-
1
-
-
0035220605
-
Biological and clinical significance of HER2 overexpression in breast cancer
-
Kurebayashi J: Biological and clinical significance of HER2 overexpression in breast cancer. Breast Cancer 8:45-51, 2001.
-
(2001)
Breast Cancer
, vol.8
, pp. 45-51
-
-
Kurebayashi, J.1
-
3
-
-
0037010076
-
Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia
-
Arteaga CL: Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia. Semin Oncol 5 (Suppl 14) :3-9, 2002. (Pubitemid 35191041)
-
(2002)
Seminars in Oncology
, vol.29
, Issue.SUPPL. 14
, pp. 3-9
-
-
Arteaga, C.L.1
-
4
-
-
6044259839
-
Endocrine-resistant breast cancer: Underlying mechanisms and strategies for overcoming resistance
-
Kurebayashi J: Endocrine-resistant breast cancer: underlying mechanisms and strategies for overcoming resistance. Breast Cancer 10:112-119, 2003.
-
(2003)
Breast Cancer
, vol.10
, pp. 112-119
-
-
Kurebayashi, J.1
-
5
-
-
0024531977
-
Expression of epidermal growth factor receptors associated with lack of response to endocrine therapy in recurrent breast cancer
-
Nicholson S, Sainsbury JR, Halcrow P, Chambers P, Farndon JR, Harris AL: Expression of epidermal growth factor receptors associated with lack of response to endocrine therapy in recurrent breast cancer. Lancet i (8631):182-185, 1989. (Pubitemid 19038803)
-
(1989)
Lancet
, vol.1
, Issue.8631
, pp. 182-185
-
-
Nicholson, S.1
Halcrow, P.2
Farndon, J.R.3
Sainsbury, J.R.C.4
Chambers, P.5
Harris, A.L.6
-
6
-
-
0026786658
-
Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells
-
van Agthoven T, van Agthoven TL, Portengen H, Foekens JA, Dorssers LC: Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells. Cancer Res 52:5082-5088, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 5082-5088
-
-
Van Agthoven, T.1
Van Agthoven, T.L.2
Portengen, H.3
Foekens, J.A.4
Dorssers, L.C.5
-
7
-
-
0028886694
-
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
-
Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H, Masushige S, Gotoh Y, Nishida E, Kawashima H: Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270:1491-1494, 1995.
-
(1995)
Science
, vol.270
, pp. 1491-1494
-
-
Kato, S.1
Endoh, H.2
Masuhiro, Y.3
Kitamoto, T.4
Uchiyama, S.5
Sasaki, H.6
Masushige, S.7
Gotoh, Y.8
Nishida, E.9
Kawashima, H.10
-
8
-
-
0029877913
-
Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
-
Bunone G, Briand PA, Miksicek RJ, Picard D: Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J 15:2174-2183, 1996. (Pubitemid 26141134)
-
(1996)
EMBO Journal
, vol.15
, Issue.9
, pp. 2174-2183
-
-
Bunone, G.1
Briand, P.-A.2
Miksicek, R.J.3
Picard, D.4
-
9
-
-
0033636597
-
Activation of estrogen receptor alpha by S118 phosphorylation involves a liganddependent interaction with TFIIH and participation of CDK7
-
Chen D, Riedl T, Washbrook E, Pace PE, Coombes RC, Egly JM, Ali S: Activation of estrogen receptor alpha by S118 phosphorylation involves a liganddependent interaction with TFIIH and participation of CDK7. Mol Cell 6:127-137, 2000.
-
(2000)
Mol Cell
, vol.6
, pp. 127-137
-
-
Chen, D.1
Riedl, T.2
Washbrook, E.3
Pace, P.E.4
Coombes, R.C.5
Egly, J.M.6
Ali, S.7
-
10
-
-
0035664786
-
Inhibition of erbB receptor (HER) tyrosine kinases as a strategy to abrogate antiestrogen resistance in human breast cancer
-
Kurokawa H, Arteaga CL: Inhibition of erbB receptor (HER) tyrosine kinases as a strategy to abrogate antiestrogen resistance in human breast cancer. Clin Cancer Res 7 (12 Suppl):4436s-4442s, 2001. (Pubitemid 34031593)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.SUPPL. 12
-
-
Kurokawa, H.1
Arteaga, C.L.2
-
11
-
-
0034526749
-
A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I
-
DOI 10.1210/en.141.12.4503
-
Martin MB, Franke TF, Stoica GE, Chambon P, Katzenellenbogen BS, Stoica BA, McLemore MS, Olivo SE, Stoica A: A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I. Endocrinology 141:4503-4511, 2000. (Pubitemid 32055127)
-
(2000)
Endocrinology
, vol.141
, Issue.12
, pp. 4503-4511
-
-
Martin, M.B.1
Franke, T.F.2
Stoica, G.E.3
Chambon, P.4
Katzenellenbogen, B.S.5
Stoica, B.A.6
McLemore, M.S.7
Olivo, S.E.8
Stoica, A.9
-
12
-
-
0035971181
-
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
-
Campbell RA, Bhat-Nakshatri P, Patel NM, Constanfinidou D, Ali S, Nakshatri H: Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem 276:9817-9824, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 9817-9824
-
-
Campbell, R.A.1
Bhat-Nakshatri, P.2
Patel, N.M.3
Constanfinidou, D.4
Ali, S.5
Nakshatri, H.6
-
13
-
-
0037296357
-
The epidermal growth factor receptor-tyrosine kinase: A promising therapeutic target in solid tumors
-
DOI 10.1053/sonc.2003.50015
-
Ritter CA, Arteaga CL: The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors. Semin Oncol 30 (1 Suppl 1):3-11, 2003. (Pubitemid 36307612)
-
(2003)
Seminars in Oncology
, vol.30
, Issue.SUPPL. 1
, pp. 3-11
-
-
Ritter, C.A.1
Arteaga, C.L.2
-
14
-
-
84858121144
-
Prognostic and predictive values of HER1 and HER,? overexpression in breast cancer
-
Yamamoto Y: Prognostic and predictive values of HER1 and HER,? overexpression in breast cancer. Kawasaki Igakkaishi 29:47-58, 2003.
-
(2003)
Kawasaki Igakkaishi
, vol.29
, pp. 47-58
-
-
Yamamoto, Y.1
-
15
-
-
0035893560
-
Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo
-
Moulder SL, Yakes FM, Muthuswamy SK, Bianco R, Simpson JF, Arteaga CL: Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Cancer Res 61:8887-8895, 2001. (Pubitemid 34013905)
-
(2001)
Cancer Research
, vol.61
, Issue.24
, pp. 8887-8895
-
-
Moulder, S.L.1
Yakes, F.M.2
Muthuswamy, S.K.3
Bianco, R.4
Simpson, J.F.5
Arteaga, C.L.6
-
16
-
-
0036777281
-
The role of EGFR-directed therapy in the treatment of breast cancer
-
Morris C: The role of EGFR-directed therapy in the treatment of breast cancer. Breast Cancer Res Treat 75 (Suppl 1):S51-S55, 2002. (Pubitemid 35015090)
-
(2002)
Breast Cancer Research and Treatment
, vol.75
, Issue.SUPPL. 1
-
-
Morris, C.1
-
17
-
-
84858123229
-
The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 ('Iressa') enhances the antitumor effect of the antiestrogen ICI 182, 780 ('Faslodex') in estrogen-receptor-positive breast cancer cells
-
Kurebayashi J, Okubo S, Yamamoto Y, Otsuki T, Sonoo H: The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 ('Iressa') enhances the antitumor effect of the antiestrogen ICI 182,780 ('Faslodex') in estrogen-receptor-positive breast cancer cells. Breast Cancer Res Treat 76 (Suppl 1):S71, 2002.
-
(2002)
Breast Cancer Res Treat
, vol.76
, Issue.SUPPL. 1
-
-
Kurebayashi, J.1
Okubo, S.2
Yamamoto, Y.3
Otsuki, T.4
Sonoo, H.5
-
18
-
-
0037241504
-
Integration of signal transduction inhibitors with endocrine therapy: An approach to overcoming hormone resistance in breast cancer
-
Johnston SR, Head J, Pancholi S, Detre S, Martin LA, Smith IE, Dowsett M: Integration of signal transducfion inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer. Clin Cancer Res 9:524S-532S, 2003. (Pubitemid 36105797)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.II1
-
-
Johnston, S.R.D.1
Head, J.2
Pancholi, S.3
Detre, S.4
Martin, L.-A.5
Smith, I.E.6
Dowsett, M.7
-
19
-
-
0036362221
-
Epidermal growth factor receptor dependence in human tumors: More than just expression?
-
Arteaga CL: Epidermal growth factor receptor dependence in human tumors: more than just expression? Oncologist 7 (Suppl 4):31-39, 2002. (Pubitemid 34977161)
-
(2002)
Oncologist
, vol.7
, Issue.SUPPL. 4
, pp. 31-39
-
-
Arteaga, C.L.1
-
20
-
-
0036842170
-
Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types
-
DOI 10.1200/JCO.2002.03.100
-
Baselga J, Rischin D, Ranson M, Calvert H, Raymond E, Kieback DG, Kaye SB, Gianni L, Harris A, Bjork T, Averbuch SD, Feyereislova A, Swaisland H, Rojo F, Albanell J: Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. J Clin Onco1 20:4292-4302, 2002. (Pubitemid 35266289)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.21
, pp. 4292-4302
-
-
Baselga, J.1
Rischin, D.2
Ranson, M.3
Calvert, H.4
Raymond, E.5
Kieback, D.G.6
Kaye, S.B.7
Gianni, L.8
Harris, A.9
Bjork, T.10
Averbuch, S.D.11
Feyereislova, A.12
Swaisland, H.13
Rojo, F.14
Albanell, J.15
-
21
-
-
0037106377
-
Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: Results of a phase i trial
-
Herbst RS, Maddox AM, Rothenberg ML, Small EJ, Rubin EH, Baselga J, Rojo F, Hong WK, Swaisland H, Averbuch SD, Ochs J, LoRusso PM: Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial. J Clin Onco1 20:3815-3825, 2002.
-
(2002)
J Clin Onco1
, vol.20
, pp. 3815-3825
-
-
Herbst, R.S.1
Maddox, A.M.2
Rothenberg, M.L.3
Small, E.J.4
Rubin, E.H.5
Baselga, J.6
Rojo, F.7
Hong, W.K.8
Swaisland, H.9
Averbuch, S.D.10
Ochs, J.11
Lorusso, P.M.12
-
22
-
-
0036569870
-
ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: Results of a phase I trial
-
DOI 10.1200/JCO.2002.10.112
-
Ranson M, Hammond LA, Ferry D, Kris M, Tullo A, Murray PI, Miller V, Averbuch S, Ochs J, Morris C, Feyereislova A, Swaisland H, Rowinsky EK: ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase T trial. J Clin Onco1 20:2240-2250, 2002. (Pubitemid 34441651)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.9
, pp. 2240-2250
-
-
Ranson, M.1
Hammond, L.A.2
Ferry, D.3
Kris, M.4
Tullo, A.5
Murray, P.I.6
Miller, V.7
Averbuch, S.8
Ochs, J.9
Morris, C.10
Feyereislova, A.11
Swaisland, H.12
Rowinsky, E.K.13
-
23
-
-
0037431759
-
Severe acute interstitial pneumonia and gefitinib
-
DOI 10.1016/S0140-6736(03)12190-3
-
Inoue A, Saijo Y, Maemondo M, Gomi K, Tokue Y, Kimura Y, Ebina M, Kikuchi T, Moriya T, Nukiwa T: Severe acute interstitial pneumonia and gefitinib. Lancet 361 (9352):137-139, 2003. (Pubitemid 36092019)
-
(2003)
Lancet
, vol.361
, Issue.9352
, pp. 137-139
-
-
Inoue, A.1
Saijo, Y.2
Maemondo, M.3
Gomi, K.4
Tokue, Y.5
Kimura, Y.6
Ebina, M.7
Kikuchi, T.8
Moriya, T.9
Nukiwa, T.10
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