-
1
-
-
0037041420
-
Inherenttoxity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini M, E Giannoni, F Chiti, F Baroni, L Formigli, J Zurdo, N Taddel, G Ramponi, C Dobson and M Stefani (2002) Inherent toxity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416, 507-511.
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddel, N.7
Ramponi, G.8
Dobson, C.9
Stefani, M.10
-
2
-
-
0035163412
-
Solubility of α-synuclein differs between multiple system atrophy and dementia with Lewy bodies
-
Campbell BC, CA McLean, JG Culvenor, WP Gai, PC Blumbergs, P Jakala, K Beyreuther, CL Masters and QX Li (2001) Solubility of α-synuclein differs between multiple system atrophy and dementia with Lewy bodies. J. Neurochem. 76, 87-96.
-
(2001)
J. Neurochem.
, vol.76
, pp. 87-96
-
-
Campbell, B.C.1
McLean, C.A.2
Culvenor, J.G.3
Gai, W.P.4
Blumbergs, P.C.5
Jakala, P.6
Beyreuther, K.7
Masters, C.L.8
Li, Q.X.9
-
3
-
-
4644290985
-
α-Synuclein locus duplication as a cause of familial Parkinson's disease
-
Chartier-Harlin MC, J Kachergus, C Roumier, V Mouroux, X Douay, S Lincoln, C Levecque, L Larvor, J Andrieux, M Hulihan, N Waucquier, L Defebvre, P Amouyel, M Farrer and A Destee (2004) α-Synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 364, 1167-1169.
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hulihan, M.10
Waucquier, N.11
Defebvre, L.12
Amouyel, P.13
Farrer, M.14
Destee, A.15
-
4
-
-
0035903813
-
Co-association f parkin and α-synuclein
-
Choi P, N Golts, H Snyder, M Chong, L Petrucelli, J Hardy, D Sparkman, E Cochran, JM Lee and B Wolozin (2001) Co-association f parkin and α-synuclein. Neuroreport 12, 2839-2843.
-
(2001)
Neuroreport
, vol.12
, pp. 2839-2843
-
-
Choi, P.1
Golts, N.2
Snyder, H.3
Chong, M.4
Petrucelli, L.5
Hardy, J.6
Sparkman, D.7
Cochran, E.8
Lee, J.M.9
Wolozin, B.10
-
5
-
-
0034646391
-
Fibrils formed in vitro from α-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid
-
Conway K, J Harper and PT Lansbury (2000a) Fibrils formed in vitro from α-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid. Biochemistry 39, 2552-2563.
-
(2000)
Biochemistry
, vol.39
, pp. 2552-2563
-
-
Conway, K.1
Harper, J.2
Lansbury, P.T.3
-
6
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
-
Conway KA, S Lee, J Rochet, T Ding, R Williamson and P Lansbury Jr (2000b) Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy. Proc. Natl. Acad. Sci. USA 99, 571-576.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.2
Rochet, J.3
Ding, T.4
Williamson, R.5
Lansbury Jr., P.6
-
7
-
-
0038380524
-
Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease
-
Crocker S J, PD Smith, V Jackson-Lewis, WR Lamba, SP Hayley, E Grimm, SM Callaghan, RS Slack, E Melloni, S Przedborski, GS Robertson, H Anisman, Z Merali and DS Park (2003) Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. J. Neurosci. 23, 4081-4091.
-
(2003)
J. Neurosci.
, vol.23
, pp. 4081-4091
-
-
Crocker, S.J.1
Smith, P.D.2
Jackson-Lewis, V.3
Lamba, W.R.4
Hayley, S.P.5
Grimm, E.6
Callaghan, S.M.7
Slack, R.S.8
Melloni, E.9
Przedborski, S.10
Robertson, G.S.11
Anisman, H.12
Merali, Z.13
Park, D.S.14
-
8
-
-
4344659685
-
Impaired degradation of mutant C -synuclein by chaperone-mediated autophagy
-
Cuervo AM, L Stefanis, R Fredenburg, PT Lansbury and D Sulzer (2004) Impaired degradation of mutant C -synuclein by chaperone-mediated autophagy. Science 305, 1292-1295.
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
9
-
-
0032540327
-
Stabilization of ?-synuclein secondary structure upon binding to synthetic membranes
-
Davidson WS, A Jonas, DF Clayton and JM George (1998) Stabilization of ?-synuclein secondary structure upon binding to synthetic membranes. J. Biol. Chem. 273, 9443-9449.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9443-9449
-
-
Davidson, W.S.1
Jonas, A.2
Clayton, D.F.3
George, J.M.4
-
10
-
-
0037072284
-
Annular α-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain derived membranes
-
Ding T, S Lee, J Rochet and PT Lansbury (2002) Annular α-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain derived membranes. Biochemistry 41, 10209-10217.
-
(2002)
Biochemistry
, vol.41
, pp. 10209-10217
-
-
Ding, T.1
Lee, S.2
Rochet, J.3
Lansbury, P.T.4
-
11
-
-
0035815115
-
Conformational properties of α-synuclein in its free and lipidassociated states
-
Eliezer D, E Kutluay, R Bussell and G Browne (2001) Conformational properties of α-synuclein in its free and lipidassociated states. J. Mol. Biol. 307, 10661-10673.
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 10661-10673
-
-
Eliezer, D.1
Kutluay, E.2
Bussell, R.3
Browne, G.4
-
12
-
-
0030741317
-
The heptameric prepore of a staphylococcal ?-hemolysin mutant in lipid bilayers imaged by atomic force microscopy
-
Fang Y, S Cheley, H Bayley and J Yang (1997) The heptameric prepore of a staphylococcal ?-hemolysin mutant in lipid bilayers imaged by atomic force microscopy. Biochemistry 36, 9518-9522.
-
(1997)
Biochemistry
, vol.36
, pp. 9518-9522
-
-
Fang, Y.1
Cheley, S.2
Bayley, H.3
Yang, J.4
-
13
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany MB and WW Bender (2000) A Drosophila model of Parkinson's disease. Nature 404, 394-398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
14
-
-
0035954729
-
Antibacterial agents based on the cyclic D,L-α-peptide architecture
-
Fernandez-Lopez S, H-S Kim, EC Choi, M M Delgado, JR Granja, A Khasanov, K Kraehenbuehl, G Long, DA Weinberger, KM Wilcox n and MR Ghadiri (2001) Antibacterial agents based on the cyclic D,L-α-peptide architecture. Nature 412, 452-455.
-
(2001)
Nature
, vol.412
, pp. 452-455
-
-
Fernandez-Lopez, S.1
Kim, H.-S.2
Choi, E.C.M.3
Delgado, M.4
Granja, J.R.5
Khasanov, A.6
Kraehenbuehl, K.7
Long, G.8
Weinberger, D.A.9
Wilcoxen, K.M.10
Ghadiri, M.R.11
-
15
-
-
0036005859
-
Maging and manipulation of biological structures with the AFM
-
Fotiadis D, S Scheuring, SA Muller, A Engel and DJ Muller (2002) maging and manipulation of biological structures with the AFM. Micron 33, 385-397.
-
(2002)
Micron
, vol.33
, pp. 385-397
-
-
Fotiadis, D.1
Scheuring, S.2
Muller, S.A.3
Engel, A.4
Muller, D.J.5
-
17
-
-
0032692501
-
α-Synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components
-
Gai WP, JHT Power, PC Biumbergs, JG Culvenor and PH Jensen (1999) α-Synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components. J. Neurochem. 73, 2093-2100.
-
(1999)
J. Neurochem.
, vol.73
, pp. 2093-2100
-
-
Gai, W.P.1
Power, J.H.T.2
Biumbergs, P.C.3
Culvenor, J.G.4
Jensen, P.H.5
-
18
-
-
0033669319
-
In situ and in vitro study of colocalization and segregation of α-synuclein, ubiquitin and lipids in cortical Lewy bodies
-
Gai WP, HX Yuan, QX Li, JHT Power, PC Blumbergs and PH Jensen (2000) In situ and in vitro study of colocalization and segregation of α-synuclein, ubiquitin and lipids in cortical Lewy bodies. Exp. Neurol. 166, 324-333.
-
(2000)
Exp. Neurol.
, vol.166
, pp. 324-333
-
-
Gai, W.P.1
Yuan, H.X.2
Li, Q.X.3
Power, J.H.T.4
Blumbergs, P.C.5
Jensen, P.H.6
-
19
-
-
0037404112
-
α-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy
-
Gai WP, DL Pountney, JHT Power, QX Li, JG Culvenor, CA McLean, PH Jensen and PC Blumbergs (2003) α-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy. Exp. Neurol. 181, 68-78.
-
(2003)
Exp. Neurol.
, vol.181
, pp. 68-78
-
-
Gai, W.P.1
Pountney, D.L.2
Power, J.H.T.3
Li, Q.X.4
Culvenor, J.G.5
McLean, C.A.6
Jensen, P.H.7
Blumbergs, P.C.8
-
20
-
-
0035409575
-
α-Synuclein and neurodegenerative diseases
-
Goedert M (2001) α-Synuclein and neurodegenerative diseases. Nat. Rev. Neurosci. 2, 492-501.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 492-501
-
-
Goedert, M.1
-
21
-
-
0031789960
-
Lewy body diseases and multiple system atrophy as α-synucleinopathies
-
Goedert M and MG Spillantini (1998) Lewy body diseases and multiple system atrophy as α-synucleinopathies. Mol. Psychiatry 3, 462-465.
-
(1998)
Mol. Psychiatry
, vol.3
, pp. 462-465
-
-
Goedert, M.1
Spillantini, M.G.2
-
22
-
-
10744229371
-
The circularization of amyloid fibrils formed by apolipoprotein C-II
-
Hatters DM, CA MacRaild, R Daniels, WS Gosal, NH Thomson, JA Jones, JJ Davis, CE MacPhee, CM Dobson and GJ Howlett (2003) The circularization of amyloid fibrils formed by apolipoprotein C-II. Biophys. J. 85, 3979-3990.
-
(2003)
Biophys. J.
, vol.85
, pp. 3979-3990
-
-
Hatters, D.M.1
MacRaild, C.A.2
Daniels, R.3
Gosal, W.S.4
Thomson, N.H.5
Jones, J.A.6
Davis, J.J.7
MacPhee, C.E.8
Dobson, C.M.9
Howlett, G.J.10
-
24
-
-
0034647557
-
Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds α-synuclein filaments
-
Jensen PH, K Islam, JM Kenney, MS Nielsen, J Power and WP Gai (2000) Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds α-synuclein filaments. J. Biol. Chem. 275, 21500-21507.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21500-21507
-
-
Jensen, P.H.1
Islam, K.2
Kenney, J.M.3
Nielsen, M.S.4
Power, J.5
Gai, W.P.6
-
25
-
-
0036304315
-
Hyperphosphorylation and insolubility of α-synuclein in transgenic mouse oligodendrocytes
-
Kahle PJ, M Neumann, L Ozmen, V Muller, H Jacobsen, W Spooren, B Fuss, B Mallon, WB Macklin, H Fujiwara, M Hasegawa, T Iwatsubo, HA Kretzschmar and C Haass (2002) Hyperphosphorylation and insolubility of α-synuclein in transgenic mouse oligodendrocytes. EMBO Rep. 3, 583-588.
-
(2002)
EMBO Rep.
, vol.3
, pp. 583-588
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
Muller, V.4
Jacobsen, H.5
Spooren, W.6
Fuss, B.7
Mallon, B.8
Macklin, W.B.9
Fujiwara, H.10
Hasegawa, M.11
Iwatsubo, T.12
Kretzschmar, H.A.13
Haass, C.14
-
26
-
-
0034008852
-
Enhanced vulnerability to oxidative stress by C -synuclein mutations and C-terminal truncation
-
Kanda S, JF Bishop, MA Eglitis, Y Yang and MM Mouradian (2000) Enhanced vulnerability to oxidative stress by C -synuclein mutations and C-terminal truncation. Neuroscience 97, 279-284.
-
(2000)
Neuroscience
, vol.97
, pp. 279-284
-
-
Kanda, S.1
Bishop, J.F.2
Eglitis, M.A.3
Yang, Y.4
Mouradian, M.M.5
-
27
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno and N Shimizu (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
28
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito RR (2000) Aggresomes, inclusion bodies and protein aggregation. Trends Cell. Biol. 10, 524-530.
-
(2000)
Trends Cell. Biol.
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
29
-
-
0031990490
-
Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease
-
Kruger R, W Kuhn, T Muller, D Woitalla, M Graeber, S Kosel, H Przuntek, JT Epplen, L Schols and O Riess (1998) Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nat. Genet. 18, 106-108.
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
30
-
-
0036415838
-
α-Synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils
-
Lashuel H, B Petre, J Wall, M Simon, R Nowak, T Walz and PT Lansbury (2002) α-Synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils. J. Mol. Biol. 322, 1089-1102.
-
(2002)
J. Mol. Biol.
, vol.322
, pp. 1089-1102
-
-
Lashuel, H.1
Petre, B.2
Wall, J.3
Simon, M.4
Nowak, R.5
Walz, T.6
Lansbury, P.T.7
-
31
-
-
0037073747
-
Characterization of cytoplasmic α-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells
-
Lee HJ and SJ Lee (2002) Characterization of cytoplasmic α-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells. J. Biol. Chem. 277, 48976-48983.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48976-48983
-
-
Lee, H.J.1
Lee, S.J.2
-
32
-
-
0035949542
-
Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein
-
Li J, VN Uversky and AL Fink (2001) Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein. Biochemistry 40, 11604-11613.
-
(2001)
Biochemistry
, vol.40
, pp. 11604-11613
-
-
Li, J.1
Uversky, V.N.2
Fink, A.L.3
-
33
-
-
1842424791
-
Proteasomal inhibition by α-synuclein filaments and oligomers
-
Lindersson E, R Beedholm, P Højrup, T Moos, WP Gai, KB Hendil and PH Jensen (2004) Proteasomal inhibition by α-synuclein filaments and oligomers. J. Biol. Chem. 279, 12924-12934.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12924-12934
-
-
Lindersson, E.1
Beedholm, R.2
Højrup, P.3
Moos, T.4
Gai, W.P.5
Hendil, K.B.6
Jensen, P.H.7
-
34
-
-
9344233839
-
2+ selectively induces α-synuclein annular oligomers via interaction with the C-terminal domain
-
Epub 2004 Nov 10
-
2+ selectively induces α-synuclein annular oligomers via interaction with the C-terminal domain. Protein Sci. 13 (12), 3245-3252. Epub 2004 Nov 10.
-
(2004)
Protein Sci.
, vol.13
, Issue.12
, pp. 3245-3252
-
-
Lowe, R.1
Pountney, D.L.2
Jensen, P.H.3
Gai, W.P.4
Voelcker, N.H.5
-
36
-
-
0037931741
-
Parkinson's disease-associated α-synuclein is a calmodulin substrate
-
Martinez J, I Moeller, H Erdjument-Bromage, P Tempst and B Lauring (2003) Parkinson's disease-associated α-synuclein is a calmodulin substrate. J. Biol. Chem. 278, 17379-17387.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17379-17387
-
-
Martinez, J.1
Moeller, I.2
Erdjument-Bromage, H.3
Tempst, P.4
Lauring, B.5
-
37
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders
-
Masliah E, E Rockenstein, I Veinbergs, M Mallory, M Hashimoto, A Takeda, Y Sagara, A Sisk and L Mucke (2000) Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders. Science 287, 1265-1269.
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
38
-
-
0035859226
-
α-Synucleinenhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons
-
McLean PJ, H Kawamata and BT Hyman (2001) α-Synucleinenhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons. Neuroscience 104, 901-912.
-
(2001)
Neuroscience
, vol.104
, pp. 901-912
-
-
McLean, P.J.1
Kawamata, H.2
Hyman, B.T.3
-
39
-
-
0036456584
-
Aggresome-related biogenesis of Lewy bodies
-
McNaught KS, P Shashidharan, DP Perl, P Jenner and CW Olanow (2002) Aggresome-related biogenesis of Lewy bodies. Eur. J. Neurosci. 16, 2136-2148.
-
(2002)
Eur. J. Neurosci.
, vol.16
, pp. 2136-2148
-
-
McNaught, K.S.1
Shashidharan, P.2
Perl, D.P.3
Jenner, P.4
Olanow, C.W.5
-
40
-
-
0043233011
-
Distinct cleavage patterns of normal and pathologic forms of α-synuclein by calpain I in vitro
-
Mishizen-Eberz AJ, RP Guttmann, BI Giasson, GA Day III R Hodara, H Ischiropoulos, VM Lee, JQ Trojanowski and DR Lynch (2003) Distinct cleavage patterns of normal and pathologic forms of α-synuclein by calpain I in vitro. J. Neurochem. 86, 836-847.
-
(2003)
J. Neurochem.
, vol.86
, pp. 836-847
-
-
Mishizen-Eberz, A.J.1
Guttmann, R.P.2
Giasson, B.I.3
Day III, G.A.4
Hodara, R.5
Ischiropoulos, H.6
Lee, V.M.7
Trojanowski, J.Q.8
Lynch, D.R.9
-
42
-
-
0345189364
-
Yeast cells provide insight into α-synuclein biology and pathobiology
-
Outeiro TF and S Lindquist (2003) Yeast cells provide insight into α-synuclein biology and pathobiology. Science 302, 1772-1775.
-
(2003)
Science
, vol.302
, pp. 1772-1775
-
-
Outeiro, T.F.1
Lindquist, S.2
-
43
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, C Lavedan, E Leroy, SE Ide, A Dehejia,A Dutra, B Pike, H Root, J Rubenstein, R Boyer, ES Stenroos, S Chandrasekharappa, A Athanassiadou, T Papapetropoulos, WG Johnson, AM Lazzarini, RC Duvoisin, G Di Iorio, LI Golbe and RL Nussbaum (1997) Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
44
-
-
3142664614
-
Annular α-synuclein species from purified multiple system atrophy inclusions
-
Pountney DL, R Lowe, M Quilty, JC Vickers, NH Voelcker and WP Gai (2004) Annular α-synuclein species from purified multiple system atrophy inclusions. J. Neurochem. 90, 502-512
-
(2004)
J. Neurochem.
, vol.90
, pp. 502-512
-
-
Pountney, D.L.1
Lowe, R.2
Quilty, M.3
Vickers, J.C.4
Voelcker, N.H.5
Gai, W.P.6
-
45
-
-
0036733646
-
Non-selenium glutathione peroxidase in human brain: Elevated level in Parkinson's disease and dementia with Lewy bodies
-
Power JHT, J Shanon, PC Blumbergs and WP Gai (2002) Non-selenium glutathione peroxidase in human brain: Elevated level in Parkinson's disease and dementia with Lewy bodies. Am. J. Pathol. 161, 885-894.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 885-894
-
-
Power, J.H.T.1
Shanon, J.2
Blumbergs, P.C.3
Gai, W.P.4
-
46
-
-
0037757575
-
Localisation of α-, β- and γ-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma
-
Quilty MC, WP Gai, DL Pountney, AK West and JC Vickers (2003) Localisation of α-, β- and γ-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma. Exp. Neurol. 182, 195-207.
-
(2003)
Exp. Neurol.
, vol.182
, pp. 195-207
-
-
Quilty, M.C.1
Gai, W.P.2
Pountney, D.L.3
West, A.K.4
Vickers, J.C.5
-
47
-
-
0032869084
-
Antibody recognition imaging by force microscopy
-
Raab A, W Han, D Badt, SJ Smith-Gill, SM Lindsay, H Schindler and P Hinterdorfer (1999) Antibody recognition imaging by force microscopy. Nat. Biotech. 17, 902-905.
-
(1999)
Nat. Biotech.
, vol.17
, pp. 902-905
-
-
Raab, A.1
Han, W.2
Badt, D.3
Smith-Gill, S.J.4
Lindsay, S.M.5
Schindler, H.6
Hinterdorfer, P.7
-
48
-
-
0036095285
-
Parkin and α-synuclein interact in normal brain and colocalize in Lewy bodies of Parkinson disease
-
Schlossmacher MG, MP Frosch, WP Gai, M Medina, H Shimura, T Ochiishi, N Hattori, Y Mizuno, DJ Selkoe and KS Kosik (2002) Parkin and α-synuclein interact in normal brain and colocalize in Lewy bodies of Parkinson disease. Am. J. Pathol. 160, 1655-1667.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1655-1667
-
-
Schlossmacher, M.G.1
Frosch, M.P.2
Gai, W.P.3
Medina, M.4
Shimura, H.5
Ochiishi, T.6
Hattori, N.7
Mizuno, Y.8
Selkoe, D.J.9
Kosik, K.S.10
-
49
-
-
0035854437
-
Ubiquitination of a new form of ?-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura H, MG Schlossmacher, N Hattori, MP Frosch, A Trockenbacher, R Schneider, Y Mizuno, KS Kosik and DJ Selkoe (2001) Ubiquitination of a new form of ?-synuclein by parkin from human brain: Implications for Parkinson's disease. Science 293, 263-269.
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
50
-
-
0242300619
-
α-Synuclein locus triplication causes Parkinson's disease
-
Singleton AB, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, M Hulihan, T Peuralinna, A Dutra, R Nussbaum, S Lincoln, A Crawley, M Hanson, D Maraganore, C Adler, MR Cookson, M Muenter, M Baptista, D Miller, J Blancato, J Hardy and K Gwinn-Hardy (2003) α-Synuclein locus triplication causes Parkinson's disease. Science 302, 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
51
-
-
0038413759
-
Aggregated and monomeric α-synuclein bind to the S6′ proteasomal protein and inhibit proteasomal function
-
Snyder H, K Mensah, C Theisler, J Lee, A Matouschek and B Wolozin (2003) Aggregated and monomeric α-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function. J. Biol. Chem. 278, 11753-11759.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11753-11759
-
-
Snyder, H.1
Mensah, K.2
Theisler, C.3
Lee, J.4
Matouschek, A.5
Wolozin, B.6
-
52
-
-
0030447720
-
Structure of staphylococcal α-hemolysin, a heptameric transmembrane pore
-
Song L, MR Hobaugh, C Shustak, S Cheley, H Bayley and JE Gouaux (1996) Structure of staphylococcal α-hemolysin, a heptameric transmembrane pore. Science 274, 1859-1866.
-
(1996)
Science
, vol.274
, pp. 1859-1866
-
-
Song, L.1
Hobaugh, M.R.2
Shustak, C.3
Cheley, S.4
Bayley, H.5
Gouaux, J.E.6
-
53
-
-
0034674652
-
Dityrosine cross-linking promotes formation of stable α-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
-
Souza JM, BI Giasson, Q Chen, VM Lee and H Ischiropoulos (2000) Dityrosine cross-linking promotes formation of stable α-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies. J. Biol. Chem. 275, 18344-18349.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18344-18349
-
-
Souza, J.M.1
Giasson, B.I.2
Chen, Q.3
Lee, V.M.4
Ischiropoulos, H.5
-
54
-
-
0035449454
-
Glial cell death induced by overexpression of α-synuclein
-
Stefanova N, L Klimaschewski, W Poewe, GK Wenning and M Reindl (2001) Glial cell death induced by overexpression of α-synuclein. J. Neurosci. Res. 65, 432-438.
-
(2001)
J. Neurosci. Res.
, vol.65
, pp. 432-438
-
-
Stefanova, N.1
Klimaschewski, L.2
Poewe, W.3
Wenning, G.K.4
Reindl, M.5
-
55
-
-
0043157875
-
-
Tompkins MM, WP Gai, S Douglas and SJ Bunn (2003) α-Synuclein expression localizes to the Golgi apparatus in bovine adrenal medullary chromaffin cells. Brain Res. 984, 233-236.
-
(2003)
-
-
Tompkins, M.M.1
Gai, W.P.2
Douglas, S.3
Bunn, S.J.4
-
56
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
-
Ueda K, H Fukushima, E Masliah, Y Xia, A Iwai, M Yoshimoto, DA Otero, J Kondo, Y Ihara and T Saitoh (1993) Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA 90, 11282-11286.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
Otero, D.A.7
Kondo, J.8
Ihara, Y.9
Saitoh, T.10
-
57
-
-
0035941201
-
Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein. A possible molecular link between Parkinson's disease and heavy metal exposure
-
Uversky VN, J Li and AL Fink (2001) Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein. A possible molecular link between Parkinson's disease and heavy metal exposure. J. Biol. Chem. 276, 44284-44296.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44284-44296
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
58
-
-
0037046163
-
Vesicle permeabilization by protofibrillar α-synuclein is sensitive to Parkinson's diseaselinked mutations and occurs by a pore-like mechanism
-
Volles MJ and PT Lansbury Jr (2002) Vesicle permeabilization by protofibrillar α-synuclein is sensitive to Parkinson's diseaselinked mutations and occurs by a pore-like mechanism. Biochemistry 41, 4595-4602.
-
(2002)
Biochemistry
, vol.41
, pp. 4595-4602
-
-
Volles, M.J.1
Lansbury Jr., P.T.2
-
59
-
-
0038386274
-
Zeroing in on the pathogenic form of ?-synuclein and its mechanism of neurotoxicity in Parkinson's disease
-
Volles MJ and PT Lansbury Jr (2003) Zeroing in on the pathogenic form of ?-synuclein and its mechanism of neurotoxicity in Parkinson's disease. Biochemistry 42, 7871-7878.
-
(2003)
Biochemistry
, vol.42
, pp. 7871-7878
-
-
Volles, M.J.1
Lansbury Jr., P.T.2
-
60
-
-
0029904487
-
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
-
Weinreb PH, W Zhen, AW Poon, KA Conway and PT Lansbury Jr (1996) NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35, 13709-13715.
-
(1996)
Biochemistry
, vol.35
, pp. 13709-13715
-
-
Weinreb, P.H.1
Zhen, W.2
Poon, A.W.3
Conway, K.A.4
Lansbury Jr., P.T.5
-
62
-
-
10744230149
-
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
-
Zarranz JJ, J Alegre, JC Gomez-Esteban, E Lezcano, R Ros, I Ampuero, L Vidal, J Hoenicka, O Rodriguez, B Atares, V Llorens, E Gomez Tortosa, Tdel Ser, DG Munoz and JG de Yebenes (2004) The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia. Ann. Neurol. 55, 164-173.
-
(2004)
Ann. Neurol.
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
Llorens, V.11
Gomez Tortosa, T.12
del Ser, E.13
Munoz, D.G.14
de Yebenes, J.G.15
|