The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the Notch signaling pathway

Developmental Biology

Volumn 238, Issue 1, 2001, Pages 110-119

  Krebs, Luke T ^a   Deftos, Michael L ^b   Bevan, Michael J ^b   Gridley, Thomas ^a  

^a JACKSON LABORATORY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Ankyrin repeat; Downstream target gene; Notch signaling pathway

Indexed keywords

ANKYRIN; NOTCH RECEPTOR; PROTEIN NRARP; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CONSENSUS SEQUENCE; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; EVOLUTION; GENE EXPRESSION; GENETIC ANALYSIS; IN SITU HYBRIDIZATION; MESODERM; MOUSE; NEURAL TUBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SOMITE; TRANSCRIPTION REGULATION;

EID: 0035476460     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0408     Document Type: Article

References (50)

1. Notch signaling: Cell fate control and signal integration in development
2. Dynamic expression of lunatic fringe suggests a link between notch signaling and an autonomous cellular oscillator driving somite segmentation
3. The inhibitor of DNA replication encoded by the Drosophila gene p lutonium is a small, ankyrin repeat protein
4. Notch signaling in T cell development
5. Correlating notch signaling with thymocyte maturation
6. Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
7. Drosophila PLUTONIUM protein is a specialized cell cycle regulator required at the onset of embryogenesis
8. PAN GU: A protein kinase that inhibits S phase and promotes mitosis in early Drosophila development
9. Waves of mouse Lunatic fringe expression, in four-hour cycles at two-hour intervals, precede somite boundary formation
10. Expression of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development
11. Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning
12. Maintenance of somite borders in mice requires the Delta homologue Dll1
13. Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2
14. Identifying differences in mRNA expression by representational difference analysis of cDNA
15. Signaling downstream of activated mammalian Notch
16. The Slug gene is not essential for mesoderm or neural crest development in mice
17. Notch signaling: A dance of proteins changing partners
18. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway
19. Identification and expression of a novel family of bHLH cDNAs related to Drosophila hairy and Enhancer of split
20. Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis
21. The mouse pudgy mutation disrupts Delta homologue D113 and initiation of early somite boundaries
22. Identity of the beta-globin locus control region binding protein HS2NF5 as the mammalian homolog of the notch-regulated transcription factor suppressor of hairless
23. Hey genes: A novel subfamily of hairy- and Enhancer of split-related genes specifically expressed during mouse embryogenesis
24. A subset of notch functions during Drosophila eye development require Su(H) and the E(sp1) gene complex
25. Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes
26. Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system
27. A molecular clock involved in somite segmentation
28. Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements
29. The lunatic fringe gene is a target of the molecular clock linked to somite segmentation in avian embryos
30. Mouse Serrate-1 (Jagged-1): Expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4
31. Notch signaling: From the outside in
32. Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of notch signaling
33. HRT1, HRT2, and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments
34. A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral column, kidney and nervous system
35. Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split
36. Notch signaling imposes two distinct blacks in the differentiation of C2C12 myoblasts
37. NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa
38. Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis
39. Evidence for a novel Notch pathway required for muscle precursor selection in Drosophila
40. Mesp2: A novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation
41. The ankyrin repeat: A diversity of interactions on a common structural framework
42. The Drosophila plutonium and pan gu genes regulate entry into S phase at fertilization
43. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
44. Notch1 is essential for postimplantation development in mice
45. Mesp2 initiates somite segmentation through the Notch signalling pathway
46. Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)
47. Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless
48. Notch signal transduction: A real Rip and more
49. An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila
50. Defects in somite formation in Lunatic fringe deficient mice