Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

EMBO Journal

Volumn 16, Issue 18, 1997, Pages 5572-5581

  Hubbard, Stevan R ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autophosphorylation; Insulin receptor; Protein tyrosine kinase; Substrate specificity; X ray crystallography

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; INSULIN RECEPTOR; PROTEIN TYROSINE KINASE;

ARTICLE; AUTOPHOSPHORYLATION; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SPECIFICITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ADENYLYL IMIDODIPHOSPHATE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, INSULIN; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0030766163     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.18.5572     Document Type: Article

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