Notch activation of yan expression is antagonized by RTK/pointed signaling in the Drosophila eye

Current Biology

Volumn 12, Issue 7, 2002, Pages 576-581

  Rohrbaugh, Margaret ^a   Ramos, Edward ^b   Nguyen, Duc ^b   Price, Mitch ^b   Wen, Yu ^b   Lai, Zhi Chun ^a,b  

^a Department of Biochemistry and Molecular Biology ^*  (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEXAPODA; INSECTA;

ANTERIOR OPEN PROTEIN, DROSOPHILA; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; EYE PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; NOTCH PROTEIN, DROSOPHILA; NOTCH RECEPTOR; ONCOPROTEIN; PNT PROTEIN, DROSOPHILA; PROTEIN; PROTEIN TYROSINE KINASE; REPRESSOR PROTEIN; SUPPRESSOR OF HAIRLESS PROTEIN, DROSOPHILA; TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; DROSOPHILA MELANOGASTER; ENHANCER REGION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENHANCER ELEMENTS (GENETICS); EYE PROTEINS; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 0037006801     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00743-1     Document Type: Article

References (35)

1. Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein
2. Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway in Drosophila
3. Notch signaling: Cell fate control and signal integration in development
4. Notch signaling: From the outside in
5. Notch pathway: Making sense of Suppressor of Hairless
6. A model Notch response element detects Suppressor of Hairless-dependent molecular switch
7. Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: The E(spl) genes mediate only a subset of Notch activities during imaginal development
8. Evolution of proneural atonal expression during distinct regulatory phases in the developing Drosophila eye
9. Basic helix-loop-helix genes in neural development
10. Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer
11. Combinatorial signaling in the specification of unique cell fates
12. The ets gene family
13. The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway
14. The ETS domain protein Pointed-P2 is a target of MAP kinase in the Sevenless signal transduction pathway
15. Ras promotes cell survival in Drosophila by downregulating hid expression
16. Interaction of short range repressors with Drosophila CtBP in the embryo
17. Drosophila CtBP: A Hairy-interacting protein required for embryonic segmentation and Hairy-mediated transcriptional repression
18. Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development
19. Vectors for Drosophila P-element-mediated transformation and tissue culture transfection
20. Genetic transformation of Drosophila with transposable element vectors
21. Repression by Suppressor of Hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryos
22. Patterning of cells in the developing Drosophila eye by Lozenge, which shares homologous domains with AML1
23. Dissecting the mechanisms of Suppressor of Hairless function
24. A subset of Notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex
25. Multiple functions of the EGF receptor in Drosophila eye development
26. Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues
27. The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS
28. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye
29. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
30. Analysis of genetic mosaics in developing and adult Drosophila tissues
31. Characterization and spatial distribution of the ELAV protein during Drosophila melanogaster development
32. Suppressor of Hairless directly activates transcription of Enhancer of split complex genes in response to Notch receptor activity
33. The Drosophila homolog of Onecut homeodomain proteins is a neural-specific transcriptional activator with a potential role in regulating neural differentiation
34. Ras1 signaling and transcriptional competence in the R7 cell of Drosophila