Altered APP processing in PDAPP (Val717 → Phe) transgenic mice yields extended-length Aβ peptides

Biochemistry

Volumn 44, Issue 42, 2005, Pages 13807-13819

  Esh, Chera ^a   Patton, Lyle ^a   Kalback, Walter ^a   Kokjohn, Tyler A ^a,b   Lopez, John ^c   Brune, Daniel ^c   Newell, Amanda J ^a   Beach, Thomas ^a   Schenk, Dale ^d   Games, Dora ^d   Paul, Steven ^e   Bales, Kelly ^e   Ghetti, Bernardino ^f   Castaño, Eduardo M ^g   Roher, Alex E ^a  

^a SUN HEALTH RESEARCH INSTITUTE   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

^d ELAN PHARMACEUTICALS   (United States)

^e ELI LILLY AND COMPANY   (United States)

^f INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g FUNDACIÓN INSTITUTO LELOIR   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; MASS SPECTROMETRY; PROTEINS; TISSUE;

AMYLOID PRECURSOR PROTEINS (APP); DETERGENT LYSIS; HUMAN TRANSGENE;

BIOCHEMISTRY;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; PHENYLALANINE; PLATELET DERIVED AMYLOID PRECURSOR PROTEIN; UNCLASSIFIED DRUG; VALINE;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; AMYLOIDOSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BRAIN TISSUE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FAST PROTEIN LIQUID CHROMATOGRAPHY; GENE MUTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOPRECIPITATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR MODEL; MOUSE; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN STRUCTURE; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; TRANSGENE; TRANSGENIC MOUSE; ULTRACENTRIFUGATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

ANIMALIA; MUS MUSCULUS;

EID: 27144553121     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051213+     Document Type: Article

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