Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

Pharmacogenetics

Volumn 12, Issue 8, 2002, Pages 591-595

  Kerb, Reinhold ^a   Brinkmann, Ulrich ^a   Chatskaia, Natalia ^b   Gorbunov, Dmitry ^b   Gorboulev, Valentin ^b   Mornhinweg, Esther ^a   Keil, Andrea ^a   Eichelbaum, Michel ^c   Koepsell, Hermann ^b  

^a Epidauros Biotechnologie AG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

Author keywords

Drug transport; Organic cation transporter; Polymorphisms

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ARGININE; CYSTEINE; GLYCINE; LEUCINE; METHIONINE; NEUROTRANSMITTER; ORGANIC CATION TRANSPORTER; PHENYLALANINE; SEROTONIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CAUCASIAN; CONTROLLED STUDY; DRUG DISPOSITION; DRUG EFFECT; DRUG SELECTIVITY; DRUG TRANSPORT; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; MALE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; XENOPUS;

ADULT; ANIMALS; BASE SEQUENCE; DNA PRIMERS; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; ORGANIC CATION TRANSPORTER 1; RECOMBINANT PROTEINS; VARIATION (GENETICS); XENOPUS;

EID: 0036865724     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200211000-00002     Document Type: Article

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