Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 co-receptor and ligand binding function

Journal of Biological Chemistry

Volumn 274, Issue 23, 1999, Pages 16228-16234

  Howard, O M Zack ^a,d   Shirakawa, Aiko Konno ^b   Turpin, Jim A ^c   Maynard, Andrew ^a   Tobin, Gregory J ^a   Carrington, Mary ^a   Oppenheim, Joost J ^b   Dean, Michael ^b  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SOUTHERN RESEARCH INSTITUTE   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; RANTES; VIRUS RECEPTOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CELLULAR DISTRIBUTION; CHEMOTAXIS; DESENSITIZATION; GENE MUTATION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; VIRUS INHIBITION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CELL LINE; FLOW CYTOMETRY; HIV-1; HUMANS; LIGANDS; MACROPHAGE INFLAMMATORY PROTEIN-1; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NAPHTHALENESULFONATES; PROTEIN STRUCTURE, SECONDARY; RANTES; RECEPTORS, CCR5; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0033523018     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.23.16228     Document Type: Article

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