The Discovery of the CCR5 Receptor Antagonist, UK-427,857, A New Agent for the Treatment of HIV Infection and AIDS

Progress in Medicinal Chemistry

Volumn 43, Issue C, 2005, Pages 239-271

  Wood, Anthony ^a   Armour, Duncan ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4,4 DIFLUORO N ((1S) 3 (EXO 3 (3 ISOPROPYL 5 METHYL 4H 1,2,4 TRIAZOL 4 YL) 8 AZABICYCLO(3.2.1)OCT 8 YL) 1 PHENYLPROPYL)CYCLOHEXANECARBOXAMIDE; 4,4-DIFLUORO-N-((1S)-3-(EXO-3-(3-ISOPROPYL-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)-8-AZABICYCLO(3.2.1)OCT-8-YL)-1-PHENYLPROPYL)CYCLOHEXANECARBOXAMIDE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CHEMOKINE RECEPTOR CCR5; CYCLOHEXANE DERIVATIVE; MACROPHAGE INFLAMMATORY PROTEIN 1; TRIAZOLE DERIVATIVE; VIRUS RECEPTOR;

ANIMAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; PROTEIN BINDING; RADIOASSAY; REVIEW;

ANIMALS; ANTI-HIV AGENTS; CYCLOHEXANES; HUMANS; MACROPHAGE INFLAMMATORY PROTEIN-1; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, CCR5; RECEPTORS, HIV; TRIAZOLES;

EID: 27744548649     PISSN: 00796468     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6468(05)43007-6     Document Type: Review

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