Alpha-Synuclein: Axonal transport, ligand interaction and neurodegeneration

Advances in Experimental Medicine and Biology

Volumn 487, Issue , 2001, Pages 129-134

  Jensen, P H ^a   Gai, W P ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; MICROTUBULE ASSOCIATED PROTEIN;

ALZHEIMER DISEASE; CONFERENCE PAPER; DEMENTIA; GENE MUTATION; HUNTINGTON CHOREA; NERVE DEGENERATION; NERVE FIBER TRANSPORT; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN STRUCTURE;

EID: 0034982249     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-1249-3_11     Document Type: Conference Paper

References (17)

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5. A Drosophila model of Parkinson's disease
6. NACP, a protein implicated in AIzheimer's disease and learning, is natively unfolded
7. Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: Relevance for Lewy body disease
8. Kinesin and dynein superfamily proteins and the mechanism of organelle transport
9. Axonal transport of α-synuclein is mediated by all rate components
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11. Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
12. α-synuclein binds to tau and stimulates the protein kinase A-catalysed tau phosphorylation of serine residues 262 and 356
13. Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
14. Mice lacking α-synuclein display functional deficits in the nigro-striatal dopamine system
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16. Microtubule-associated protein 1 B is a component of cortical Lewy bodies and binds α-synuclein filaments
17. Alpha-synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components