The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: Implications for the Mre11 complex as a DNA damage sensor

Genes and Development

Volumn 19, Issue 24, 2005, Pages 3043-3054

  Morales, Monica ^a   Theunissen, Jan Willem F ^a   Bender Kim, Carla F ^b   Kitagawa, Risa ^c   Kastan, Michael B ^c   Petrini, John H J ^a  

^a Weill Cornell Graduate School of Biomedical Sciences   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Apoptosis; Checkpoints; DNA damage signaling

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 2; MRE11 PROTEIN; NIBRIN; PROTEIN; RAD50 PROTEIN; ABC TRANSPORTER; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; MRE11A PROTEIN, MOUSE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN SERINE THREONINE KINASE; RAD50 PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ALLELE; ANIMAL CELL; APOPTOSIS; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; HEMATOPOIETIC CELL; KNOCKOUT MOUSE; MAMMAL; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MALE; METABOLISM; MOUSE MUTANT;

ANIMALIA; ATAXIA TELANGIECTASIA; MAMMALIA; SACCHAROMYCES CEREVISIAE;

ALLELES; ANIMALS; APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; CELL CYCLE PROTEINS; CELLS, CULTURED; DNA DAMAGE; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; MALE; MICE; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 29144450333     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1373705     Document Type: Article

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