Transcriptional Activity of Notch and CSL Proteins

Handbook of Cell Signaling: Volume 1-3

Volumn 1-3, Issue , 2003, Pages 149-159

  Lamar, Elise ^a   Kintner, Chris ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 24944531462     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012124546-7/50656-2     Document Type: Chapter

References (113)

1. T. Gridley (1997) Notch signaling in vertebrate development and disease. Mol. Cell Neurosci. 9 103-108.
2. J. Kimble and P. Simpson (1997) The LIN12/Notch signaling pathway and its regulation. Ann. Rev. Cell Dev. Biol. 13 333-361.
3. S. Artavanis-Tsakonas, M. Rand and R. Lake (1999) Notch signaling: Cell fate control and signal integration in development. Science 284 770-776.
4. J. Mumm and R. Kopan (2000) Notch signaling: From the outside in. Dev. Biol. 228 151-165.
5. M.L. Deftos and M.J. Bevan (2000) Notch signaling in T cell development. Curr. Opin. Immunol. 12 166-172.
6. R. Kopan (2002) Notch: A membrane-bound transcription factor. J. Cell Sci. 115 1095-1097.
7. D. Allman, J.A. Punt, D.J. Izon, J.C. Aster and W.S. Pear (2002) An invitation to T and more: Notch signaling in lymphopoiesis. Cell 109 1-11.
8. N.J. Justice and Y.N. Jan (2002) Variations on the Notch pathway in neural development. Curr. Opin. Neurobiol. 12 64-70.
9. G. Struhl and A. Adachi (1998) Nuclear access and action of Notch in vivo. Cell 93 649-660.
10. E. Schroeter, J. Kisslinger and R. Kopan (1998) Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393 382-386.
11. S. Bray and M. Furriols (2001) Notch pathway: Making sense of Suppressor of Hairless. Curr. Biol. 11 R217-R221.
12. S. Barolo and J.W. Posakony (2002) Three habits of highly effective signaling pathways: Principles of transcriptional control by developmental cell signaling. Genes Dev. 16 1167-1181.
13. C. Shawber, D. Nofziger, J. Hsieh, C. Lindsell, O. Bogler, D. Hayward and G. Weinmaster (1996) Notch signalling inhibits muscle cell differentiation through a CBF1-independent pathway. Development 122 3765-3773.
14. P. Ordentlich, A. Lin, C. Shen, C. Blaumueller, K. Matsuno, S. Artavanis-Tsakonas and T. Kadesch (1998) Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol. Cell Biol. 18 2230-2239.
15. G. Bush, G. diSibio, A. Miyamoto, J.B. Denault, R. Leduc and G. Weinmaster (2001) Ligand-induced signaling in the absence of furin processing of Notch1. Dev. Biol. 229 494-502.
16. P. Ramain, K. Khechumian, L. Seugnet, N. Arbogast, C. Ackermann and P. Heitzler (2001) Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate. Curr. Biol. 11 1729-1738.
17. D.A. Ross and T. Kadesch (2001) The Notch intracellular domain can function as a coactivator for LEF-1. Mol. Cell Biol. 21 7537-7544.
18. G. Weinmaster (1997) The ins and outs of Notch signaling. Mol. Cell Neurosci. 9 91-102.
19. P. Beatus, J. Lundkvist, C. Oberg and U. Lendahl (1999) The Notch 3 intracellular domain represses Notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters. Development 126 3925-3935.
20. K. Tamura, Y. Taniguchi, S. Minoguchi, T. Sakai, T. Tun, T. Furukawa and T. Honjo (1995) Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H). Curr. Biol. 5 1416-1423.
21. H. Kato, Y. Taniguchi, H. Kurooka, S. Minoguchi, T. Sakai, S. Nomura-Okazaki, K. Tamura and T. Honjo (1997) Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. Development 124 4133-4141.
22. M.E. Zweifel and D. Barrick (2001) Studies of the ankyrin repeats of the Drosophila melanogaster Notch receptor. 1. Solution conformational and hydrodynamic properties. Biochemistry 40 14344-14356.
23. S. Jeffries, D.J. Robbins and A.J. Capobianco (2002) Characterization of a high-molecular weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Mol. Cell Biol. 22 3927-3941.
24. M. Rechsteiner and S.W. Rogers (1996) PEST sequences and regulation by proteolysis. Trends Biochem. Sci. 21 267-271.
25. T. Tun, Y. Hamaguchi, N. Matsunami, T. Furukawa, T. Honjo and M. Kawaichi (1994) Recognition sequence of a highly conserved DNA binding protein RBP-Jκ. Nucl. Acids Res. 22 965-971.
26. R. Davis, D. Turner, L. Evans and M. Kirschner (2001) Molecular targets of vertebrate segmentation: Two mechanisms control segmental expression of Xenopus hairy2 during somite formation. Dev. Cell 1 553-565.
27. S. Jarriault, C. Brou, F. Logeat, E.H. Schroeter, R. Kopan and A. Israel (1995) Signalling downstream of activated mammalian Notch. Nature 377 355-358.
28. D.T. Nellesen, E.C. Lai and J.W. Posakony (1999) Discrete enhancer elements mediate selective responsiveness of Enhancer of split Complex genes to common transcriptional activators. Dev. Biol. 213 33-53.
29. A. Bailey and J.W. Posakony (1995) Suppressor of Hairless directly activates transcription of Enhancer of split Complex genes in response to Notch receptor activity. Genes Dev. 9 2609-2622.
30. G.V. Flores, H. Duan, H. Yan, R. Nagaraj, W. Fu, Y. Zou, M. Noll and U. Banerejee (2000) Combinatorial signaling in the specification of unique cell fates. Cell 103 75-85.
31. J. Kim, A. Sebring, J. Esch, M.E. Kraus, K. Vorwerk, J. Magee and S.B. Carroll (1996) Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382 133-138.
32. L.T. Lam and E.H. Bresnick (1998) Identity of the β-globin loculs control region binding protein HS2NF5 as the mammalian homolog of the Notch-regulated transcription factor Suppressor of Hairless. J. Biol. Chem. 273 24223-24231.
33. I. Olave, D. Reinberg and L.D. Vales (1998) The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription. Genes Dev. 12 1621-1637.
34. H.-Y. Kao, P. Ordentlich, N. Koyano-Nakagawa, Z. Tang, M. Downes, C. Kintner, R. Evans and T. Kadesch (1998) A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev. 12 2269-2277.
35. J.-D. Hsieh, S. Zhou, L. Chen, D.B. Young and S.D. Hayward (1999) CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. Proc. Natl. Acad. Sci. USA 96 23-28.
36. Y. Taniguchi, T. Furukawa, T. Tun, H. Han and T. Honjo (1998) LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein. Mol. Cell Biol. 18 644-654.
37. A.G. Bang and J.W. Posakony (1992) The Drosophila gene Hairless encodes a novel basic protein that controls alternative cell fates in adult sensory organ development. Genes Dev. 6 1752-1769.
38. A.G. Bang, A.M. Bailey and J.W. Posakony (1995) Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulating the activity of the Notch signlaing pathway. Dev. Biol. 172 479-494.
39. D. Maier, G. Stumm, K. Kuhn and A. Preiss (1992) Hairless, a Drosophila gene involved in neural development, encodes a novel, serine rich protein. Mech. Dev. 38 143-156.
40. V. Morel, M. Lecourtois, O. Massiani, D. Maier, A. Preiss and F. Schweisguth (2001) Transcriptional repression by Suppressor of hairless involves the binding of a Hairless-dCtBP complex in Drosophila. Curr. Biol. 11 789-792.
41. S. Barolo, T. Stone, A.G. Bang and J.W. Posakony (2002) Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless. Genes Dev. 16 1964-1976.
42. A.J. Courey and S. Jia (2001) Transcriptional repression: The long and the short of it. Genes Dev. 15 2786-2796.
43. A. Rangarajan, C. Talora, R. Okuyama, M. Nicolas, C. Mammucari, H. Oh, J. Aster, S. Krishna, D. Metzger, P. Chambon, L. Miele, M. Aguet, F. Radtke and G. Dotto (2001) Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J. 20 3427-3436.
44. V. Morel and F. Schweisguth (2000) Repression by Suppressor of hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo. Genes Dev. 14 377-388.
45. H. Kurooka, K. Kuroda and T. Honjo (1998) Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region. Nucl. Acids Res. 26 5448-5455.
46. H. Kurooka and T. Honjo (2000) Functional interaction between the mouse Notch 1 intracellular region and histone acetyltransferases PCAF and GCN5. J. Biol. Chem. 275 17211-17220.
47. F. Oswald, B. Tauber, T. Dobner, S. Bourteele, U. Kostezka, G. Adler, S. Liptay and R.M. Schmid (2001) p300 Acts as a transcriptional coactivator for mammalian Notch-1. Mol. Cell Biol. 21 7761-7774.
48. D. Wettstein, D. Turner and C. Kintner (1997) The Xenopus homolog of Drosophila Suppressor of Hairless mediates Notch signaling during primary neurogenesis. Development 124 3693-3702.
49. C.J. Fryer, E. Lamar, I. Turbachova, C. Kintner and K.A. Jones (2002) Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev. 16 1397-1411.
50. J.C. Aster, L. Xu, F.G. Karnell, V. Patriub, J.C. Pui and W.S. Pear (2000) Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1. Mol. Cell Biol. 20 7505-7515.
51. A.G. Petcherski and J. Kimble (2000) Mastermind is a putative activator for Notch. Curr. Biol. 10 R471-R473.
52. L. Wu, J. Aster, S. Blacklow, R. Lake, S. Artavanis-Tsakonas and J. Griffin (2000) MAML1, a human homologue of Drosophila Mastermind is a transcriptional coactivator for NOTCH receptors. Nature Genet. 26 484-489.
53. M. Kitagawa, T. Oyama, T. Kawashima, B. Yedvobnick, A. Kumar, K. Matsuno and K. Harigaya (2001) A human protein with sequence similarity to Drosophila Mastermind coordinates the nuclear form of Notch and a CSL protein to build a transcriptional activator complex on target promoters. Mol. Cell Biol. 21 4337-4346.
54. W. Helms, H. Lee, M. Ammerman, A.L. Parks, M.A. Muskavitch and B. Yedvobnick (1999) Engineered truncations in the Drosophila mastermind protein disrupt Notch pathway function. Dev. Biol. 215 358-374.
55. A.J. Giraldez, L. Perez and S.M. Cohen (2002) A naturally occurring alternative product of the mastermind locus that represses notch signalling. Mech. Dev. 115 101-105.
56. E.H. Bresnick, J. Chu, H. Christensen, B. Lin and J. Norton (2000) Linking Notch signaling, chromatin remodeling, and T-cell leukemogenesis. J. Cell Biochem. Supp. 35 46-53.
57. E. Lamar, G. Deblandre, D. Wettstein, V. Gawantka, N. Pollet, C. Niehrs and C. Kintner (2001) Nrarp is a novel intracellular component of the Notch signaling pathway. Genes Dev. 15 1885-1899.
58. L. Krebs, M. Deftos, M. Bevan and T. Gridley (2001) The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the Notch signaling pathway. Dev. Biol. 238 110-119.
59. K. Lahaye, S. Kricha and E. Bellefroid (2002) XNAP, a conserved ankyrin repeat-containing protein with a role in the Notch pathway during Xenopus primary neurogenesis. Mech. Dev. 110 113-124.
60. S. Zhou, M. Fujimuro, J. Hsieh, L. Chen and S.D. Hayward (2000) A role for SKIP in EBNA-2 activation of CBF1-repressed promoters. J. Virol. 74 1939-1947.
61. C. Zhang, T.A. Baudino, D.R. Dowd, H. Tokumaru, W. Wang and P.N. MacDonald (2001) Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription. J. Biol. Chem. 276 40614-40620.
62. G.M. Leong, N. Subramaniam, J. Figueroa, J.L. Flanagan, M.J. Hayman, J.A. Eisman and A.P. Kouzmenko (2001) Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-β-dependent transcription. J. Biol. Chem. 276 18243-18248.
63. K. Matsuno, R. Diederich, M. Go, C. Blaumueller and S. Artavanis-Tsakonas (1995) Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development 121 2633-2644.
64. K. Matsuno, M. Ito, K. Hori, F. Miyashita, S. Suzuki, N. Kishi, S. Artavanis-Tsakonas and H. Okano (2002) Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. Development 129 1049-1059.
65. R.J. Diederich, K. Matsuno, H. Hing and S. Artavanis-Tsakonas (1994) Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. Development 120 473-481.
66. N. Yamamoto, S. Yamamoto, F. Inagaki, M. Kawaichi, A. Fukamizu, N. Kishi, K. Matsuno, K. Nakamura, G. Weinmaster, H. Okano and M. Nakafuku (2001) Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. J. Biol. Chem. 276 45031-45040.
67. T. Xu, I. Rebay, R. Fleming, T. Scottgale and S. Artavanis-Tsakonas (1990) The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis. Genes Dev. 4 464-475.
68. N. Sestan, S. Artavanis-Tsakonas and P. Rakic (1999) Contact-dependent inhibition of cortical neurite growth mediated by Notch signaling. Science 286 741-746.
69. D.J. Izon, J.C. Aster, Y. He, A. Weng, F.G. Karnell, V. Patriub, L. Xu, S. Bakkour, C. Rodriguez, D. Allman and W.S. Pear (2002) Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. Immunity 16 231-243.
70. S. Kidd, T. Lieber and M.W. Young (1998) Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. Genes Dev. 12 3728-3740.
71. K. Shimizu, S. Chiba, N. Hosoya, K. Kumano, T. Saito, M. Kurokawa, Y. Kanda, Y. Hamada and H. Hirai (2000) Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2. Mol. Cell Biol. 20 6913-6922.
72. D.R. Foltz and J.S. Nye (2001) Hyperphosphorylation and association with RBP of the intracellular domain of Notch1. BBRC 286 484-492.
73. L. Redmond, S.-R. Oh, C. Hicks, G. Weinmaster and A. Ghosh (2000) Nuclear Notch1 signaling and the regulation of dendritic development. Nature Neurosci. 3 30-40.
74. N. Gupta-Rossi, O. LeBail, H. Gonen, C. Brou, F. Logeat, E. Six, A. Ciechanover and A. Israel (2001) Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor. J. Biol. Chem. 276 34371-34378.
75. J. Ingles-Esteve, L. Espinosa, L.A. Milner, C. Caelles and A. Bigas (2001) Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation. J. Biol. Chem. 276 44873-44880.
76. D.R. Foltz, M.C. Santiago, B.E. Berechid and J.S. Nye (2002) Glycogen synthase kinase-3β modulates Notch signaling and stability. Curr. Biol. 12 1006-1011.
77. R.C. Conaway, C.S. Brower and J.W. Conaway (2002) Emerging roles of ubiquitin in transcription regulation. Science 296 1254-1258.
78. E. Yeh, M. Dermer, C. Commisso, L. Zhou, C.J. McGlade and G.L. Boulianne (2001) Neuralized functions as an E3 ubiquitin ligase during Drosophila development. Curr. Biol. 11 1675-1679.
79. G. Deblandre, E. Lai and C. Kintner (2001) Xenopus Neuralized is a ubiquitin ligase that interacts with X-Delta1 and regulates Notch signaling. Dev. Cell 1 795-806.
80. E.C. Lai, G. Deblandre and C. Kintner (2001) Drosophila Neuralized is a ubiquitin ligase that interacts with X-Delta1 and regulates Notch signaling. Dev. Cell 1 795-806.
81. G. Wu, S. Lyapina, I. Das, J. Li, M. Gurney, A. Pauley, I. Chui, R.J. Deshaies and J. Kitajewski (2001) SEL-10 is an inhibitor of Notch signaling that targets Notch for ubiquitin-mediated protein degradation. Mol. Cell Biol. 7403-7415.
82. C.J.L. Oberg, J. Li, A. Pauley, E. Wolf, M. Gurney and U. Lendahl (2001) The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog. J. Biol. Chem. 276 35847-35853.
83. L. Qiu, C. Joazeiro, N. Fang, H.-Y. Wang, C. Elly, Y. Altman, D. Fang, T. Hunter and Y.-C. Liu (2000) Recognition and ubiquitination of Notch by Itch, a Hect-type E3 ubiquitin ligase. J. Biol. Chem. 46 35734-35737.
84. E. Lai (2002) Protein degradation: Four E3s for the Notch pathway. Curr. Biol. 12 R74-R78.
85. F. Schweisguth (1999) Dominant-negative mutation in the beta2 and beta6 proteasone subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage. Proc. Natl. Acad. Sci. USA 96 11382-11386.
86. E.J. Hubbard, G. Wu, J. Kitajewski and I. Greenwald (1997) sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev. 11 3182-3193.
87. M. Fostier, D.A. Evans, S. Artavanis-Tsakonas and M. Baron (1998) Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of notch signaling. Genetics 150 1477-1485.
88. C.M. Hustad, W.L. Perry, L.D. Siracusa, C. Rasberry, L. Cobb, B.M. Cattanach, R. Kovatch, N.G. Copeland and N.A. Jenkins (1995) Molecular genetic characterization of six recessive viable alleles of the mouse agouti locus. Genetics 140 255-265.
89. D. Fang, C. Elly, B. Gao, N. Fang, Y. Altman, C. Joazeiro, T. Hunter, N. Copeland, N. Jenkins and Y.-C. Liu (2002) Dysregulation of T lymphocyte function in itchy mice: A role for Itch in TH2 differentiation. Nature Immunol.
90. M. Furriols and S. Bray (2001) A model Notch response element detects Suppressor of Hairless-dependent molecular switch. Curr. Biol. 11 60-64.
91. Y. Li and N.E. Baker (2001) Proneural enhancement by Notch overcomes Suppressor-of-Hairless repressor function in the developing Drosophila eye. Curr. Biol. 11 330-338.
92. K.A. Guss, C.E. Nelson, A. Hudson, M.E. Kraus and S.B. Carroll (2001) Control of a genetic regulatory network by a selector gene. Science 292 1164-1167.
93. E. Knust, H. Schrons, F. Grawe and J.A. Campos-Ortega (1992) Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics 132 505-518.
94. M.T.D. Cooper, D.M. Tyler, M. Furriols, A. Chaldiadaki, C. Delidakis and S. Bray (2000) Spatially restricted factors cooperate with Notch in the regulation of Enhancer of split genes. Dev. Biol. 221 390-403.
95. A. Singson, M. Leviten, A. Bang, X.H. Hua and J.W. Posakony (1994) Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling. Genes Dev. 8 2058-2071.
96. J. Cowden and M. Levine (2002) The Snail repressor positions Notch signaling in the Drosophila embryo. Development 129 1785-1793.
97. S.E. Cole, J.M. Levorse, S.M. Tilghman and T.F. Vogt (2002) Clock regulatory elements control cyclic expression of Lunatic fringe during somitogenesis. Dev. Cell 3 75-84.
98. A.V. Morales, Y. Yasuda and D. Ish-Horowicz (2002) Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to Notch signaling. Dev. Cell 3 63-74.
99. C. Klambt, E. Knust, K. Tietze and J. Campos-Ortega (1989) Closely related transcripts encoded by the neurogenic gene complex Enhancer of split of Drosophila melanogaster. EMBO J. 8 203-210.
100. M. Rohrbaugh, E. Ramos, D. Nguyen, M. Price, Y. Wen and Z.-C. Lai (2002) Notch activation of yan expression is antagonized by RTK/Pointed signaling in the Drosophila eye. Curr. Biol. 12 576-581.
101. B. Reizis and P. Leder (2002) Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway. Genes Dev. 16 292-300.
102. K. Takebayashi, Y. Sasai, Y. Sakai, T. Watanabe, S. Nakanishi and R. Kageyama (1994) Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. J. Biol. Chem. 269 5150-5156.
103. K. Takebayashi, C. Akazawa, S. Nakanishi and R. Kageyama (1995) Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5. J. Biol. Chem. 270 1342-1349.
104. Y. Bessho, G. Miyoshi, R. Sakata and R. Kageyama (2001) Hes7: A bHLH type repressor gene regulated by Notch and expressed in the presomitic mesoderm. Genes Cells 6 175-185.
105. T. Iso, G. Chung, Y. Hamamori and L. Kedes (2002) HERP1 is a cell type-specific primary target of Notch. J. Biol. Chem. 277 6598-6607.
106. O. Nakagawa, D.G. McFadden, M. Nakagawa, H. Yanagisawa, T. Hu, D. Srivastava and E.N. Olson (2000) Members of the HRT family of basic-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. Proc. Natl. Acad. Sci. USA 97 13655-13660.
107. M. Maier and M. Gessler (2000) Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes. Biochem. Biophys. Res. Commun. 275 652-660.
108. F. Oswald, S. Liptay, G. Adler and R.M. Schmid (1998) NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa. Mol. Cell Biol. 18 2077-2088.
109. Y. Chen, W.H. Fischer and G.N. Gill (1997) Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH. J. Biol. Chem. 272 14110-14114.
110. S. Plaisance, W. Vanden Berghe, E. Boone, W. Fiers and G. Haegeman (1997) Recombination signal sequence binding protein Jkappa is constitutively bound to the NF-kappaB site of the interleukin-6 promoter and acts as a negative regulatory factor. Mol. Cell Biol. 17 3733-3743.
111. C. Kannabiran, X. Zeng and L.D. Vales (1997) The mammalian transcriptional repressor RBP (CBF1) regulates interleukin-6 gene expression. Mol. Cell Biol. 17 1-9.
112. C. Ronchini and A.J. Capobianco (2001) Induction of cyclin D1 transcription and CDK2 activity by NotchicL: Implication for cell cycle diruption in transformation by Notchic. Mol. Cell Biol. 21 5925-5934.
113. I. Palmeirim, D. Henrique, D. Ish-Horowicz and O. Pourquie (1997) Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis. Cell 91 639-648.