메뉴 건너뛰기




Volumn 5, Issue 3, 1999, Pages 171-178

DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde?

Author keywords

Antitumor agents; Multifunctional proteins; Oncogenesis; Topoisomerase I

Indexed keywords

CAMPTOTHECIN; DNA; DNA TOPOISOMERASE; PROTEIN P53;

EID: 0032759443     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1053/paor.1999.0209     Document Type: Article
Times cited : (44)

References (85)
  • 1
    • 15844415445 scopus 로고    scopus 로고
    • Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I
    • Rossi F, Labourier E, Forne T. Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I. Nature. 381:1996;80-82.
    • (1996) Nature , vol.381 , pp. 80-82
    • Rossi, F.1    Labourier, E.2    Forne, T.3
  • 2
    • 0015222656 scopus 로고
    • Interaction between DNA and an Escherichia coli protein omega
    • Wang J C. Interaction between DNA and an Escherichia coli protein omega. J Mol Biol. 14:1971;523-533.
    • (1971) J Mol Biol , vol.14 , pp. 523-533
    • Wang, J.C.1
  • 3
    • 0015262632 scopus 로고
    • An activity from mammalian cells that untwists superhelical DNA; A possible swivel for DNA replication
    • Champoux J J, Dulbecco R. An activity from mammalian cells that untwists superhelical DNA; a possible swivel for DNA replication. Proc Natl Acad Sci USA. 69:1972;143-146.
    • (1972) Proc Natl Acad Sci USA , vol.69 , pp. 143-146
    • Champoux, J.J.1    Dulbecco, R.2
  • 4
    • 0016786854 scopus 로고
    • Partial purification of Omega protein from calf thymus
    • Pulleyblank D E, Morgan A R. Partial purification of Omega protein from calf thymus. Biochemistry. 14:1975;5205-5209.
    • (1975) Biochemistry , vol.14 , pp. 5205-5209
    • Pulleyblank, D.E.1    Morgan, A.R.2
  • 5
    • 0017885393 scopus 로고
    • The DNA untwisting enzyme from Saccharomyces cerevisiae. Partial purification and characterization
    • Durnford J M, Champoux J J. The DNA untwisting enzyme from Saccharomyces cerevisiae. Partial purification and characterization. J Biol Chem. 253:1978;1086-1089.
    • (1978) J Biol Chem , vol.253 , pp. 1086-1089
    • Durnford, J.M.1    Champoux, J.J.2
  • 6
    • 0020480673 scopus 로고
    • Drosophila topoisomerase I: Isolation, purification and characterization
    • Javaherian K, Tse Y C, Vega J. Drosophila topoisomerase I: isolation, purification and characterization. Nucleic Acids Res. 10:1982;6945-6955.
    • (1982) Nucleic Acids Res , vol.10 , pp. 6945-6955
    • Javaherian, K.1    Tse, Y.C.2    Vega, J.3
  • 7
    • 0020950974 scopus 로고
    • HeLa toposiomerase I
    • Liu L F. HeLa toposiomerase I. Methods Enzymol. 100:1983;133-137.
    • (1983) Methods Enzymol , vol.100 , pp. 133-137
    • Liu, L.F.1
  • 8
    • 0021104780 scopus 로고
    • A type I DNA topoisomerase from Trypanosoma cruzi
    • Riou G F, Gabillot M, Douc-Rasy S. A type I DNA topoisomerase from Trypanosoma cruzi. Eur J Biochem. 134:1983;479-484.
    • (1983) Eur J Biochem , vol.134 , pp. 479-484
    • Riou, G.F.1    Gabillot, M.2    Douc-Rasy, S.3
  • 9
    • 0023442459 scopus 로고
    • Identification of a vaccinia virus gene encoding a type I DNA topoisomerase
    • Shuman S, Moss B. Identification of a vaccinia virus gene encoding a type I DNA topoisomerase. Proc Natl Acad Sci USA. 84:1987;7478-7482.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7478-7482
    • Shuman, S.1    Moss, B.2
  • 10
    • 0024324482 scopus 로고
    • A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase
    • Wallis J W, Chrebet G, Brodsky G. A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase. Cell. 58:1989;409-419.
    • (1989) Cell , vol.58 , pp. 409-419
    • Wallis, J.W.1    Chrebet, G.2    Brodsky, G.3
  • 11
    • 0029986401 scopus 로고    scopus 로고
    • Human TOP3: A single-copy gene encoding DNA topoisomerase III
    • Hanai R, Caron P R, Wang J C. Human TOP3: a single-copy gene encoding DNA topoisomerase III. Proc Natl Acad Sci USA. 93:1996;3653-3657.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3653-3657
    • Hanai, R.1    Caron, P.R.2    Wang, J.C.3
  • 12
    • 0029986467 scopus 로고    scopus 로고
    • Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
    • Stewart L, Ireton G C, Parker L H. Biochemical and biophysical analyses of recombinant forms of human topoisomerase I. J Biol Chem. 271:1996;7593-7601.
    • (1996) J Biol Chem , vol.271 , pp. 7593-7601
    • Stewart, L.1    Ireton, G.C.2    Parker, L.H.3
  • 13
    • 0032489634 scopus 로고    scopus 로고
    • Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
    • Redinbo M R, Stewart L, Kuhn P. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 279:1998;504-513.
    • (1998) Science , vol.279 , pp. 504-513
    • Redinbo, M.R.1    Stewart, L.2    Kuhn, P.3
  • 14
    • 0344307766 scopus 로고
    • Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function
    • Alsner J, Svejstrup J Q, Kjeldsen E. Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function. J Biol Chem. 26:1992;2408-2411.
    • (1992) J Biol Chem , vol.26 , pp. 2408-2411
    • Alsner, J.1    Svejstrup, J.Q.2    Kjeldsen, E.3
  • 15
    • 0032526604 scopus 로고    scopus 로고
    • Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor
    • Labourier E, Rossi F, Gallouzi I E. Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor. Nucleic Acids Res. 26:1998;2955-2962.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2955-2962
    • Labourier, E.1    Rossi, F.2    Gallouzi, I.E.3
  • 16
    • 0032526626 scopus 로고    scopus 로고
    • The C-terminal domain but not the tyrosine 723 of human DNA topoisomerase I active site contributes to kinase activity
    • Rossi F, Labourier E, Gallouzi I E. The C-terminal domain but not the tyrosine 723 of human DNA topoisomerase I active site contributes to kinase activity. Nucleic Acids Res. 26:1998;2963-2970.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2963-2970
    • Rossi, F.1    Labourier, E.2    Gallouzi, I.E.3
  • 17
    • 0000482574 scopus 로고
    • Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2
    • Juan C C, Hwang J, Liu A A. Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2. Proc Natl Acad Sci USA. 85:1988;8910-8913.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8910-8913
    • Juan, C.C.1    Hwang, J.2    Liu, A.A.3
  • 18
    • 0025788501 scopus 로고
    • Structure of the human type I DNA topoisomerase gene
    • Kunze N, Yang G, Dolberg M. Structure of the human type I DNA topoisomerase gene. J Biol Chem. 266:1991;9610-9616.
    • (1991) J Biol Chem , vol.266 , pp. 9610-9616
    • Kunze, N.1    Yang, G.2    Dolberg, M.3
  • 19
    • 0025612753 scopus 로고
    • Structural characterization of the human DNA topoisomerase I gene promoter
    • Kunze N, Klein M, Richter A. Structural characterization of the human DNA topoisomerase I gene promoter. Eur J Biochem. 194:1990;323-330.
    • (1990) Eur J Biochem , vol.194 , pp. 323-330
    • Kunze, N.1    Klein, M.2    Richter, A.3
  • 20
    • 0027369893 scopus 로고
    • The promoter region of the human type-I DNA-topoisomerase gene. Protein-binding sites and sequences involved in transcriptional regulation
    • Heiland S, Knippers R, Kunze N. The promoter region of the human type-I DNA-topoisomerase gene. Protein-binding sites and sequences involved in transcriptional regulation. Eur J Biochem. 21:1993;813-822.
    • (1993) Eur J Biochem , vol.21 , pp. 813-822
    • Heiland, S.1    Knippers, R.2    Kunze, N.3
  • 21
    • 0027235828 scopus 로고
    • Increased synthesis and degradation of DNA topoisomerase I during the initial phase of human T lymphocyte proliferation
    • Hwong C L, Chen C Y, Shang H F. Increased synthesis and degradation of DNA topoisomerase I during the initial phase of human T lymphocyte proliferation. J Biol Chem. 268:1993;18982-18986.
    • (1993) J Biol Chem , vol.268 , pp. 18982-18986
    • Hwong, C.L.1    Chen, C.Y.2    Shang, H.F.3
  • 22
    • 0028923568 scopus 로고
    • Changes in topoisomerase I levels and localization during myeloid maturation in vitro and in vivo
    • Kaufmann S H, Charron M, Burke P J. Changes in topoisomerase I levels and localization during myeloid maturation in vitro and in vivo. Cancer Res. 55:1995;1255-1260.
    • (1995) Cancer Res , vol.55 , pp. 1255-1260
    • Kaufmann, S.H.1    Charron, M.2    Burke, P.J.3
  • 23
    • 0025317457 scopus 로고
    • Expression of the topoisomerase I gene in serum stimulated human fibroblasts
    • Romig H, Richter A. Expression of the topoisomerase I gene in serum stimulated human fibroblasts. Biochim Biophys Acta. 1048:1990;274-280.
    • (1990) Biochim Biophys Acta , vol.1048 , pp. 274-280
    • Romig, H.1    Richter, A.2
  • 24
    • 0030854371 scopus 로고    scopus 로고
    • Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin
    • Desai S D, Liu L F, Vazquez-Abad D. Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin. J Biol Chem. 272:1997;24159-24164.
    • (1997) J Biol Chem , vol.272 , pp. 24159-24164
    • Desai, S.D.1    Liu, L.F.2    Vazquez-Abad, D.3
  • 25
    • 0000266944 scopus 로고
    • Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle
    • Heck M M, Hittelman W N. Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle. Proc Natl Acad Sci USA. 85:1988;1086-1090.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1086-1090
    • Heck, M.M.1    Hittelman, W.N.2
  • 26
    • 0028795337 scopus 로고
    • Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy
    • Baker S D, Wadkins R M, Stewart C F. Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy. Cytometry. 19:1995;134-145.
    • (1995) Cytometry , vol.19 , pp. 134-145
    • Baker, S.D.1    Wadkins, R.M.2    Stewart, C.F.3
  • 27
    • 0029922970 scopus 로고    scopus 로고
    • Elevations of DNA topoisomerase I catalytic activity and immunoprotein in human malignancies
    • Bronstein I B, Vorobyev S, Timofeev A. Elevations of DNA topoisomerase I catalytic activity and immunoprotein in human malignancies. Oncol Res. 8:1996;17-25.
    • (1996) Oncol Res , vol.8 , pp. 17-25
    • Bronstein, I.B.1    Vorobyev, S.2    Timofeev, A.3
  • 28
    • 0022067647 scopus 로고
    • Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA
    • Muller M T, Pfund W P, Mehta V B. Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA. EMBO J. 4:1985;1237-1243.
    • (1985) EMBO J , vol.4 , pp. 1237-1243
    • Muller, M.T.1    Pfund, W.P.2    Mehta, V.B.3
  • 29
    • 0024520253 scopus 로고
    • Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus
    • Hirano T, Konoha G, Toda T. Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus. J Cell Biol. 108:1989;243-253.
    • (1989) J Cell Biol , vol.108 , pp. 243-253
    • Hirano, T.1    Konoha, G.2    Toda, T.3
  • 30
    • 0031018820 scopus 로고    scopus 로고
    • Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities
    • Meyer K N, Kjeldsen E, Straub T. Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities. J Cell Biol. 136:1997;775-788.
    • (1997) J Cell Biol , vol.136 , pp. 775-788
    • Meyer, K.N.1    Kjeldsen, E.2    Straub, T.3
  • 31
    • 0009543358 scopus 로고
    • Isolation of type I and II DNA topoisomerase mutants from fission yeast: Single and double mutants show different phenotypes in cell growth and chromatin organization
    • Uemura T, Yanagida M. Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization. EMBO J. 3:1984;1737-1744.
    • (1984) EMBO J , vol.3 , pp. 1737-1744
    • Uemura, T.1    Yanagida, M.2
  • 32
    • 0021931572 scopus 로고
    • Cloning, characterization and sequence of the yeast topoisomerase I gene
    • Thrash C, Bankier A T, Barell B G. Cloning, characterization and sequence of the yeast topoisomerase I gene. Proc Natl Acad Sci USA. 82:1985;4374-4378.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4374-4378
    • Thrash, C.1    Bankier, A.T.2    Barell, B.G.3
  • 33
    • 0024338961 scopus 로고
    • Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae
    • Kim R A, Wang J C. Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae. J Mol Biol. 208:1989;257-267.
    • (1989) J Mol Biol , vol.208 , pp. 257-267
    • Kim, R.A.1    Wang, J.C.2
  • 34
    • 0027440903 scopus 로고
    • DNA topoisomerase I controls the kinetics of promoter activation and DNA topology in Saccharomyces cerevisiae
    • Di Mauro E G, Camilloni E G, Verdone L. DNA topoisomerase I controls the kinetics of promoter activation and DNA topology in Saccharomyces cerevisiae. Mol Cell Biol. 13:1993;6702-6710.
    • (1993) Mol Cell Biol , vol.13 , pp. 6702-6710
    • Di Mauro, E.G.1    Camilloni, E.G.2    Verdone, L.3
  • 35
    • 0027165312 scopus 로고
    • DNA topoisomerase I is essential in Drosophila melanogaster
    • Lee M P, Brown S D, Chen A. DNA topoisomerase I is essential in Drosophila melanogaster. Proc Natl Acad Sci USA. 90:1993;6656-6660.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6656-6660
    • Lee, M.P.1    Brown, S.D.2    Chen, A.3
  • 36
    • 0029912651 scopus 로고    scopus 로고
    • Targeted disruption of the mouse topoisomerase I gene by camptothecin selection
    • Morham S G, Kluckman K D, Voulomanos N. Targeted disruption of the mouse topoisomerase I gene by camptothecin selection. Mol Cell Biol. 16:1996;6804-6809.
    • (1996) Mol Cell Biol , vol.16 , pp. 6804-6809
    • Morham, S.G.1    Kluckman, K.D.2    Voulomanos, N.3
  • 37
    • 2642625363 scopus 로고
    • Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro
    • Yang L, Wold M S, Li J J. Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. Proc Natl Acad Sci USA. 84:1987;950-954.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 950-954
    • Yang, L.1    Wold, M.S.2    Li, J.J.3
  • 38
    • 0022508558 scopus 로고
    • Topoisomerase I interacts with transcribed regions in Drosophila cells
    • Gilmour D S, Pflugfelder G, Wang J C. Topoisomerase I interacts with transcribed regions in Drosophila cells. Cell. 44:1986;401-407.
    • (1986) Cell , vol.44 , pp. 401-407
    • Gilmour, D.S.1    Pflugfelder, G.2    Wang, J.C.3
  • 39
    • 0023277908 scopus 로고
    • Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene
    • Garg L C, Di Angelo S, Jacob S T. Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene. Proc Natl Acad Sci USA. 84:1987;3185-3188.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 3185-3188
    • Garg, L.C.1    Di Angelo, S.2    Jacob, S.T.3
  • 40
    • 0027186443 scopus 로고
    • DNA topoisomerase I is involved in both repression and activation of transcription
    • Merino A, Madden K R, Lane W S. DNA topoisomerase I is involved in both repression and activation of transcription. Nature. 365:1993;227-232.
    • (1993) Nature , vol.365 , pp. 227-232
    • Merino, A.1    Madden, K.R.2    Lane, W.S.3
  • 41
    • 0031049483 scopus 로고    scopus 로고
    • Topoisomerase I enhances TFIID-TFIIA complex assembly during activaton of transcription
    • Shykind B M, Kim J, Stewart L. Topoisomerase I enhances TFIID-TFIIA complex assembly during activaton of transcription. Genes Dev. 11:1997;397-407.
    • (1997) Genes Dev , vol.11 , pp. 397-407
    • Shykind, B.M.1    Kim, J.2    Stewart, L.3
  • 42
    • 0027138674 scopus 로고
    • Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II
    • Kretzschmar M, Meisternst M, Roeder R G. Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. Proc Natl Acad Sci USA. 90:1993;11508-11512.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11508-11512
    • Kretzschmar, M.1    Meisternst, M.2    Roeder, R.G.3
  • 43
    • 0022409106 scopus 로고
    • Association of crossover points with topoisomerase I cleavage sites: A model for nonhomologous recombination
    • Bullock P, Champoux J J, Botchan M. Association of crossover points with topoisomerase I cleavage sites: a model for nonhomologous recombination. Science. 230:1985;954-958.
    • (1985) Science , vol.230 , pp. 954-958
    • Bullock, P.1    Champoux, J.J.2    Botchan, M.3
  • 44
    • 0032549763 scopus 로고    scopus 로고
    • Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases
    • Cheng C, Kussie P, Pavletich N. Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases. Cell. 92:1998;841-850.
    • (1998) Cell , vol.92 , pp. 841-850
    • Cheng, C.1    Kussie, P.2    Pavletich, N.3
  • 45
    • 0029960067 scopus 로고    scopus 로고
    • Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae
    • Zhu J, Schiestl R H. Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae. Mol Cell Biol. 16:1996;1805-1812.
    • (1996) Mol Cell Biol , vol.16 , pp. 1805-1812
    • Zhu, J.1    Schiestl, R.H.2
  • 46
    • 0021632246 scopus 로고
    • DNA sequence studies of simian virus 40 chromosomal excision and integration in rat cells
    • Bullock P, Forrester W, Botchan M. DNA sequence studies of simian virus 40 chromosomal excision and integration in rat cells. J Mol Biol. 174:1984;55-84.
    • (1984) J Mol Biol , vol.174 , pp. 55-84
    • Bullock, P.1    Forrester, W.2    Botchan, M.3
  • 47
    • 0024334177 scopus 로고
    • Features of two hepatitis B virus (HBV) DNA integrations suggest mechanisms of HBV integration
    • Hino O, Ohtake K, Rogler C E. Features of two hepatitis B virus (HBV) DNA integrations suggest mechanisms of HBV integration. J Virol. 63:1989;2638-2643.
    • (1989) J Virol , vol.63 , pp. 2638-2643
    • Hino, O.1    Ohtake, K.2    Rogler, C.E.3
  • 48
    • 0025873579 scopus 로고
    • Topoisomerase I-mediated integration of hepadnavirus DNA in vitro
    • Wang H P, Rogler C E. Topoisomerase I-mediated integration of hepadnavirus DNA in vitro. J Virol. 65:1991;2381-2392.
    • (1991) J Virol , vol.65 , pp. 2381-2392
    • Wang, H.P.1    Rogler, C.E.2
  • 49
    • 0028122271 scopus 로고
    • International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents
    • Anderson R D, Berger N A. International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents. Mutat Res. 309:1994;109-142.
    • (1994) Mutat Res , vol.309 , pp. 109-142
    • Anderson, R.D.1    Berger, N.A.2
  • 50
    • 0029863952 scopus 로고    scopus 로고
    • Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage
    • Lanza A, Tornaletti S, Rodolfo C. Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage. J Biol Chem. 271:1996;6978-6986.
    • (1996) J Biol Chem , vol.271 , pp. 6978-6986
    • Lanza, A.1    Tornaletti, S.2    Rodolfo, C.3
  • 51
    • 0030698003 scopus 로고    scopus 로고
    • Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects
    • Pourquier P, Pilon A A, Kohlhagen G. Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects. J Biol Chem. 272:1997;26441-26447.
    • (1997) J Biol Chem , vol.272 , pp. 26441-26447
    • Pourquier, P.1    Pilon, A.A.2    Kohlhagen, G.3
  • 52
    • 0030661769 scopus 로고    scopus 로고
    • The involvement of topoisomerase I in the induction of DNA-protein crosslinks and DNA single-strand breaks in cells of ultraviolet-irradiated human and frog cell lines
    • Rosenstein B S, Subramanian D, Muller M T. The involvement of topoisomerase I in the induction of DNA-protein crosslinks and DNA single-strand breaks in cells of ultraviolet-irradiated human and frog cell lines. Radiat Res. 148:1997;575-579.
    • (1997) Radiat Res , vol.148 , pp. 575-579
    • Rosenstein, B.S.1    Subramanian, D.2    Muller, M.T.3
  • 53
    • 0032030882 scopus 로고    scopus 로고
    • Ultraviolet-induced DNA damage stimulates topoisomerase I-DNA complex formation in vivo: Possible relationship with DNA repair
    • Subramanian D, Rosenstein B S, Muller M T. Ultraviolet-induced DNA damage stimulates topoisomerase I-DNA complex formation in vivo: possible relationship with DNA repair. Cancer Res. 58:1998;976-984.
    • (1998) Cancer Res , vol.58 , pp. 976-984
    • Subramanian, D.1    Rosenstein, B.S.2    Muller, M.T.3
  • 54
    • 0031463309 scopus 로고    scopus 로고
    • Cisplatin and UV-damaged DNA lure the basal transcription factor TFIID/TBP
    • Vichi P, Coin F, Renaud J P. Cisplatin and UV-damaged DNA lure the basal transcription factor TFIID/TBP. EMBO J. 16:1997;7444-7456.
    • (1997) EMBO J , vol.16 , pp. 7444-7456
    • Vichi, P.1    Coin, F.2    Renaud, J.P.3
  • 55
    • 0029999538 scopus 로고    scopus 로고
    • Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae
    • Castano I B, Brzoska P M, Sadoff B U. Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. Genes Dev. 10:1996;2564-2576.
    • (1996) Genes Dev , vol.10 , pp. 2564-2576
    • Castano, I.B.1    Brzoska, P.M.2    Sadoff, B.U.3
  • 56
    • 0030874421 scopus 로고    scopus 로고
    • ATP-dependent positive supercoiling of DNA by 13S condensin: A biochemical implication for chromosome condensation
    • Kimura K, Hirano T. ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation. Cell. 90:1997;625-634.
    • (1997) Cell , vol.90 , pp. 625-634
    • Kimura, K.1    Hirano, T.2
  • 57
    • 0022153791 scopus 로고
    • Topoisomerase I phosphorylation in vitro and in rapidly growing Novikoff hepatoma cells
    • Durban E, Goodenough M, Mills J. Topoisomerase I phosphorylation in vitro and in rapidly growing Novikoff hepatoma cells. EMBO J. 4:1985;2921-2926.
    • (1985) EMBO J , vol.4 , pp. 2921-2926
    • Durban, E.1    Goodenough, M.2    Mills, J.3
  • 58
    • 0024276809 scopus 로고
    • Regulation of Xenopus laevis DNA topoisomerase I activity by phosphorylation in vitro
    • Kaiserman H B, Ingebritsen T S, Benbow R M. Regulation of Xenopus laevis DNA topoisomerase I activity by phosphorylation in vitro. Biochemistry. 27:1988;3216-3222.
    • (1988) Biochemistry , vol.27 , pp. 3216-3222
    • Kaiserman, H.B.1    Ingebritsen, T.S.2    Benbow, R.M.3
  • 59
    • 0024804104 scopus 로고
    • Protein kinase C phosphorylates DNA topoisomerase I
    • Samuels D S, Shimizu Y, Shimizu N. Protein kinase C phosphorylates DNA topoisomerase I. FEBS Lett. 259:1989;57-60.
    • (1989) FEBS Lett , vol.259 , pp. 57-60
    • Samuels, D.S.1    Shimizu, Y.2    Shimizu, N.3
  • 60
    • 0025297468 scopus 로고
    • Phosphorylation of mammalian DNA topoisomerase I and activation by protein kinase C
    • Pommier Y, Kerrigan D, Hartman K D. Phosphorylation of mammalian DNA topoisomerase I and activation by protein kinase C. J Biol Chem. 265:1990;9418-9422.
    • (1990) J Biol Chem , vol.265 , pp. 9418-9422
    • Pommier, Y.1    Kerrigan, D.2    Hartman, K.D.3
  • 61
    • 0026471627 scopus 로고
    • Comparison of biochemical properties of DNA-topoisomerase I from normal and regenerating liver
    • Tournier M F, Sobczak J, de Nechaud B. Comparison of biochemical properties of DNA-topoisomerase I from normal and regenerating liver. Eur J Biochem. 210:1992;359-364.
    • (1992) Eur J Biochem , vol.210 , pp. 359-364
    • Tournier, M.F.1    Sobczak, J.2    De Nechaud, B.3
  • 62
    • 0028940326 scopus 로고
    • Cell cycle-specific and transcription-related phosphorylation of mammalian topoisomerase I
    • D'Arpa P, Liu L F. Cell cycle-specific and transcription-related phosphorylation of mammalian topoisomerase I. Exp Cell Res. 217:1995;125-131.
    • (1995) Exp Cell Res , vol.217 , pp. 125-131
    • D'Arpa, P.1    Liu, L.F.2
  • 63
    • 0024571820 scopus 로고
    • ADP-ribosylation of ADPR-transferase and topoisomerase I in intact mouse epidermal cells JB6
    • Krupitza G, Cerutti P. ADP-ribosylation of ADPR-transferase and topoisomerase I in intact mouse epidermal cells JB6. Biochemistry. 28:1989;2034-2040.
    • (1989) Biochemistry , vol.28 , pp. 2034-2040
    • Krupitza, G.1    Cerutti, P.2
  • 64
    • 0028094758 scopus 로고
    • Down-regulation of topoisomerase I in mammalian cells following ionizing radiation
    • Boothman D A, Fukunaga N, Wang M. Down-regulation of topoisomerase I in mammalian cells following ionizing radiation. Cancer Res. 54:1994;4618-4626.
    • (1994) Cancer Res , vol.54 , pp. 4618-4626
    • Boothman, D.A.1    Fukunaga, N.2    Wang, M.3
  • 65
    • 0021111988 scopus 로고
    • Poly(ADP-ribosylation) of a DNA topoisomerase
    • Ferro A M, Higgins N P, Olivera B M. Poly(ADP-ribosylation) of a DNA topoisomerase. J Biol Chem. 258:1983;6000-6003.
    • (1983) J Biol Chem , vol.258 , pp. 6000-6003
    • Ferro, A.M.1    Higgins, N.P.2    Olivera, B.M.3
  • 66
    • 0021093617 scopus 로고
    • DNA topoisomerase I from calf thymus is inhibited in vitro by poly(ADP-ribosylation)
    • Jongstra-Bilen J, Ittel M E, Niedergang C. DNA topoisomerase I from calf thymus is inhibited in vitro by poly(ADP-ribosylation). Eur J Biochem. 136:1983;391-396.
    • (1983) Eur J Biochem , vol.136 , pp. 391-396
    • Jongstra-Bilen, J.1    Ittel, M.E.2    Niedergang, C.3
  • 67
    • 0024427202 scopus 로고
    • Poly(ADP-ribose)-mediated post-translational modification of chromatin-associated human topoisomerase I. Inhibitory effects on catalytic activity
    • Kasid U N, Halligan B, Liu L F. Poly(ADP-ribose)-mediated post-translational modification of chromatin-associated human topoisomerase I. Inhibitory effects on catalytic activity. J Biol Chem. 264:1989;18687-18692.
    • (1989) J Biol Chem , vol.264 , pp. 18687-18692
    • Kasid, U.N.1    Halligan, B.2    Liu, L.F.3
  • 68
    • 0023514097 scopus 로고
    • Poly(ADP-ribose) synthase is the major endogenous nonhistone acceptor for poly(ADP-ribose) in alkylated rat hepatoma cells
    • Adamietz P. Poly(ADP-ribose) synthase is the major endogenous nonhistone acceptor for poly(ADP-ribose) in alkylated rat hepatoma cells. Eur J Biochem. 169:1987;365-372.
    • (1987) Eur J Biochem , vol.169 , pp. 365-372
    • Adamietz, P.1
  • 69
    • 0021319547 scopus 로고
    • Poly(ADP-ribosylation) of DNA topoisomerase I from calf thymus
    • Ferro A M, Olivera B M. Poly(ADP-ribosylation) of DNA topoisomerase I from calf thymus. J Biol Chem. 259:1984;547-554.
    • (1984) J Biol Chem , vol.259 , pp. 547-554
    • Ferro, A.M.1    Olivera, B.M.2
  • 70
    • 0021111554 scopus 로고
    • Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins
    • Javaherian K, Liu L F. Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins. Nucleic Acids Res. 11:1983;461-472.
    • (1983) Nucleic Acids Res , vol.11 , pp. 461-472
    • Javaherian, K.1    Liu, L.F.2
  • 71
    • 0023805882 scopus 로고
    • Association of DNA topoisomerase I and RNA polymerase I: A possible role for topoisomerase I in ribosomal gene transcription
    • Rose K M, Szopa J, Han F S. Association of DNA topoisomerase I and RNA polymerase I: a possible role for topoisomerase I in ribosomal gene transcription. Chromosoma. 96:1988;411-416.
    • (1988) Chromosoma , vol.96 , pp. 411-416
    • Rose, K.M.1    Szopa, J.2    Han, F.S.3
  • 72
    • 0030047434 scopus 로고    scopus 로고
    • Identification of a nucleolin binding site in human topoisomerase I
    • Bharti A K, Olson M O, Kufe D W. Identification of a nucleolin binding site in human topoisomerase I. J Biol Chem. 271:1996;1993-1997.
    • (1996) J Biol Chem , vol.271 , pp. 1993-1997
    • Bharti, A.K.1    Olson, M.O.2    Kufe, D.W.3
  • 73
    • 0028072001 scopus 로고
    • Casein kinase II stimulates Xenopus laevis DNA topoisomerase I by physical association
    • Kordiyak G J, Jakes S, Ingebritsen T S. Casein kinase II stimulates Xenopus laevis DNA topoisomerase I by physical association. Biochemistry. 33:1994;13484-13491.
    • (1994) Biochemistry , vol.33 , pp. 13484-13491
    • Kordiyak, G.J.1    Jakes, S.2    Ingebritsen, T.S.3
  • 74
    • 0029971854 scopus 로고    scopus 로고
    • Modulation of DNA topoisomerase I activity by p53
    • Gobert C, Bracco L, Rossi F. Modulation of DNA topoisomerase I activity by p53. Biochemistry. 35:1996;5778-5786.
    • (1996) Biochemistry , vol.35 , pp. 5778-5786
    • Gobert, C.1    Bracco, L.2    Rossi, F.3
  • 75
    • 0032523932 scopus 로고    scopus 로고
    • Wild-type and mutant forms of p53 activate human topoisomerase I: A possible mechanism for gain of function in mutants
    • Albor A, Kaku S, Kulesz-Martin M. Wild-type and mutant forms of p53 activate human topoisomerase I: a possible mechanism for gain of function in mutants. Cancer Res. 58:1998;2091-2094.
    • (1998) Cancer Res , vol.58 , pp. 2091-2094
    • Albor, A.1    Kaku, S.2    Kulesz-Martin, M.3
  • 76
    • 0032253818 scopus 로고    scopus 로고
    • DNA topoisomerases as repair enzymes: Mechanism(s) of action and regulation by p53
    • Larsen A K, Gobert C, Gilbert C. DNA topoisomerases as repair enzymes: Mechanism(s) of action and regulation by p53. Acta Biochim Pol. 45:1998;535-544.
    • (1998) Acta Biochim Pol , vol.45 , pp. 535-544
    • Larsen, A.K.1    Gobert, C.2    Gilbert, C.3
  • 77
    • 0033621189 scopus 로고    scopus 로고
    • The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53
    • Gobert C, Skaldanowski A, Larsen A K. The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53. Proc Natl Acad Sci USA, in press. 1999.
    • (1999) Proc Natl Acad Sci USA, in Press
    • Gobert, C.1    Skaldanowski, A.2    Larsen, A.K.3
  • 78
    • 0028075751 scopus 로고
    • Topoisomerase I and II activity in human breast, cervix, lung and colon cancer
    • Mc Leod H L, Douglas F, Oates M. Topoisomerase I and II activity in human breast, cervix, lung and colon cancer. Int J Cancer. 59:1994;607-611.
    • (1994) Int J Cancer , vol.59 , pp. 607-611
    • Mc Leod, H.L.1    Douglas, F.2    Oates, M.3
  • 79
    • 0031408435 scopus 로고    scopus 로고
    • DNA topoisomerase I, a new target for the treatment of neuroblastoma
    • Vassal G, Pondarré C, Cappelli C. DNA topoisomerase I, a new target for the treatment of neuroblastoma. Eur J Cancer. 33:1997;2011-2015.
    • (1997) Eur J Cancer , vol.33 , pp. 2011-2015
    • Vassal, G.1    Pondarré, C.2    Cappelli, C.3
  • 80
    • 0028006314 scopus 로고
    • Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: Demonstration of tumor-type specificity and implications for cancer chemotherapy
    • Husain I, Mohler J L, Seigler H. Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: demonstration of tumor-type specificity and implications for cancer chemotherapy. Cancer Res. 54:1994;539-546.
    • (1994) Cancer Res , vol.54 , pp. 539-546
    • Husain, I.1    Mohler, J.L.2    Seigler, H.3
  • 81
    • 0024358188 scopus 로고
    • DNA topoisomerase I targeted chemotherapy of human colon cancer in xenografs
    • Giovanella B C, Steblin J S, Wall M E. DNA topoisomerase I targeted chemotherapy of human colon cancer in xenografs. Science. 246:1989;1046-1048.
    • (1989) Science , vol.246 , pp. 1046-1048
    • Giovanella, B.C.1    Steblin, J.S.2    Wall, M.E.3
  • 82
    • 0031787528 scopus 로고    scopus 로고
    • Expression of DNA topoisomerase I, DNA topoisomerase II-alpha, and p53 in metastatic malignant melanoma
    • Lynch B J, Komaromy-Hiller G, Bronstein I B. Expression of DNA topoisomerase I, DNA topoisomerase II-alpha, and p53 in metastatic malignant melanoma. Hum Pathol. 29:1998;1240-1245.
    • (1998) Hum Pathol , vol.29 , pp. 1240-1245
    • Lynch, B.J.1    Komaromy-Hiller, G.2    Bronstein, I.B.3
  • 83
    • 0029758307 scopus 로고    scopus 로고
    • Variation in topoisomerase I gene copy number as a mechanism for intrinsic drug sensitivity
    • McLeod H L, Keith W N. Variation in topoisomerase I gene copy number as a mechanism for intrinsic drug sensitivity. Br J Cancer. 74:1996;508-512.
    • (1996) Br J Cancer , vol.74 , pp. 508-512
    • McLeod, H.L.1    Keith, W.N.2
  • 84
    • 0006465595 scopus 로고    scopus 로고
    • The roles of ubiquitin-dependent proteolysis in determining the sensitivity/resistance of tumor cells to topoisomerase inhibitors
    • Liu L F, Desai S D, Wu J X. The roles of ubiquitin-dependent proteolysis in determining the sensitivity/resistance of tumor cells to topoisomerase inhibitors. Proc Am Ass Cancer Res. 40:1999;775-775.
    • (1999) Proc Am Ass Cancer Res , vol.40 , pp. 775-775
    • Liu, L.F.1    Desai, S.D.2    Wu, J.X.3
  • 85
    • 0032189251 scopus 로고    scopus 로고
    • Cellular resistance to topoisomerase-targeted drugs: From drug uptake to cell death
    • Larsen A K, Skladanowski A. Cellular resistance to topoisomerase-targeted drugs: from drug uptake to cell death. Biochem Biophys Acta. 1400:1998;257-274.
    • (1998) Biochem Biophys Acta , vol.1400 , pp. 257-274
    • Larsen, A.K.1    Skladanowski, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.