Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

Journal of Biological Chemistry

Volumn 277, Issue 48, 2002, Pages 46265-46272

  Stamos, Jennifer ^a   Sliwkowski, Mark X ^a   Eigenbrot, Charles ^a,b  

^a GENENTECH INC   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CRYSTAL STRUCTURE; OLIGOMERS; TUMORS;

PHOSPHORYLATION;

ENZYMES;

4 ANILINOQUINAZOLINE; AMINO ACID; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; ERLOTINIB; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN;

AMINO ACID MOTIFS; ANIMALS; CATALYTIC DOMAIN; CELL LINE; CRYSTALLOGRAPHY; ENZYME ACTIVATION; ENZYME INHIBITORS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SPODOPTERA;

EID: 0141599428     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207135200     Document Type: Article

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