메뉴 건너뛰기




Volumn 12, Issue 19, 1998, Pages 2984-2991

Tumor surveillance via the ARF-p53 pathway

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 0032191393     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.19.2984     Document Type: Review
Times cited : (670)

References (82)
  • 1
    • 0025937489 scopus 로고
    • Constitutive c-myc expression in an IL3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
    • Askew, D.S., R.A. Ashmun, B.C. Simmons, and J.L. Cleveland. 1991. Constitutive c-myc expression in an IL3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene 6: 1915-1922.
    • (1991) Oncogene , vol.6 , pp. 1915-1922
    • Askew, D.S.1    Ashmun, R.A.2    Simmons, B.C.3    Cleveland, J.L.4
  • 2
    • 0027459198 scopus 로고
    • Mdm2 expression is induced by wild type p53 activity
    • Barak, Y., T. Juven, R. Haffner, and M. Oren. 1993. Mdm2 expression is induced by wild type p53 activity. EMBO J. 12: 461-468.
    • (1993) EMBO J. , vol.12 , pp. 461-468
    • Barak, Y.1    Juven, T.2    Haffner, R.3    Oren, M.4
  • 8
    • 0028325483 scopus 로고
    • Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7
    • Demers, G.W., S.A. Foster, C.L. Halbert, and D.A. Galloway. 1994. Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. Proc. Natl. Acad. Sci. 91: 4382-4386.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 4382-4386
    • Demers, G.W.1    Foster, S.A.2    Halbert, C.L.3    Galloway, D.A.4
  • 10
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRb-family members
    • Dyson, N. 1998. The regulation of E2F by pRb-family members. Genes & Dev. 12: 2245-2262.
    • (1998) Genes & Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 13
    • 0022486653 scopus 로고
    • In vitro establishment is not sufficient prerequisite for transformation by activated ras oncogene
    • Franza, B.R., K. Maruyama, J.I. Garrels, and H.E. Ruley. 1986. In vitro establishment is not sufficient prerequisite for transformation by activated ras oncogene. Cell 44: 409-418.
    • (1986) Cell , vol.44 , pp. 409-418
    • Franza, B.R.1    Maruyama, K.2    Garrels, J.I.3    Ruley, H.E.4
  • 15
    • 0032192140 scopus 로고    scopus 로고
    • The complexity of p53 modulation: Emerging patterns from divergent signals
    • this issue
    • Giaccia, A.J. and M.B. Kastan. 1998. The complexity of p53 modulation: Emerging patterns from divergent signals. Genes & Dev. 12: (this issue).
    • (1998) Genes & Dev. , vol.12
    • Giaccia, A.J.1    Kastan, M.B.2
  • 17
    • 0032574788 scopus 로고    scopus 로고
    • An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control
    • Gualberto, A., K. Aldape, K. Kozakiewicz, and T.D. Tlsty. 1998. An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control. Proc. Natl. Acad. Sci. 95: 5166-5171.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 5166-5171
    • Gualberto, A.1    Aldape, K.2    Kozakiewicz, K.3    Tlsty, T.D.4
  • 18
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J.W., G.R. Adami, N. Wei, K. Keyomarsi, and S.J. Elledge. 1993. The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 19
    • 0026303190 scopus 로고
    • p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts
    • Harvey, D.M. and A.J. Levine. 1991. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes &. Dev. 5: 2375-2385.
    • (1991) Genes &. Dev. , vol.5 , pp. 2375-2385
    • Harvey, D.M.1    Levine, A.J.2
  • 21
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt, Y., R. Maya, A. Kazaz, and M. Oren. 1997. Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 22
    • 0028171968 scopus 로고
    • Mediation of c-Myc-induced apoptosis by p53
    • Hermeking, H. and D. Eick. 1994. Mediation of c-Myc-induced apoptosis by p53. Science 265: 2091-2093.
    • (1994) Science , vol.265 , pp. 2091-2093
    • Hermeking, H.1    Eick, D.2
  • 24
    • 0025969355 scopus 로고
    • Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest
    • Hicks, G.C., S.E. Egan, A.H. Greenberg, and M. Mowat. 1991. Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest. Mol. Cell. Biol. 11: 1344-1352.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1344-1352
    • Hicks, G.C.1    Egan, S.E.2    Greenberg, A.H.3    Mowat, M.4
  • 25
    • 0040433650 scopus 로고
    • Rescue of cells from ras oncogene-induced growth arrest by a second complementing oncogene
    • Hirakawa, T. and H.E. Ruley. 1991. Rescue of cells from ras oncogene-induced growth arrest by a second complementing oncogene. Proc. Natl. Acad. Sci. 85: 1519-1523.
    • (1991) Proc. Natl. Acad. Sci. , vol.85 , pp. 1519-1523
    • Hirakawa, T.1    Ruley, H.E.2
  • 27
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • Honda, R., H. Tanaka, and H. Yasuda. 1997. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 420: 25-27.
    • (1997) FEBS Lett. , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 28
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • Howes, K.A., N. Ransom, D.S. Papermaster, J.G.H. Lasudry, D.M. Albert, and J.J. Windle. 1994. Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes & Dev. 8: 1300-1310.
    • (1994) Genes & Dev. , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, N.2    Papermaster, D.S.3    Lasudry, J.G.H.4    Albert, D.M.5    Windle, J.J.6
  • 29
    • 0029973389 scopus 로고    scopus 로고
    • Cell-cycle control and its watchman
    • Jacks, T. and R.A. Weinberg. 1996. Cell-cycle control and its watchman. Nature 381: 643-644.
    • (1996) Nature , vol.381 , pp. 643-644
    • Jacks, T.1    Weinberg, R.A.2
  • 36
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko, L.J. and C. Prives. 1996. p53: Puzzle and paradigm. Genes & Dev. 10: 1054-1072.
    • (1996) Genes & Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 37
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • Kubbutat, M.H., S.N. Jones, and K.H. Vousden. 1997. Regulation of p53 stability by Mdm2. Nature 387: 299-303.
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 38
    • 0026656853 scopus 로고
    • Wild-type p53 is a cell cycle checkpoint determinant following irradiation
    • Kuerbitz, S.J., B.S. Plunkett, W.V. Walsh, and M.B. Kastan. 1992. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. 89: 7491-7495.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 7491-7495
    • Kuerbitz, S.J.1    Plunkett, B.S.2    Walsh, W.V.3    Kastan, M.B.4
  • 39
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • Land, H., L.F. Parada, and R.A. Weinberg. 1983. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304: 596-602.
    • (1983) Nature , vol.304 , pp. 596-602
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 40
    • 0031931414 scopus 로고    scopus 로고
    • Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
    • Lanni, J.S. and T. Jacks. 1998. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol. Cell. Biol. 18: 1055-1064.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1055-1064
    • Lanni, J.S.1    Jacks, T.2
  • 42
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A.J. 1997. p53, the cellular gatekeeper for growth and division. Cell 88: 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 43
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone, L.R., A. White, J. Sprouse, E. Livanos, T. Jacks, and T.D. Tlsty. 1992. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70: 923-935.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 45
    • 0027262606 scopus 로고
    • Stabilization of the p53 tumor suppressor is induced by adenovirus-5 E1A and accompanies apoptosis
    • Lowe, S.W. and H.E. Ruley. 1993. Stabilization of the p53 tumor suppressor is induced by adenovirus-5 E1A and accompanies apoptosis. Genes & Dev. 7: 535-545.
    • (1993) Genes & Dev. , vol.7 , pp. 535-545
    • Lowe, S.W.1    Ruley, H.E.2
  • 46
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S.W., H.E. Ruley, T. Jacks, and D.E. Housman. 1993. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-966.
    • (1993) Cell , vol.74 , pp. 957-966
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 48
    • 0029013310 scopus 로고
    • Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes
    • Metz, T., A.W. Harris, and J.M. Adams. 1995. Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes. Cell 82: 29-36.
    • (1995) Cell , vol.82 , pp. 29-36
    • Metz, T.1    Harris, A.W.2    Adams, J.M.3
  • 49
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S.D., B.O. Williams, T. Jacks, and R.A. DePinho. 1994. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371: 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 50
    • 0028334011 scopus 로고
    • Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
    • Pan, H. and A.E. Griep. 1994. Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development. Genes & Dev. 8: 1285-1299.
    • (1994) Genes & Dev. , vol.8 , pp. 1285-1299
    • Pan, H.1    Griep, A.E.2
  • 53
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin, X.Q., D.M. Livingston, W.G. Kaelin, Jr., and P.D. Adams. 1994. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. 91: 10918-19022.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 10918-19022
    • Qin, X.Q.1    Livingston, D.M.2    Kaelin Jr., W.G.3    Adams, P.D.4
  • 54
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle, D.E., F. Zindy, R.A. Ashmun, and C.J. Sherr. 1995. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 83: 993-1000.
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 56
    • 0026639932 scopus 로고
    • The adenovirus E1A proteins induce apoptosis which is inhibited by E1B 19K and Bcl-2 proteins
    • Rao, L., M. Debbas, P. Sabbatini, D. Hockenberry, S. Korsmeyer, and E. White. 1992. The adenovirus E1A proteins induce apoptosis which is inhibited by E1B 19K and Bcl-2 proteins. Proc. Natl. Acad. Sci. 89: 7742-7746.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 7742-7746
    • Rao, L.1    Debbas, M.2    Sabbatini, P.3    Hockenberry, D.4    Korsmeyer, S.5    White, E.6
  • 57
    • 0032518917 scopus 로고    scopus 로고
    • Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein
    • Roth, J., M. Dobbelstein, D. Freedman, T. Shenk, and A.J. Levine. 1998. Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J. 17: 554-564.
    • (1998) EMBO J. , vol.17 , pp. 554-564
    • Roth, J.1    Dobbelstein, M.2    Freedman, D.3    Shenk, T.4    Levine, A.J.5
  • 59
    • 0020520517 scopus 로고
    • Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture
    • Ruley, H.E. 1983. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature 304: 602-606.
    • (1983) Nature , vol.304 , pp. 602-606
    • Ruley, H.E.1
  • 60
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano, M., G.J. Hannon, and D. Beach. 1993. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366: 704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 63
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • Shan, B. and W.-H. Lee. 1994. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol. 14: 8166-8173.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.-H.2
  • 64
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C.J. 1996. Cancer cell cycles. Science 274: 1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 70
    • 0032127947 scopus 로고    scopus 로고
    • Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function
    • Thomas, A. and E. White. 1998. Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function. Genes & Dev. 12: 1975-1985.
    • (1998) Genes & Dev. , vol.12 , pp. 1975-1985
    • Thomas, A.1    White, E.2
  • 71
    • 0028376386 scopus 로고
    • Analysis of viral-host protein interactions and tumorigenesis in transgenic mice
    • Van Dyke, T. 1994. Analysis of viral-host protein interactions and tumorigenesis in transgenic mice. Semin. Cancer Biol. 5: 47-60.
    • (1994) Semin. Cancer Biol. , vol.5 , pp. 47-60
    • Van Dyke, T.1
  • 72
    • 0028034199 scopus 로고
    • Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21 waf1/cip1
    • Wagner, A.J., J.M. Kokontis, and N. Hay. 1994. Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21 waf1/cip1. Genes & Dev. 8: 2817-2830.
    • (1994) Genes & Dev. , vol.8 , pp. 2817-2830
    • Wagner, A.J.1    Kokontis, J.M.2    Hay, N.3
  • 73
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R.A. 1995. The retinoblastoma protein and cell cycle control. Cell 81: 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 74
    • 0030900653 scopus 로고    scopus 로고
    • The cat and mouse games that genes, viruses, and cells play
    • _. 1997. The cat and mouse games that genes, viruses, and cells play. Cell 88: 573-575.
    • (1997) Cell , vol.88 , pp. 573-575
  • 75
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • White, E. 1996. Life, death, and the pursuit of apoptosis. Genes & Dev. 10: 1-15.
    • (1996) Genes & Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 76
    • 0026049728 scopus 로고
    • The adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins
    • White, E., R. Cipriani, P. Sabbatini, and A. Demon. 1991. The adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins. J. Virol 65: 2968-2978.
    • (1991) J. Virol , vol.65 , pp. 2968-2978
    • White, E.1    Cipriani, R.2    Sabbatini, P.3    Demon, A.4
  • 77
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • Wu, X. and A.J. Levine. 1994. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. 91: 3602-3606.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 78
    • 0027244853 scopus 로고
    • The p53-mdm-2 autoregulatory feedback loop
    • Wu, X., J.H. Bayle, D. Olson, and A.J. Levine. 1993. The p53-mdm-2 autoregulatory feedback loop. Genes & Dev. 7: 1126-1132.
    • (1993) Genes & Dev. , vol.7 , pp. 1126-1132
    • Wu, X.1    Bayle, J.H.2    Olson, D.3    Levine, A.J.4
  • 80
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin, Y., M.A. Tainsky, F.Z. Bischoff, L.C. Strong, and G.M. Wahl 1992. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70: 937-948.
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5
  • 81
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppressor pathways
    • Zhang, Y., Y. Xiong, and W.G. Yarbrough. 1998. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppressor pathways. Cell 92: 725-734.
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 82
    • 0032145569 scopus 로고    scopus 로고
    • Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
    • Zindy, F., C.M. Eischen, D. Randle, T. Kamijo, J.L. Cleveland, C.I. Sherr, and M.F. Roussel. 1998. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes & Dev. 12: 2424-2434.
    • (1998) Genes & Dev. , vol.12 , pp. 2424-2434
    • Zindy, F.1    Eischen, C.M.2    Randle, D.3    Kamijo, T.4    Cleveland, J.L.5    Sherr, C.I.6    Roussel, M.F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.