Repair of topoisomerase-mediated DNA damage in bacteriophage T4

Genetics

Volumn 158, Issue 1, 2001, Pages 19-28

  Onda, Masaaki ^a,c   Yamaguchi, Junko ^a   Hanada, Katsuhiro ^b   Asami, Yasuo ^b   Ikeda, Hideo ^a  

^a KITASATO INSTITUTE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c Funakoshi Co Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMSACRINE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA; ENDONUCLEASE; GYRASE INHIBITOR;

ARTICLE; BACTERIOPHAGE T4; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA CLEAVAGE; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME ACTIVE SITE; GENETIC ANALYSIS; NONHUMAN; PLASMID; PRIORITY JOURNAL;

AMSACRINE; BACTERIOPHAGE T4; BASE SEQUENCE; DNA DAMAGE; DNA PRIMERS; DNA REPAIR; DNA TOPOISOMERASES, TYPE II; DNA, VIRAL; MUTATION; PLASMIDS; RECOMBINATION, GENETIC;

EID: 0035011556     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Site-specific cleavage of bacteriophage T4 DNA associated with the absence of gene 46 product function
2. Plasmid models for bacteriophage T4 DNA replication: Requirements for fork proteins
3. Type II DNA topoisomerases
4. Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme
5. DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II
6. DNA topoisomerases: Essential enzymes and lethal targets
7. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons
8. Expression and function of the uvsW gene of bacteriophage T4
9. DNA gyrase, topoisomerase IV, and the 4-quinolones
10. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin
11. Secondary leukemias induced by topoisomerase-targeted drugs
12. Links between replication, recombination and genome instability in eukaryotes
13. Purification and characterization of the T4 bacteriophage uvsX protein
14. Mutational analysis of a type II topoisomerase cleavage site: Distinct requirements for enzyme and inhibitors
15. Mutations of the bacteriophage T4 type II DNA topoisomerase that alter sensitivity to antitumor agent 4′-(9-acridinylamino)methanesulfon-m-anisidide and an antibacterial quinolone
16. Repair of double-strand breaks in bacteriophage T4 by a mechanism that involves extensive DNA replication
17. DNA strand cleavage is required for replication fork arrest by a frozen topoisomerase-quinolone-DNA ternary complex
18. Cloning of the bacteriophage T4 uvsXgene and purification and characterization of the T4 uvsX recombination protein
19. Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells
20. An antitumor drug-induced topoisomerase cleavage complex blocks a bacteriophage T4 replication fork in vivo
21. Clinical applications of quinolones
22. Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase
23. Role of exonucleolytic degradation in group I intron homing in phage T4
24. Sensitivity of Chinese hamster ovary, mutants defective in DNA double strand break repair to topoisomerase II inhibitors
25. The phage T4 uvsY recombination protein stabilizes presynaptic filaments
26. Bacteriophage T4, a model system for understanding the mechanism of type II topoisomerase inhibitors
27. Recombination-dependent DNA replication in phage T4
28. Escherichia coli mutants thermosensitive for deoxyribonucleic acid gyrase subunit A: Effects on deoxyribonucleic acid replication, transcription, and bacteriophage growth
29. Repair of lethal DNA damage
30. Tertiary initiation of replication in bacteriophage T4. Deletion of the overlapping uvsY promoter/replication origin from the phage genome
31. Recombination-dependent DNA replication stimulated by double-strand breaks in bacteriophage T4
32. 4-Quinolones and the SOS response
33. Homology-directed repair is a major double-strand break repair pathway in mammalian cells
34. - recipient strains of Escherichia coli K12
35. Fate of cloned bacteriophage T4 DNA after phage T4 infection of clone-bearing cells
36. Survival of recombination-deficient mutants of Escherichia coli during incubation with nalidixic acid
37. DNA double-strand breaks caused by replication arrest
38. T4 endonuclease VII cleaves Holiday structures
39. The uvsY protein of bacteriophage T4 modulates recombination-dependent DNA synthesis in vitro
40. Exon coconversion biases accompanying intron homing: Battle of the nucleases
41. Role of recombinational repair in sensitivity to an antitumor agent that inhibits bacteriophage T4 type II DNA topoisomerase
42. Multidrug efflux pumps of gram-negative bacteria
43. DNA topoisomerase-targeting antitumor drugs can be studied in yeast
44. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
45. Sister chromatid exchanges, chromosomal aberrations, and cytotoxicity produced by antitumor topoisomerase II inhibitors in sensitive (DC3F) and resistant (DC3F/9-OHE) Chinese hamster cells
46. Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes
47. Mechanisms for the processing of a frozen topoisomerase-DNA conjugate by human cell-free extracts
48. The bacteriophage T4 insertion/substitution vector system. A method for introducing site-specific mutations into the virus chromosome
49. Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast
50. The double-strand-break repair model for recombination
51. The role of homologous recombination processes in the repair of severe forms of DNA damage in mammalian cells
52. Influence of recA mutations on gyrA dependent quinolone resistance
53. DNA topoisomerases
54. Cell-cycle-stage specificity of 4′-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) and interaction with ionizing radiation in mammalian cell cultures
55. A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases
56. T4 phage gene uvsX product catalyzes homologous DNA pairing
57. Synergistic action of three recombination gene products of bacteriophage T4, uvsX, nvsY, and gene 32 proteins