Mechanisms of clinical resistance to small molecule tyrosine kinase inhibitors targeting oncogenic tyrosine kinases

American Journal of PharmacoGenomics

Volumn 5, Issue 2, 2005, Pages 101-112

  Van Der Kuip, Heiko ^a   Wohlbold, Lara ^a   Oetzel, Carsten ^b   Schwab, Matthias ^a   Aulitzky, Walter E ^b  

^a DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^b ROBERT BOSCH HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

6 (4 HYDROXYPHENYL) 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; BCR ABL PROTEIN; CANERTINIB; CEP 701; CP 724714; EPIDERMAL GROWTH FACTOR; ERLOTINIB; GEFITINIB; IMATINIB; LAPATINIB; MIDOSTAURIN; PELITINIB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE INHIBITOR; STEM CELL FACTOR RECEPTOR; SU 11654; SUNITINIB; UNCLASSIFIED DRUG;

DRUG BIOAVAILABILITY; DRUG RESISTANCE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; GENE MUTATION; HUMAN; NONHUMAN; PHARMACOGENOMICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; TREATMENT FAILURE;

ANIMALS; DRUG RESISTANCE, NEOPLASM; HUMANS; MUTATION; NEOPLASMS; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; PYRIMIDINES;

EID: 17844409079     PISSN: 11752203     EISSN: None     Source Type: Journal    
DOI: 10.2165/00129785-200505020-00003     Document Type: Review

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