Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate

Current Biology

Volumn 11, Issue 22, 2001, Pages 1729-1738

  Ramain, Philippe ^a   Khechumian, Konstantin ^a   Seugnet, Laurent ^b   Arbogast, Nadine ^a   Ackermann, Claudine ^a   Heitzler, Pascal ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; DROSOPHILA; HEXAPODA; INSECTA;

EID: 0035856467     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00562-0     Document Type: Article

References (61)

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4. Development of adult sensilla on the wing and notum of Drosophila melanogaster
5. The achaetae-scute gene complex of Drosophila melanogaster: Conserved domains in a subset of genes required for neurogenesis and their homology to myc
6. Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc
7. Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing
8. On the phenotype and development of mutants of early neurogenesis in Drosophila melanogaster
9. The expression of neurogenic loci in the imaginal epidermal cells of Drosophila melanogaster
10. The choice of cell fate in the epidermis of Drosophila
11. Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins
12. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
13. Single amino-acid substitutions in EGF-like elements of Notch and Delta modify Drosophila development and affect cell-adhesion in vitro
14. Glycosyltreansferase activity of Fringe modulates Notch-Delta interactions
15. Fringe is a glycosyltransferase that modifies Notch
16. The Notch signaling regulator Fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DxD
17. Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J-k/Su(H)
18. The Suppressor of Hairless protein participates in Notch receptor signaling
19. Suppressor-of-Hairless is required for signal reception during lateral inhibition in the Drosophila pupal notum
20. Notch signaling: From the outside in
21. Suppressor of Hairless directly activates transcription of Enhancer of split complex genes in response to Notch receptor activity
22. The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split complex genes triggered by Notch signalling
23. Interaction between Wingless and Notch signaling pathways mediated by dishevelled
24. Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions
25. Genetic analysis of the hairy locus in Drosophila melanogaster
26. Genes of the Enhancer of split and achaete scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila
27. Extramacrochaetae, a transacting gene of the achaete-scute complex of Drosophila involved in cell communication
28. The Drosophila neurogenic gene neuralised encodes a novel protein and is expressed in precursors of larval and adult neurons
29. Revisiting the Drosophila microchaetae lineage: A novel intrinsically asymmetric cell division generates a glial cell
30. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
31. A functional analysis of Notch mutations in Drosophila
32. Wingless modulates the effects of dominant negative Notch molecules in the developing wing of Drosophila
33. The Abruptex mutations of Notch disrupt the establishment of proneural clusters in Drosophila
34. Repression by Notch is required before Wingless signaling during muscle progenitor cell development in Drosophila
35. Notch inhibition of E47 supports the existence of a novel signaling pathway
36. Evidence for a novel Notch pathway required for muscle precursor selection in Drosophila
37. Cytosolic interaction between deltex and Notch ankyrin repeats implicated deltex in the Notch signalling pathway
38. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
39. Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila
40. A genetic analysis of deltex and its interaction with the Notch locus in Drosophila melanogaster
41. Wnt signaling: A common theme in animal development
42. Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch
43. Two different activities of Suppressor of Hairless during wing development in Drosophila
44. Human deltex is a conserved regulator of Notch signaling
45. A role for CKII phosphorylation of the Cactus PEST domain in dorsoventral patterning of the Drosophila embryo
46. Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos
47. Dominant-negative mutation in the β2 and β6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage
48. The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase
49. Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
50. An activity of Notch regulates JNK signaling and affects dorsal closure in Drosophila
51. Negative regulation of JUN/AP1: Conserved function of glycogen synthase kinase 3 and the Drosophila kinase Shaggy
52. The Dishevelled protein is modified by Wingless signaling in Drosophila
53. Diverse roles for the Notch receptor in the development of D. melanogaster
54. Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules
55. Transcriptional repression by Suppressor of Hairless involves the binding of a Hairless-dCtBP complex in Drosophila
56. A model Notch response element detects Suppressor of Hairless-dependent molecular switch
57. Neuroectodermal transcription of the Drosophila neurogenic genes E(spl) and HLH-m5 is regulated by proneural genes
58. Lateral inhibition mediated by the Drosophila neurogenic gene Delta is enhanced by proneural proteins
59. Notch and wingless regulate expression of cuticle patterning genes
60. Fringe forms a complex with Notch
61. Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis