Repression by Suppressor of Hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo

Genes and Development

Volumn 14, Issue 3, 2000, Pages 377-388

  Morel, Véronique ^a   Schweisguth, François ^a  

^a ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

Dorsoventral axis; Notch; Sim; Su(H); Transcription

Indexed keywords

ANIMAL CELL; ARTICLE; BINDING SITE; BLASTODERM; CONTROLLED STUDY; DNA BINDING; DROSOPHILA; EMBRYO DEVELOPMENT; GENE ACTIVATION; GENE REPRESSION; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; BLOTTING, SOUTHERN; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM LAYERS; IN SITU HYBRIDIZATION; MEMBRANE PROTEINS; NUCLEAR PROTEINS; PROTEIN BINDING; RECEPTORS, NOTCH; REGULATORY SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION;

ANIMALIA; HEXAPODA;

EID: 0034142323     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Artavanis-Tsakonas, S., M.D. Rand, and R.J. Lake. 1999. Notch signaling: Cell fate control and signal integration in development. Science 284: 770-776.
2. Bailey, A.M. and J.W. Posakony. 1995. Suppressor of Hairless directly activates transcription of Enhancer of split complex genes in response to Notch receptor activity. Genes & Dev. 9: 2609-2622.
3. Brou, C., F. Logeat, M. Lecourtois, J. Vandekerckhove, P. Kourilsky, F. Schweisguth, and A. Israel. 1994. Inhibition of the DNA-binding activity of Drosophila Suppressor of Hairless and of its human homolog, KBF2/RBP-J κ, by direct proteinprotein interaction with Drosophila hairless. Genes & Dev. 8: 2491-2503.
4. Campos-Ortega, J.A. and V. Hartenstein. 1997. The embryonic development of Drosophila melanogaster. Springer, Berlin, Germany.
5. Chou, T.-B. and N. Perrimon. 1996. The autosomal FLP-DFS technique for generating germ-line mosaics in Drosophila melanogaster. Genetics 144: 1673-1679.
6. Crews, S.T. 1998. Control of cell lineage-specific development and transcription by bHLH-PAS proteins. Genes & Dev. 12: 607-620.
7. Crews, S.T., J.B. Thomas, and C.S. Goodman. 1988. The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product. Cell 52: 143-151.
8. Dou, S., X. Zeng, P. Cortes, H. Erdjument-Bromage, P. Tempst, T. Honjo, and L.D. Vales. 1994. The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor. Mol. Cell. Biol. 14: 3310-3319.
9. Fehon, R.G., K. Johansen, I. Rebay, and S. Artavanis-Tsakonas. 1991. Complex cellular and subcellular regulation of Notch expression during embryonic and imaginal development of Drosophila: Implications for Notch function. J. Cell Biol. 113: 657-669.
10. Hacker, U. and N. Perrimon. 1998. DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during Drosophila gastrulation. Genes & Dev. 12: 274-284.
11. Henkel, T., P.D. Ling, S.D. Hayward, and M.G. Peterson. 1994. Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa. Science 265: 92-95.
12. Hsieh, J.J., T. Henkel, P. Salmon, E. Robey, M.G. Peterson, and S.D. Hayward. 1996. Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16: 952-959.
13. Hsieh, J.J., S. Zhou, L. Chen, D.B. Young, and S.D. Hayward. 1999. CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. Proc. Natl. Acad. Sci. 96: 23-28.
14. Ip, Y.T., R.E. Park, D. Kosman, K. Yazdanbakhsh, and M. Levine. 1992. Dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo. Genes & Dev. 6: 1518-1530.
15. Jarriault, S., C. Brou, F. Logeat, E.H. Schroeter, R. Kopan, and A. Israel. 1995. Signalling downstream of activated mammalian Notch. Nature 377: 355-358.
16. Kao, H.Y., P. Ordentlich, N. Koyano-Nakagawa, Z. Tang, M. Downes, C.R. Kintner, R.M. Evans, and T. Kadesch. 1998. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes & Dev. 12: 2269-2277.
17. Kasai, Y., J.R. Nambu, P.M. Lieberman, and S.T. Crews. 1992. Dorsal-ventral patterning in Drosophila: DNA binding of Snail protein to the single-minded gene. Proc. Natl. Acad. Sci. 89: 3414-3418.
18. Kasai, Y., S. Stahl, and S. Crews. 1998. Specification of the Drosophila CNS midline cell lineage: Direct control of single-minded transcription by dorsal/ventral patterning genes. Gene Expr. 7: 171-189.
19. Kidd, S., T. Lieber, and M.W. Young. 1998. Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. Genes & Dev. 12: 3728-3740.
20. Klambt, C., J.R. Jacobs, and C.S. Goodman. 1991. The midline of the Drosophila central nervous system: A model for the genetic analysis of cell fate, cell migration, and growth cone guidance. Cell 64: 801-815.
21. Kooh, P.J., R.G. Fehon, and M.A. Muskavitch. 1993. Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 117: 493-507.
22. Kosman, D., Y.T. Ip, M. Levine, and K. Arora. 1991. Establishment of the mesoderm-neuroectoderm boundary in the Drosophila embryo. Science 254: 118-122.
23. Kunkel, T.A. 1985. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. 82: 488-492.
24. Lecourtois, M. and F. Schweisguth. 1995. The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split complex genes triggered by Notch signaling. Genes & Dev. 9: 2598-2608.
25. _. 1998. Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos. Curr. Biol. 8: 771-774.
26. Leptin, M. 1991. Twist and Snail as positive and negative regulators during Drosophila mesoderm development. Genes & Dev. 5: 1568-1576.
27. Leptin, M. and S. Roth. 1994. Autonomy and non-autonomy in Drosophila mesoderm determination and morphogenesis. Development 120: 853-859.
28. Lieber, T., S. Kidd, E. Alcamo, V. Corbin, and M.W. Young. 1993. Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes & Dev. 7: 1949-1965.
29. Martin-Bermudo, M.D., A. Carmena, and F. Jimenez. 1995. Neurogenic genes control gene expression at the transcriptional level in early neurogenesis and in mesectoderm specification. Development 121: 219-224.
30. Menne, T.V. and C. Klambt. 1994. The formation of commissures in the Drosophila CNS depends on the midline cells and on the Notch gene. Development 120: 123-133.
31. Muralidhar, M.G., C.A. Callahan, and J.B. Thomas. 1993. Single-minded regulation of genes in the embryonic midline of the Drosophila central nervous system. Mech. Dev. 41: 129-138.
32. Nambu, J.R., R.G. Franks, S. Hu, and S.T. Crews. 1990. The single-minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells. Cell 63: 63-75.
33. Nambu, J.R., J.O. Lewis, K.A. Wharton Jr., and S.T. Crews. 1991. The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development. Cell 67: 1157-1167.
34. Nellesen, D.T., E.C. Lai, and J.W. Posakony. 1999. Discrete enhnacer elements mediate selective responsiveness of Enhancer of split complex genes to common transcriptional activators. Dev. Biol. 213: 33-53.
35. Rusch, J. and M. Levine. 1996. Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo. Curr. Opin. Genet. Dev. 6: 416-423.
36. Schroeter, E.H., J.A. Kisslinger, and R. Kopan. 1998. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393: 382-386.
37. Schweisguth, F. and J.W. Posakony. 1992. Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates. Cell 69: 1199-1212.
38. St. Johnston, D. and C. Nüsslein-Volhard. 1992. The origin of pattern and polarity in the Drosophila embryo. Cell 68: 201-219.
39. Struhl, G. and A. Adachi. 1998. Nuclear access and action of Notch in vivo. Cell 93: 649-660.
40. Thomas, J.B., S.T. Crews, and C.S. Goodman. 1988. Molecular genetics of the single-minded locus: A gene involved in the development of the Drosophila nervous system. Cell 52: 133-141.
41. Thummel, C.S., A.M. Boulet, and H.D. Lipshitz. 1988. Vectors for Drosophila P-element-mediated transformation and tissue culture transfection, Gene 74: 445-456.
42. Tun, T., Y. Hamaguchi, N. Matsunami, T. Furukawa, T. Honjo, and M. Kawaichi. 1994. Recognition sequence of a highly conserved DNA binding protein RBP-J kappa. Nucleic Acids Res. 22: 965-971.
43. Wharton, K.A. Jr., R.G. Franks, Y. Kasai, and S.T. Crews. 1994. Control of CNS midline transcription by asymmetric E-box-like elements: Similarity to xenobiotic responsive regulation. Development 120: 3563-3569.
44. Zecchini, V., K. Brennan, and A. Martinez-Arias. 1999. An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila. Curr. Biol. 9: 460-469.