Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis

Journal of Experimental Medicine

Volumn 200, Issue 3, 2004, Pages 353-365

  Gajate, Consuelo ^a   Del Canto Jañez, Esther ^a   Acuña, A Ulises ^b   Amat Guerri, Francisco ^c   Geijo, Emilio ^d   Santos Beneit, Antonio M ^a   Veldman, Robert J ^a   Mollinedo, Faustino ^a,e  

^a Centro de Investigacion del Cancer   (Spain)

^b INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

^c INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^d MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^e UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Antitumor ether lipid; CD95; Death receptor; ET 18 OCH 3; Fas signaling

Indexed keywords

ANTINEOPLASTIC AGENT; ANTITUMOR ETHER LIPID; CASPASE 8; CASPASE 9; CERAMIDE; DNA; EDELFOSINE; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; PROTEIN BID; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CELL STRAIN U937; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA DAMAGE; DRUG UPTAKE; ENZYME ACTIVATION; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TUMOR CELL; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; HEPATOCYTES; HL-60 CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE MICRODOMAINS; PHOSPHOLIPID ETHERS; PROTEIN BIOSYNTHESIS; RATS; SPHINGOMYELIN PHOSPHODIESTERASE; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 3543078747     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040213     Document Type: Article

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