Antibacterial agents based on the cyclic D, L-α-peptide architecture

Nature

Volumn 412, Issue 6845, 2001, Pages 452-455

  Fernandez Lopez, Sara ^a   Kim, Hui Sun ^a   Choi, Ellen C ^a   Delgado, Mercedes ^a   Granja, Juan R ^a   Khasanov, Alisher ^a   Kraehenbuehl, Karin ^a   Long, Georgina ^a   Weinberger, Dana A ^a   Wilcoxen, Keith M ^a   Ghadiri, M Reza ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BACTERIA; BIOLOGICAL MEMBRANES; CELLS; DISEASES; MECHANICAL PERMEABILITY;

PEPTIDES;

DRUG DOSAGE;

ANTIINFECTIVE AGENT; CYCLIC ALPHA PEPTIDE DERIVATIVE; CYCLOPEPTIDE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

BACTERIAL DISEASE; DRUG DEVELOPMENT;

ARTICLE; BACTERIAL INFECTION; CELL DEATH; DRUG STRUCTURE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; DRUG DESIGN; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; PEPTIDES, CYCLIC; PILOT PROJECTS; STAPHYLOCOCCAL INFECTIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035954729     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35086601     Document Type: Article

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