Anti-cancer drugs: Molecular mechanisms of action

Mini-Reviews in Medicinal Chemistry

Volumn 5, Issue 7, 2005, Pages 685-695

  Isoldi, Mauro Cesar ^a   Visconti, Maria Aparecida ^b   de Lauro Castrucci, Ana Maria ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cancer; Cell signaling; Mechanisms of action; p53; Ras protein

Indexed keywords

2 [[2 [[2 [(2 AMINO 3 MERCAPTOPROPYL)AMINO] 3 METHYLPENTYL]OXY] 1 OXO 3 PHENYLPROPYL]AMINO] 4 (METHYLSULFONYL)BUTANOIC ACID ISOPROPYL ESTER; AMSACRINE DERIVATIVE; ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; ARF PROTEIN; BRYOSTATIN; CAMPTOTHECIN DERIVATIVE; CYTOSTATIC AGENT; DIMINAZENE ACETURATE; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; EPIPODOPHYLLOTOXIN DERIVATIVE; ETHIDIUM BROMIDE; L 778123; LONAFARNIB; MITOGEN ACTIVATED PROTEIN KINASE; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PEPTIDE DERIVATIVE; PROTEIN BCL 2; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN INHIBITOR; PROTEIN P53; RAF PROTEIN; RAS PROTEIN; TIPIFARNIB;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER; CANCER CONTROL; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL TRIAL; COLORECTAL CARCINOMA; DNA DAMAGE; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; GENE MUTATION; GENETIC ANALYSIS; HEMATOLOGIC MALIGNANCY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LUNG CARCINOMA; MULTIDRUG RESISTANCE; NONHUMAN; PANCREAS CARCINOMA; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; TREATMENT FAILURE;

ALKYL AND ARYL TRANSFERASES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIVISION; ENZYME INHIBITORS; HUMANS; INTRACELLULAR SPACE; NEOPLASMS; RAS PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 21644450020     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557054368781     Document Type: Review

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