genes. J. Immunol. 174:7781-7786.
-
(2005)
J. Immunol.
, vol.174
, pp. 7781-7786
-
-
Mayorov, V.I.1
Rogozin, I.B.2
Adkison, L.R.3
Gearhart, P.J.4
-
59
-
-
0032435650
-
TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line
-
Sale, J.E., and M.S. Neuberger. 1998. TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line. Immunity. 9:859-869.
-
(1998)
Immunity
, vol.9
, pp. 859-869
-
-
Sale, J.E.1
Neuberger, M.S.2
-
60
-
-
0034813325
-
Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line
-
Zhang, W., P.D. Bardwell, C.J. Woo, V. Poltoratsky, M.D. Scharff , and A. Martin. 2001. Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line. Int. Immunol. 13:1175-1184.
-
(2001)
Int. Immunol.
, vol.13
, pp. 1175-1184
-
-
Zhang, W.1
Bardwell, P.D.2
Woo, C.J.3
Poltoratsky, V.4
Scharff, M.D.5
Martin, A.6
-
61
-
-
1342282983
-
DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine
-
Yu, K., F.T. Huang, and M.R. Lieber. 2004. DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine. J. Biol. Chem. 279:6496-6500.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 6496-6500
-
-
Yu, K.1
Huang, F.T.2
Lieber, M.R.3
-
62
-
-
0037926476
-
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation
-
Pham, P., R. Bransteitter, J. Petruska, and M.F. Goodman. 2003. Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation. Nature. 424:103-107.
-
(2003)
Nature
, vol.424
, pp. 103-107
-
-
Pham, P.1
Bransteitter, R.2
Petruska, J.3
Goodman, M.F.4
-
63
-
-
0034750010
-
A new locus for Seckel syndrome on chromosome 18p11.31-q11. 2
-
Borglum, A.D., T. Balslev, A. Haagerup, N. Birkebaek, H. Binderup, T.A. Kruse, and J.M. Hertz. 2001. A new locus for Seckel syndrome on chromosome 18p11.31-q11. 2. Eur. J. Hum. Genet. 9:753-757.
-
(2001)
Eur. J. Hum. Genet.
, vol.9
, pp. 753-757
-
-
Borglum, A.D.1
Balslev, T.2
Haagerup, A.3
Birkebaek, N.4
Binderup, H.5
Kruse, T.A.6
Hertz, J.M.7
-
64
-
-
18644367647
-
Clinical and genetic heterogeneity of Seckel syndrome
-
Faivre, L., M. Le Merrer, S. Lyonnet, H. Plauchu, N. Dagoneau, A.B. Campos-Xavier, J. Attia-Sobol, A. Verloes, A. Munnich, and V. Cormier-Daire. 2002. Clinical and genetic heterogeneity of Seckel syndrome. Am. J. Med. Genet. 112:379-383.
-
(2002)
Am. J. Med. Genet.
, vol.112
, pp. 379-383
-
-
Faivre, L.1
Le Merrer, M.2
Lyonnet, S.3
Plauchu, H.4
Dagoneau, N.5
Campos-Xavier, A.B.6
Attia-Sobol, J.7
Verloes, A.8
Munnich, A.9
Cormier-Daire, V.10
-
65
-
-
0242441476
-
Is the novel SCKL3 at 14q23 the predominant Seckel locus?
-
Kilinc, M.O., V.N. Ninis, S.A. Ugur, B. Tuysuz, M. Seven, S. Balci, J. Goodship, and A. Tolun. 2003. Is the novel SCKL3 at 14q23 the predominant Seckel locus? Eur. J. Hum. Genet. 11:851-857.
-
(2003)
Eur. J. Hum. Genet.
, vol.11
, pp. 851-857
-
-
Kilinc, M.O.1
Ninis, V.N.2
Ugur, S.A.3
Tuysuz, B.4
Seven, M.5
Balci, S.6
Goodship, J.7
Tolun, A.8
-
66
-
-
0033853562
-
Autozygosity mapping of a Seckel syndrome locus to chromosome 3q22. 1-q24
-
Goodship, J., H. Gill, J. Carter, A. Jackson, M. Splitt, and M. Wright. 2000. Autozygosity mapping of a Seckel syndrome locus to chromosome 3q22. 1-q24. Am. J. Hum. Genet. 67:498-503.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 498-503
-
-
Goodship, J.1
Gill, H.2
Carter, J.3
Jackson, A.4
Splitt, M.5
Wright, M.6
-
67
-
-
11044234004
-
Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway
-
Alderton, G.K., H. Joenje, R. Varon, A.D. Borglum, P.A. Jeggo, and M. O'Driscoll. 2004. Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway. Hum. Mol. Genet. 13:3127-3138.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 3127-3138
-
-
Alderton, G.K.1
Joenje, H.2
Varon, R.3
Borglum, A.D.4
Jeggo, P.A.5
O'Driscoll, M.6
-
68
-
-
0031570509
-
Allotype-associated variation in the human γ3 switch region as a basis for differences in IgG3 production
-
Pan, Q., H. Rabbani, F.C. Mills, E. Severinson, and L. Hammarström. 1997. Allotype-associated variation in the human γ3 switch region as a basis for differences in IgG3 production. J. Immunol. 158:5849-5859.
-
(1997)
J. Immunol.
, vol.158
, pp. 5849-5859
-
-
Pan, Q.1
Rabbani, H.2
Mills, F.C.3
Severinson, E.4
Hammarström, L.5
-
69
-
-
0035166917
-
IMGT, the international ImMunoGeneTics database
-
Lefranc, M.P. 2001. IMGT, the international ImMunoGeneTics database. Nucleic Acids Res. 29:207-209.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 207-209
-
-
Lefranc, M.P.1
|