Variations on the Notch pathway in neural development

Current Opinion in Neurobiology

Volumn 12, Issue 1, 2002, Pages 64-70

  Justice, Nicholas J ^a   Jan, Yuh Nung ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGASE; NOTCH RECEPTOR; PROTEASOME; UBIQUITIN;

CELL FATE; GLIA CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION;

EID: 0036471938     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(02)00291-X     Document Type: Review

References (55)

1. Notch signaling: Cell fate control and signal integration in development
2. Notch and presenilin: A proteolytic mechanism emerges
3. Notch pathway: Making sense of suppressor of hairless
4. Neuralized functions as an E3 ubiquitin ligase during Drosophila development
5. sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
6. The lore of the RINGs: Substrate recognition and catalysis by ubiquitin ligases
7. The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
8. Functional interaction between Sel-10, an F-box protein, and the nuclear form of activated Notch1 receptor
9. Sel-10 is an inhibitor of Notch signaling that targets Notch for ubiquitin-mediated protein degradation
10. Recognition and ubiquitination of Notch by Itch, a HECT-type E3 ubiquitin ligase
11. The Drosophila melanogaster suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase
12. Neuralized functions cell-autonomously to regulate a subset of Notch-dependent processes during adult Drosophila development
13. Neuralized functions cell autonomously to regulate Drosophila sense organ development
14. Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing
15. Membrane-bound transcription factors: Regulated release by RIP or RUP
16. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
17. Notch signaling: Fringe really is a glycosyltransferase
18. Scabrous complexes with Notch to mediate boundary formation
19. Glycosyltransferase activity of Fringe modulates Notch-Delta interactions
20. Fringe is a glycosyltransferase that modifies Notch
21. Fringe, Notch, and making developmental boundaries
22. Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation
23. Fringe-dependent separation of dorsal and ventral cells in the Drosophila wing
24. Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation
25. Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2
26. Notch signaling in the development of the inner ear: Lessons from Drosophila
27. A mutation in the lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea
28. The Notch ligand Jagged1 is required for inner ear sensory development
29. The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
30. Spacing differentiation in the developing Drosophila eye: A fibrinogen-related lateral inhibitor encoded by Scabrous
31. Notch signaling in the nervous system. Pieces still missing from the puzzle
32. The Scabrous protein can act as an extracellular antagonist of Notch signaling in the Drosophila wing
33. Functional analysis of the fibrinogen-related scabrous gene from Drosophila melanogaster identifies potential effector and stimulatory protein domains
34. Delta and Serrate are redundant Notch ligands required for asymmetric cell divisions within the Drosophila sensory organ lineage
35. Up a Notch: Instructing gliogenesis
36. rax, Hes1, and notch1 promote the formation of Muller glia by postnatal retinal progenitor cells
37. Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells
38. Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate
39. Radial glial identity is promoted by Notch1 signaling in the murine forebrain
40. A unified hypothesis on the lineage of neural stem cells
41. The migrational patterns and developmental fates of glial precursors in the rat subventricular zone are temporally regulated
42. Radial glial cells: Are they really glial?
43. Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors
44. Cell cycle length of olfactory bulb neuronal progenitors in the rostral migratory stream
45. Revisiting the Drosophila microchaete lineage: A novel intrinsically asymmetric cell division generates a glial cell
46. Notch signaling represses the glial fate in fly PNS
47. A dual function of the Notch gene in Drosophila sensillum development
48. Notch1 inhibits neurite outgrowth in postmitotic primary neurons
49. The role of Notch and Rho GTPase signaling in the control of dendritic development
50. Contact-dependent inhibition of cortical neurite growth mediated by Notch signaling
51. IgCAMs: Bidirectional signals underlying neurite growth
52. Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease
53. neuralized encodes a peripheral membrane protein involved in delta signaling and endocytosis
54. Drosophila Neuralized is a ubiquitin ligase that promotes the internalization and degradation of Delta
55. Xenopus Neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling