Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis

Cell Death and Differentiation

Volumn 12, Issue 10, 2005, Pages 1344-1357

  Fumarola, Claudia ^a   La Monica, S ^a   Alfieri, R R ^a   Borra, E ^a   Guidotti, G G ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Apoptosis; Cell size; Leucine; mTOR S6K pathway; Proliferation; Rapamycin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATE; APOPTOSIS INDUCING FACTOR; CASPASE; CASPASE 2; CYTOCHROME C; ENZYME PRECURSOR; ETOPOSIDE; FAS ANTIBODY; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GENE PRODUCT; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; MYC PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; RAPAMYCIN; RIBOSOME PROTEIN; S6 KINASE; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL PROTECTION; CELL SIZE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL GROWTH PROCESSES; CELL SIZE; CHROMONES; CYTOCHROME C GROUP; ENERGY METABOLISM; ENZYME INHIBITORS; HUMANS; JURKAT CELLS; LEUCINE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MORPHOLINES; PHOSPHORYLATION; PROTEIN KINASES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIROLIMUS;

MAMMALIA;

EID: 27144556646     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401660     Document Type: Article

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