Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

Blood

Volumn 102, Issue 1, 2003, Pages 276-283

  Branford, Susan ^a   Rudzki, Zbigniew ^a   Walsh, Sonya ^a   Parkinson, Ian ^a   Grigg, Andrew ^a   Szer, Jeff ^a   Taylor, Kerry ^a   Herrmann, Richard ^a   Seymour, John F ^a   Arthur, Chris ^a   Joske, David ^a   Lynch, Kevin ^a   Hughes, Tim ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BCR ABL PROTEIN; IMATINIB; PHOSPHATE BINDING AGENT;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; CYTOGENETICS; DIAGNOSTIC VALUE; DISEASE MARKER; DRUG EFFICACY; FEMALE; FOLLOW UP; GENE MUTATION; GENETIC ANALYSIS; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; SEQUENCE ANALYSIS; SIDE EFFECT; TIME SERIES ANALYSIS;

EID: 10744232328     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-09-2896     Document Type: Article

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