The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIAA to prevent activated transcription

Genes and Development

Volumn 12, Issue 11, 1998, Pages 1621-1637

  Olave, Ivan ^a   Reinberg, Danny ^b   Vales, Lynne D ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

RBP; TFIIA ATTID targeting; Transcriptional repression

Indexed keywords

ANIMAL CELL; ARTICLE; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC TRANSCRIPTION; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALIA; MAMMALIA;

EID: 2642601104     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.11.1621     Document Type: Article

References (63)

1. Auble, D.T. and S. Hahn. 1993. An ATP-dependent inhibitor of TBP binding to DNA. Genes & Dev. 7: 844-856.
2. Babiss, L.E. and L.D. Vales. 1991. Promoter of the adenovirus polypeptide IX gene: Similarity to E1B and inactivation by substitution of the simian virus 40 TATA element. J. Virol. 65: 598-605.
3. Bailey, A.M. and J.W. Posakony. 1995. Suppressor of Hairless directly activates transcription of Enhancer of split Complex genes in response to Notch receptor activity. Genes & Dev. 9: 2609-2622.
4. Brou, C., F. Logeat, M. Lecourtois, J. Vandekerckhove, P. Kourilsky, F. Schweisguth, and A. Israel. 1994. Inhibition of the DNA-binding activity of Drosophila Suppressor of Hairless and its human homolog, KBF2/RBP-Jκ by direct protein-protein interaction with Drosophila Hairless. Genes & Dev. 8: 2491-2503.
5. Buratowski, S., S. Hahn, L. Guarentee, and P.A. Sharp. 1989. Five intermediate complexes in transcription initiation by RNA polymerase II. Cell 56: 549-561.
6. Burley, S.K. and R.G. Roeder. 1996. Biochemistry and structural biology of transcription factor IID (TFIID). Annu. Rev. Biochem. 65: 769-799.
7. Chi, T. and M. Carey. 1996. Assembly of the isomerized TFIIA-TFIID-TATA ternary complex is necessary and sufficient for gene activation. Genes & Dev. 10: 2540-2550.
8. Chi, T., P. Lieberman, K. Ellwood, and M. Carey. 1995. A general mechanism for transcriptional synergy by eukaryotic activators. Nature 377: 254-257.
9. Cortes, P., O. Flores, and D. Reinberg. 1992. Factors involved in specific transcription by mammalian RNA polymerase II: Purification and analysis of transcription factor IIA and identification of transcription factor IIJ. Mol. Cell. Biol. 12: 413-421.
10. Dou, S., X. Zeng, P. Cortes, H. Erdjument-Bromage, P. Tempst, T. Honjo, and L.D. Vales. 1994. The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor. Mol. Cell. Biol. 14: 3310-3319.
11. Eastman, D.S., R. Slee, E. Skoufos, L. Bangalore, S. Bray, and C. Delidakis. 1997. Synergy between Suppressor of Hairless and Notch in regulation of Enhancer of split mγ and mδ expression. Mol. Cell. Biol. 17: 5620-5628.
12. Fortini, M.E. and S. Artavanis-Tsakonas. 1994. The Suppressor of Hairless protein participates in Notch receptor signaling. Cell 79: 273-282.
13. Furukawa, T., S. Maruyama, M. Kawaichi, and T. Honjo. 1992. The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development. Cell 69: 1191-1197.
14. II110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc. Natl. Acad. Sci. 91: 192-196.
15. II40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB. Cell 75: 519-530.
16. Grossman, S.R., E. Johannsen, X. Tong, R. Yalamanchili, and E. Kieff. 1994. The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the Jκ recombination signal sequence binding protein. Proc. Natl. Acad. Sci. 91: 7568-7572.
17. Hamaguchi, Y., N. Matsunami, Y. Yamamoto, and T. Honjo. 1989. Purification and characterization of a protein that binds to the recombination signal sequence of the immunoglobulin Jκ segment. Nucleic Acids Res. 17: 9015-9026.
18. Hamaguchi, Y., Y. Yamamoto, H. Iwanari, S. Maruyama, T. Furukawa, N. Matsunami, and T. Honjo. 1992. Biochemical and immunological characterization of the DNA binding protein (RBP-Jκ) to mouse Jκ recombination signal sequence. J. Biochem. 112: 314-320.
19. Henkel, T., P.D. Ling, S.D. Hayward, and M.G. Peterson. 1994. Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein Jκ. Science 265: 92-95.
20. Herschbach, B.M. and A.D. Johnson. 1993. Transcriptional repression in eukaryotes. Annu. Rev. Cell Biol. 9: 479-509.
21. Hoey, T., R.O.J. Weinzierl, G. Gill, J.-L. Chen, B.D. Dynlacht, and R. Tjian. 1993. Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell 72: 247-260.
22. Hsieh, J.J.-D. and S.D. Hayward. 1995. Masking of the CBF1/ RBPJκ transcriptional repression domain by Epstein-Barr virus EBNA2. Science 268: 560-563.
23. Hsieh, J.J.-D., T. Henkel, P. Salmon, E. Robey, M.G. Peterson, and S.D. Hayward. 1996. Truncated mammalian Notch1 activates CBF1/RBPJκ-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16: 952-959.
24. Inostroza, J.A., F.H. Mermelstein, I. Ha, W.S. Lane, and D. Reinberg. 1992. Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription. Cell 70: 477-489.
25. Johnson A.D. 1995. The price of repression. Cell 81: 655-658.
26. Kannabiran, C., X. Zeng, and L.D. Vales. 1997. The mammalian transcriptional repressor RBP (CBF1) regulates interleukin-6 gene expression. Mol. Cell. Biol. 17: 1-9.
27. Kawaichi, M., C. Oka, S. Shibayama, A.E. Koromilas, N. Matsunami, Y. Hamaguchi, and T. Honjo. 1992. Genomic organization of mouse Jκ recombination signal binding protein (RBP-Jκ) gene. J. Biol Chem. 267: 4016-4022.
28. Kobayashi, N., T.G. Boyer, and A.J. Berk. 1995. A class of activation domains interacts directly with TFIIA and stimulates TFIIA-TFIID-promoter complex assembly. Mol. Cell. Biol. 15: 6465-6473.
29. Laux, G., B. Adam, L.J. Strobl, and F. Moreau-Gachelin. 1994. The Spi-1/PU.1 and Sp1-B ets family transcription factors and the recombination signal sequence binding protein RBP-Jκ interact with an Epstein-Barr virus nuclear antigen 2 responsive cis-element. EMBO J. 13: 5624-5632.
30. Lecourtois, M. and F. Schweisguth. 1995. The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of Split Complex genes triggered by Notch signaling. Genes & Dev. 9: 2598-2608.
31. Lee, D.K., J. DeJong, S. Hashimoto, M. Horikoshi, and R.G. Roeder. 1992. TFIIA induces conformational changes in TFIID via interactions with the basic repeat. Mol. Cell. Biol. 12: 5189-5196.
32. Lieberman, P.M. and A. Berk. 1994. A mechanism for TAFs in transcriptional activation: Activation domain enhancement of TFIID-TFIIA-promoter DNA complex formation. Genes & Dev. 8: 995-1006.
33. Lieberman, P.M., J. Ozer, and D.B. Gursel. 1997. Requirement for transcription factor HA (TFIIA)-TFIID recruitment by an activator depends on promoter structure and template competition. Mol. Cell. Biol. 17: 6624-6632.
34. Ma, D., I. Olave, A. Merino, and D. Reinberg. 1996. Separation of the transcriptional coactivator and antirepression function of transcription factor IIA. Proc. Natl. Acad. Sci. 93: 6583-6588.
35. Maldonado, E., I. Ha, P. Cortes, L. Weis, and D. Reinberg. 1990. Factors involved in specific transcription by mammalian RNA polymerase II: Role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex. Mol. Cell. Biol. 10: 6335-6347.
36. Matsunami, N., Y. Hamaguchi, Y. Yamamoto, K. Kuze, K. Kangawa, H. Matsuo, M. Kawaichi, and T. Honjo. 1989. A protein binding to the Jκ recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif. Nature 342: 934-937.
37. Meisterernst, M. and R.G. Roeder. 1991. Family of proteins that interact with TFIID and regulate promoter activity. Cell 67: 557-567.
38. Merino, A, K.R. Madden, W.S. Lane, J.J. Champoux, and D. Reinberg. 1994. DNA topoisomerase I is involved in both repression and activation of transcription. Nature 365: 227-232.
39. Nash, D. 1965. The expression of Hairless in Drosophila and the role of two closely linked modifiers of opposite effect. Genet. Res. 6: 175-189.
40. _. 1970. The mutational basis for the "allelic" modifier mutants, Enhancer and Suppressor of Hairless, of Drosophila melanogaster. Genetics 64: 471-479.
41. Oelgeschläger, T., C-M. Chiang, and R.G. Roeder. 1996. Topology and reorganization of a human TFIID-promoter complex. Nature 382: 735-738.
42. Oliner, J.D., J.A. Pietenpol, S. Thiagalingram, J. Gyuris, K.W. Kinzler, and B. Vogelstein. 1993. Oncoprotein MDM2 conceals the activation domain of tumor suppressor p53. Nature 364: 857-860.
43. Orphanides, G., T. Lagrange, and D. Reinberg. 1996. The general transcription factors of RNA polymerase II. Genes & Dev. 10: 2657-2683.
44. Oswald, F., S. Liptay, G. Adler, and R.M. Schmid. 1998. NF-κB2 is a putative target gene of activated Notch-1 via RBP-Jκ. Mol. Cell. Biol. 18: 2077-2088.
45. Plaisance, S., W.V. Berghe, E. Boone, W. Fiers, and G. Haegeman. 1997. Recombination signal sequence binding protein Jκ is constituitively bound to the NF-κB site of the interleukin-6 promoter and acts as a negative regulatory factor. Mol. Cell. Biol. 17: 3733-3743.
46. Robertson, E.S., J. Lin, and E. Kieff. 1996. The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJκ. J. Virol. 70: 3068-3074.
47. Roeder, R.G. 1996. The role of general initiation factors in transcription by RNA polymerase II. Trends Biochem. Sci. 21: 327-334.
48. Sauer, F., J.D. Fondell, Y. Ohkuma, R.G. Roeder, and H. Jackle. 1995. Control of transcription by Kruppel through interactions with TFIIB and TFIIEβ. Nature 375: 162-164.
49. Schweisguth, F. and J.W. Posakony. 1992. Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates. Cell 69: 1199-1212.
50. Sun, X., D. Ma, M. Sheldon, Y. Kam, and D. Reinberg. 1994. Reconstitution of human TFIIA activity from recombinant polypeptides: A role in TFIID-mediated transcription. Genes & Dev. 8: 2336-2348.
51. Taniguchi, Y., T. Furukawa, T. Tun, H. Han, and T. Honjo. 1998. LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein. Mol. Cell. Biol. 18: 644-654.
52. Thut, C.J., J.A. Goodrich, and R. Tjian. 1997. Repression of p53-mediated transcription by MDM2: A dual mechanism. Genes &. Dev. 11: 1974-1986.
53. Tun, T., Y. Hamaguchi, N. Matsunami, T. Furukawa, T. Honjo, and M. Kawaichi. 1994. Recognition sequence of a highly conserved DNA binding protein RBP-Jκ. Nucleic Acids Res. 22: 965-971.
54. Van Dyke, M.W., R.G. Roeder, and M. Sawadogo. 1988. Physical analysis of transcription preinitiation complex formation on class II gene promoter. Science 241: 1335-1338.
55. Waltzer, L., F. Logeat, C. Brou, A. Israel, A. Sergeant, and E. Manet. 1994. The human Jκ recombination signal sequence binding protein (RBP-Jκ) targets the Epstein-Barr virus EBNA2 protein to its DNA responsive elements. EMBO J. 13: 5633-5638.
56. Weintraub, S.J., K.N.B. Chow, R.X. Luo, S.H. Zhang, S. He, and D.C. Dean. 1995. Mechanism of active transcriptional repression by the retinoblastoma protein. Nature 375: 812-815.
57. Wu, G.D., E.J. Lai, N. Huang, and X. Wen. 1997. Oct-1 and CCAAT/Enhancer binding protein (C/EBP) bind to overlapping elements within the interleukin-8 promoter. J. Biol. Chem. 272: 2396-2403.
58. Wu, L. and A. Berk. 1988. Constraints on spacing between transcription factor binding sites in a simple adenovirus promoter. Genes & Dev. 2: 403-411.
59. Yeung, K.C., J.A. Inostroza, F.H. Mermelstein, C. Kannabiran, and D. Reinberg. 1994. Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription. Genes & Dev. 8: 2097-2109.
60. Yokomori, K., A. Admon, J.A. Goodrich, J.-L. Chen, and R. Tjian. 1993. Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex. Genes & Dev. 7: 2235-2245.
61. Zawel, L., P.K. Kumar, and D. Reinberg. 1995. Recycling of the general transcription factors during RNA polymerase II transcription. Genes & Dev. 9: 1479-1490.
62. Zhou, Q., P.M. Lieberman, T.G. Boyer, and A.J. Berk. 1992. Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter. Genes & Dev. 6: 1964-1974.
63. Zimber-Strobl, U., L.J. Strobl, C. Meitinger, R. Hinrichs, T. Sakai, T. Furukawa, T. Honjo, and G.W. Bornkamm. 1994. Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-Jκ, the homologue of Drosophila Suppressor of Hairless. EMBO J. 13: 4973-4982.