-
1
-
-
0021859627
-
A novel serine protease expressed by cytotoxic T lymphocytes
-
Pasternack M.S., Eisen H.N. A novel serine protease expressed by cytotoxic T lymphocytes. Nature. 314:1985;743-745.
-
(1985)
Nature
, vol.314
, pp. 743-745
-
-
Pasternack, M.S.1
Eisen, H.N.2
-
2
-
-
0022624829
-
Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte
-
Gershenfeld H.K., Weissman I.L. Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte. Science. 232:1986;854.
-
(1986)
Science
, vol.232
, pp. 854
-
-
Gershenfeld, H.K.1
Weissman, I.L.2
-
3
-
-
0023927292
-
Appearance of granule-associated molecules during activation of cytolytic T-lymphocyte precursors by defined stimuli
-
Garcia-Sanz J.A., Velotti F., MacDonald H.R., Masson D., Tschopp J., Nabholz M. Appearance of granule-associated molecules during activation of cytolytic T-lymphocyte precursors by defined stimuli. Immunology. 64:1988;129-134.
-
(1988)
Immunology
, vol.64
, pp. 129-134
-
-
Garcia-Sanz, J.A.1
Velotti, F.2
MacDonald, H.R.3
Masson, D.4
Tschopp, J.5
Nabholz, M.6
-
4
-
-
0025169597
-
Cell specificity of granzyme gene expression
-
Garcia-Sanz J.A., MacDonald H.R., Jenne D.E., Tschopp J., Nabholz M. Cell specificity of granzyme gene expression. J Immunol. 145:1990;3111-3118.
-
(1990)
J Immunol
, vol.145
, pp. 3111-3118
-
-
Garcia-Sanz, J.A.1
MacDonald, H.R.2
Jenne, D.E.3
Tschopp, J.4
Nabholz, M.5
-
5
-
-
0141741403
-
Lytic granules, secretory lysosomes and disease
-
Clark R, Griffiths GM: Lytic granules, secretory lysosomes and disease. Curr Opin Immunol 2003, 15: this issue.
-
(2003)
Curr Opin Immunol
, Issue.THIS ISSUE
, pp. 15
-
-
Clark, R.1
Griffiths, G.M.2
-
6
-
-
0035412370
-
CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection
-
Chen G., Shankar P., Lange C., Valdez H., Skolnik P.R., Wu L., Manjunath N., Lieberman J. CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection. Blood. 98:2001;156-164.
-
(2001)
Blood
, vol.98
, pp. 156-164
-
-
Chen, G.1
Shankar, P.2
Lange, C.3
Valdez, H.4
Skolnik, P.R.5
Wu, L.6
Manjunath, N.7
Lieberman, J.8
-
7
-
-
0037221406
-
Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic
-
Zhang D., Shankar P., Xu Z., Harnisch B., Chen G., Lange C., Lee S.J., Valdez H., Lederman M.M., Lieberman J. Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic. Blood. 101:2003;226-235.
-
(2003)
Blood
, vol.101
, pp. 226-235
-
-
Zhang, D.1
Shankar, P.2
Xu, Z.3
Harnisch, B.4
Chen, G.5
Lange, C.6
Lee, S.J.7
Valdez, H.8
Lederman, M.M.9
Lieberman, J.10
-
8
-
-
0026474805
-
Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions
-
Shi L., Kam C.M., Powers J.C., Aebersold R., Greenberg A.H. Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. J Exp Med. 176:1992;1521-1529.
-
(1992)
J Exp Med
, vol.176
, pp. 1521-1529
-
-
Shi, L.1
Kam, C.M.2
Powers, J.C.3
Aebersold, R.4
Greenberg, A.H.5
-
9
-
-
0026532606
-
A natural killer cell granule protein that induces DNA fragmentation and apoptosis
-
Shi L., Kraut R.P., Aebersold R., Greenberg A.H. A natural killer cell granule protein that induces DNA fragmentation and apoptosis. J Exp Med. 175:1992;553-566.
-
(1992)
J Exp Med
, vol.175
, pp. 553-566
-
-
Shi, L.1
Kraut, R.P.2
Aebersold, R.3
Greenberg, A.H.4
-
10
-
-
0036312429
-
The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells
-
Pardo J., Balkow S., Anel A., Simon M.M. The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells. Eur J Immunol. 32:2002;1980-1985.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1980-1985
-
-
Pardo, J.1
Balkow, S.2
Anel, A.3
Simon, M.M.4
-
11
-
-
0033137079
-
Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation
-
Beresford P.J., Xia Z., Greenberg A.H., Lieberman J. Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation. Immunity. 10:1999;585-594.
-
(1999)
Immunity
, vol.10
, pp. 585-594
-
-
Beresford, P.J.1
Xia, Z.2
Greenberg, A.H.3
Lieberman, J.4
-
12
-
-
0033136315
-
Granzyme A initiates an alternative pathway for granule-mediated apoptosis
-
Shresta S., Graubert T.A., Thomas D.A., Raptis S.Z., Ley T.J. Granzyme A initiates an alternative pathway for granule-mediated apoptosis. Immunity. 10:1999;595-605.
-
(1999)
Immunity
, vol.10
, pp. 595-605
-
-
Shresta, S.1
Graubert, T.A.2
Thomas, D.A.3
Raptis, S.Z.4
Ley, T.J.5
-
13
-
-
0037318699
-
Granzyme A: The road less traveled
-
Pinkoski M.J., Green D.R. Granzyme A: the road less traveled. Nat Immunol. 4:2003;106-108.
-
(2003)
Nat Immunol
, vol.4
, pp. 106-108
-
-
Pinkoski, M.J.1
Green, D.R.2
-
14
-
-
0028988261
-
Granzyme A is an interleukin 1 beta-converting enzyme
-
Irmler M., Hertig S., MacDonald H.R., Sadoul R., Becherer J.D., Proudfoot A., Solari R., Tschopp J. Granzyme A is an interleukin 1 beta-converting enzyme. J Exp Med. 181:1995;1917-1922.
-
(1995)
J Exp Med
, vol.181
, pp. 1917-1922
-
-
Irmler, M.1
Hertig, S.2
MacDonald, H.R.3
Sadoul, R.4
Becherer, J.D.5
Proudfoot, A.6
Solari, R.7
Tschopp, J.8
-
15
-
-
0029963625
-
Extracellular activities of human granzyme A. Monocyte activation by granzyme A versus alpha-thrombin
-
Sower L.E., Froelich C.J., Allegretto N., Rose P.M., Hanna W.D., Klimpel G.R. Extracellular activities of human granzyme A. Monocyte activation by granzyme A versus alpha-thrombin. J Immunol. 156:1996;2585-2590.
-
(1996)
J Immunol
, vol.156
, pp. 2585-2590
-
-
Sower, L.E.1
Froelich, C.J.2
Allegretto, N.3
Rose, P.M.4
Hanna, W.D.5
Klimpel, G.R.6
-
16
-
-
0030578437
-
Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines
-
Sower L.E., Klimpel G.R., Hanna W., Froelich C.J. Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines. Cell Immunol. 171:1996;159-163.
-
(1996)
Cell Immunol
, vol.171
, pp. 159-163
-
-
Sower, L.E.1
Klimpel, G.R.2
Hanna, W.3
Froelich, C.J.4
-
17
-
-
0029871382
-
The serine protease granzyme A does not induce platelet aggregation but inhibits responses triggered by thrombin
-
Suidan H.S., Clemetson K.J., Brown-Luedi M., Niclou S.P., Clemetson J.M., Tschopp J., Monard D. The serine protease granzyme A does not induce platelet aggregation but inhibits responses triggered by thrombin. Biochem J. 315:1996;939-945.
-
(1996)
Biochem J
, vol.315
, pp. 939-945
-
-
Suidan, H.S.1
Clemetson, K.J.2
Brown-Luedi, M.3
Niclou, S.P.4
Clemetson, J.M.5
Tschopp, J.6
Monard, D.7
-
18
-
-
0028967988
-
Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin
-
Nakajima H., Park H.L., Henkart P.A. Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin. J Exp Med. 181:1995;1037-1046.
-
(1995)
J Exp Med
, vol.181
, pp. 1037-1046
-
-
Nakajima, H.1
Park, H.L.2
Henkart, P.A.3
-
19
-
-
0030044052
-
Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis
-
Trapani J.A., Browne K.A., Smyth M.J., Jans D.A. Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis. J Biol Chem. 271:1996;4127-4133.
-
(1996)
J Biol Chem
, vol.271
, pp. 4127-4133
-
-
Trapani, J.A.1
Browne, K.A.2
Smyth, M.J.3
Jans, D.A.4
-
20
-
-
0031669558
-
Nuclear targeting of the serine protease granzyme A (fragmentin-1)
-
Jans D.A., Briggs L.J., Jans P., Froelich C.J., Parasivam G., Kumar S., Sutton V.R., Trapani J.A. Nuclear targeting of the serine protease granzyme A (fragmentin-1). J Cell Sci. 111:1998;2645-2654.
-
(1998)
J Cell Sci
, vol.111
, pp. 2645-2654
-
-
Jans, D.A.1
Briggs, L.J.2
Jans, P.3
Froelich, C.J.4
Parasivam, G.5
Kumar, S.6
Sutton, V.R.7
Trapani, J.A.8
-
21
-
-
0026353348
-
Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro
-
Pasternack M.S., Bleier K.J., McInerney T.N. Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro. J Biol Chem. 266:1991;14703-14708.
-
(1991)
J Biol Chem
, vol.266
, pp. 14703-14708
-
-
Pasternack, M.S.1
Bleier, K.J.2
McInerney, T.N.3
-
22
-
-
0035900714
-
Granzyme A activates an endoplasmic reticulum-associated caspase- independent nuclease to induce single-stranded DNA nicks
-
Beresford P.J., Zhang D., Oh D.Y., Fan Z., Greer E.L., Russo M.L., Jaju M., Lieberman J. Granzyme A activates an endoplasmic reticulum-associated caspase- independent nuclease to induce single-stranded DNA nicks. J Biol Chem. 276:2001;43285-43293.
-
(2001)
J Biol Chem
, vol.276
, pp. 43285-43293
-
-
Beresford, P.J.1
Zhang, D.2
Oh, D.Y.3
Fan, Z.4
Greer, E.L.5
Russo, M.L.6
Jaju, M.7
Lieberman, J.8
-
23
-
-
0028258577
-
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
-
Heusel J.W., Wesselschmidt R.L., Shresta S., Russell J.H., Ley T.J. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell. 76:1994;977-987.
-
(1994)
Cell
, vol.76
, pp. 977-987
-
-
Heusel, J.W.1
Wesselschmidt, R.L.2
Shresta, S.3
Russell, J.H.4
Ley, T.J.5
-
24
-
-
0030014911
-
Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia
-
Mullbacher A., Ebnet K., Blanden R.V., Hla R.T., Stehle T., Museteanu C., Simon M.M. Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia. Proc Natl Acad Sci USA. 93:1996;5783-5787.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5783-5787
-
-
Mullbacher, A.1
Ebnet, K.2
Blanden, R.V.3
Hla, R.T.4
Stehle, T.5
Museteanu, C.6
Simon, M.M.7
-
25
-
-
0033598718
-
Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
-
Mullbacher A., Waring P., Tha Hla R., Tran T., Chin S., Stehle T., Museteanu C., Simon M.M. Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes. Proc Natl Acad Sci USA. 96:1999;13950-13955.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13950-13955
-
-
Mullbacher, A.1
Waring, P.2
Tha Hla, R.3
Tran, T.4
Chin, S.5
Stehle, T.6
Museteanu, C.7
Simon, M.M.8
-
26
-
-
0033986159
-
Granzyme A, a noncytolytic component of CD8(+) cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice
-
Pereira R.A., Simon M.M., Simmons A. Granzyme A, a noncytolytic component of CD8(+) cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice. J Virol. 74:2000;1029-1032.
-
(2000)
J Virol
, vol.74
, pp. 1029-1032
-
-
Pereira, R.A.1
Simon, M.M.2
Simmons, A.3
-
27
-
-
0035863798
-
The restricted expression of granzyme M in human lymphocytes
-
Sayers T.J., Brooks A.D., Ward J.M., Hoshino T., Bere W.E., Wiegand G.W., Kelley J.M., Smyth M.J. The restricted expression of granzyme M in human lymphocytes. J Immunol. 166:2001;765-771.
-
(2001)
J Immunol
, vol.166
, pp. 765-771
-
-
Sayers, T.J.1
Brooks, A.D.2
Ward, J.M.3
Hoshino, T.4
Bere, W.E.5
Wiegand, G.W.6
Kelley, J.M.7
Smyth, M.J.8
-
28
-
-
0029914132
-
A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes
-
Sun J., Bird C.H., Sutton V., McDonald L., Coughlin P.B., DeJong T.A., Trapani J.A., Bird P.I. A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes. J Biol Chem. 271:1996;27802-27809.
-
(1996)
J Biol Chem
, vol.271
, pp. 27802-27809
-
-
Sun, J.1
Bird, C.H.2
Sutton, V.3
McDonald, L.4
Coughlin, P.B.5
DeJong, T.A.6
Trapani, J.A.7
Bird, P.I.8
-
29
-
-
0031008162
-
A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9)
-
Sun J., Ooms L., Bird C.H., Sutton V.R., Trapani J.A., Bird P.I. A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9). J Biol Chem. 272:1997;15434-15441.
-
(1997)
J Biol Chem
, vol.272
, pp. 15434-15441
-
-
Sun, J.1
Ooms, L.2
Bird, C.H.3
Sutton, V.R.4
Trapani, J.A.5
Bird, P.I.6
-
30
-
-
0037687435
-
Purification and identification of a binding protein for pancreatic secretory trypsin inhibitor: A novel role of the inhibitor as an anti-granzyme A
-
The authors describe the first identification of a naturally occurring inhibitor of GzmA.
-
Tsuzuki S., Kokado Y., Satomi S., Yamasaki Y., Hirayasu H., Iwanaga T., Fushiki T. Purification and identification of a binding protein for pancreatic secretory trypsin inhibitor: a novel role of the inhibitor as an anti-granzyme A. Biochem J. 372:2003;227-233 The authors describe the first identification of a naturally occurring inhibitor of GzmA.
-
(2003)
Biochem J
, vol.372
, pp. 227-233
-
-
Tsuzuki, S.1
Kokado, Y.2
Satomi, S.3
Yamasaki, Y.4
Hirayasu, H.5
Iwanaga, T.6
Fushiki, T.7
-
31
-
-
0034651593
-
Extracellular granzyme A, complexed to proteoglycans, is protected against inactivation by protease inhibitors
-
Spaeny-Dekking E.H., Kamp A.M., Froelich C.J., Hack C.E. Extracellular granzyme A, complexed to proteoglycans, is protected against inactivation by protease inhibitors. Blood. 95:2000;1465-1472.
-
(2000)
Blood
, vol.95
, pp. 1465-1472
-
-
Spaeny-Dekking, E.H.1
Kamp, A.M.2
Froelich, C.J.3
Hack, C.E.4
-
32
-
-
0032055984
-
Extracellular granzymes A and B in humans: Detection of native species during CTL responses in vitro and in vivo
-
Spaeny-Dekking E.H., Hanna W.L., Wolbink A.M., Wever P.C., Kummer A.J., Swaak A.J., Middeldorp J.M., Huisman H.G., Froelich C.J., Hack C.E. Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo. J Immunol. 160:1998;3610-3616.
-
(1998)
J Immunol
, vol.160
, pp. 3610-3616
-
-
Spaeny-Dekking, E.H.1
Hanna, W.L.2
Wolbink, A.M.3
Wever, P.C.4
Kummer, A.J.5
Swaak, A.J.6
Middeldorp, J.M.7
Huisman, H.G.8
Froelich, C.J.9
Hack, C.E.10
-
33
-
-
0035826778
-
Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis
-
Zhang D., Beresford P.J., Greenberg A.H., Lieberman J. Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis. Proc Natl Acad Sci USA. 98:2001;5746-5751.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5746-5751
-
-
Zhang, D.1
Beresford, P.J.2
Greenberg, A.H.3
Lieberman, J.4
-
34
-
-
0037318731
-
Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A
-
The authors show that Ape1 is part of the SET complex; GzmA cleavage of Ape1 prevents the cell from repairing damage and recovering.
-
Fan Z., Beresford P.J., Zhang D., Xu Z., Novina C.D., Yoshida A., Pommier Y., Lieberman J. Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A. Nat Immunol. 4:2003;145-153 The authors show that Ape1 is part of the SET complex; GzmA cleavage of Ape1 prevents the cell from repairing damage and recovering.
-
(2003)
Nat Immunol
, vol.4
, pp. 145-153
-
-
Fan, Z.1
Beresford, P.J.2
Zhang, D.3
Xu, Z.4
Novina, C.D.5
Yoshida, A.6
Pommier, Y.7
Lieberman, J.8
-
35
-
-
0037423932
-
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
-
This paper identifies NM23-H1 as the GzmA-activated DNase and provides the first description of a caspase-independent mechanism of apoptotic DNA damage.
-
Fan Z., Beresford P.J., Oh D.Y., Zhang D., Lieberman J. Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell. 112:2003;659-672 This paper identifies NM23-H1 as the GzmA-activated DNase and provides the first description of a caspase-independent mechanism of apoptotic DNA damage.
-
(2003)
Cell
, vol.112
, pp. 659-672
-
-
Fan, Z.1
Beresford, P.J.2
Oh, D.Y.3
Zhang, D.4
Lieberman, J.5
-
36
-
-
0030787867
-
Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them
-
Beresford P.J., Kam C.M., Powers J.C., Lieberman J. Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them. Proc Natl Acad Sci USA. 94:1997;9285-9290.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9285-9290
-
-
Beresford, P.J.1
Kam, C.M.2
Powers, J.C.3
Lieberman, J.4
-
37
-
-
0036199666
-
HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A
-
Fan Z., Beresford P.J., Zhang D., Lieberman J. HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A. Mol Cell Biol. 22:2002;2810-2820.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2810-2820
-
-
Fan, Z.1
Beresford, P.J.2
Zhang, D.3
Lieberman, J.4
-
38
-
-
0034597057
-
Protein ligands to HuR modulate its interaction with target mRNAs in vivo
-
Brennan C.M., Gallouzi I.E., Steitz J.A. Protein ligands to HuR modulate its interaction with target mRNAs in vivo. J Cell Biol. 151:2000;1-14.
-
(2000)
J Cell Biol
, vol.151
, pp. 1-14
-
-
Brennan, C.M.1
Gallouzi, I.E.2
Steitz, J.A.3
-
39
-
-
0034462693
-
Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators
-
Shikama N., Chan H.M., Krstic-Demonacos M., Smith L., Lee C.W., Cairns W., La Thangue N.B. Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators. Mol Cell Biol. 20:2000;8933-8943.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8933-8943
-
-
Shikama, N.1
Chan, H.M.2
Krstic-Demonacos, M.3
Smith, L.4
Lee, C.W.5
Cairns, W.6
La Thangue, N.B.7
-
40
-
-
0034850959
-
Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock
-
Gallouzi I.E., Brennan C.M., Steitz J.A. Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock. RNA. 7:2001;1348-1361.
-
(2001)
RNA
, vol.7
, pp. 1348-1361
-
-
Gallouzi, I.E.1
Brennan, C.M.2
Steitz, J.A.3
-
41
-
-
0035846894
-
Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein
-
Seo S., McNamara P., Heo S., Turner A., Lane W.S., Chakravarti D. Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. Cell. 104:2001;119-130.
-
(2001)
Cell
, vol.104
, pp. 119-130
-
-
Seo, S.1
McNamara, P.2
Heo, S.3
Turner, A.4
Lane, W.S.5
Chakravarti, D.6
-
42
-
-
0037134538
-
Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex
-
Seo S.B., Macfarlan T., McNamara P., Hong R., Mukai Y., Heo S., Chakravarti D. Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex. J Biol Chem. 277:2002;14005-14010.
-
(2002)
J Biol Chem
, vol.277
, pp. 14005-14010
-
-
Seo, S.B.1
Macfarlan, T.2
McNamara, P.3
Hong, R.4
Mukai, Y.5
Heo, S.6
Chakravarti, D.7
-
43
-
-
0037067661
-
The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing
-
Cervoni N., Detich N., Seo S.B., Chakravarti D., Szyf M. The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing. J Biol Chem. 277:2002;25026-25031.
-
(2002)
J Biol Chem
, vol.277
, pp. 25026-25031
-
-
Cervoni, N.1
Detich, N.2
Seo, S.B.3
Chakravarti, D.4
Szyf, M.5
-
44
-
-
0037423949
-
SET-ting the stage for life and death
-
Chakravarti D., Hong R. SET-ting the stage for life and death. Cell. 112:2003;589-591.
-
(2003)
Cell
, vol.112
, pp. 589-591
-
-
Chakravarti, D.1
Hong, R.2
-
45
-
-
0037428217
-
Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway
-
This study implicates pp32 in activating the apoptosome in caspase-mediated cell death.
-
Jiang X., Kim H.E., Shu H., Zhao Y., Zhang H., Kofron J., Donnelly J., Burns D., Ng S.C., Rosenberg S.et al. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science. 299:2003;223-226 This study implicates pp32 in activating the apoptosome in caspase-mediated cell death.
-
(2003)
Science
, vol.299
, pp. 223-226
-
-
Jiang, X.1
Kim, H.E.2
Shu, H.3
Zhao, Y.4
Zhang, H.5
Kofron, J.6
Donnelly, J.7
Burns, D.8
Ng, S.C.9
Rosenberg, S.10
-
46
-
-
0034160089
-
An 'environment to nucleus' signaling system operates in B lymphocytes: Redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation
-
Tell G., Zecca A., Pellizzari L., Spessotto P., Colombatti A., Kelley M.R., Damante G., Pucillo C. An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation. Nucleic Acids Res. 28:2000;1099-1105.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 1099-1105
-
-
Tell, G.1
Zecca, A.2
Pellizzari, L.3
Spessotto, P.4
Colombatti, A.5
Kelley, M.R.6
Damante, G.7
Pucillo, C.8
-
47
-
-
0026323008
-
Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: Definition of a family of DNA repair enzymes
-
Demple B., Herman T., Chen D.S. Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes. Proc Natl Acad Sci USA. 88:1991;11450-11454.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11450-11454
-
-
Demple, B.1
Herman, T.2
Chen, D.S.3
-
48
-
-
0026714672
-
Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme
-
Xanthoudakis S., Miao G., Wang F., Pan Y.C., Curran T. Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J. 11:1992;3323-3335.
-
(1992)
EMBO J
, vol.11
, pp. 3323-3335
-
-
Xanthoudakis, S.1
Miao, G.2
Wang, F.3
Pan, Y.C.4
Curran, T.5
-
49
-
-
0026583944
-
Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity
-
Xanthoudakis S., Curran T. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J. 11:1992;653-665.
-
(1992)
EMBO J
, vol.11
, pp. 653-665
-
-
Xanthoudakis, S.1
Curran, T.2
-
51
-
-
0026693436
-
Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3′ half to different genes: Characterization of the set gene
-
von Lindern M., van Baal S., Wiegant J., Raap A., Hagemeijer A., Grosveld G. Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3′ half to different genes: characterization of the set gene. Mol Cell Biol. 12:1992;3346-3355.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3346-3355
-
-
Von Lindern, M.1
Van Baal, S.2
Wiegant, J.3
Raap, A.4
Hagemeijer, A.5
Grosveld, G.6
-
52
-
-
0029009403
-
Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis
-
Nagata K., Kawase H., Handa H., Yano K., Yamasaki M., Ishimi Y., Okuda A., Kikuchi A., Matsumoto K. Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis. Proc Natl Acad Sci USA. 92:1995;4279-4283.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4279-4283
-
-
Nagata, K.1
Kawase, H.2
Handa, H.3
Yano, K.4
Yamasaki, M.5
Ishimi, Y.6
Okuda, A.7
Kikuchi, A.8
Matsumoto, K.9
-
53
-
-
0032827034
-
Sperm chromatin decondensation by template activating factor I through direct interaction with basic proteins
-
Matsumoto K., Nagata K., Miyaji-Yamaguchi M., Kikuchi A., Tsujimoto M. Sperm chromatin decondensation by template activating factor I through direct interaction with basic proteins. Mol Cell Biol. 19:1999;6940-6952.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6940-6952
-
-
Matsumoto, K.1
Nagata, K.2
Miyaji-Yamaguchi, M.3
Kikuchi, A.4
Tsujimoto, M.5
-
54
-
-
0033407137
-
Histone- and chromatin-binding activity of template activating factor-I
-
Matsumoto K., Nagata K., Okuwaki M., Tsujimoto M. Histone- and chromatin-binding activity of template activating factor-I. FEBS Lett. 463:1999;285-288.
-
(1999)
FEBS Lett
, vol.463
, pp. 285-288
-
-
Matsumoto, K.1
Nagata, K.2
Okuwaki, M.3
Tsujimoto, M.4
-
55
-
-
0027263966
-
Template activating factor I, a novel host factor required to stimulate the adenovirus core DNA replication
-
Matsumoto K., Nagata K., Ui M., Hanaoka F. Template activating factor I, a novel host factor required to stimulate the adenovirus core DNA replication. J Biol Chem. 268:1993;10582-10587.
-
(1993)
J Biol Chem
, vol.268
, pp. 10582-10587
-
-
Matsumoto, K.1
Nagata, K.2
Ui, M.3
Hanaoka, F.4
-
56
-
-
0028898807
-
Stimulation of DNA transcription by the replication factor from the adenovirus genome in a chromatin-like structure
-
Matsumoto K., Okuwaki M., Kawase H., Handa H., Hanaoka F., Nagata K. Stimulation of DNA transcription by the replication factor from the adenovirus genome in a chromatin-like structure. J Biol Chem. 270:1995;9645-9650.
-
(1995)
J Biol Chem
, vol.270
, pp. 9645-9650
-
-
Matsumoto, K.1
Okuwaki, M.2
Kawase, H.3
Handa, H.4
Hanaoka, F.5
Nagata, K.6
-
57
-
-
0030723205
-
HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A
-
Adler H.T., Nallaseth F.S., Walter G., Tkachuk D.C. HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A. J Biol Chem. 272:1997;28407-28414.
-
(1997)
J Biol Chem
, vol.272
, pp. 28407-28414
-
-
Adler, H.T.1
Nallaseth, F.S.2
Walter, G.3
Tkachuk, D.C.4
-
58
-
-
0035912064
-
Tumor suppression and potentiation by manipulation of pp32 expression
-
Bai J., Brody J.R., Kadkol S.S., Pasternack G.R. Tumor suppression and potentiation by manipulation of pp32 expression. Oncogene. 20:2001;2153-2160.
-
(2001)
Oncogene
, vol.20
, pp. 2153-2160
-
-
Bai, J.1
Brody, J.R.2
Kadkol, S.S.3
Pasternack, G.R.4
-
59
-
-
0029665228
-
PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A
-
PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A. Biochemistry. 35:1996;6998-7002.
-
(1996)
Biochemistry
, vol.35
, pp. 6998-7002
-
-
Li, M.1
Makkinje, A.2
Damuni, Z.3
-
60
-
-
0029889342
-
The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A
-
Li M., Makkinje A., Damuni Z. The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A. J Biol Chem. 271:1996;11059-11062.
-
(1996)
J Biol Chem
, vol.271
, pp. 11059-11062
-
-
Li, M.1
Makkinje, A.2
Damuni, Z.3
-
61
-
-
0025103372
-
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A
-
Pallas D.C., Shahrik L.K., Martin B.L., Jaspers S., Miller T.B., Brautigan D.L., Roberts T.M. Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell. 60:1990;167-176.
-
(1990)
Cell
, vol.60
, pp. 167-176
-
-
Pallas, D.C.1
Shahrik, L.K.2
Martin, B.L.3
Jaspers, S.4
Miller, T.B.5
Brautigan, D.L.6
Roberts, T.M.7
-
62
-
-
0023937268
-
Evidence for a novel gene associated with low tumor metastatic potential
-
Steeg P.S., Bevilacqua G., Kopper L., Thorgeirsson U.P., Talmadge J.E., Liotta L.A., Sobel M.E. Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst. 80:1988;200-204.
-
(1988)
J Natl Cancer Inst
, vol.80
, pp. 200-204
-
-
Steeg, P.S.1
Bevilacqua, G.2
Kopper, L.3
Thorgeirsson, U.P.4
Talmadge, J.E.5
Liotta, L.A.6
Sobel, M.E.7
-
63
-
-
0037059740
-
NM23-H1 and NM23-H2 repress transcriptional activities of nuclease- hypersensitive elements in the platelet-derived growth factor-A promoter
-
Ma D., Xing Z., Liu B., Pedigo N.G., Zimmer S.G., Bai Z., Postel E.H., Kaetzel D.M. NM23-H1 and NM23-H2 repress transcriptional activities of nuclease- hypersensitive elements in the platelet-derived growth factor-A promoter. J Biol Chem. 277:2002;1560-1567.
-
(2002)
J Biol Chem
, vol.277
, pp. 1560-1567
-
-
Ma, D.1
Xing, Z.2
Liu, B.3
Pedigo, N.G.4
Zimmer, S.G.5
Bai, Z.6
Postel, E.H.7
Kaetzel, D.M.8
-
64
-
-
0033795962
-
Nm23/nucleoside diphosphate kinase in human cancers
-
Hartsough M.T., Steeg P.S. Nm23/nucleoside diphosphate kinase in human cancers. J Bioenerg Biomembr. 32:2000;301-308.
-
(2000)
J Bioenerg Biomembr
, vol.32
, pp. 301-308
-
-
Hartsough, M.T.1
Steeg, P.S.2
-
65
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
Liu X., Zou H., Slaughter C., Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell. 89:1997;175-184.
-
(1997)
Cell
, vol.89
, pp. 175-184
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
66
-
-
0031889132
-
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
-
Sakahira H., Enari M., Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature. 391:1998;96-99.
-
(1998)
Nature
, vol.391
, pp. 96-99
-
-
Sakahira, H.1
Enari, M.2
Nagata, S.3
-
67
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Enari M., Sakahira H., Yokohama H., Okawa K., Iwamatsu A., Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature. 391:1998;43-50.
-
(1998)
Nature
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokohama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
68
-
-
0033673428
-
DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis
-
Thomas D.A., Du C., Xu M., Wang X., Ley T.J. DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis. Immunity. 12:2000;621-632.
-
(2000)
Immunity
, vol.12
, pp. 621-632
-
-
Thomas, D.A.1
Du, C.2
Xu, M.3
Wang, X.4
Ley, T.J.5
-
69
-
-
17844365555
-
Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation
-
Sharif-Askari E., Alam A., Rheaume E., Beresford P.J., Scotto C., Sharma K., Lee D., DeWolf W.E., Nuttall M.E., Lieberman J.et al. Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation. EMBO J. 20:2001;3101-3113.
-
(2001)
EMBO J
, vol.20
, pp. 3101-3113
-
-
Sharif-Askari, E.1
Alam, A.2
Rheaume, E.3
Beresford, P.J.4
Scotto, C.5
Sharma, K.6
Lee, D.7
DeWolf, W.E.8
Nuttall, M.E.9
Lieberman, J.10
-
70
-
-
0031803216
-
A role for heat shock protein 27 in CTL-mediated cell death
-
Beresford P.J., Jaju M., Friedman R.S., Yoon M.J., Lieberman J. A role for heat shock protein 27 in CTL-mediated cell death. J Immunol. 161:1998;161-167.
-
(1998)
J Immunol
, vol.161
, pp. 161-167
-
-
Beresford, P.J.1
Jaju, M.2
Friedman, R.S.3
Yoon, M.J.4
Lieberman, J.5
-
71
-
-
0022648101
-
Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins
-
McKeon F.D., Kirschner M.W., Caput D. Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins. Nature. 319:1986;463-468.
-
(1986)
Nature
, vol.319
, pp. 463-468
-
-
McKeon, F.D.1
Kirschner, M.W.2
Caput, D.3
-
72
-
-
0025370462
-
In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase
-
Peter M., Nakagawa J., Doree M., Labbe J.C., Nigg E.A. In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell. 61:1990;591-602.
-
(1990)
Cell
, vol.61
, pp. 591-602
-
-
Peter, M.1
Nakagawa, J.2
Doree, M.3
Labbe, J.C.4
Nigg, E.A.5
-
73
-
-
0027989510
-
Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase
-
Oberhammer F.A., Hochegger K., Froschl G., Tiefenbacher R., Pavelka M. Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase. J Cell Biol. 126:1994;827-837.
-
(1994)
J Cell Biol
, vol.126
, pp. 827-837
-
-
Oberhammer, F.A.1
Hochegger, K.2
Froschl, G.3
Tiefenbacher, R.4
Pavelka, M.5
-
74
-
-
0030465544
-
Lamin proteolysis facilitates nuclear events during apoptosis
-
Rao L., Perez D., White E. Lamin proteolysis facilitates nuclear events during apoptosis. J Cell Biol. 135:1996;1441-1455.
-
(1996)
J Cell Biol
, vol.135
, pp. 1441-1455
-
-
Rao, L.1
Perez, D.2
White, E.3
-
75
-
-
0035793613
-
Induction of rapid histone degradation by the cytotoxic T lymphocyte protease granzyme A
-
Zhang D., Pasternack M.S., Beresford P.J., Wagner L., Greenberg A.H., Lieberman J. Induction of rapid histone degradation by the cytotoxic T lymphocyte protease granzyme A. J Biol Chem. 276:2001;3683-3690.
-
(2001)
J Biol Chem
, vol.276
, pp. 3683-3690
-
-
Zhang, D.1
Pasternack, M.S.2
Beresford, P.J.3
Wagner, L.4
Greenberg, A.H.5
Lieberman, J.6
-
76
-
-
0038730744
-
Crystal structure of the apoptosis-inducing human granzyme A dimer
-
Hink-Schauer C., Estebanez-Perpina E., Kurschus F.C., Bode W., Jenne D.E. Crystal structure of the apoptosis-inducing human granzyme A dimer. Nat Struct Biol. 10:2003;535-540.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 535-540
-
-
Hink-Schauer, C.1
Estebanez-Perpina, E.2
Kurschus, F.C.3
Bode, W.4
Jenne, D.E.5
-
77
-
-
0038392751
-
The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity
-
Bell J.K., Goetz D.H., Mahrus S., Harris J.L., Fletterick R.J., Craik C.S. The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity. Nat Struct Biol. 10:2003;527-534.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 527-534
-
-
Bell, J.K.1
Goetz, D.H.2
Mahrus, S.3
Harris, J.L.4
Fletterick, R.J.5
Craik, C.S.6
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