An invitation to T and more: Notch signaling in lymphopoiesis

Cell

Volumn 109, Issue 2 SUPPL. 1, 2002, Pages S1-

  Allman, David ^a,c   Punt, Jennifer A ^d   Izon, David J ^a,b,c   Aster, Jon C ^e   Pear, Warren S ^a,b,c  

^a Department of Pathology and Laboratory Medicine ^*  (United States)

^b Institute for Medicine and Engineering   (United States)

^c HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^d HAVERFORD COLLEGE   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOTCH RECEPTOR;

CELL FATE; CELL LINEAGE; CELL MATURATION; HUMAN; LEUKEMOGENESIS; LYMPHOID CELL; LYMPHOPOIESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE;

METAZOA;

EID: 0036236895     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00689-X     Document Type: Review

References (82)

1. Positive and negative selection invoke distinct signaling pathways
2. Negative regulation of CD4 gene expression by a HES-1-c-Myb complex
3. Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells
4. Notch signaling in lymphocyte development
5. Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling
6. Notch signaling: Cell fate control and signal integration in development
7. Notch signaling in leukemia
8. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1
9. E2A deficiency leads to abnormalities in αβ T-cell development and to rapid development of T-cell lymphomas
10. A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiology
11. Rel/NF-κB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors
12. Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors
13. Notch inhibition of Ras signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development
14. Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells
15. Notch pathway: Making sense of Suppressor of Hairless
16. Ligand-induced signaling in the absence of furin processing of Notch1
17. Notch-1 regulates NF-κB activity in hemopoietic progenitor cells
18. Notch signaling in T cell development
19. Correlating notch signaling with thymocyte maturation
20. Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
21. Presenilin-dependent γ-secretase activity modulates thymocyte development
22. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
23. SEL-5, a serine/threonine kinase that facilitates lin-12 activity in Caenorhabditis elegans
24. Groucho proteins: Transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates
25. LIN-12/Notch signaling: Lessons from worms and flies
26. γ-secretase inhibitors repress thymocyte development
27. Modulated expression of notch1 during thymocyte development
28. NF-κB is required for the positive selection of CD8+ thymocytes
29. Signal strength in thymic selection and lineage commitment
30. Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells
31. Sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
32. Retroviral transduction of enriched hematopoietic stem cells allows lifelong Bcl-2 expression in multiple lineages but does not perturb hematopoiesis
33. Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength
34. Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1
35. Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation
36. Protective effects of notch-1 on TCR-induced apoptosis
37. Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice
38. Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wing
39. A role for pref-1 and HES-1 in thymocyte development
40. The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells
41. Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1
42. Lymphocyte development from hematopoietic stem cells
43. A common enzyme connects notch signaling and Alzheimer's disease
44. Neuralized: Regulating notch by putting away delta
45. Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5
46. Inducible expression of a p56Lck transgene reveals a central role for Lck in the differentiation of CD4 SP thymocytes
47. Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma
48. No requirement for V(D)J recombination in p53-deficient thymic lymphoma
49. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
50. Local induction of patterning and programmed cell death in the developing Drosophila retina
51. Notch as a mediator of cell fate determination in hematopoiesis: Evidence and speculation
52. Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
53. Character changes caused by mutation of an entire region of a chromosome in Drosophila
54. Fringe is a glycosyltransferase that modifies Notch
55. Cell cycle arrest and apoptosis induced by notch1 in B cells
56. Notch signaling suppresses IgH gene expression in chicken B cells: Implication in spatially restricted expression of Serrate2/Notch1 in the bursa of Fabricius
57. LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation
58. Notch and the immune system
59. Fringe modulates Notch-ligand interactions
60. Notch1 expression in early lymphopoiesis influences B versus T lineage determination
61. Deficient T cell fate specification in mice with an induced inactivation of Notch1
62. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
63. Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway
64. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
65. Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic)
66. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling
67. Introduction: Notch signalling and choice of cell fates in development
68. Activated notch1 modulates gene expression in B cells similarly to Epstein-Barr viral nuclear antigen 2
69. The bHLH gene Hes1 is essential for expansion of early T cell precursors
70. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells
71. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive notch1 signaling
72. NF-κB activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development
73. Human Notch-1 inhibits NF-κB activity in the nucleus through a direct interaction involving a novel domain
74. Notch activity influences the αβ versus γδ T cell lineage decision
75. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus
76. Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros
77. Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development
78. SEL-10 is an inhibitor of Notch signaling that targets Notch for ubiquitin-mediated protein degradation
79. The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate
80. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing
81. An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila
82. EBNA2 and Notch signalling in Epstein-Barr virus mediated immortalization of B lymphocytes