-
1
-
-
0002470681
-
Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes
-
Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Hinnebusch, A. G. (2000) Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes. In: Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds.), pp. 185-243. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational Control of Gene Expression
, pp. 185-243
-
-
Hinnebusch, A.G.1
-
2
-
-
0031755020
-
Identification and characterization of pancreatic eukaryotic initiation factor 2 α-subunit kinase. PEK, involved in translational control
-
Shi, Y., Vattem, K. M., Sood, R., An, J., Liang, J., Stramm, L. & Wek, R. C. (1998) Identification and characterization of pancreatic eukaryotic initiation factor 2 α-subunit kinase, PEK, involved in translational control. Mol. Cell. Biol. 18: 7499-7509.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7499-7509
-
-
Shi, Y.1
Vattem, K.M.2
Sood, R.3
An, J.4
Liang, J.5
Stramm, L.6
Wek, R.C.7
-
3
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding, H. P., Zhang, Y. & Ron, D. (1999) Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397: 271-274.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
4
-
-
0032692634
-
Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: A new role for an old actor
-
Kaufman, R. J. (1999) Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor. Proc. Natl. Acad. Sci. U.S.A. 96: 11693-11695.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 11693-11695
-
-
Kaufman, R.J.1
-
5
-
-
0001657903
-
Heme-regulated elF2α kinase
-
Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Chen, J.-J. (2000) Heme-regulated elF2α kinase. In: Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds.), pp. 529-546. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational Control of Gene Expression
, pp. 529-546
-
-
Chen, J.-J.1
-
6
-
-
0001598487
-
Characterization of a mammalian homolog of GCN2 eukaryotic initiation factor 2α kinase
-
Berlanga, J. J., Santoyo, J. & de Haro, C. (1999) Characterization of a mammalian homolog of GCN2 eukaryotic initiation factor 2α kinase. Eur. J. Biochem. 265: 754-762.
-
(1999)
Eur. J. Biochem.
, vol.265
, pp. 754-762
-
-
Berlanga, J.J.1
Santoyo, J.2
De Haro, C.3
-
7
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding, H. P., Novoa, I., Zhang, Y., Zeng, H., Wek, R. C., Schapira, M. & Ron, D. (2000) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 6: 1099-1108.
-
(2000)
Mol. Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.C.5
Schapira, M.6
Ron, D.7
-
8
-
-
0033962298
-
A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2α
-
Sood, R., Porter, A. C., Olsen, D., Cavener, D. R. & Wek, R. C. (2000) A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2α. Genetics 154: 787-801.
-
(2000)
Genetics
, vol.154
, pp. 787-801
-
-
Sood, R.1
Porter, A.C.2
Olsen, D.3
Cavener, D.R.4
Wek, R.C.5
-
9
-
-
0034973590
-
Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast
-
Natarajan, K., Meyer, M. R., Jackson, B. M., Slade, D., Roberts, C., Hinnebusch, A. G. & Marton, M. J. (2001) Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol. Cell. Biol. 21: 4347-4368.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4347-4368
-
-
Natarajan, K.1
Meyer, M.R.2
Jackson, B.M.3
Slade, D.4
Roberts, C.5
Hinnebusch, A.G.6
Marton, M.J.7
-
10
-
-
0037031145
-
Activation of GCN2 in UV-irradiated cells inhibits translation
-
Deng, J., Harding, H., Raught, B., Gingras, A., Berlanga, J., Scheuner, D., Kaufman, R., Ron, D. & Sonenberg, N. (2002) Activation of GCN2 in UV-irradiated cells inhibits translation. Curr. Biol. 12: 1279-1286.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1279-1286
-
-
Deng, J.1
Harding, H.2
Raught, B.3
Gingras, A.4
Berlanga, J.5
Scheuner, D.6
Kaufman, R.7
Ron, D.8
Sonenberg, N.9
-
11
-
-
0030803256
-
Translational regulation of yeast GCN4 - A window on factors that control initiator-tRNA binding to the ribosome
-
Hinnebusch, A. G. (1997) Translational regulation of yeast GCN4 - a window on factors that control initiator-tRNA binding to the ribosome. J. Biol. Chem. 272: 21661-21664.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21661-21664
-
-
Hinnebusch, A.G.1
-
12
-
-
0036771638
-
The GCN2 elF2alpha kinase is required for adaptation to amino acid deprivation in mice
-
Zhang, P., McGrath, B. C., Reinert, J., Olsen, D. S., Lei, L., Gill, S., Wek, S. A., Vattem, K. M., Wek, R. C., Kimball, S. R., Jefferson, L. S. & Cavener, D. R. (2002) The GCN2 elF2alpha kinase is required for adaptation to amino acid deprivation in mice. Mol. Cell. Biol. 22: 6681-6688.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6681-6688
-
-
Zhang, P.1
McGrath, B.C.2
Reinert, J.3
Olsen, D.S.4
Lei, L.5
Gill, S.6
Wek, S.A.7
Vattem, K.M.8
Wek, R.C.9
Kimball, S.R.10
Jefferson, L.S.11
Cavener, D.R.12
-
13
-
-
0032540217
-
Inhibiton of CCAAT/enhancer-binding protein alpha and beta translation by upstream open reading frames
-
Lincoln, A. J., Monczak, Y., Williams, S. C. & Johnson, P. F. (1998) Inhibiton of CCAAT/enhancer-binding protein alpha and beta translation by upstream open reading frames. J. Biol. Chem. 273: 9552-9560.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9552-9560
-
-
Lincoln, A.J.1
Monczak, Y.2
Williams, S.C.3
Johnson, P.F.4
-
14
-
-
0033533737
-
Role of two upstream open reading frames in the translational control of oncogene mdm2
-
Brown, C. Y., Mize, G. J., Pineda, M., George, D. L. & Morris, D. R. (1999) Role of two upstream open reading frames in the translational control of oncogene mdm2. Oncogene 18: 5631-5637.
-
(1999)
Oncogene
, vol.18
, pp. 5631-5637
-
-
Brown, C.Y.1
Mize, G.J.2
Pineda, M.3
George, D.L.4
Morris, D.R.5
-
15
-
-
0033588103
-
Translational control by an upstream open reading frame in the HER-2/neu transcript
-
Child, S. J., Miller, M. K. & Geballe, A. P. (1999) Translational control by an upstream open reading frame in the HER-2/neu transcript. J. Biol. Chem. 274:24335-24341.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24335-24341
-
-
Child, S.J.1
Miller, M.K.2
Geballe, A.P.3
-
16
-
-
0027510121
-
Cell-specific translational regulation of S-adenosylmethionine decarboxylase mRNA. Dependence on translation and coding capacity of the cis-acting upstream open reading frame
-
Hill, J. R. & Morris, D. R. (1993) Cell-specific translational regulation of S-adenosylmethionine decarboxylase mRNA. Dependence on translation and coding capacity of the cis-acting upstream open reading frame. J. Biol. Chem. 268: 726-731.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 726-731
-
-
Hill, J.R.1
Morris, D.R.2
-
17
-
-
0032484213
-
The inhibitory upstream open reading frame from mammalian S-adenosylmethionine decarboxylase mRNA has a strict sequence specificity in critical positions
-
Mize, G. J., Ruan, H., Low, J. J. & Morris, D. R. (1998) The inhibitory upstream open reading frame from mammalian S-adenosylmethionine decarboxylase mRNA has a strict sequence specificity in critical positions. J. Biol. Chem. 273:32500-32505.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32500-32505
-
-
Mize, G.J.1
Ruan, H.2
Low, J.J.3
Morris, D.R.4
-
18
-
-
0028145741
-
The peptide product of a 5′ leader cistron in the beta 2 adrenergic receptor mRNA inhibits receptor synthesis
-
Parola, A. L. & Kobilka, B. K. (1994) The peptide product of a 5′ leader cistron in the beta 2 adrenergic receptor mRNA inhibits receptor synthesis. J. Biol. Chem. 269: 4497-4505.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4497-4505
-
-
Parola, A.L.1
Kobilka, B.K.2
-
19
-
-
0029822293
-
Regulation of RAR beta 2 mRNA expression: Evidence for an inhibitory peptide encoded in the 5′-untranslated region
-
Reynolds, K., Zimmer, A. M. & Zimmer, A. (1996) Regulation of RAR beta 2 mRNA expression: evidence for an inhibitory peptide encoded in the 5′-untranslated region. J. Cell Biol. 134: 827-835.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 827-835
-
-
Reynolds, K.1
Zimmer, A.M.2
Zimmer, A.3
-
20
-
-
0034745378
-
5′UTR sequences of the glucocorticoid receptor 1A transcript encode a peptide associated with translational regulation of the glucocorticoid receptor
-
Diba, F., Watson, C. S. & Gametchu, B. (2001) 5′UTR sequences of the glucocorticoid receptor 1A transcript encode a peptide associated with translational regulation of the glucocorticoid receptor. J. Cell. Biochem. 81: 149-161.
-
(2001)
J. Cell. Biochem.
, vol.81
, pp. 149-161
-
-
Diba, F.1
Watson, C.S.2
Gametchu, B.3
-
21
-
-
0037020144
-
Upstream open reading frames regulate the translation of the multiple mRNA variants of the estrogen receptor α
-
Ko, M., Denger, S., Reid, G. & Gannon, F. (2002) Upstream open reading frames regulate the translation of the multiple mRNA variants of the estrogen receptor α. J. Biol. Chem. 277: 37131-37138.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37131-37138
-
-
Ko, M.1
Denger, S.2
Reid, G.3
Gannon, F.4
-
22
-
-
0023758546
-
Initiation of protein synthesis by internal entry of ribosomes into the 5′ nontranslated region of encephalomyocarditis virus RNA in vivo
-
Jang, S. K., Davies, M. V., Kaufman, R. J. & Wimmer, E. (1989) Initiation of protein synthesis by internal entry of ribosomes into the 5′ nontranslated region of encephalomyocarditis virus RNA in vivo. J. Virol. 62: 2636-2643.
-
(1989)
J. Virol.
, vol.62
, pp. 2636-2643
-
-
Jang, S.K.1
Davies, M.V.2
Kaufman, R.J.3
Wimmer, E.4
-
23
-
-
0023720048
-
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
-
Pelletier, J. & Sonenberg, N. (1988) Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature 334:320-325.
-
(1988)
Nature
, vol.334
, pp. 320-325
-
-
Pelletier, J.1
Sonenberg, N.2
-
24
-
-
0031741862
-
Two independent internal ribosome entry sites are involved in translation of vascular endothelial growth factor mRNA
-
Huez, I., Creancier, L., Audigier, S., Gensac, M.-C., Prats, A.-C. & Prats, H. (1998) Two independent internal ribosome entry sites are involved in translation of vascular endothelial growth factor mRNA. Mol. Cell. Biol. 18: 6178-6190.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6178-6190
-
-
Huez, I.1
Creancier, L.2
Audigier, S.3
Gensac, M.-C.4
Prats, A.-C.5
Prats, H.6
-
25
-
-
0036000028
-
Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia
-
Lang, K. J., Kappel, A. & Goodall, G. J. (2002) Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia. Mol. Biol. Cell 13: 1792-1801.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1792-1801
-
-
Lang, K.J.1
Kappel, A.2
Goodall, G.J.3
-
26
-
-
0035984186
-
The 5′ untranslated region of protein kinase Cδ directs translation by an internal ribosome entry segment that is most active in densely growing cells and during apoptosis
-
Morrish, B. C. & Rumsby, M. G. (2002) The 5′ untranslated region of protein kinase Cδ directs translation by an internal ribosome entry segment that is most active in densely growing cells and during apoptosis. Mol. Cell. Biol. 22: 6089-6099.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6089-6099
-
-
Morrish, B.C.1
Rumsby, M.G.2
-
27
-
-
0028955936
-
Alternative translation of human fibroblast growth factor-2 mRNA occurs by internal entry of ribosomes
-
Vagner, S., Gensac, M. C., Maret, A., Bayard, F., Amalric, F., Prats, H. & Prats, A.-C. (1995) Alternative translation of human fibroblast growth factor-2 mRNA occurs by internal entry of ribosomes. Mol. Cell. Biol. 15: 35-44.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 35-44
-
-
Vagner, S.1
Gensac, M.C.2
Maret, A.3
Bayard, F.4
Amalric, F.5
Prats, H.6
Prats, A.-C.7
-
28
-
-
0033956750
-
c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis
-
Stoneley, M., Chappell, S. A., Jopling, C. L., Dickens, M., MacFarlane, M. & Willis, A. E. (2000) c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis. Mol. Cell. Biol. 20: 1162-1169.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1162-1169
-
-
Stoneley, M.1
Chappell, S.A.2
Jopling, C.L.3
Dickens, M.4
MacFarlane, M.5
Willis, A.E.6
-
29
-
-
0033160190
-
A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection
-
Holcik, M., Lefebvre, C., Yeh, C., Chow, T. & Korneluk, R. G. (1999) A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection. Nat. Cell Biol. 1: 190-192.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 190-192
-
-
Holcik, M.1
Lefebvre, C.2
Yeh, C.3
Chow, T.4
Korneluk, R.G.5
-
30
-
-
0033980394
-
A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation
-
Henis-Korenblit, S., Strumpf, N. L., Goldstaub, D. & Kimchi, A. (2000) A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation. Mol. Cell. Biol. 20: 496-506.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 496-506
-
-
Henis-Korenblit, S.1
Strumpf, N.L.2
Goldstaub, D.3
Kimchi, A.4
-
31
-
-
0033634723
-
A cell cycle-dependent internal ribosome entry site
-
Pyronnet, S., Pradayrol, L. & Sonenberg, N. (2000) A cell cycle-dependent internal ribosome entry site. Mol. Cell 5: 607-616.
-
(2000)
Mol. Cell
, vol.5
, pp. 607-616
-
-
Pyronnet, S.1
Pradayrol, L.2
Sonenberg, N.3
-
32
-
-
0001836537
-
Cellular internal ribosome entry site elements and the use of cDNA microarrays in their investigation
-
Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Carter, M. S., Kuhn, K. M. & Sarnow, P. (2000) Cellular internal ribosome entry site elements and the use of cDNA microarrays in their investigation. In: Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds.), pp. 615-635. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational Control of Gene Expression
, pp. 615-635
-
-
Carter, M.S.1
Kuhn, K.M.2
Sarnow, P.3
-
33
-
-
0035853762
-
Internal ribosome entry site-mediated translation of a mammalian mRNA is regulated by amino acid availability
-
Fernandez, J., Yaman, I., Mishra, R., Merrick, W. C., Snider, M. D., Lamers, W. H. & Hatzoglou, M. (2001) Internal ribosome entry site-mediated translation of a mammalian mRNA is regulated by amino acid availability. J. Biol. Chem. 276: 12285-12291.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12285-12291
-
-
Fernandez, J.1
Yaman, I.2
Mishra, R.3
Merrick, W.C.4
Snider, M.D.5
Lamers, W.H.6
Hatzoglou, M.7
-
34
-
-
0037023688
-
Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner
-
Fernandez, J., Bode, B., Koromilias, A., Diehl, J. A., Krukovets, I., Snider, M. D. & Hatzoglou, M. (2002) Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner. J. Biol. Chem. 277: 11780-11787.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11780-11787
-
-
Fernandez, J.1
Bode, B.2
Koromilias, A.3
Diehl, J.A.4
Krukovets, I.5
Snider, M.D.6
Hatzoglou, M.7
-
35
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle, T. & Hall, M. N. (2000) TOR, a central controller of cell growth. Cell 103: 253-262.
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
36
-
-
0030707562
-
TOR signaling and control of cell growth
-
Thomas, G. & Hall, M. N. (1997) TOR signaling and control of cell growth. Curr. Opin. Cell Biol. 9: 782-787.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 782-787
-
-
Thomas, G.1
Hall, M.N.2
-
37
-
-
0035312747
-
Regulation of translation initiation by FRAP/mTOR
-
Gingras, A.-C., Raught, B. & Sonenberg, N. (2001) Regulation of translation initiation by FRAP/mTOR. Genes Dev. 15: 807-826.
-
(2001)
Genes Dev.
, vol.15
, pp. 807-826
-
-
Gingras, A.-C.1
Raught, B.2
Sonenberg, N.3
-
38
-
-
0001902617
-
Regulation of ribosomal recruitment in eukaryotes
-
Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Raught, B., Gingras, A.-C. & Sonenberg, N. (2000) Regulation of ribosomal recruitment in eukaryotes. In: Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds.), pp. 245-293. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational Control of Gene Expression
, pp. 245-293
-
-
Raught, B.1
Gingras, A.-C.2
Sonenberg, N.3
-
39
-
-
0033565233
-
Repressor binding to a dorsal regulatory site traps human elF4E in a high cap-affinity state
-
Ptushkina, M., von der Haar, T., Karim, M. M., Hughes, J. M. X. & McCarthy, J. E. G. (1999) Repressor binding to a dorsal regulatory site traps human elF4E in a high cap-affinity state. EMBO J. 18: 4068-4075.
-
(1999)
EMBO J.
, vol.18
, pp. 4068-4075
-
-
Ptushkina, M.1
Von der Haar, T.2
Karim, M.M.3
Hughes, J.M.X.4
McCarthy, J.E.G.5
-
40
-
-
0032561348
-
Branched-chain amino acids are essential in the regulation of PHAS-I and p70 S6 kinase by pancreatic β-cells
-
Xu, G., Kwon, G., Marshall, C. A., Lin, T.-A., Lawrence, J. C. & McDaniel, M. L. (1998) Branched-chain amino acids are essential in the regulation of PHAS-I and p70 S6 kinase by pancreatic β-cells. J. Biol. Chem. 273: 28178-28184.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28178-28184
-
-
Xu, G.1
Kwon, G.2
Marshall, C.A.3
Lin, T.-A.4
Lawrence, J.C.5
McDaniel, M.L.6
-
41
-
-
0033597129
-
Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of elF4E and phosphorylation of ribosomal protein S6
-
Kimball, S. R., Shantz, L. M., Horetsky, R. L. & Jefferson, L. S. (1999) Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of elF4E and phosphorylation of ribosomal protein S6. J. Biol. Chem. 274: 11647-11652.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11647-11652
-
-
Kimball, S.R.1
Shantz, L.M.2
Horetsky, R.L.3
Jefferson, L.S.4
-
42
-
-
0031730932
-
Effect of dietary protein on translation initiation in rat skeletal muscle and liver
-
Yoshizawa, F., Kimball, S. R., Vary, T. C. & Jefferson, L. S. (1998) Effect of dietary protein on translation initiation in rat skeletal muscle and liver. Am. J. Physiol. Endocrinol. Metab. 275: E814-E820.
-
(1998)
Am. J. Physiol. Endocrinol. Metab.
, vol.275
-
-
Yoshizawa, F.1
Kimball, S.R.2
Vary, T.C.3
Jefferson, L.S.4
-
43
-
-
0033980371
-
Orally administered leucine stimulates protein synthesis in skeletal muscle of post-absorptive rats in association with increased elF4F formation
-
Anthony, J. C., Anthony, T. G., Kimball, S. R., Vary, T. C. & Jefferson, L. S. (2000) Orally administered leucine stimulates protein synthesis in skeletal muscle of post-absorptive rats in association with increased elF4F formation. J. Nutr. 130: 139-145.
-
(2000)
J. Nutr.
, vol.130
, pp. 139-145
-
-
Anthony, J.C.1
Anthony, T.G.2
Kimball, S.R.3
Vary, T.C.4
Jefferson, L.S.5
-
44
-
-
0033635106
-
Developmental changes in the feeding-induced stimulation of translation initiation in muscle of neonatal pigs
-
Davis, T. A., Nguyen, H. V., Suryawan, A., Bush, J., Jefferson, L. S. & Kimball, S. R. (2000) Developmental changes in the feeding-induced stimulation of translation initiation in muscle of neonatal pigs. Am. J. Physiol. Endocrinol. Metab. 279: E1226-E1234.
-
(2000)
Am. J. Physiol. Endocrinol. Metab.
, vol.279
-
-
Davis, T.A.1
Nguyen, H.V.2
Suryawan, A.3
Bush, J.4
Jefferson, L.S.5
Kimball, S.R.6
-
45
-
-
0035018506
-
Branched chain amino acids activate messenger ribonucleic acid translation regulatory proteins in human skeletal muscle, and glucocorticoids blunt this action
-
Liu, Z., Jahn, L. A., Long, W., Fryburg, D. A., Wei, L. & Barrett, E. J. (2001) Branched chain amino acids activate messenger ribonucleic acid translation regulatory proteins in human skeletal muscle, and glucocorticoids blunt this action. J. Clin. Endocrinol. Metab. 86: 2136-2143.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 2136-2143
-
-
Liu, Z.1
Jahn, L.A.2
Long, W.3
Fryburg, D.A.4
Wei, L.5
Barrett, E.J.6
-
46
-
-
0033808169
-
Leucine stimulates translation initiation in skeletal muscle of post-absorptive rats via a rapamycin-sensitive pathway
-
Anthony, J. C., Yoshizawa, F., Anthony, T. G., Vary, T. C., Jefferson, L. S. & Kimball, S. R. (2000) Leucine stimulates translation initiation in skeletal muscle of post-absorptive rats via a rapamycin-sensitive pathway. J. Nutr. 130: 2413-2419.
-
(2000)
J. Nutr.
, vol.130
, pp. 2413-2419
-
-
Anthony, J.C.1
Yoshizawa, F.2
Anthony, T.G.3
Vary, T.C.4
Jefferson, L.S.5
Kimball, S.R.6
-
47
-
-
0033668261
-
Feeding stimulates protein synthesis in muscle and liver of neonatal pigs through an mTOR-dependent process
-
Kimball, S. R., Jefferson, L. S. & Davis, T. A. (2000) Feeding stimulates protein synthesis in muscle and liver of neonatal pigs through an mTOR-dependent process. Am. J. Physiol. Endocrinol. Metab. 279: E1080-E1087.
-
(2000)
Am. J. Physiol. Endocrinol. Metab
, vol.279
-
-
Kimball, S.R.1
Jefferson, L.S.2
Davis, T.A.3
-
48
-
-
0001798492
-
S6 phosphorylation and signal transduction
-
Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Fumagalli, S. & Thomas, G. (2000) S6 phosphorylation and signal transduction. In: Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds.), pp. 695-717. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational Control of Gene Expression
, pp. 695-717
-
-
Fumagalli, S.1
Thomas, G.2
-
49
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett, P. E., Barrow, R. K., Cohen, N. A., Snyder, S. H. & Sabatini, D. M. (1998) RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl. Acad. Sci. U.S.A. 95: 1432-1437.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Barrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
50
-
-
0002921709
-
Translational control of TOP mRNAs
-
Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Meyuhas, O. & Hornstein, E. (2000) Translational control of TOP mRNAs. In: Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B. & Mathews, M. B., eds.), pp. 671-693. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(2000)
Translational Control of Gene Expression
, pp. 671-693
-
-
Meyuhas, O.1
Hornstein, E.2
-
51
-
-
0027931137
-
Modulation of transcription of rRNA genes by rapamycin
-
Mahajan, P. B. (1994) Modulation of transcription of rRNA genes by rapamycin. J. Immunopharmacol. 16: 711-721.
-
(1994)
J. Immunopharmacol.
, vol.16
, pp. 711-721
-
-
Mahajan, P.B.1
-
52
-
-
0035200856
-
Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation
-
Tang, H., Hornstein, E., Stolovich, M., Levy, G., Livingstone, M., Templeton, D., Avruch, J. & Meyuhas, O. (2001) Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation. Mol. Cell. Biol. 21: 8671-8683.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 8671-8683
-
-
Tang, H.1
Hornstein, E.2
Stolovich, M.3
Levy, G.4
Livingstone, M.5
Templeton, D.6
Avruch, J.7
Meyuhas, O.8
-
54
-
-
0036230645
-
Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation
-
Anthony, J. C., Reiter, A. K., Anthony, T. G., Crozier, S. J., Lang, C. H., MacLean, D. A., Kimball, S. R. & Jefferson, L. S. (2002) Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation. Diabetes 51: 928-936.
-
(2002)
Diabetes
, vol.51
, pp. 928-936
-
-
Anthony, J.C.1
Reiter, A.K.2
Anthony, T.G.3
Crozier, S.J.4
Lang, C.H.5
MacLean, D.A.6
Kimball, S.R.7
Jefferson, L.S.8
-
55
-
-
0034836597
-
Amino acids and insulin are both required to regulate assembly of the elF4E•elF4G complex in rat skeletal muscle
-
Balage, M., Sinaud, S., Prod'Homme, M., Dardevet, D., Vary, T. C., Kimball, S. R., Jefferson, L. S. & Grizard, J. (2001) Amino acids and insulin are both required to regulate assembly of the elF4E•elF4G complex in rat skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 281: E565-E574.
-
(2001)
Am. J. Physiol. Endocrinol. Metab.
, vol.281
-
-
Balage, M.1
Sinaud, S.2
Prod'Homme, M.3
Dardevet, D.4
Vary, T.C.5
Kimball, S.R.6
Jefferson, L.S.7
Grizard, J.8
-
56
-
-
0036712905
-
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
-
Gao, X., Zhang, Y., Arrazola, P., Hino, O., Kobayashi, T., Yeung, R. S., Ru, B. & Pan, D. (2002) Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Nat. Cell Biol. 4: 699-704.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 699-704
-
-
Gao, X.1
Zhang, Y.2
Arrazola, P.3
Hino, O.4
Kobayashi, T.5
Yeung, R.S.6
Ru, B.7
Pan, D.8
-
57
-
-
0027770784
-
Identification and characterization of the tuberous sclerosis gene on chromosome 16
-
The European Chromosome 16 Tuberous Sclerosis Consortium
-
Anonymous (1993) Identification and characterization of the tuberous sclerosis gene on chromosome 16. The European Chromosome 16 Tuberous Sclerosis Consortium. Cell 75: 1305-1315.
-
(1993)
Cell
, vol.75
, pp. 1305-1315
-
-
-
58
-
-
0030879277
-
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34
-
van Slegtenhorst, M., de Hoogt, R., Hermans, C., Nellist, M., Janssen, B., Verhoef, S., Lindhout, D., van den Ouweland, A., Halley, D., Young, J., Burley, M., Jeremiah, S., Woodward, K., Nahmias, J., Fox, M., Ekong, R., Osborne, J., Wolfe, J., Povey, S., Snell, R. G., Cheadle, J. P., Jones, A. C., Tachataki, M., Ravine, D. & Kwiatkowski, D. J. (1997) Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science 277: 805-808.
-
(1997)
Science
, vol.277
, pp. 805-808
-
-
Van Slegtenhorst, M.1
De Hoogt, R.2
Hermans, C.3
Nellist, M.4
Janssen, B.5
Verhoef, S.6
Lindhout, D.7
Van den Ouweland, A.8
Halley, D.9
Young, J.10
Burley, M.11
Jeremiah, S.12
Woodward, K.13
Nahmias, J.14
Fox, M.15
Ekong, R.16
Osborne, J.17
Wolfe, J.18
Povey, S.19
Snell, R.G.20
Cheadle, J.P.21
Jones, A.C.22
Tachataki, M.23
Ravine, D.24
Kwiatkowski, D.J.25
more..
-
59
-
-
0036712741
-
TSC1-TSC2: A complex tale of PKB-mediated S6K regulation
-
McManus, E. J. & Alessi, D. R. (2002) TSC1-TSC2: a complex tale of PKB-mediated S6K regulation. Nat. Cell Biol. 4: E214-E216.
-
(2002)
Nat. Cell Biol.
, vol.4
-
-
McManus, E.J.1
Alessi, D.R.2
-
60
-
-
0034982971
-
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
-
Gao, X. & Pan, D. (2001) TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev. 15: 1383-1392.
-
(2001)
Genes Dev.
, vol.15
, pp. 1383-1392
-
-
Gao, X.1
Pan, D.2
-
61
-
-
0035805162
-
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
-
Potter, C. J., Huang, H. & Xu, T. (2001) Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 105: 357-368.
-
(2001)
Cell
, vol.105
, pp. 357-368
-
-
Potter, C.J.1
Huang, H.2
Xu, T.3
-
62
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling
-
Inoki, K., Li, Y., Zhu, T., Wu, J. & Guan, K.-L. (2002) TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling. Nat. Cell Biol. 4: 648-657.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.-L.5
-
63
-
-
0036714127
-
Akt regulates growth by directly phosphorylating Tsc2
-
Potter, C. J., Pedraza, L. G. & Xu, T. (2002) Akt regulates growth by directly phosphorylating Tsc2. Nat. Cell Biol. 4: 658-665.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 658-665
-
-
Potter, C.J.1
Pedraza, L.G.2
Xu, T.3
-
64
-
-
0036342294
-
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway
-
Manning, B. D., Tee, A. R., Logsdon, M. N., Blenis, J. & Cantley, L. C. (2002) Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway. Mol. Cell 10: 151-162.
-
(2002)
Mol. Cell
, vol.10
, pp. 151-162
-
-
Manning, B.D.1
Tee, A.R.2
Logsdon, M.N.3
Blenis, J.4
Cantley, L.C.5
-
65
-
-
0037163033
-
Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)
-
Goncharova, E. A., Goncharov, D. A., Eszterhas, A., Hunter, D. S., Glassberg, M. K., Yeung, R. S., Walker, C. L., Noonan, D., Kwiatkowski, D. J., Chou, M. M., Panettieri, R. A., Jr. & Krymskaya, V. P. (2002) Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM). J. Biol. Chem. 277: 30958-30967.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30958-30967
-
-
Goncharova, E.A.1
Goncharov, D.A.2
Eszterhas, A.3
Hunter, D.S.4
Glassberg, M.K.5
Yeung, R.S.6
Walker, C.L.7
Noonan, D.8
Kwiatkowski, D.J.9
Chou, M.M.10
Panettieri R.A., Jr.11
Krymskaya, V.P.12
-
66
-
-
0036501277
-
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
-
Kwiatkowski, D. J., Zhang, H., Bandura, J. L., Heiberger, K. M., Glogauer, M., el-Hashemite, N. & Onda, H. (2002) A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum. Mol. Genet. 11: 525-534.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 525-534
-
-
Kwiatkowski, D.J.1
Zhang, H.2
Bandura, J.L.3
Heiberger, K.M.4
Glogauer, M.5
El-Hashemite, N.6
Onda, H.7
-
67
-
-
0037108750
-
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
-
Tee, A. R., Fingar, D. C., Manning, B. D., Kwiatkowski, D. J., Cantley, L. C. & Blenis, J. (2002) Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proc. Natl. Acad. Sci. U.S.A. 99: 13571-13576.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 13571-13576
-
-
Tee, A.R.1
Fingar, D.C.2
Manning, B.D.3
Kwiatkowski, D.J.4
Cantley, L.C.5
Blenis, J.6
-
68
-
-
0037020044
-
Identification of TOR signaling complexes: More TORC for the cell growth engine
-
Abraham, R. T. (2002) Identification of TOR signaling complexes: More TORC for the cell growth engine. Cell 111: 9-12.
-
(2002)
Cell
, vol.111
, pp. 9-12
-
-
Abraham, R.T.1
-
69
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (mTOR), mediates TOR action
-
Hara, K., Maruki, Y., Long, X., Yoshino, K, Oshiro, N., Hidayat, S., Tokunaga, C., Avruch, J. & Yonezawa, K. (2002) Raptor, a binding partner of target of rapamycin (mTOR), mediates TOR action. Cell 110: 177-189.
-
(2002)
Cell
, vol.110
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.4
Oshiro, N.5
Hidayat, S.6
Tokunaga, C.7
Avruch, J.8
Yonezawa, K.9
-
70
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim, D.-H., Sarbassov, D. D., Ali, S. M., King, J. E., Latek, R. R., Erdjument-Bromage, H., Tempst, P. & Sabatini, D. M. (2002) mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110: 163-175.
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.-H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
71
-
-
0036753494
-
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
-
Loewith, R., Jacinto, E., Wullscheleger, S., Lorberg, A., Crespo, J. L., Bonenfant, D., Oppliger, W., Jenoe, P. & Hall, M. N. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol. Cell 10: 457-468.
-
(2002)
Mol. Cell
, vol.10
, pp. 457-468
-
-
Loewith, R.1
Jacinto, E.2
Wullscheleger, S.3
Lorberg, A.4
Crespo, J.L.5
Bonenfant, D.6
Oppliger, W.7
Jenoe, P.8
Hall, M.N.9
|