Proteasome-Mediated Degradation of the C-terminus of the Alzheimer's Disease β-Amyloid Protein Precursor: Effect of C-Terminal Truncation on Production of β-Amyloid Protein

Journal of Neuroscience Research

Volumn 74, Issue 3, 2003, Pages 378-385

  Nunan, Janelle ^a,b   Williamson, Nicholas A ^a   Hill, Andrew F ^a   Sernee, M Fleur ^a   Masters, Colin L ^a   Small, David H ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Amyloid; A ; Proteasome; secretase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; PEPTIDE; PROTEASOME; RECOMBINANT PROTEIN; TYROSYLGLUTAMYLASPARAGINYLPROLYLTHREONYLTYROSINAMIDE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; BRAIN FUNCTION; CARBOXY TERMINAL SEQUENCE; CHO CELL; CONTROLLED STUDY; CYTOSOL; GENE MUTATION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CYSTEINE ENDOPEPTIDASES; FEMALE; MASS SPECTROMETRY; MULTIENZYME COMPLEXES; MUTAGENESIS; OVARY; PEPTIDE FRAGMENTS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RECOMBINANT PROTEINS; SYNTENY; TRANSFECTION;

EID: 0242330370     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10646     Document Type: Article

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