Gene dosage PCR and fluorescence in situ hybridization reveal low frequency of egfr amplifications despite protein overexpression in invasive breast carcinoma

Laboratory Investigation

Volumn 84, Issue 5, 2004, Pages 582-587

  Kersting, Christian ^a   Tidow, Nicola ^a   Schmidt, Hartmut ^a   Liedtke, Cornelia ^a   Neumann, Joerg ^a   Boecker, Werner ^a   Van Diest, Paul J ^b   Brandt, Burkhard ^a   Buerger, Horst ^a,c  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Amplification; Breast; Carcinoma; EGFR; FISH; Gene dosage PCR; IH; Overexpression

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; DNA;

ARTICLE; BREAST CARCINOMA; CANCER INVASION; CANCER STAGING; CONTROLLED STUDY; DNA EXTRACTION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DOSAGE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRON; POLYMERASE CHAIN REACTION; POLYMORPHIC LOCUS; PRIORITY JOURNAL; BREAST TUMOR; GENE EXPRESSION; GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY;

BASE SEQUENCE; BREAST NEOPLASMS; DNA, NEOPLASM; FEMALE; GENE AMPLIFICATION; GENE DOSAGE; GENE EXPRESSION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; NEOPLASM INVASIVENESS; NEOPLASM STAGING; POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 2942629610     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700077     Document Type: Article

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