-
1
-
-
0030890586
-
Cellular responses to interferon-γ
-
Boehm U, Klamp T, Groot M, Howard JC. Cellular responses to interferon-γ. Ann. Rev. Immunol. 15, 749-795 (1997).
-
(1997)
Ann. Rev. Immunol.
, vol.15
, pp. 749-795
-
-
Boehm, U.1
Klamp, T.2
Groot, M.3
Howard, J.C.4
-
2
-
-
0026717674
-
The pathophysiology of tumor necrosis factors
-
Vassalli P. The pathophysiology of tumor necrosis factors. Ann. Rev. Immunol. 10, 411-452 (1992).
-
(1992)
Ann. Rev. Immunol.
, vol.10
, pp. 411-452
-
-
Vassalli, P.1
-
3
-
-
0141518343
-
Cytotoxic granule-mediated apoptosis: Unraveling the complex mechanism
-
Raja SM, Metkar SS, Froelich CJ. Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism. Curr. Opin. Immunol. 15, 528-532 (2003).
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 528-532
-
-
Raja, S.M.1
Metkar, S.S.2
Froelich, C.J.3
-
4
-
-
0027937745
-
Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
-
Lowin B, Hahne M, Mattmann C, Tschopp J. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 370, 650-652 (1994).
-
(1994)
Nature
, vol.370
, pp. 650-652
-
-
Lowin, B.1
Hahne, M.2
Mattmann, C.3
Tschopp, J.4
-
6
-
-
7444232558
-
CD8 T-cell memory
-
+ T-cells. The authors' point of view challenges many of the current dogmas in this field.
-
(2004)
Semin. Immunol.
, vol.16
, pp. 305-314
-
-
Rocha, B.1
Tanchot, C.2
-
7
-
-
0037074012
-
Molecular and functional profiling of memory CD8 T-cell differentiation
-
Kaech SM, Hemby S, Kersh E, Ahmed R. Molecular and functional profiling of memory CD8 T-cell differentiation. Cell 111, 837-851 (2002).
-
(2002)
Cell
, vol.111
, pp. 837-851
-
-
Kaech, S.M.1
Hemby, S.2
Kersh, E.3
Ahmed, R.4
-
9
-
-
0033658153
-
Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression
-
Sallusto F, Lanzavecchia A. Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression. Immunol. Rev. 177, 134-140 (2000).
-
(2000)
Immunol. Rev.
, vol.177
, pp. 134-140
-
-
Sallusto, F.1
Lanzavecchia, A.2
-
10
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired
-
Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired Immunity Nature Immunol. 2, 675-680 (2001).
-
(2001)
Immunity Nature Immunol.
, vol.2
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
11
-
-
2642631750
-
Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
-
Jonuleit H, Kuhn U, Muller G et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur. J. Immunol. 27, 3135-3142 (1997).
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 3135-3142
-
-
Jonuleit, H.1
Kuhn, U.2
Muller, G.3
-
14
-
-
10644269506
-
Cross-talk between dendritic cells and natural killer cells in viral infection
-
Andrews DM, Andoniou CE, Scalzo AA et al. Cross-talk between dendritic cells and natural killer cells in viral infection. Mol. Immunol. 42, 547-555 (2005).
-
(2005)
Mol. Immunol.
, vol.42
, pp. 547-555
-
-
Andrews, D.M.1
Andoniou, C.E.2
Scalzo, A.A.3
-
16
-
-
2942541735
-
Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens
-
Heath WR, Belz GT, Behrens GM et al. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol. Rev. 199, 9-26 (2004). Excellent review of the molecular basis of cross-presentation covering the most important aspects of this process, including the role of different populations of dendritic cells (DCs), the significance of cross-presentation in immunity and the potential use of this pathway of antigen presentation in vaccine design.
-
(2004)
Immunol. Rev.
, vol.199
, pp. 9-26
-
-
Heath, W.R.1
Belz, G.T.2
Behrens, G.M.3
-
18
-
-
4444288465
-
Stop and go traffic to tune T-cell responses
-
Dustin ML. Stop and go traffic to tune T-cell responses. Immunity 21, 305-314 (2004).
-
(2004)
Immunity
, vol.21
, pp. 305-314
-
-
Dustin, M.L.1
-
19
-
-
0346244099
-
T-cell-antigen recognition and the immunological synapse
-
Huppa JB, Davis MM. T-cell-antigen recognition and the immunological synapse. Nature Rev. Immunol. 3, 973-983 (2003).
-
(2003)
Nature Rev. Immunol.
, vol.3
, pp. 973-983
-
-
Huppa, J.B.1
Davis, M.M.2
-
20
-
-
0037385715
-
T-cell fitness determined by signal strength
-
Gett AV, Sallusto F, Lanzavecchia A, Geginat J. T-cell fitness determined by signal strength. Nature Immunol. 4, 355-360 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 355-360
-
-
Gett, A.V.1
Sallusto, F.2
Lanzavecchia, A.3
Geginat, J.4
-
21
-
-
0035292756
-
The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T-cell function
-
Coyle AJ, Gutierrez-Ramos JC. The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T-cell function. Nature Immunol. 2, 203-209 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 203-209
-
-
Coyle, A.J.1
Gutierrez-Ramos, J.C.2
-
22
-
-
0033746504
-
Activation induces rapid and profound alterations in the trafficking of T-cells
-
Hamann A, Klugewitz K, Austrup F, Jablonski-Westrich D. Activation induces rapid and profound alterations in the trafficking of T-cells. Eur. J. Immunol. 30, 3207-3218 (2000).
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 3207-3218
-
-
Hamann, A.1
Klugewitz, K.2
Austrup, F.3
Jablonski-Westrich, D.4
-
23
-
-
0036550559
-
Effector and memory T-cell differentiation: Implications for vaccine development
-
Kaech SM, Wherry EJ, Ahmed R. Effector and memory T-cell differentiation: implications for vaccine development. Nature Rev. Immunol. 2, 251-262 (2002).
-
(2002)
Nature Rev. Immunol.
, vol.2
, pp. 251-262
-
-
Kaech, S.M.1
Wherry, E.J.2
Ahmed, R.3
-
24
-
-
0032534058
-
Differentiation of naive CTL to effector and memory CTL: Correlation of effector function with phenotype and cell division
-
Oehen S, Brduscha-Riem K. Differentiation of naive CTL to effector and memory CTL: correlation of effector function with phenotype and cell division. J. Immunol. 161, 5338-5346 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 5338-5346
-
-
Oehen, S.1
Brduscha-Riem, K.2
-
25
-
-
0032007065
-
+ T-cells during an acute virus infection
-
+ T-cells during an acute virus infection. Immunity 8, 167-175 (1998).
-
(1998)
Immunity
, vol.8
, pp. 167-175
-
-
Butz, E.A.1
Bevan, M.J.2
-
26
-
-
0029112253
-
Induction of apoptosis in mature T-cells by tumour necrosis factor
-
Zheng L, Fisher G, Miller RE et al. Induction of apoptosis in mature T-cells by tumour necrosis factor. Nature 377, 348-351 (1995).
-
(1995)
Nature
, vol.377
, pp. 348-351
-
-
Zheng, L.1
Fisher, G.2
Miller, R.E.3
-
27
-
-
0036069819
-
Activated T-cell death in vivo mediated by proapoptotic bcl-2 family member bim
-
Hildeman DA, Zhu Y, Mitchell TC et al. Activated T-cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity 16, 759-767 (2002).
-
(2002)
Immunity
, vol.16
, pp. 759-767
-
-
Hildeman, D.A.1
Zhu, Y.2
Mitchell, T.C.3
-
30
-
-
0034027174
-
+ T-cell response is much less apparent following secondary challenge
-
+ T-cell response is much less apparent following secondary challenge. J. Virol. 74, 3486-3493 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 3486-3493
-
-
Belz, G.T.1
Xie, W.2
Altman, J.D.3
Doherty, P.C.4
-
31
-
-
0035348175
-
+ T-cell differentiation: Initial antigen encounter triggers a developmental program in naive cells
-
+ T-cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nature Immunol. 2, 415-422 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 415-422
-
-
Kaech, S.M.1
Ahmed, R.2
-
32
-
-
0030807248
-
+ T-cell can give rise to progeny expressing Type 1 and/or Type 2 cytokine genes and can retain its multipotentiality through many cell divisions
-
+ T-cell can give rise to progeny expressing Type 1 and/or Type 2 cytokine genes and can retain its multipotentiality through many cell divisions. Proc. Natl Acad. Sci. USA 94, 8070-8075 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 8070-8075
-
-
Kelso, A.1
Groves, P.2
-
33
-
-
0032482996
-
Cell division regulates the T-cell cytokine repertoire, revealing a mechanism underlying immune class regulation
-
Gett AV, Hodgkin PD. Cell division regulates the T-cell cytokine repertoire, revealing a mechanism underlying immune class regulation. Proc. Natl Acad. Sci. USA 95, 9488-9493 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 9488-9493
-
-
Gett, A.V.1
Hodgkin, P.D.2
-
36
-
-
0028020588
-
Generation of polarized antigen-specific CD8 effector populations: Reciprocal action of interleukin (IL)-4 and IL-12 in promoting Type 2 versus Type 1 cytokine profiles
-
Croft M, Carter L, Swain SL, Dutton RW. Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting Type 2 versus Type 1 cytokine profiles. J. Exp. Med. 180, 1715-1728 (1994).
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1715-1728
-
-
Croft, M.1
Carter, L.2
Swain, S.L.3
Dutton, R.W.4
-
37
-
-
0037083486
-
A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T-cells with low CD8, perforin, and granzyme expression
-
Kienzle N, Buttigieg K, Groves P, Kawula T, Kelso A. A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T-cells with low CD8, perforin, and granzyme expression. J. Immunol. 168, 1672-1681 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 1672-1681
-
-
Kienzle, N.1
Buttigieg, K.2
Groves, P.3
Kawula, T.4
Kelso, A.5
-
38
-
-
1842735268
-
Type 1 and Type 2 tumor infiltrating effector cell subpopulations in progressive breast cancer
-
Reome JB, Hylind JC, Dutton RW, Dobrzanski MJ. Type 1 and Type 2 tumor infiltrating effector cell subpopulations in progressive breast cancer. Clin. Immunol. 111, 69-81 (2004).
-
(2004)
Clin. Immunol.
, vol.111
, pp. 69-81
-
-
Reome, J.B.1
Hylind, J.C.2
Dutton, R.W.3
Dobrzanski, M.J.4
-
39
-
-
22544474190
-
CD8(+) T-cell contributions to allergen induced pulmonary inflammation and airway hyper-reactivity
-
Schaller MA, Lundy SK, Huffnagle GB, Lukacs NW. CD8(+) T-cell contributions to allergen induced pulmonary inflammation and airway hyper-reactivity. Eur. J. Immunol. (2005).
-
(2005)
Eur. J. Immunol.
-
-
Schaller, M.A.1
Lundy, S.K.2
Huffnagle, G.B.3
Lukacs, N.W.4
-
40
-
-
1642567230
-
Tc1 and Tc2 effector cell therapy elicit long-term tumor immunity by contrasting mechanisms that result in complementary endogenous Type 1 antitumor responses
-
Dobrzanski MJ, Reome JB, Hollenbaugh JA, Dutton RW. Tc1 and Tc2 effector cell therapy elicit long-term tumor immunity by contrasting mechanisms that result in complementary endogenous Type 1 antitumor responses. J. Immunol. 172, 1380-1390 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 1380-1390
-
-
Dobrzanski, M.J.1
Reome, J.B.2
Hollenbaugh, J.A.3
Dutton, R.W.4
-
42
-
-
0141629512
-
Nuclear war: The granzyme A-bomb
-
Lieberman J, Fan Z. Nuclear war: the granzyme A-bomb. Curr. Opin. Immunol. 15, 553-559 (2003).
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 553-559
-
-
Lieberman, J.1
Fan, Z.2
-
44
-
-
0038725690
-
The ABCs of granule-mediated cytotoxicity: New weapons in the arsenal
-
Lieberman J. The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal. Nature Rev. Immunol. 3, 361-370 (2003).
-
(2003)
Nature Rev. Immunol.
, vol.3
, pp. 361-370
-
-
Lieberman, J.1
-
45
-
-
0141629530
-
Granzyme B: Pro-apoptotic, antiviral and antitumor functions
-
Trapani JA, Sutton VR. Granzyme B: pro-apoptotic, antiviral and antitumor functions. Curr. Opin. Immunol. 15, 533-543 (2003).
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 533-543
-
-
Trapani, J.A.1
Sutton, V.R.2
-
47
-
-
0038281338
-
Cell death induced by granzyme C
-
Johnson H, Scorrano L, Korsmeyer SJ, Ley TJ. Cell death induced by granzyme C. Blood 101, 3093-3101 (2003).
-
(2003)
Blood
, vol.101
, pp. 3093-3101
-
-
Johnson, H.1
Scorrano, L.2
Korsmeyer, S.J.3
Ley, T.J.4
-
48
-
-
5644238762
-
Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
-
Grossman WJ, Verbsky JW, Tollefsen BL et al. Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood 104, 2840-2848 (2004).
-
(2004)
Blood
, vol.104
, pp. 2840-2848
-
-
Grossman, W.J.1
Verbsky, J.W.2
Tollefsen, B.L.3
-
50
-
-
0027937374
-
Heterogeneity of single cell cytokine gene expression in clonal T-cell populations
-
Bucy RP, Panoskaltsis-Mortari A, Huang GQ et al. Heterogeneity of single cell cytokine gene expression in clonal T-cell populations. J. Exp. Med. 180, 1251-1262 (1994).
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1251-1262
-
-
Bucy, R.P.1
Panoskaltsis-Mortari, A.2
Huang, G.Q.3
-
51
-
-
0035884779
-
Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) Type 1 and Type 2 T-cells
-
Chtanova T, Kemp RA, Sutherland AP, Ronchese F, Mackay CR. Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) Type 1 and Type 2 T-cells. J. Immunol. 167, 3057-3063 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 3057-3063
-
-
Chtanova, T.1
Kemp, R.A.2
Sutherland, A.P.3
Ronchese, F.4
Mackay, C.R.5
-
52
-
-
0345505645
-
Distinct thresholds for CD8 T-cell activation lead to functional heterogeneity: CD8 T-cell priming can occur independently of cell division
-
Auphan-Anezin N, Verdeil G, Schmitt-Verhulst AM. Distinct thresholds for CD8 T-cell activation lead to functional heterogeneity: CD8 T-cell priming can occur independently of cell division. J. Immunol. 170, 2442-2448 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 2442-2448
-
-
Auphan-Anezin, N.1
Verdeil, G.2
Schmitt-Verhulst, A.M.3
-
54
-
-
0028982517
-
Th1 and Th2 subsets: Paradigms lost?
-
Kelso A, Th1 and Th2 subsets: paradigms lost? Immunol. Today 16, 374-379 (1995).
-
(1995)
Immunol. Today
, vol.16
, pp. 374-379
-
-
Kelso, A.1
-
55
-
-
1642298007
-
low phenotype, an alternative career choice for CD8 T-cells during primary differentiation
-
low phenotype, an alternative career choice for CD8 T-cells during primary differentiation. Immunol. Cell Biol. 82, 75-83 (2004).
-
(2004)
Immunol. Cell Biol.
, vol.82
, pp. 75-83
-
-
Kienzle, N.1
Baz, A.2
Kelso, A.3
-
56
-
-
0038107576
-
Cutting edge: Granzymes A and B are not essential for perforin-mediated tumor rejection
-
Smyth MJ, Street SE, Trapani JA. Cutting edge: granzymes A and B are not essential for perforin-mediated tumor rejection. J. Immunol. 171, 515-518 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 515-518
-
-
Smyth, M.J.1
Street, S.E.2
Trapani, J.A.3
-
57
-
-
0033554726
-
Two subsets of memory T-lymphocytes with distinct homing potentials and effector functions
-
Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T-lymphocytes with distinct homing potentials and effector functions. Nature 401, 708-712 (1999).
-
(1999)
Nature
, vol.401
, pp. 708-712
-
-
Sallusto, F.1
Lenig, D.2
Forster, R.3
Lipp, M.4
Lanzavecchia, A.5
-
58
-
-
0037340417
-
Lineage relationship and protective immunity of memory CD8 T-cell subsets
-
Wherry EJ, Teichgraber V, Becker TC et al. Lineage relationship and protective immunity of memory CD8 T-cell subsets. Nature Immunol. 4, 225-234 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 225-234
-
-
Wherry, E.J.1
Teichgraber, V.2
Becker, T.C.3
-
60
-
-
0347382593
-
Selective expression of the interleukin-7 receptor identifies effector CD8 T-cells that give rise to long-lived memory cells
-
Kaech SM, Tan JT, Wherry EJ et al. Selective expression of the interleukin-7 receptor identifies effector CD8 T-cells that give rise to long-lived memory cells. Nature Immunol. 4, 1191-1198 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 1191-1198
-
-
Kaech, S.M.1
Tan, J.T.2
Wherry, E.J.3
-
61
-
-
2142756661
-
CD8αα-mediated survival and differentiation of CD8 memory T-cell precursors
-
Madakamutil LT, Christen U, Lena CJ et al. CD8αα-mediated survival and differentiation of CD8 memory T-cell precursors. Science 304, 590-593 (2004).
-
(2004)
Science
, vol.304
, pp. 590-593
-
-
Madakamutil, L.T.1
Christen, U.2
Lena, C.J.3
-
62
-
-
0037037568
-
Interleukin-15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T-cells
-
Judge AD, Zhang X, Fujii H, Surh CD, Sprent J. Interleukin-15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T-cells. J. Exp. Med. 196, 935-946 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 935-946
-
-
Judge, A.D.1
Zhang, X.2
Fujii, H.3
Surh, C.D.4
Sprent, J.5
-
64
-
-
0034599742
-
Differentiating between memory and effector CD8 T-cells by altered expression of cell surface O-glycans
-
Harrington LE, Galvan M, Baum LG, Altman JD, Ahmed R. Differentiating between memory and effector CD8 T-cells by altered expression of cell surface O-glycans. J. Exp. Med. 191, 1241-1246 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1241-1246
-
-
Harrington, L.E.1
Galvan, M.2
Baum, L.G.3
Altman, J.D.4
Ahmed, R.5
-
66
-
-
0037432776
-
Defective CD8 T-cell memory following acute infection without CD4 T-cell help
-
Sun JC, Bevan MJ. Defective CD8 T-cell memory following acute infection without CD4 T-cell help. Science 300, 339-342 (2003).
-
(2003)
Science
, vol.300
, pp. 339-342
-
-
Sun, J.C.1
Bevan, M.J.2
-
68
-
-
0032412441
-
Modulation of chromatin structure regulates cytokine gene expression during T-cell differentiation
-
Agarwal S, Rao A. Modulation of chromatin structure regulates cytokine gene expression during T-cell differentiation. Immunity 9, 765-775 (1998).
-
(1998)
Immunity
, vol.9
, pp. 765-775
-
-
Agarwal, S.1
Rao, A.2
-
70
-
-
0033548496
-
Linear differentiation of cytotoxic effectors into memory T-lymphocytes
-
Opferman JT, Ober BT, Ashton-Rickardt PG. Linear differentiation of cytotoxic effectors into memory T-lymphocytes. Science 283, 1745-1748 (1999).
-
(1999)
Science
, vol.283
, pp. 1745-1748
-
-
Opferman, J.T.1
Ober, B.T.2
Ashton-Rickardt, P.G.3
-
71
-
-
0035941095
-
Priming of memory but not effector CD8 T-cells by a killed bacterial vaccine
-
Lauvau G, Vijh S, Kong P et al. Priming of memory but not effector CD8 T-cells by a killed bacterial vaccine. Science 294, 1735-1739 (2001).
-
(2001)
Science
, vol.294
, pp. 1735-1739
-
-
Lauvau, G.1
Vijh, S.2
Kong, P.3
-
72
-
-
20244375369
-
Effector differentiation is not prerequisite for generation of memory cytotoxic T-lymphocytes
-
Manjunath N, Shankar P, Wan J et al. Effector differentiation is not prerequisite for generation of memory cytotoxic T-lymphocytes. J. Clin. Invest. 108, 871-878 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 871-878
-
-
Manjunath, N.1
Shankar, P.2
Wan, J.3
-
73
-
-
17244367884
-
Memory T-cells have gene expression patterns intermediate between naïve and effector
-
Holmes S, He M, Xu T, Lee PP. Memory T-cells have gene expression patterns intermediate between naïve and effector. Proc. Natl Acad. Sci. USA 102, 5519-5523 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 5519-5523
-
-
Holmes, S.1
He, M.2
Xu, T.3
Lee, P.P.4
-
75
-
-
0037432787
-
Requirement for CD4 T-cell help in generating functional CD8 T-cell memory
-
Shedlock DJ, Shen H. Requirement for CD4 T-cell help in generating functional CD8 T-cell memory. Science 300, 337-339 (2003).
-
(2003)
Science
, vol.300
, pp. 337-339
-
-
Shedlock, D.J.1
Shen, H.2
-
77
-
-
3142754938
-
Fully functional memory CD8 T-cells in the absence of CD4 T-cells
-
Marzo AL, Vezys V, Klonowski KD et al. Fully functional memory CD8 T-cells in the absence of CD4 T-cells. J. Immunol. 173, 969-975 (2004).
-
(2004)
J. Immunol.
, vol.173
, pp. 969-975
-
-
Marzo, A.L.1
Vezys, V.2
Klonowski, K.D.3
-
78
-
-
0032482337
-
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
-
Ridge JP, Di Rosa F, Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 393, 474-478 (1998).
-
(1998)
Nature
, vol.393
, pp. 474-478
-
-
Ridge, J.P.1
Di Rosa, F.2
Matzinger, P.3
-
79
-
-
0032482356
-
Help for cytotoxic-T-cell responses is mediated by CD40 signalling
-
Bennett SR, Carbone FR, Karamalis F et al. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 393, 478-480 (1998).
-
(1998)
Nature
, vol.393
, pp. 478-480
-
-
Bennett, S.R.1
Carbone, F.R.2
Karamalis, F.3
-
80
-
-
0031846313
-
CD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T-lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection
-
Borrow P, Tough DF, Eto D et al. CD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T-lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection. J. Virol. 72, 7440-7449 (1998).
-
(1998)
J. Virol.
, vol.72
, pp. 7440-7449
-
-
Borrow, P.1
Tough, D.F.2
Eto, D.3
-
82
-
-
1542724501
-
Cutting edge: Long-lived CD8 memory and protective immunity in the absence of CD40 expression on CD8 T-cells
-
Sun JC, Bevan MJ. Cutting edge: long-lived CD8 memory and protective immunity in the absence of CD40 expression on CD8 T-cells. J. Immunol. 172, 3385-3389 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 3385-3389
-
-
Sun, J.C.1
Bevan, M.J.2
-
83
-
-
14544288632
-
+ T-cell memory via TRAIL-mediated activation-induced cell death
-
+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature 434, 88-93 (2005).
-
(2005)
Nature
, vol.434
, pp. 88-93
-
-
Janssen, E.M.1
Droin, N.M.2
Lemmens, E.E.3
-
84
-
-
0344304408
-
Turning immunological memory into amnesia by depletion of dividing T-cells
-
Bellier B, Thomas-Vaslin V, Saron MF, Klatzmann D. Turning immunological memory into amnesia by depletion of dividing T-cells. Proc. Natl Acad. Sci. USA 100, 15017-15022 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 15017-15022
-
-
Bellier, B.1
Thomas-Vaslin, V.2
Saron, M.F.3
Klatzmann, D.4
-
86
-
-
0034633683
-
IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice
-
Marks-Konczalik J, Dubois S, Losi JM et al. IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice. Proc. Natl Acad. Sci. USA 97, 11445-11450 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 11445-11450
-
-
Marks-Konczalik, J.1
Dubois, S.2
Losi, J.M.3
-
91
-
-
0037472473
-
Tumor antigen-specific T-cells and cancer immunodierapy: Current issues and future prospects
-
Kalos M. Tumor antigen-specific T-cells and cancer immunodierapy: current issues and future prospects. J. Clin. Invest. 21, 781-786 (2003).
-
(2003)
J. Clin. Invest.
, vol.21
, pp. 781-786
-
-
Kalos, M.1
-
92
-
-
0842303169
-
New tools for antigen delivery to the MHC class I pathway
-
Moron G, Dadaglio G, Leclerc C. New tools for antigen delivery to the MHC class I pathway. Trends Immunol. 25, 92-97 (2004). Comprehensive review of different intracellular pathways leading to the presentation of pep tides in association with major histocompatibility complex (MHC) class I molecules. In addition to the classic endogeneous presentation pathway, pathogen components can access MHC class I molecules by other means. Such alternative mechanisms are clearly explained and their implications for vaccine development are discussed.
-
(2004)
Trends Immunol.
, vol.25
, pp. 92-97
-
-
Moron, G.1
Dadaglio, G.2
Leclerc, C.3
-
93
-
-
0037122719
-
Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus
-
Shiver JW, Fu TM, Chen L et al. Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus. Immunity Nature 415, 331-335 (2002).
-
(2002)
Immunity Nature
, vol.415
, pp. 331-335
-
-
Shiver, J.W.1
Fu, T.M.2
Chen, L.3
-
94
-
-
0037655074
-
Live bacteria as the basis for immunotherapies against cancer
-
Chabalgoity JA, Dougan G, Mastroeni P, Aspinall RJ. Live bacteria as the basis for immunotherapies against cancer. Expert. Rev. J. Clin. Invests. 1, 495-505 (2002).
-
(2002)
Expert. Rev. J. Clin. Invests.
, vol.1
, pp. 495-505
-
-
Chabalgoity, J.A.1
Dougan, G.2
Mastroeni, P.3
Aspinall, R.J.4
-
95
-
-
5144233489
-
Gene-based vaccines and immunotherapeutics
-
Liu M, Acres B, Balloul JM et al. Gene-based vaccines and immunotherapeutics. Proc. Natl Acad. Sci. USA 101(Suppl. 2), 14567-14571 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.SUPPL. 2
, pp. 14567-14571
-
-
Liu, M.1
Acres, B.2
Balloul, J.M.3
-
96
-
-
0034666228
-
Development of non-live vectors and procedures (liposomes, pseudoviral particles, toxin, beads, adjuvantsellipsis) as tools for cancer vaccines
-
Tartour E, Ciree A, Haicheur N, Benchetrit F, Fridman WH. Development of non-live vectors and procedures (liposomes, pseudoviral particles, toxin, beads, adjuvantsellipsis) as tools for cancer vaccines. Immunol. Lett. 74, 45-50 (2000).
-
(2000)
Immunol. Lett.
, vol.74
, pp. 45-50
-
-
Tartour, E.1
Ciree, A.2
Haicheur, N.3
Benchetrit, F.4
Fridman, W.H.5
-
97
-
-
9244257843
-
Virus-like particles as vaccines and vessels for the delivery of small molecules
-
Garcea RL, Gissmann L. Virus-like particles as vaccines and vessels for the delivery of small molecules. Curr. Opin. Biotechnol. 15, 513-517 (2004).
-
(2004)
Curr. Opin. Biotechnol.
, vol.15
, pp. 513-517
-
-
Garcea, R.L.1
Gissmann, L.2
-
98
-
-
16644365093
-
Exploiting dendritic cells for active immunotherapy of cancer and chronic infection
-
O'Neill D, Bhardwaj N. Exploiting dendritic cells for active immunotherapy of cancer and chronic infection. Methods Mol. Med. 109, 1-18 (2005).
-
(2005)
Methods Mol. Med.
, vol.109
, pp. 1-18
-
-
O'Neill, D.1
Bhardwaj, N.2
-
100
-
-
0037744913
-
Kunjin virus replicon vectors for human immunodeficiency virus vaccine development
-
Harvey TJ, Anraku I, Linedale R et al. Kunjin virus replicon vectors for human immunodeficiency virus vaccine development. J. Virol. 77, 7796-7803 (2003).
-
(2003)
J. Virol.
, vol.77
, pp. 7796-7803
-
-
Harvey, T.J.1
Anraku, I.2
Linedale, R.3
-
101
-
-
0036157469
-
Prime-boost immunization generates a high frequency, high-avidity CD8(+) cytotoxic T-lymphocyte population
-
Estcourt MJ, Ramsay AJ, Brooks A et al. Prime-boost immunization generates a high frequency, high-avidity CD8(+) cytotoxic T-lymphocyte population. Int. Immunol. 14, 31-37 (2002).
-
(2002)
Int. Immunol.
, vol.14
, pp. 31-37
-
-
Estcourt, M.J.1
Ramsay, A.J.2
Brooks, A.3
-
102
-
-
0037371476
-
Prime boost vaccination strategies: CD8 T-cell numbers, protection, and Th1 bias
-
Woodberry T, Gardner J, Elliott SL et al. Prime boost vaccination strategies: CD8 T-cell numbers, protection, and Th1 bias. J. Immunol. 170, 2599-2604 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 2599-2604
-
-
Woodberry, T.1
Gardner, J.2
Elliott, S.L.3
-
103
-
-
0025287307
-
Antiviral cytotoxic T-cell response induced by in vivo priming with a free synthetic peptide
-
Aichele P, Hengartner H, Zinkernagel RM, Schulz M. Antiviral cytotoxic T-cell response induced by in vivo priming with a free synthetic peptide. J. Exp. Med. 171, 1815-1820 (1990).
-
(1990)
J. Exp. Med.
, vol.171
, pp. 1815-1820
-
-
Aichele, P.1
Hengartner, H.2
Zinkernagel, R.M.3
Schulz, M.4
-
104
-
-
0034797737
-
Identification of canine helper T-cell epitopes from the fusion protein of canine distemper virus
-
Ghosh S, Walker J, Jackson DC. Identification of canine helper T-cell epitopes from the fusion protein of canine distemper virus. Immunology 104, 58-66 (2001).
-
(2001)
Immunology
, vol.104
, pp. 58-66
-
-
Ghosh, S.1
Walker, J.2
Jackson, D.C.3
-
105
-
-
15844428018
-
+ T-cell immunity against the human papillomavirus-18 E6 transforming protein in healthy donors: Identification of promiscuous naturally processed epitopes
-
+ T-cell immunity against the human papillomavirus-18 E6 transforming protein in healthy donors: identification of promiscuous naturally processed epitopes. Eur. J. Immunol. 35, 806-815 (2005).
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 806-815
-
-
Facchinetti, V.1
Seresini, S.2
Longhi, R.3
-
106
-
-
7044254970
-
Identification of an HLA-DR-restricted peptide epitope with a promiscuous binding pattern derived from the cancer testis antigen HOM-MEL-40/SSX2
-
Neumann F, Wagner C, Stevanovic S et al. Identification of an HLA-DR-restricted peptide epitope with a promiscuous binding pattern derived from the cancer testis antigen HOM-MEL-40/SSX2. Int. J. Cancer 112, 661-668 (2004).
-
(2004)
Int. J. Cancer
, vol.112
, pp. 661-668
-
-
Neumann, F.1
Wagner, C.2
Stevanovic, S.3
-
107
-
-
7444271904
-
A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T-cell responses
-
Jackson DC, Lau YF, Le T et al. A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T-cell responses. Proc. Natl Acad. Sci. USA 101, 15440-15445 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 15440-15445
-
-
Jackson, D.C.1
Lau, Y.F.2
Le, T.3
-
108
-
-
0038515116
-
Polytope vaccines for the codelivery of multiple CD8 T-cell epitopes
-
Suhrbier A. Polytope vaccines for the codelivery of multiple CD8 T-cell epitopes. Expert. Rev. J. Clin. Invests. 1, 207-213 (2002).
-
(2002)
Expert. Rev. J. Clin. Invests.
, vol.1
, pp. 207-213
-
-
Suhrbier, A.1
-
109
-
-
3342994925
-
Long-term multiepitopic cytotoxic-T-lymphocyte responses induced in chimpanzees by combinations of Plasmodium falciparum liver-stage peptides and lipopeptides
-
BenMohamed L, Thomas A, Druilhe P. Long-term multiepitopic cytotoxic-T-lymphocyte responses induced in chimpanzees by combinations of Plasmodium falciparum liver-stage peptides and lipopeptides. Infect. Immun. 72, 4376-4384 (2004).
-
(2004)
Infect. Immun.
, vol.72
, pp. 4376-4384
-
-
BenMohamed, L.1
Thomas, A.2
Druilhe, P.3
-
110
-
-
24644458684
-
Lipid-based self-adjuvanting vaccines
-
Brown LE, Jackson DC. Lipid-based self-adjuvanting vaccines. Curr. Drug Delivery (2005). Focuses on the use of lipopeptides as immunogens to induce antibody and cytotoxic T-lymphocyte responses. The authors discuss key issues that can affect the immunogenicity of lipopeptides, such as the nature of the lipid, spatial distribution of epitopes and incorporation of T-helper epitopes. Mechanisms of action and their potential clinical applications of lipopeptides are extensively discussed.
-
(2005)
Curr. Drug Delivery
-
-
Brown, L.E.1
Jackson, D.C.2
-
111
-
-
0034997003
-
Defined synthetic vaccines
-
Zauner W, Lingnau K, Mattner F, von Gabain A, Buschle M. Defined synthetic vaccines. Biol. Chem. 382, 581-595 (2001).
-
(2001)
Biol. Chem.
, vol.382
, pp. 581-595
-
-
Zauner, W.1
Lingnau, K.2
Mattner, F.3
Von Gabain, A.4
Buschle, M.5
-
112
-
-
0024389666
-
In vivo priming of virus-specific cytotoxic T-lymphocytes with synthetic lipopeptide vaccine
-
Deres K, Schild H, Wiesmuller KH, Jung G, Rammensee HG. In vivo priming of virus-specific cytotoxic T-lymphocytes with synthetic lipopeptide vaccine. Nature 342, 561-564 (1989).
-
(1989)
Nature
, vol.342
, pp. 561-564
-
-
Deres, K.1
Schild, H.2
Wiesmuller, K.H.3
Jung, G.4
Rammensee, H.G.5
-
113
-
-
0026091287
-
Efficiency of peptides and lipopeptides for in vivo priming of virus-specific cytotoxic T-cells
-
Schild H, Deres K, Wiesmuller KH, Jung G, Rammensee HG. Efficiency of peptides and lipopeptides for in vivo priming of virus-specific cytotoxic T-cells. Eur. J. Immunol. 21, 2649-2654 (1991).
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2649-2654
-
-
Schild, H.1
Deres, K.2
Wiesmuller, K.H.3
Jung, G.4
Rammensee, H.G.5
-
114
-
-
0036839103
-
Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines
-
Zeng W, Ghosh S, Lau YF, Brown LE, Jackson DC. Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines. J. Immunol. 169, 4905-4912 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 4905-4912
-
-
Zeng, W.1
Ghosh, S.2
Lau, Y.F.3
Brown, L.E.4
Jackson, D.C.5
-
115
-
-
0037449492
-
Response of ELA-Al horses immunized with lipopeptide containing an equine infectious anemia virus ELA-A1-restricted CTL epitope to virus challenge
-
Ridgely SL, Zhang B, McGuire TC. Response of ELA-Al horses immunized with lipopeptide containing an equine infectious anemia virus ELA-A1-restricted CTL epitope to virus challenge. J. Clin. Invest. 21, 491-506 (2003).
-
(2003)
J. Clin. Invest.
, vol.21
, pp. 491-506
-
-
Ridgely, S.L.1
Zhang, B.2
McGuire, T.C.3
-
116
-
-
0036295173
-
Lipopeptide vaccines - Yesterday, today, and tomorrow
-
BenMohamed L, Wechsler SL, Nesburn AB. Lipopeptide vaccines - yesterday, today, and tomorrow. Lancet Infect. Dis. 2, 425-431 (2002).
-
(2002)
Lancet Infect. Dis.
, vol.2
, pp. 425-431
-
-
BenMohamed, L.1
Wechsler, S.L.2
Nesburn, A.B.3
-
117
-
-
0033990731
-
Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens
-
Zeng W, Jackson DC, Murray J, Rose K, Brown LE. Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens. J. Clin. Invest. 18, 1031-1039 (2000).
-
(2000)
J. Clin. Invest.
, vol.18
, pp. 1031-1039
-
-
Zeng, W.1
Jackson, D.C.2
Murray, J.3
Rose, K.4
Brown, L.E.5
-
118
-
-
0036229655
-
Induction of long-term memory CD8(+) T-cells for recall of viral clearing responses against influenza virus
-
Deliyannis G, Jackson DC, Ede NJ et al. Induction of long-term memory CD8(+) T-cells for recall of viral clearing responses against influenza virus. J. Virol. 76, 4212-4221 (2002).
-
(2002)
J. Virol.
, vol.76
, pp. 4212-4221
-
-
Deliyannis, G.1
Jackson, D.C.2
Ede, N.J.3
-
119
-
-
0035898952
-
Assembly of synthetic peptide vaccines by chemoselective ligation of epitopes: Influence of different chemical linkages and epitope orientations on biological activity
-
Zeng W, Ghosh S, Macris M, Pagnon J, Jackson DC. Assembly of synthetic peptide vaccines by chemoselective ligation of epitopes: influence of different chemical linkages and epitope orientations on biological activity. J. Clin. Invest. 19, 3843-3852 (2001).
-
(2001)
J. Clin. Invest.
, vol.19
, pp. 3843-3852
-
-
Zeng, W.1
Ghosh, S.2
Macris, M.3
Pagnon, J.4
Jackson, D.C.5
-
120
-
-
0034085898
-
The geometry of synthetic peptide-based immunogens affects the efficiency of T-cell stimulation by professional antigen-presenting cells
-
Fitzmaurice CJ, Brown LE, Kronin V, Jackson DC. The geometry of synthetic peptide-based immunogens affects the efficiency of T-cell stimulation by professional antigen-presenting cells. Int. Immunol. 12, 527-535 (2000).
-
(2000)
Int. Immunol.
, vol.12
, pp. 527-535
-
-
Fitzmaurice, C.J.1
Brown, L.E.2
Kronin, V.3
Jackson, D.C.4
-
121
-
-
0033605091
-
Lipopeptide particles as the immunologically active component of CTL inducing vaccines
-
Tsunoda I, Sette A, Fujinami RS et al. Lipopeptide particles as the immunologically active component of CTL inducing vaccines. J. Clin. Invest. 17, 675-685 (1999).
-
(1999)
J. Clin. Invest.
, vol.17
, pp. 675-685
-
-
Tsunoda, I.1
Sette, A.2
Fujinami, R.S.3
-
122
-
-
0037329141
-
Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus
-
Chua BY, Healy A, Cameron PU et al. Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus. Immunol. Cell Biol. 81, 67-72 (2003).
-
(2003)
Immunol. Cell Biol.
, vol.81
, pp. 67-72
-
-
Chua, B.Y.1
Healy, A.2
Cameron, P.U.3
-
123
-
-
0035500587
-
Lipopeptide presentation pathway in dendritic cells
-
Hosmalin A, Andrieu M, Loing E et al. Lipopeptide presentation pathway in dendritic cells. Immunol. Lett. 79, 97-100 (2001).
-
(2001)
Immunol. Lett.
, vol.79
, pp. 97-100
-
-
Hosmalin, A.1
Andrieu, M.2
Loing, E.3
|