The channel of death

Journal of Cell Biology

Volumn 155, Issue 5, 2001, Pages 695-697

  Degterev, Alexei ^a   Boyce, Michael ^a   Yuan, Junying ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYTOCHROME C; INTERLEUKIN 3; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; CELL DEATH; ENZYME ACTIVATION; LIPID BILAYER; MEMBRANE CONDUCTANCE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SHORT SURVEY;

ANIMALS; APOPTOSIS; INTRACELLULAR MEMBRANES; ION CHANNELS; MITOCHONDRIA; MODELS, BIOLOGICAL; PROTO-ONCOGENE PROTEINS C-BCL-2;

ANIMALIA;

EID: 0035956436     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200110147     Document Type: Short Survey

References (19)

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3. The apoptosome: Heart and soul of the cell death machine
4. VDAC, a channel in the outer mitochondrial membrane
5. Bcl-2 family members and the mitochondria in apoptosis
6. The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability
7. Tom4O forms the hydrophilic channel of the mitochondrial import pore for preproteins
8. 'What nourishes me, destroys me': Towards a new mitochondrial biology
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10. Endonuclease G is an apoptotic DNase when released from mitochondria
11. A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast
12. BAX-dependent transport of cytochrome c reconstituted in pure liposomes
13. Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c
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15. Structure of Bax: Coregulation of dimer formation and intracellular localization
16. VDAC regulation by the Bcl-2 family of proteins
17. Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process
18. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
19. The mitochondrion in apoptosis: How Pandora's box opens