-
1
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996;2:561-566.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
2
-
-
15444350807
-
Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148)
-
Beran M, Cao X, Estrov Z, et al. Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148). Clin Cancer Res. 1998;4:1661-1672.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1661-1672
-
-
Beran, M.1
Cao, X.2
Estrov, Z.3
-
3
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-1037.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
4
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001; 344:1038-1042.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
-
5
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian H, Sawyers C, Hochhaus A, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med. 2002;346:645-652.
-
(2002)
N Engl J Med
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
-
6
-
-
0037085785
-
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
-
Talpaz M, Silver R, Druker B, et al. Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood. 2002;99:1928-1937.
-
(2002)
Blood
, vol.99
, pp. 1928-1937
-
-
Talpaz, M.1
Silver, R.2
Druker, B.3
-
7
-
-
0037092980
-
Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase
-
Kantarjian H, Cortes J, O'Brien S, et al. Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase. Blood. 2002;99:3547-3553.
-
(2002)
Blood
, vol.99
, pp. 3547-3553
-
-
Kantarjian, H.1
Cortes, J.2
O'Brien, S.3
-
8
-
-
0000869570
-
A phase II study to determine the safety and antileukemic effects of STI571 in patients with Philadelphia chromosome positive chronic myeloid leukemia in myeloid blast crisis
-
Sawyers C, Hochhaus A, Feldman E, et al. A phase II study to determine the safety and antileukemic effects of STI571 in patients with Philadelphia chromosome positive chronic myeloid leukemia in myeloid blast crisis [abstract]. Blood. 2000;96:503a.
-
(2000)
Blood
, vol.96
-
-
Sawyers, C.1
Hochhaus, A.2
Feldman, E.3
-
9
-
-
0035992329
-
Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: Follow-up results
-
Kantarjian H, Talpaz M, O'Brien S, et al. Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: follow-up results. Clin Cancer Res. 2002;8:2177-2187.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2177-2187
-
-
Kantarjian, H.1
Talpaz, M.2
O'Brien, S.3
-
10
-
-
0034210577
-
Mechanism of resistance to the ABL tyrosine kinase inhibitor STI571 in BCR/ABL-transformed hematopoietic cell lines
-
Weisberg E, Griffin JD. Mechanism of resistance to the ABL tyrosine kinase inhibitor STI571 in BCR/ABL-transformed hematopoietic cell lines. Blood. 2000;95:3498-3505.
-
(2000)
Blood
, vol.95
, pp. 3498-3505
-
-
Weisberg, E.1
Griffin, J.D.2
-
11
-
-
0034254368
-
Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: Diverse mechanism of resistance
-
Mahon FX, Deininger MWN, Schultheis B, et al. Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanism of resistance. Blood. 2000;96:1070-1079.
-
(2000)
Blood
, vol.96
, pp. 1070-1079
-
-
Mahon, F.X.1
Deininger, M.W.N.2
Schultheis, B.3
-
12
-
-
0035800507
-
Clinical resistance to STI571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science. 2001;293:876-880.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
13
-
-
0035929673
-
Roots of clinical resistance to STI-571 cancer therapy
-
Hochhaus A, Kreil S, Corbin A, et al. Roots of clinical resistance to STI-571 cancer therapy. Science. 2001;293:2163.
-
(2001)
Science
, vol.293
, pp. 2163
-
-
Hochhaus, A.1
Kreil, S.2
Corbin, A.3
-
14
-
-
0035895106
-
Restoration of sensitivity to STI571 in STI571-resistant chronic myeloid leukemia cells
-
Tipping A, Manhon FX, Lagarde V, Goldman JM, Melo JV. Restoration of sensitivity to STI571 in STI571-resistant chronic myeloid leukemia cells. Blood. 2001;98:3864-3867.
-
(2001)
Blood
, vol.98
, pp. 3864-3867
-
-
Tipping, A.1
Manhon, F.X.2
Lagarde, V.3
Goldman, J.M.4
Melo, J.V.5
-
15
-
-
0035122485
-
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase
-
Vigneri P, Wang JYJ. Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nat Med. 2001;7:228-234.
-
(2001)
Nat Med
, vol.7
, pp. 228-234
-
-
Vigneri, P.1
Wang, J.Y.J.2
-
16
-
-
0037045583
-
BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: A prospective study
-
von Bubnoff N, Schneller F, Peschel C, Duyster J. BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study. Lancet. 2001;359:487-491.
-
(2001)
Lancet
, vol.359
, pp. 487-491
-
-
Von Bubnoff, N.1
Schneller, F.2
Peschel, C.3
Duyster, J.4
-
17
-
-
0034684075
-
Role of alpha 1 acid glycoprotein in the in vivo resistance of human BCR-ABL+ leukemia cells to the Abl inhibitor STI571
-
Gambacorti-Passerini C, Barni R, Le Coutre P. Role of alpha 1 acid glycoprotein in the in vivo resistance of human BCR-ABL+ leukemia cells to the Abl inhibitor STI571. J Natl Cancer Inst. 2000;18;92:1641-1650.
-
(2000)
J Natl Cancer Inst
, vol.18
, Issue.92
, pp. 1641-1650
-
-
Gambacorti-Passerini, C.1
Barni, R.2
Le Coutre, P.3
-
18
-
-
0034161460
-
Induction of resistance to the Abelson inhibitor STI571 in human leukemic cells through gene amplification
-
Le Coutre P, Tassi E, Varella-Garcia M, et al. Induction of resistance to the Abelson inhibitor STI571 in human leukemic cells through gene amplification. Blood. 2000;95:1758-1766.
-
(2000)
Blood
, vol.95
, pp. 1758-1766
-
-
Le Coutre, P.1
Tassi, E.2
Varella-Garcia, M.3
-
19
-
-
0036566540
-
High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance
-
Branford S, Rudzki Z, Walsh S, et al. High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance. Blood. 2002;99:3472-3475.
-
(2002)
Blood
, vol.99
, pp. 3472-3475
-
-
Branford, S.1
Rudzki, Z.2
Walsh, S.3
-
20
-
-
0034667856
-
Homoharringtonine and low-dose cytarabine in the management of late chronic-phase chronic myelogenous leukemia
-
Kantarjian HM, Talpaz M, Smith TL, et al. Homoharringtonine and low-dose cytarabine in the management of late chronic-phase chronic myelogenous leukemia. J Clin Oncol. 2000;18:3513-3521.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3513-3521
-
-
Kantarjian, H.M.1
Talpaz, M.2
Smith, T.L.3
-
21
-
-
16944363756
-
Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia
-
Kantarjian HM, O'Brien SM, Keating M, et al. Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia. Leukemia. 1997;11:1617-1620.
-
(1997)
Leukemia
, vol.11
, pp. 1617-1620
-
-
Kantarjian, H.M.1
O'Brien, S.M.2
Keating, M.3
-
22
-
-
0035282901
-
Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia
-
Peters D, Hoover R, Gerlach M, et al. Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia. Blood. 2001;97:1404-1412.
-
(2001)
Blood
, vol.97
, pp. 1404-1412
-
-
Peters, D.1
Hoover, R.2
Gerlach, M.3
-
23
-
-
4243970519
-
High-dose imatinib mesylate (STI571, gleevec) in patients with chronic myeloid leukemia (CML) resistant or intolerant to interferon-alpha (IFN)
-
Cortes J, Talpaz M, Giles F, et al. High-dose imatinib mesylate (STI571, gleevec) in patients with chronic myeloid leukemia (CML) resistant or intolerant to interferon-alpha (IFN) [abstract]. Proc ASCO. 2002;21:262a.
-
(2002)
Proc ASCO
, vol.21
-
-
Cortes, J.1
Talpaz, M.2
Giles, F.3
-
24
-
-
0003215157
-
High rates of early major and complete cytogenetic responses with imatinib mesylate therapy given at 400 mg or 800 mg orally daily in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase (Ph + CML-CP)
-
Kantarjian H, Cortes J, O'Brien S, et al. High rates of early major and complete cytogenetic responses with imatinib mesylate therapy given at 400 mg or 800 mg orally daily in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase (Ph + CML-CP) [abstract]. Proc ASCO. 2002;21: 261a.
-
(2002)
Proc ASCO
, vol.21
-
-
Kantarjian, H.1
Cortes, J.2
O'Brien, S.3
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