Activated Raf-1 causes growth arrest in human small cell lung cancer cells

Journal of Clinical Investigation

Volumn 101, Issue 1, 1998, Pages 153-159

  Ravi, Rajani K ^a   Weber, Erich ^a,f   McMahon, Martin ^b   Williams, Jerry R ^a   Baylin, Stephen ^a   Mal, Asoke ^c   Harter, Marian L ^c   Dillehay, Larry E ^a   Claudio, Pier Paolo ^d   Giordano, Antonio ^d   Nelkin, Barry D ^a   Mabry, Mack ^e  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

^e Matrix Pharmaceutical Inc   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Activated raf; Cell cycle; MAP kinase; MEK inhibitor PD098059; p27(kip1); SCLC

Indexed keywords

CYCLIN DEPENDENT KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE; CONTROLLED STUDY; ENZYME ACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; PRIORITY JOURNAL;

EID: 0031985094     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI831     Document Type: Article

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